1RF8 | Genus

Total Genus 12

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	12
sequence length	100
structure length	100
Chain Sequence	GSIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 100 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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100 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. pubmed doi rcsb
molecule keywords	Eukaryotic translation initiation factor 4E
molecule tags	Biosynthetic protein, translation
source organism	Saccharomyces cerevisiae
total genus	12
structure length	100
sequence length	100
ec nomenclature
pdb deposition date	2003-11-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF12152	eIF_4G1	Eukaryotic translation initiation factor 4G1

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.970.30	Mainly Alpha	Up-down Bundle	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3	1rf8B01

1RF8B
chains in the Genus database with same CATH superfamily

4GTNA 4F3FC 2ELCA 4GA5A 5EY3A 1VQUA 4EAFA 4HKMA 3R88A 1OTPA 3GBRA 4GKMA 1RF8B 4OWQA 4IJ1A 2WK6A 3QR9A 4M0RA 5BNEA 1O17A 3R6CA 4XR5A 3TWPA 4MUOA 5C1RA 1BRWA 4OWSA 4X46A 3UU1A 1RRZA 1ZYKA 2J0FA 4ZTVA 5BYTA 4ZOFA 4GA4A 4YEKA 4N93A 4X58A 4YYYA 3QSAA 4OWOA 2BPQA 4YI7A 1V8GA 4X59A 3QS8A 4X5CA 4N8QA 5BO2A 1AZYA 1ZVWA 1GXBA 2DSJA 2GVQA 4X5AA 3QQSA 1KHDA 2TPTA 4ZOJA 4GA6A 2WK5A 1ZXYA 4GIUA 1UOUA 4OWNA 5C7SA 1KGZA 3H5QA 5C2LA 4N5VA 4LHMA 4OWMA 4ZOKA 4OWVA 5BO3A 4EADA 4OWUA 4X5BA 4X5DA 4X5EA 5EP8A
chains in the Genus database with same CATH topology

1RF8B 4GA6A 4GA5A 4F3FC
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1RF8 B; 
#chains in the Genus database with same CATH topology
 4GTN A;  4F3F C;  2ELC A;  4GA5 A;  5EY3 A;  1VQU A;  4EAF A;  4HKM A;  3R88 A;  1OTP A;  3GBR A;  4GKM A;  1RF8 B;  4OWQ A;  4IJ1 A;  2WK6 A;  3QR9 A;  4M0R A;  5BNE A;  1O17 A;  3R6C A;  4XR5 A;  3TWP A;  4MUO A;  5C1R A;  1BRW A;  4OWS A;  4X46 A;  3UU1 A;  1RRZ A;  1ZYK A;  2J0F A;  4ZTV A;  5BYT A;  4ZOF A;  4GA4 A;  4YEK A;  4N93 A;  4X58 A;  4YYY A;  3QSA A;  4OWO A;  2BPQ A;  4YI7 A;  1V8G A;  4X59 A;  3QS8 A;  4X5C A;  4N8Q A;  5BO2 A;  1AZY A;  1ZVW A;  1GXB A;  2DSJ A;  2GVQ A;  4X5A A;  3QQS A;  1KHD A;  2TPT A;  4ZOJ A;  4GA6 A;  2WK5 A;  1ZXY A;  4GIU A;  1UOU A;  4OWN A;  5C7S A;  1KGZ A;  3H5Q A;  5C2L A;  4N5V A;  4LHM A;  4OWM A;  4ZOK A;  4OWV A;  5BO3 A;  4EAD A;  4OWU A;  4X5B A;  4X5D A;  4X5E A;  5EP8 A; 
#chains in the Genus database with same CATH homology
 1RF8 B;  4GA6 A;  4GA5 A;  4F3F C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1RF8B

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations