1RF8B

Solution structure of the yeast translation initiation factor eif4e in complex with m7gdp and eif4gi residues 393 to 490
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
100
structure length
100
Chain Sequence
GSIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
pubmed doi rcsb
molecule tags Biosynthetic protein, translation
source organism Saccharomyces cerevisiae
molecule keywords Eukaryotic translation initiation factor 4E
total genus 12
structure length 100
sequence length 100
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF12152 eIF_4G1 Eukaryotic translation initiation factor 4G1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.30 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 1rf8B01
1RF8B
chains in the Genus database with same CATH superfamily
4F3FC 4ZOJA 5BO2A 4GA6A 3TWPA 1BRWA 4EAFA 4X5BA 4M0RA 4EADA 1ZVWA 3H5QA 2ELCA 4IJ1A 4OWMA 1O17A 4X5EA 1VQUA 4OWVA 4OWUA 4OWSA 4X5CA 3R88A 1RF8B 4X5AA 1AZYA 5C1RA 4ZOFA 3UU1A 4YI7A 5BO3A 3R6CA 1KHDA 4GKMA 4N93A 4X58A 4OWOA 1GXBA 1ZXYA 2J0FA 3GBRA 4GA5A 2DSJA 5C7SA 2GVQA 4OWQA 4XR5A 1ZYKA 3QR9A 1V8GA 4N8QA 1KGZA 3QSAA 4YYYA 2BPQA 2WK5A 5C2LA 4X59A 5EY3A 1RRZA 4HKMA 3QQSA 4GA4A 4X5DA 5EP8A 4ZOKA 1OTPA 1UOUA 4GIUA 4ZTVA 4N5VA 2WK6A 3QS8A 5BYTA 4MUOA 2TPTA 4OWNA 4LHMA 5BNEA 4X46A 4YEKA 4GTNA
chains in the Genus database with same CATH topology
1RF8B 4GA6A 4F3FC 4GA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF8 B; 
#chains in the Genus database with same CATH topology
 4F3F C;  4ZOJ A;  5BO2 A;  4GA6 A;  3TWP A;  1BRW A;  4EAF A;  4X5B A;  4M0R A;  4EAD A;  1ZVW A;  3H5Q A;  2ELC A;  4IJ1 A;  4OWM A;  1O17 A;  4X5E A;  1VQU A;  4OWV A;  4OWU A;  4OWS A;  4X5C A;  3R88 A;  1RF8 B;  4X5A A;  1AZY A;  5C1R A;  4ZOF A;  3UU1 A;  4YI7 A;  5BO3 A;  3R6C A;  1KHD A;  4GKM A;  4N93 A;  4X58 A;  4OWO A;  1GXB A;  1ZXY A;  2J0F A;  3GBR A;  4GA5 A;  2DSJ A;  5C7S A;  2GVQ A;  4OWQ A;  4XR5 A;  1ZYK A;  3QR9 A;  1V8G A;  4N8Q A;  1KGZ A;  3QSA A;  4YYY A;  2BPQ A;  2WK5 A;  5C2L A;  4X59 A;  5EY3 A;  1RRZ A;  4HKM A;  3QQS A;  4GA4 A;  4X5D A;  5EP8 A;  4ZOK A;  1OTP A;  1UOU A;  4GIU A;  4ZTV A;  4N5V A;  2WK6 A;  3QS8 A;  5BYT A;  4MUO A;  2TPT A;  4OWN A;  4LHM A;  5BNE A;  4X46 A;  4YEK A;  4GTN A; 
#chains in the Genus database with same CATH homology
 1RF8 B;  4GA6 A;  4F3F C;  4GA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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