1GXBA

Anthranilate phosphoribosyltransferase in complex with pyrophosphate and magnesium
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
343
structure length
339
Chain Sequence
MNINEILKKLINKSDLEINEAEELAKAIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRELAIKIDVPNAIDTAGGLGTVNVSTASAILLSLVNPVAKHGNRAVSGKSGSADVLEALGYNIIVPPERAKELVNKTNFVFLFAQYYHPAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSKSAYELDFNKIILVYGEPGIDEVSPIGNTFMKIVSKRGIEEVKLNVTDFGISPIPIEKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDRVGDFREGYEYADHLIEKSLDKLNEIISMNGDVTKLKTIVVKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Analysis of Two Enzymes Catalysing Reverse Metabolic Reactions Implies Common Ancestry
pubmed doi rcsb
molecule tags Transferase
molecule keywords ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE
total genus 129
structure length 339
sequence length 343
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2002-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 1gxbA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 1gxbA02
3QS8A 4X58A 4GA6A 4GKMA 4ZTVA 4M0RA 3H5QA 1O17A 4OWQA 4LHMA 5C1RA 2TPTA 4X5BA 4ZOJA 4X5DA 4ZOFA 4X5CA 2DSJA 4X46A 4GA5A 4X5EA 1KHDA 5EY3A 3QSAA 1ZVWA 1ZYKA 5BNEA 1OTPA 4OWNA 4EAFA 1BRWA 4GA4A 2WK6A 4MUOA 5EP8A 2J0FA 4GTNA 4N8QA 1ZXYA 4GIUA 3UU1A 1UOUA 1GXBA 5BYTA 3R88A 4ZOKA 4YEKA 5BO3A 2BPQA 4OWMA 5C7SA 4X59A 2GVQA 3QR9A 2ELCA 4EADA 3QQSA 3GBRA 4YI7A 1KGZA 4IJ1A 2WK5A 4HKMA 4OWVA 4OWUA 4OWSA 3R6CA 4XR5A 5BO2A 5C2LA 1V8GA 4N93A 1VQUA 3TWPA 4N5VA 1AZYA 4YYYA 4OWOA 4X5AA
chains in the Genus database with same CATH superfamily
3QS8A 4X58A 4GA6A 4GKMA 4ZTVA 4M0RA 3H5QA 1O17A 4OWQA 1RRZA 4LHMA 5C1RA 2TPTA 4X5BA 4ZOJA 4X5DA 4ZOFA 4X5CA 2DSJA 4X46A 4GA5A 4X5EA 1KHDA 5EY3A 1RF8B 3QSAA 1ZVWA 1ZYKA 5BNEA 1OTPA 4OWNA 4EAFA 1BRWA 4GA4A 2WK6A 4MUOA 5EP8A 2J0FA 4GTNA 4N8QA 1ZXYA 4GIUA 3UU1A 1UOUA 1GXBA 5BYTA 3R88A 4ZOKA 4YEKA 5BO3A 2BPQA 4OWMA 4F3FC 5C7SA 4X59A 2GVQA 3QR9A 2ELCA 4EADA 3QQSA 3GBRA 4YI7A 1KGZA 4IJ1A 2WK5A 4HKMA 4OWVA 4OWUA 4OWSA 3R6CA 4XR5A 5BO2A 5C2LA 1V8GA 4N93A 1VQUA 3TWPA 4N5VA 1AZYA 4YYYA 4OWOA 4X5AA
chains in the Genus database with same CATH topology
3QS8A 4X58A 4GA6A 4GKMA 4ZTVA 4M0RA 3H5QA 1O17A 4OWQA 4LHMA 5C1RA 2TPTA 4X5BA 4ZOJA 4X5DA 4ZOFA 4X5CA 2DSJA 4X46A 4GA5A 4X5EA 1KHDA 5EY3A 3QSAA 1ZVWA 1ZYKA 5BNEA 1OTPA 4OWNA 4EAFA 1BRWA 4GA4A 2WK6A 4MUOA 5EP8A 2J0FA 4GTNA 4N8QA 1ZXYA 4GIUA 3UU1A 1UOUA 1GXBA 5BYTA 3R88A 4ZOKA 4YEKA 5BO3A 2BPQA 4OWMA 5C7SA 4X59A 2GVQA 3QR9A 2ELCA 4EADA 3QQSA 3GBRA 4YI7A 1KGZA 4IJ1A 2WK5A 4HKMA 4OWVA 4OWUA 4OWSA 3R6CA 4XR5A 5BO2A 5C2LA 1V8GA 4N93A 1VQUA 3TWPA 4N5VA 1AZYA 4YYYA 4OWOA 4X5AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QS8 A;  4X58 A;  4GA6 A;  4GKM A;  4ZTV A;  4M0R A;  3H5Q A;  1O17 A;  4OWQ A;  4LHM A;  5C1R A;  2TPT A;  4X5B A;  4ZOJ A;  4X5D A;  4ZOF A;  4X5C A;  2DSJ A;  4X46 A;  4GA5 A;  4X5E A;  1KHD A;  5EY3 A;  3QSA A;  1ZVW A;  1ZYK A;  5BNE A;  1OTP A;  4OWN A;  4EAF A;  1BRW A;  4GA4 A;  2WK6 A;  4MUO A;  5EP8 A;  2J0F A;  4GTN A;  4N8Q A;  1ZXY A;  4GIU A;  3UU1 A;  1UOU A;  1GXB A;  5BYT A;  3R88 A;  4ZOK A;  4YEK A;  5BO3 A;  2BPQ A;  4OWM A;  5C7S A;  4X59 A;  2GVQ A;  3QR9 A;  2ELC A;  4EAD A;  3QQS A;  3GBR A;  4YI7 A;  1KGZ A;  4IJ1 A;  2WK5 A;  4HKM A;  4OWV A;  4OWU A;  4OWS A;  3R6C A;  4XR5 A;  5BO2 A;  5C2L A;  1V8G A;  4N93 A;  1VQU A;  3TWP A;  4N5V A;  1AZY A;  4YYY A;  4OWO A;  4X5A A; 
#chains in the Genus database with same CATH topology
 3QS8 A;  4X58 A;  4GA6 A;  4GKM A;  4ZTV A;  4M0R A;  3H5Q A;  1O17 A;  4OWQ A;  1RRZ A;  4LHM A;  5C1R A;  2TPT A;  4X5B A;  4ZOJ A;  4X5D A;  4ZOF A;  4X5C A;  2DSJ A;  4X46 A;  4GA5 A;  4X5E A;  1KHD A;  5EY3 A;  1RF8 B;  3QSA A;  1ZVW A;  1ZYK A;  5BNE A;  1OTP A;  4OWN A;  4EAF A;  1BRW A;  4GA4 A;  2WK6 A;  4MUO A;  5EP8 A;  2J0F A;  4GTN A;  4N8Q A;  1ZXY A;  4GIU A;  3UU1 A;  1UOU A;  1GXB A;  5BYT A;  3R88 A;  4ZOK A;  4YEK A;  5BO3 A;  2BPQ A;  4OWM A;  4F3F C;  5C7S A;  4X59 A;  2GVQ A;  3QR9 A;  2ELC A;  4EAD A;  3QQS A;  3GBR A;  4YI7 A;  1KGZ A;  4IJ1 A;  2WK5 A;  4HKM A;  4OWV A;  4OWU A;  4OWS A;  3R6C A;  4XR5 A;  5BO2 A;  5C2L A;  1V8G A;  4N93 A;  1VQU A;  3TWP A;  4N5V A;  1AZY A;  4YYY A;  4OWO A;  4X5A A; 
#chains in the Genus database with same CATH homology
 3QS8 A;  4X58 A;  4GA6 A;  4GKM A;  4ZTV A;  4M0R A;  3H5Q A;  1O17 A;  4OWQ A;  4LHM A;  5C1R A;  2TPT A;  4X5B A;  4ZOJ A;  4X5D A;  4ZOF A;  4X5C A;  2DSJ A;  4X46 A;  4GA5 A;  4X5E A;  1KHD A;  5EY3 A;  3QSA A;  1ZVW A;  1ZYK A;  5BNE A;  1OTP A;  4OWN A;  4EAF A;  1BRW A;  4GA4 A;  2WK6 A;  4MUO A;  5EP8 A;  2J0F A;  4GTN A;  4N8Q A;  1ZXY A;  4GIU A;  3UU1 A;  1UOU A;  1GXB A;  5BYT A;  3R88 A;  4ZOK A;  4YEK A;  5BO3 A;  2BPQ A;  4OWM A;  5C7S A;  4X59 A;  2GVQ A;  3QR9 A;  2ELC A;  4EAD A;  3QQS A;  3GBR A;  4YI7 A;  1KGZ A;  4IJ1 A;  2WK5 A;  4HKM A;  4OWV A;  4OWU A;  4OWS A;  3R6C A;  4XR5 A;  5BO2 A;  5C2L A;  1V8G A;  4N93 A;  1VQU A;  3TWP A;  4N5V A;  1AZY A;  4YYY A;  4OWO A;  4X5A A; 
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