1ZVWA

The crystal structure of trpd (rv2192c) from mycobacterium tuberculosis in complex with prpp and magnesium
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
346
structure length
346
Chain Sequence
PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Anthranilate phosphoribosyltransferase
total genus 107
structure length 346
sequence length 346
chains with identical sequence B
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2005-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 1zvwA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 1zvwA02
1OTPA 4OWUA 4ZTVA 4YYYA 1VQUA 4XR5A 4LHMA 4X5BA 1ZYKA 4X58A 3QS8A 4M0RA 3QQSA 1KHDA 5EP8A 2WK5A 4ZOKA 4ZOJA 5BNEA 1ZXYA 4GA5A 3GBRA 4GKMA 4OWSA 4X59A 4N93A 4GTNA 4OWVA 2ELCA 4OWNA 5BYTA 1AZYA 1UOUA 4X5EA 4ZOFA 2TPTA 4IJ1A 1GXBA 2DSJA 4X46A 4X5CA 1KGZA 2WK6A 4HKMA 3QSAA 2GVQA 1ZVWA 1V8GA 3R88A 5C2LA 5C7SA 4GIUA 4OWQA 3TWPA 3H5QA 4MUOA 3UU1A 4YEKA 4OWOA 4YI7A 3R6CA 5EY3A 4GA4A 5BO3A 4X5DA 5BO2A 2BPQA 3QR9A 4N5VA 4N8QA 4OWMA 1BRWA 4EAFA 5C1RA 4GA6A 1O17A 2J0FA 4X5AA 4EADA
chains in the Genus database with same CATH superfamily
1OTPA 4OWUA 4ZTVA 4YYYA 1VQUA 4XR5A 4LHMA 4X5BA 1ZYKA 4X58A 3QS8A 4M0RA 3QQSA 1KHDA 5EP8A 2WK5A 4ZOKA 4ZOJA 5BNEA 1ZXYA 4GA5A 3GBRA 4GKMA 4OWSA 4X59A 4N93A 4GTNA 4OWVA 1RF8B 1RRZA 2ELCA 4OWNA 5BYTA 1AZYA 1UOUA 4X5EA 4ZOFA 2TPTA 4IJ1A 1GXBA 2DSJA 4X46A 4X5CA 1KGZA 2WK6A 4HKMA 3QSAA 2GVQA 1ZVWA 1V8GA 3R88A 5C2LA 5C7SA 4GIUA 4OWQA 3TWPA 3H5QA 4MUOA 3UU1A 4YEKA 4OWOA 4YI7A 3R6CA 5EY3A 4GA4A 5BO3A 4X5DA 5BO2A 2BPQA 3QR9A 4N5VA 4N8QA 4OWMA 1BRWA 4EAFA 5C1RA 4F3FC 4GA6A 1O17A 2J0FA 4X5AA 4EADA
chains in the Genus database with same CATH topology
1OTPA 4OWUA 4ZTVA 4YYYA 1VQUA 4XR5A 4LHMA 4X5BA 1ZYKA 4X58A 3QS8A 4M0RA 3QQSA 1KHDA 5EP8A 2WK5A 4ZOKA 4ZOJA 5BNEA 1ZXYA 4GA5A 3GBRA 4GKMA 4OWSA 4X59A 4N93A 4GTNA 4OWVA 2ELCA 4OWNA 5BYTA 1AZYA 1UOUA 4X5EA 4ZOFA 2TPTA 4IJ1A 1GXBA 2DSJA 4X46A 4X5CA 1KGZA 2WK6A 4HKMA 3QSAA 2GVQA 1ZVWA 1V8GA 3R88A 5C2LA 5C7SA 4GIUA 4OWQA 3TWPA 3H5QA 4MUOA 3UU1A 4YEKA 4OWOA 4YI7A 3R6CA 5EY3A 4GA4A 5BO3A 4X5DA 5BO2A 2BPQA 3QR9A 4N5VA 4N8QA 4OWMA 1BRWA 4EAFA 5C1RA 4GA6A 1O17A 2J0FA 4X5AA 4EADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OTP A;  4OWU A;  4ZTV A;  4YYY A;  1VQU A;  4XR5 A;  4LHM A;  4X5B A;  1ZYK A;  4X58 A;  3QS8 A;  4M0R A;  3QQS A;  1KHD A;  5EP8 A;  2WK5 A;  4ZOK A;  4ZOJ A;  5BNE A;  1ZXY A;  4GA5 A;  3GBR A;  4GKM A;  4OWS A;  4X59 A;  4N93 A;  4GTN A;  4OWV A;  2ELC A;  4OWN A;  5BYT A;  1AZY A;  1UOU A;  4X5E A;  4ZOF A;  2TPT A;  4IJ1 A;  1GXB A;  2DSJ A;  4X46 A;  4X5C A;  1KGZ A;  2WK6 A;  4HKM A;  3QSA A;  2GVQ A;  1ZVW A;  1V8G A;  3R88 A;  5C2L A;  5C7S A;  4GIU A;  4OWQ A;  3TWP A;  3H5Q A;  4MUO A;  3UU1 A;  4YEK A;  4OWO A;  4YI7 A;  3R6C A;  5EY3 A;  4GA4 A;  5BO3 A;  4X5D A;  5BO2 A;  2BPQ A;  3QR9 A;  4N5V A;  4N8Q A;  4OWM A;  1BRW A;  4EAF A;  5C1R A;  4GA6 A;  1O17 A;  2J0F A;  4X5A A;  4EAD A; 
#chains in the Genus database with same CATH topology
 1OTP A;  4OWU A;  4ZTV A;  4YYY A;  1VQU A;  4XR5 A;  4LHM A;  4X5B A;  1ZYK A;  4X58 A;  3QS8 A;  4M0R A;  3QQS A;  1KHD A;  5EP8 A;  2WK5 A;  4ZOK A;  4ZOJ A;  5BNE A;  1ZXY A;  4GA5 A;  3GBR A;  4GKM A;  4OWS A;  4X59 A;  4N93 A;  4GTN A;  4OWV A;  1RF8 B;  1RRZ A;  2ELC A;  4OWN A;  5BYT A;  1AZY A;  1UOU A;  4X5E A;  4ZOF A;  2TPT A;  4IJ1 A;  1GXB A;  2DSJ A;  4X46 A;  4X5C A;  1KGZ A;  2WK6 A;  4HKM A;  3QSA A;  2GVQ A;  1ZVW A;  1V8G A;  3R88 A;  5C2L A;  5C7S A;  4GIU A;  4OWQ A;  3TWP A;  3H5Q A;  4MUO A;  3UU1 A;  4YEK A;  4OWO A;  4YI7 A;  3R6C A;  5EY3 A;  4GA4 A;  5BO3 A;  4X5D A;  5BO2 A;  2BPQ A;  3QR9 A;  4N5V A;  4N8Q A;  4OWM A;  1BRW A;  4EAF A;  5C1R A;  4F3F C;  4GA6 A;  1O17 A;  2J0F A;  4X5A A;  4EAD A; 
#chains in the Genus database with same CATH homology
 1OTP A;  4OWU A;  4ZTV A;  4YYY A;  1VQU A;  4XR5 A;  4LHM A;  4X5B A;  1ZYK A;  4X58 A;  3QS8 A;  4M0R A;  3QQS A;  1KHD A;  5EP8 A;  2WK5 A;  4ZOK A;  4ZOJ A;  5BNE A;  1ZXY A;  4GA5 A;  3GBR A;  4GKM A;  4OWS A;  4X59 A;  4N93 A;  4GTN A;  4OWV A;  2ELC A;  4OWN A;  5BYT A;  1AZY A;  1UOU A;  4X5E A;  4ZOF A;  2TPT A;  4IJ1 A;  1GXB A;  2DSJ A;  4X46 A;  4X5C A;  1KGZ A;  2WK6 A;  4HKM A;  3QSA A;  2GVQ A;  1ZVW A;  1V8G A;  3R88 A;  5C2L A;  5C7S A;  4GIU A;  4OWQ A;  3TWP A;  3H5Q A;  4MUO A;  3UU1 A;  4YEK A;  4OWO A;  4YI7 A;  3R6C A;  5EY3 A;  4GA4 A;  5BO3 A;  4X5D A;  5BO2 A;  2BPQ A;  3QR9 A;  4N5V A;  4N8Q A;  4OWM A;  1BRW A;  4EAF A;  5C1R A;  4GA6 A;  1O17 A;  2J0F A;  4X5A A;  4EAD A; 
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