1ZVWA

The crystal structure of trpd (rv2192c) from mycobacterium tuberculosis in complex with prpp and magnesium
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
346
structure length
346
Chain Sequence
PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Anthranilate phosphoribosyltransferase
total genus 107
structure length 346
sequence length 346
chains with identical sequence B
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2005-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 1zvwA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 1zvwA02
1ZVWA 4GA5A 4MUOA 4ZOKA 5C7SA 4HKMA 3R6CA 4X46A 4X59A 4OWNA 4OWSA 1OTPA 5EP8A 2BPQA 4GA6A 5C1RA 2DSJA 5BYTA 2WK5A 4ZTVA 3GBRA 5BO3A 5EY3A 4OWQA 3QQSA 4N93A 4X58A 3TWPA 1GXBA 1UOUA 4X5DA 4OWOA 2GVQA 1BRWA 3R88A 3H5QA 3QS8A 2ELCA 4IJ1A 2WK6A 1VQUA 5BO2A 4LHMA 4OWVA 4YI7A 3UU1A 1ZXYA 5BNEA 4XR5A 4OWMA 4GA4A 4GKMA 1ZYKA 4GIUA 4N8QA 1V8GA 5C2LA 4OWUA 4X5AA 4ZOFA 2TPTA 4N5VA 4EADA 4GTNA 4YEKA 4X5CA 4M0RA 4X5EA 3QSAA 1KGZA 4X5BA 1AZYA 3QR9A 1KHDA 4EAFA 4YYYA 1O17A 4ZOJA 2J0FA
chains in the Genus database with same CATH superfamily
1ZVWA 4GA5A 4MUOA 4ZOKA 5C7SA 4HKMA 3R6CA 4X46A 4X59A 4OWNA 4OWSA 1OTPA 5EP8A 2BPQA 4GA6A 5C1RA 2DSJA 5BYTA 2WK5A 4ZTVA 1RF8B 3GBRA 5BO3A 5EY3A 4OWQA 1RRZA 3QQSA 4N93A 4X58A 3TWPA 1GXBA 1UOUA 4X5DA 4OWOA 2GVQA 1BRWA 3R88A 3H5QA 3QS8A 2ELCA 4IJ1A 2WK6A 1VQUA 5BO2A 4LHMA 4OWVA 4F3FC 4YI7A 3UU1A 1ZXYA 5BNEA 4XR5A 4OWMA 4GA4A 4GKMA 1ZYKA 4GIUA 4N8QA 1V8GA 5C2LA 4OWUA 4X5AA 4ZOFA 2TPTA 4N5VA 4EADA 4GTNA 4YEKA 4X5CA 4M0RA 4X5EA 3QSAA 1KGZA 4X5BA 1AZYA 3QR9A 1KHDA 4EAFA 4YYYA 1O17A 4ZOJA 2J0FA
chains in the Genus database with same CATH topology
1ZVWA 4GA5A 4MUOA 4ZOKA 5C7SA 4HKMA 3R6CA 4X46A 4X59A 4OWNA 4OWSA 1OTPA 5EP8A 2BPQA 4GA6A 5C1RA 2DSJA 5BYTA 2WK5A 4ZTVA 3GBRA 5BO3A 5EY3A 4OWQA 3QQSA 4N93A 4X58A 3TWPA 1GXBA 1UOUA 4X5DA 4OWOA 2GVQA 1BRWA 3R88A 3H5QA 3QS8A 2ELCA 4IJ1A 2WK6A 1VQUA 5BO2A 4LHMA 4OWVA 4YI7A 3UU1A 1ZXYA 5BNEA 4XR5A 4OWMA 4GA4A 4GKMA 1ZYKA 4GIUA 4N8QA 1V8GA 5C2LA 4OWUA 4X5AA 4ZOFA 2TPTA 4N5VA 4EADA 4GTNA 4YEKA 4X5CA 4M0RA 4X5EA 3QSAA 1KGZA 4X5BA 1AZYA 3QR9A 1KHDA 4EAFA 4YYYA 1O17A 4ZOJA 2J0FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZVW A;  4GA5 A;  4MUO A;  4ZOK A;  5C7S A;  4HKM A;  3R6C A;  4X46 A;  4X59 A;  4OWN A;  4OWS A;  1OTP A;  5EP8 A;  2BPQ A;  4GA6 A;  5C1R A;  2DSJ A;  5BYT A;  2WK5 A;  4ZTV A;  3GBR A;  5BO3 A;  5EY3 A;  4OWQ A;  3QQS A;  4N93 A;  4X58 A;  3TWP A;  1GXB A;  1UOU A;  4X5D A;  4OWO A;  2GVQ A;  1BRW A;  3R88 A;  3H5Q A;  3QS8 A;  2ELC A;  4IJ1 A;  2WK6 A;  1VQU A;  5BO2 A;  4LHM A;  4OWV A;  4YI7 A;  3UU1 A;  1ZXY A;  5BNE A;  4XR5 A;  4OWM A;  4GA4 A;  4GKM A;  1ZYK A;  4GIU A;  4N8Q A;  1V8G A;  5C2L A;  4OWU A;  4X5A A;  4ZOF A;  2TPT A;  4N5V A;  4EAD A;  4GTN A;  4YEK A;  4X5C A;  4M0R A;  4X5E A;  3QSA A;  1KGZ A;  4X5B A;  1AZY A;  3QR9 A;  1KHD A;  4EAF A;  4YYY A;  1O17 A;  4ZOJ A;  2J0F A; 
#chains in the Genus database with same CATH topology
 1ZVW A;  4GA5 A;  4MUO A;  4ZOK A;  5C7S A;  4HKM A;  3R6C A;  4X46 A;  4X59 A;  4OWN A;  4OWS A;  1OTP A;  5EP8 A;  2BPQ A;  4GA6 A;  5C1R A;  2DSJ A;  5BYT A;  2WK5 A;  4ZTV A;  1RF8 B;  3GBR A;  5BO3 A;  5EY3 A;  4OWQ A;  1RRZ A;  3QQS A;  4N93 A;  4X58 A;  3TWP A;  1GXB A;  1UOU A;  4X5D A;  4OWO A;  2GVQ A;  1BRW A;  3R88 A;  3H5Q A;  3QS8 A;  2ELC A;  4IJ1 A;  2WK6 A;  1VQU A;  5BO2 A;  4LHM A;  4OWV A;  4F3F C;  4YI7 A;  3UU1 A;  1ZXY A;  5BNE A;  4XR5 A;  4OWM A;  4GA4 A;  4GKM A;  1ZYK A;  4GIU A;  4N8Q A;  1V8G A;  5C2L A;  4OWU A;  4X5A A;  4ZOF A;  2TPT A;  4N5V A;  4EAD A;  4GTN A;  4YEK A;  4X5C A;  4M0R A;  4X5E A;  3QSA A;  1KGZ A;  4X5B A;  1AZY A;  3QR9 A;  1KHD A;  4EAF A;  4YYY A;  1O17 A;  4ZOJ A;  2J0F A; 
#chains in the Genus database with same CATH homology
 1ZVW A;  4GA5 A;  4MUO A;  4ZOK A;  5C7S A;  4HKM A;  3R6C A;  4X46 A;  4X59 A;  4OWN A;  4OWS A;  1OTP A;  5EP8 A;  2BPQ A;  4GA6 A;  5C1R A;  2DSJ A;  5BYT A;  2WK5 A;  4ZTV A;  3GBR A;  5BO3 A;  5EY3 A;  4OWQ A;  3QQS A;  4N93 A;  4X58 A;  3TWP A;  1GXB A;  1UOU A;  4X5D A;  4OWO A;  2GVQ A;  1BRW A;  3R88 A;  3H5Q A;  3QS8 A;  2ELC A;  4IJ1 A;  2WK6 A;  1VQU A;  5BO2 A;  4LHM A;  4OWV A;  4YI7 A;  3UU1 A;  1ZXY A;  5BNE A;  4XR5 A;  4OWM A;  4GA4 A;  4GKM A;  1ZYK A;  4GIU A;  4N8Q A;  1V8G A;  5C2L A;  4OWU A;  4X5A A;  4ZOF A;  2TPT A;  4N5V A;  4EAD A;  4GTN A;  4YEK A;  4X5C A;  4M0R A;  4X5E A;  3QSA A;  1KGZ A;  4X5B A;  1AZY A;  3QR9 A;  1KHD A;  4EAF A;  4YYY A;  1O17 A;  4ZOJ A;  2J0F A; 
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