1ZVWA

The crystal structure of trpd (rv2192c) from mycobacterium tuberculosis in complex with prpp and magnesium
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
346
structure length
346
Chain Sequence
PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Anthranilate phosphoribosyltransferase
total genus 107
structure length 346
sequence length 346
chains with identical sequence B
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2005-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 1zvwA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 1zvwA02
4N5VA 5C1RA 1AZYA 4X59A 4X5CA 4ZOKA 3R88A 4MUOA 5C2LA 4GKMA 5BO3A 1VQUA 1GXBA 5EY3A 2WK5A 5BYTA 1KGZA 3QSAA 4OWUA 1UOUA 4YEKA 4GTNA 3R6CA 4HKMA 5C7SA 2ELCA 4OWNA 4X46A 1ZYKA 3H5QA 3QQSA 4M0RA 4IJ1A 2WK6A 1V8GA 4ZOFA 2DSJA 4ZOJA 4XR5A 4OWSA 4N93A 4OWMA 1KHDA 3QS8A 1OTPA 4X5AA 1BRWA 1ZXYA 4OWVA 4X58A 3TWPA 4GA4A 1O17A 4EAFA 4OWOA 2GVQA 4EADA 4YYYA 4ZTVA 5BO2A 4GA6A 3UU1A 5BNEA 4GIUA 2BPQA 4X5BA 5EP8A 4LHMA 4X5EA 3QR9A 3GBRA 4YI7A 4N8QA 4GA5A 2J0FA 4X5DA 1ZVWA 2TPTA 4OWQA
chains in the Genus database with same CATH superfamily
4N5VA 5C1RA 1AZYA 4X59A 4X5CA 4ZOKA 3R88A 4MUOA 5C2LA 4GKMA 5BO3A 1VQUA 1RF8B 1GXBA 5EY3A 2WK5A 5BYTA 1KGZA 3QSAA 4OWUA 1UOUA 4YEKA 4GTNA 3R6CA 4HKMA 5C7SA 2ELCA 4OWNA 4X46A 1ZYKA 3H5QA 3QQSA 4M0RA 4IJ1A 2WK6A 1V8GA 4ZOFA 2DSJA 4ZOJA 4XR5A 4OWSA 4N93A 4OWMA 1KHDA 3QS8A 1OTPA 4X5AA 1BRWA 1ZXYA 4OWVA 4X58A 3TWPA 4GA4A 1O17A 4EAFA 4OWOA 2GVQA 4EADA 4YYYA 4ZTVA 5BO2A 1RRZA 4GA6A 4F3FC 3UU1A 5BNEA 4GIUA 2BPQA 4X5BA 5EP8A 4LHMA 4X5EA 3QR9A 3GBRA 4YI7A 4GA5A 4N8QA 2J0FA 4X5DA 1ZVWA 2TPTA 4OWQA
chains in the Genus database with same CATH topology
4N5VA 5C1RA 1AZYA 4X59A 4X5CA 4ZOKA 3R88A 4MUOA 5C2LA 4GKMA 5BO3A 1VQUA 1GXBA 5EY3A 2WK5A 5BYTA 1KGZA 3QSAA 4OWUA 1UOUA 4YEKA 4GTNA 3R6CA 4HKMA 5C7SA 2ELCA 4OWNA 4X46A 1ZYKA 3H5QA 3QQSA 4M0RA 4IJ1A 2WK6A 1V8GA 4ZOFA 2DSJA 4ZOJA 4XR5A 4OWSA 4N93A 4OWMA 1KHDA 3QS8A 1OTPA 4X5AA 1BRWA 1ZXYA 4OWVA 4X58A 3TWPA 4GA4A 1O17A 4EAFA 4OWOA 2GVQA 4EADA 4YYYA 4ZTVA 5BO2A 4GA6A 3UU1A 5BNEA 4GIUA 2BPQA 4X5BA 5EP8A 4LHMA 4X5EA 3QR9A 3GBRA 4YI7A 4N8QA 4GA5A 2J0FA 4X5DA 1ZVWA 2TPTA 4OWQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N5V A;  5C1R A;  1AZY A;  4X59 A;  4X5C A;  4ZOK A;  3R88 A;  4MUO A;  5C2L A;  4GKM A;  5BO3 A;  1VQU A;  1GXB A;  5EY3 A;  2WK5 A;  5BYT A;  1KGZ A;  3QSA A;  4OWU A;  1UOU A;  4YEK A;  4GTN A;  3R6C A;  4HKM A;  5C7S A;  2ELC A;  4OWN A;  4X46 A;  1ZYK A;  3H5Q A;  3QQS A;  4M0R A;  4IJ1 A;  2WK6 A;  1V8G A;  4ZOF A;  2DSJ A;  4ZOJ A;  4XR5 A;  4OWS A;  4N93 A;  4OWM A;  1KHD A;  3QS8 A;  1OTP A;  4X5A A;  1BRW A;  1ZXY A;  4OWV A;  4X58 A;  3TWP A;  4GA4 A;  1O17 A;  4EAF A;  4OWO A;  2GVQ A;  4EAD A;  4YYY A;  4ZTV A;  5BO2 A;  4GA6 A;  3UU1 A;  5BNE A;  4GIU A;  2BPQ A;  4X5B A;  5EP8 A;  4LHM A;  4X5E A;  3QR9 A;  3GBR A;  4YI7 A;  4N8Q A;  4GA5 A;  2J0F A;  4X5D A;  1ZVW A;  2TPT A;  4OWQ A; 
#chains in the Genus database with same CATH topology
 4N5V A;  5C1R A;  1AZY A;  4X59 A;  4X5C A;  4ZOK A;  3R88 A;  4MUO A;  5C2L A;  4GKM A;  5BO3 A;  1VQU A;  1RF8 B;  1GXB A;  5EY3 A;  2WK5 A;  5BYT A;  1KGZ A;  3QSA A;  4OWU A;  1UOU A;  4YEK A;  4GTN A;  3R6C A;  4HKM A;  5C7S A;  2ELC A;  4OWN A;  4X46 A;  1ZYK A;  3H5Q A;  3QQS A;  4M0R A;  4IJ1 A;  2WK6 A;  1V8G A;  4ZOF A;  2DSJ A;  4ZOJ A;  4XR5 A;  4OWS A;  4N93 A;  4OWM A;  1KHD A;  3QS8 A;  1OTP A;  4X5A A;  1BRW A;  1ZXY A;  4OWV A;  4X58 A;  3TWP A;  4GA4 A;  1O17 A;  4EAF A;  4OWO A;  2GVQ A;  4EAD A;  4YYY A;  4ZTV A;  5BO2 A;  1RRZ A;  4GA6 A;  4F3F C;  3UU1 A;  5BNE A;  4GIU A;  2BPQ A;  4X5B A;  5EP8 A;  4LHM A;  4X5E A;  3QR9 A;  3GBR A;  4YI7 A;  4GA5 A;  4N8Q A;  2J0F A;  4X5D A;  1ZVW A;  2TPT A;  4OWQ A; 
#chains in the Genus database with same CATH homology
 4N5V A;  5C1R A;  1AZY A;  4X59 A;  4X5C A;  4ZOK A;  3R88 A;  4MUO A;  5C2L A;  4GKM A;  5BO3 A;  1VQU A;  1GXB A;  5EY3 A;  2WK5 A;  5BYT A;  1KGZ A;  3QSA A;  4OWU A;  1UOU A;  4YEK A;  4GTN A;  3R6C A;  4HKM A;  5C7S A;  2ELC A;  4OWN A;  4X46 A;  1ZYK A;  3H5Q A;  3QQS A;  4M0R A;  4IJ1 A;  2WK6 A;  1V8G A;  4ZOF A;  2DSJ A;  4ZOJ A;  4XR5 A;  4OWS A;  4N93 A;  4OWM A;  1KHD A;  3QS8 A;  1OTP A;  4X5A A;  1BRW A;  1ZXY A;  4OWV A;  4X58 A;  3TWP A;  4GA4 A;  1O17 A;  4EAF A;  4OWO A;  2GVQ A;  4EAD A;  4YYY A;  4ZTV A;  5BO2 A;  4GA6 A;  3UU1 A;  5BNE A;  4GIU A;  2BPQ A;  4X5B A;  5EP8 A;  4LHM A;  4X5E A;  3QR9 A;  3GBR A;  4YI7 A;  4N8Q A;  4GA5 A;  2J0F A;  4X5D A;  1ZVW A;  2TPT A;  4OWQ A; 
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