3E6PL

Crystal structure of human meizothrombin desf1
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
150
structure length
150
Chain Sequence
QCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Na(+) binding to meizothrombin desF1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Prothrombin
total genus 19
structure length 150
sequence length 150
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2008-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00051 Kringle Kringle domain
L PF09396 Thrombin_light Thrombin light chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 3e6pL01
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3e6pL02
3BT1A 3HN4A 4O03A 5CT2A 5COEA 1CEBA 5CS5A 2DOHX 1HPKA 1KIVA 2DOIA 1PKRA 1A0HA 2QJ4A 2PV9A 2PGQA 3BT2A 4RKOA 2PF2A 3K65A 3B9FL 2ODYA 1PMKA 3MKPA 2HPQP 5CS3A 3LAQA 1AVGL 2B5TA 5CT1A 2PK4A 2QJ2A 1TPKA 1TQ7A 3HKIA 4DY7A 5CSQA 3LU9A 3EDXA 3SP8A 1GMNA 1Z8JA 4CIKA 1HPJA 1B2IA 4HZHA 4BV7A 5HPGA 3NXPA 4BV5A 4NZQA 3BEFA 1JOUA 3E6PL 4BVCA 1TBRJ 1PMLA 1NL2A 1CEAA 1BHTA 1TB6L 2PF1A 3HK6A 5CS1A 1NL1A 2I9BA 2KJ4A 4DURA 2SPTA 2L0SA 4IUAA 2HPPP 1PK4A 1PK2A 2FD6A 4BVWA 1URKA 1NK1A 1GP9A 2KNFA 2K51A 1KRNA 4A5TS 1I5KA 2PUXA 1JMOL 3U73A 5CP9A 4BVVA 3KIVA 4KIVA 3GISA 1KI0A 1TBQJ 1I71A 4BVDA 2I9AA 3BEIA 2K4RA 5CT3A 1KDUA 5CS9A 1GMOA 2FEBA 4D3CA 1JFNA 2A1DA
chains in the Genus database with same CATH superfamily
3BT1A 3HN4A 4O03A 5CT2A 5COEA 1CEBA 5CS5A 2DOHX 1HPKA 1KIVA 2DOIA 1PKRA 1A0HA 2QJ4A 2PV9A 2PGQA 3BT2A 4RKOA 2PF2A 3K65A 3B9FL 2ODYA 1PMKA 3MKPA 2HPQP 5CS3A 3LAQA 1AVGL 2B5TA 5CT1A 2PK4A 2QJ2A 1TPKA 1TQ7A 3HKIA 4DY7A 5CSQA 3LU9A 3EDXA 3SP8A 1GMNA 1Z8JA 4CIKA 1HPJA 1B2IA 4HZHA 4BV7A 5HPGA 3NXPA 4BV5A 4NZQA 3BEFA 1JOUA 3E6PL 4BVCA 1TBRJ 1PMLA 1NL2A 1CEAA 1BHTA 1TB6L 2PF1A 3HK6A 5CS1A 1NL1A 2I9BA 2KJ4A 4DURA 2SPTA 2L0SA 4IUAA 2HPPP 1PK4A 1PK2A 2FD6A 4BVWA 1URKA 1NK1A 1GP9A 2KNFA 2K51A 1KRNA 4A5TS 1I5KA 2PUXA 1JMOL 3U73A 5CP9A 4BVVA 3KIVA 4KIVA 3GISA 1KI0A 1TBQJ 1I71A 4BVDA 2I9AA 3BEIA 2K4RA 5CT3A 1KDUA 5CS9A 1GMOA 2FEBA 4D3CA 1JFNA 2A1DA
chains in the Genus database with same CATH topology
3BT1A 3HN4A 4O03A 5CT2A 5COEA 1CEBA 5CS5A 2DOHX 1HPKA 1KIVA 2DOIA 1PKRA 1A0HA 2QJ4A 2PV9A 2PGQA 3BT2A 4RKOA 2PF2A 3K65A 3B9FL 2ODYA 1PMKA 3MKPA 2HPQP 5CS3A 3LAQA 1AVGL 2B5TA 5CT1A 2PK4A 2QJ2A 1TPKA 1TQ7A 3HKIA 4DY7A 5CSQA 3LU9A 3EDXA 3SP8A 1GMNA 1Z8JA 4CIKA 1HPJA 1B2IA 4HZHA 4BV7A 5HPGA 3NXPA 4BV5A 4NZQA 3BEFA 1JOUA 3E6PL 4BVCA 1TBRJ 1PMLA 1NL2A 1CEAA 1BHTA 1TB6L 2PF1A 3HK6A 5CS1A 1NL1A 2I9BA 2KJ4A 4DURA 2SPTA 2L0SA 4IUAA 2HPPP 1PK4A 1PK2A 2FD6A 4BVWA 1URKA 1NK1A 1GP9A 2KNFA 2K51A 1KRNA 4A5TS 1I5KA 2PUXA 1JMOL 3U73A 5CP9A 4BVVA 3KIVA 4KIVA 3GISA 1KI0A 1TBQJ 1I71A 4BVDA 2I9AA 3BEIA 2K4RA 5CT3A 1KDUA 5CS9A 1GMOA 2FEBA 4D3CA 1JFNA 2A1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BT1 A;  3HN4 A;  4O03 A;  5CT2 A;  5COE A;  1CEB A;  5CS5 A;  2DOH X;  1HPK A;  1KIV A;  2DOI A;  1PKR A;  1A0H A;  2QJ4 A;  2PV9 A;  2PGQ A;  3BT2 A;  4RKO A;  2PF2 A;  3K65 A;  3B9F L;  2ODY A;  1PMK A;  3MKP A;  2HPQ P;  5CS3 A;  3LAQ A;  1AVG L;  2B5T A;  5CT1 A;  2PK4 A;  2QJ2 A;  1TPK A;  1TQ7 A;  3HKI A;  4DY7 A;  5CSQ A;  3LU9 A;  3EDX A;  3SP8 A;  1GMN A;  1Z8J A;  4CIK A;  1HPJ A;  1B2I A;  4HZH A;  4BV7 A;  5HPG A;  3NXP A;  4BV5 A;  4NZQ A;  3BEF A;  1JOU A;  3E6P L;  4BVC A;  1TBR J;  1PML A;  1NL2 A;  1CEA A;  1BHT A;  1TB6 L;  2PF1 A;  3HK6 A;  5CS1 A;  1NL1 A;  2I9B A;  2KJ4 A;  4DUR A;  2SPT A;  2L0S A;  4IUA A;  2HPP P;  1PK4 A;  1PK2 A;  2FD6 A;  4BVW A;  1URK A;  1NK1 A;  1GP9 A;  2KNF A;  2K51 A;  1KRN A;  4A5T S;  1I5K A;  2PUX A;  1JMO L;  3U73 A;  5CP9 A;  4BVV A;  3KIV A;  4KIV A;  3GIS A;  1KI0 A;  1TBQ J;  1I71 A;  4BVD A;  2I9A A;  3BEI A;  2K4R A;  5CT3 A;  1KDU A;  5CS9 A;  1GMO A;  2FEB A;  4D3C A;  1JFN A;  2A1D A; 
#chains in the Genus database with same CATH topology
 3BT1 A;  3HN4 A;  4O03 A;  5CT2 A;  5COE A;  1CEB A;  5CS5 A;  2DOH X;  1HPK A;  1KIV A;  2DOI A;  1PKR A;  1A0H A;  2QJ4 A;  2PV9 A;  2PGQ A;  3BT2 A;  4RKO A;  2PF2 A;  3K65 A;  3B9F L;  2ODY A;  1PMK A;  3MKP A;  2HPQ P;  5CS3 A;  3LAQ A;  1AVG L;  2B5T A;  5CT1 A;  2PK4 A;  2QJ2 A;  1TPK A;  1TQ7 A;  3HKI A;  4DY7 A;  5CSQ A;  3LU9 A;  3EDX A;  3SP8 A;  1GMN A;  1Z8J A;  4CIK A;  1HPJ A;  1B2I A;  4HZH A;  4BV7 A;  5HPG A;  3NXP A;  4BV5 A;  4NZQ A;  3BEF A;  1JOU A;  3E6P L;  4BVC A;  1TBR J;  1PML A;  1NL2 A;  1CEA A;  1BHT A;  1TB6 L;  2PF1 A;  3HK6 A;  5CS1 A;  1NL1 A;  2I9B A;  2KJ4 A;  4DUR A;  2SPT A;  2L0S A;  4IUA A;  2HPP P;  1PK4 A;  1PK2 A;  2FD6 A;  4BVW A;  1URK A;  1NK1 A;  1GP9 A;  2KNF A;  2K51 A;  1KRN A;  4A5T S;  1I5K A;  2PUX A;  1JMO L;  3U73 A;  5CP9 A;  4BVV A;  3KIV A;  4KIV A;  3GIS A;  1KI0 A;  1TBQ J;  1I71 A;  4BVD A;  2I9A A;  3BEI A;  2K4R A;  5CT3 A;  1KDU A;  5CS9 A;  1GMO A;  2FEB A;  4D3C A;  1JFN A;  2A1D A; 
#chains in the Genus database with same CATH homology
 3BT1 A;  3HN4 A;  4O03 A;  5CT2 A;  5COE A;  1CEB A;  5CS5 A;  2DOH X;  1HPK A;  1KIV A;  2DOI A;  1PKR A;  1A0H A;  2QJ4 A;  2PV9 A;  2PGQ A;  3BT2 A;  4RKO A;  2PF2 A;  3K65 A;  3B9F L;  2ODY A;  1PMK A;  3MKP A;  2HPQ P;  5CS3 A;  3LAQ A;  1AVG L;  2B5T A;  5CT1 A;  2PK4 A;  2QJ2 A;  1TPK A;  1TQ7 A;  3HKI A;  4DY7 A;  5CSQ A;  3LU9 A;  3EDX A;  3SP8 A;  1GMN A;  1Z8J A;  4CIK A;  1HPJ A;  1B2I A;  4HZH A;  4BV7 A;  5HPG A;  3NXP A;  4BV5 A;  4NZQ A;  3BEF A;  1JOU A;  3E6P L;  4BVC A;  1TBR J;  1PML A;  1NL2 A;  1CEA A;  1BHT A;  1TB6 L;  2PF1 A;  3HK6 A;  5CS1 A;  1NL1 A;  2I9B A;  2KJ4 A;  4DUR A;  2SPT A;  2L0S A;  4IUA A;  2HPP P;  1PK4 A;  1PK2 A;  2FD6 A;  4BVW A;  1URK A;  1NK1 A;  1GP9 A;  2KNF A;  2K51 A;  1KRN A;  4A5T S;  1I5K A;  2PUX A;  1JMO L;  3U73 A;  5CP9 A;  4BVV A;  3KIV A;  4KIV A;  3GIS A;  1KI0 A;  1TBQ J;  1I71 A;  4BVD A;  2I9A A;  3BEI A;  2K4R A;  5CT3 A;  1KDU A;  5CS9 A;  1GMO A;  2FEB A;  4D3C A;  1JFN A;  2A1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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