1RF8B

Solution structure of the yeast translation initiation factor eif4e in complex with m7gdp and eif4gi residues 393 to 490
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
100
structure length
100
Chain Sequence
GSIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
pubmed doi rcsb
molecule keywords Eukaryotic translation initiation factor 4E
molecule tags Biosynthetic protein, translation
source organism Saccharomyces cerevisiae
total genus 12
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF12152 eIF_4G1 Eukaryotic translation initiation factor 4G1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.30 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 1rf8B01
1RF8B
chains in the Genus database with same CATH superfamily
1UOUA 2GVQA 1RRZA 2ELCA 2WK5A 2DSJA 2TPTA 5C1RA 1ZXYA 4X46A 4OWMA 1ZVWA 5C2LA 4IJ1A 4GIUA 1O17A 4EAFA 4X59A 4X5EA 4X5BA 4LHMA 4X5DA 1VQUA 4GA5A 4GTNA 1KHDA 1KGZA 4OWSA 1GXBA 3GBRA 5BO2A 4OWQA 4ZTVA 4N5VA 5EY3A 4F3FC 4ZOKA 5C7SA 2BPQA 4X58A 2J0FA 4X5AA 1ZYKA 5BNEA 1AZYA 4GA4A 3UU1A 3H5QA 4EADA 4MUOA 4ZOFA 4YEKA 4OWNA 5BYTA 3R88A 4OWUA 4HKMA 3QR9A 1V8GA 4GA6A 3QS8A 4X5CA 4XR5A 5EP8A 4OWOA 4N93A 4YYYA 4ZOJA 4M0RA 1OTPA 1RF8B 3QQSA 1BRWA 4OWVA 4N8QA 4GKMA 3QSAA 2WK6A 4YI7A 3R6CA 5BO3A 3TWPA
chains in the Genus database with same CATH topology
4F3FC 4GA6A 4GA5A 1RF8B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF8 B; 
#chains in the Genus database with same CATH topology
 1UOU A;  2GVQ A;  1RRZ A;  2ELC A;  2WK5 A;  2DSJ A;  2TPT A;  5C1R A;  1ZXY A;  4X46 A;  4OWM A;  1ZVW A;  5C2L A;  4IJ1 A;  4GIU A;  1O17 A;  4EAF A;  4X59 A;  4X5E A;  4X5B A;  4LHM A;  4X5D A;  1VQU A;  4GA5 A;  4GTN A;  1KHD A;  1KGZ A;  4OWS A;  1GXB A;  3GBR A;  5BO2 A;  4OWQ A;  4ZTV A;  4N5V A;  5EY3 A;  4F3F C;  4ZOK A;  5C7S A;  2BPQ A;  4X58 A;  2J0F A;  4X5A A;  1ZYK A;  5BNE A;  1AZY A;  4GA4 A;  3UU1 A;  3H5Q A;  4EAD A;  4MUO A;  4ZOF A;  4YEK A;  4OWN A;  5BYT A;  3R88 A;  4OWU A;  4HKM A;  3QR9 A;  1V8G A;  4GA6 A;  3QS8 A;  4X5C A;  4XR5 A;  5EP8 A;  4OWO A;  4N93 A;  4YYY A;  4ZOJ A;  4M0R A;  1OTP A;  1RF8 B;  3QQS A;  1BRW A;  4OWV A;  4N8Q A;  4GKM A;  3QSA A;  2WK6 A;  4YI7 A;  3R6C A;  5BO3 A;  3TWP A; 
#chains in the Genus database with same CATH homology
 4F3F C;  4GA6 A;  4GA5 A;  1RF8 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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