3E6PL

Crystal structure of human meizothrombin desf1
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
150
structure length
150
Chain Sequence
QCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Na(+) binding to meizothrombin desF1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Prothrombin
total genus 19
structure length 150
sequence length 150
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2008-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00051 Kringle Kringle domain
L PF09396 Thrombin_light Thrombin light chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 3e6pL01
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3e6pL02
1PK2A 3BEIA 2A1DA 3MKPA 4A5TS 3BEFA 4D3CA 2KJ4A 2L0SA 3K65A 1KIVA 1B2IA 4BV7A 2DOHX 5CS3A 4DURA 2HPPP 4DY7A 1NK1A 3U73A 1KRNA 2PF2A 1Z8JA 4IUAA 3LAQA 1GMNA 1JFNA 1TBQJ 2FD6A 1I71A 1CEAA 1JMOL 4KIVA 1TPKA 3HK6A 1PK4A 1HPJA 4O03A 3NXPA 2PGQA 5CSQA 2KNFA 2B5TA 1KI0A 5CS1A 2K4RA 5CT3A 3BT2A 1AVGL 2DOIA 5CS5A 1TBRJ 3EDXA 1JOUA 1TB6L 2I9BA 5CT1A 1PKRA 4NZQA 3HN4A 1PMKA 2I9AA 3LU9A 1GMOA 1PMLA 4RKOA 2PF1A 3B9FL 3GISA 1A0HA 4BVWA 1I5KA 1BHTA 3HKIA 2HPQP 3KIVA 2SPTA 2ODYA 1URKA 5COEA 2PV9A 5CS9A 1GP9A 4BVVA 4CIKA 1CEBA 5CP9A 2QJ2A 4BVCA 4HZHA 5CT2A 3E6PL 4BV5A 3SP8A 2PK4A 4BVDA 2FEBA 5HPGA 2K51A 1KDUA 1NL1A 1TQ7A 2QJ4A 3BT1A 2PUXA 1HPKA 1NL2A
chains in the Genus database with same CATH superfamily
1PK2A 3BEIA 2A1DA 3MKPA 4A5TS 3BEFA 4D3CA 2KJ4A 2L0SA 3K65A 1KIVA 1B2IA 4BV7A 2DOHX 5CS3A 4DURA 2HPPP 4DY7A 1NK1A 3U73A 1KRNA 2PF2A 1Z8JA 4IUAA 3LAQA 1GMNA 1JFNA 1TBQJ 2FD6A 1I71A 1CEAA 1JMOL 4KIVA 1TPKA 3HK6A 1PK4A 1HPJA 4O03A 3NXPA 2PGQA 5CSQA 2KNFA 2B5TA 1KI0A 5CS1A 2K4RA 5CT3A 3BT2A 1AVGL 2DOIA 5CS5A 1TBRJ 3EDXA 1JOUA 1TB6L 2I9BA 5CT1A 1PKRA 4NZQA 3HN4A 1PMKA 2I9AA 3LU9A 1GMOA 1PMLA 4RKOA 2PF1A 3B9FL 3GISA 1A0HA 4BVWA 1I5KA 1BHTA 3HKIA 2HPQP 3KIVA 2SPTA 2ODYA 1URKA 5COEA 2PV9A 5CS9A 1GP9A 4BVVA 4CIKA 1CEBA 5CP9A 2QJ2A 4BVCA 4HZHA 5CT2A 3E6PL 4BV5A 3SP8A 2PK4A 4BVDA 2FEBA 5HPGA 2K51A 1KDUA 1NL1A 1TQ7A 2QJ4A 3BT1A 2PUXA 1HPKA 1NL2A
chains in the Genus database with same CATH topology
1PK2A 3BEIA 2A1DA 3MKPA 4A5TS 3BEFA 4D3CA 2KJ4A 2L0SA 3K65A 1KIVA 1B2IA 4BV7A 2DOHX 5CS3A 4DURA 2HPPP 4DY7A 1NK1A 3U73A 1KRNA 2PF2A 1Z8JA 4IUAA 3LAQA 1GMNA 1JFNA 1TBQJ 2FD6A 1I71A 1CEAA 1JMOL 4KIVA 1TPKA 3HK6A 1PK4A 1HPJA 4O03A 3NXPA 2PGQA 5CSQA 2KNFA 2B5TA 1KI0A 5CS1A 2K4RA 5CT3A 3BT2A 1AVGL 2DOIA 5CS5A 1TBRJ 3EDXA 1JOUA 1TB6L 2I9BA 5CT1A 1PKRA 4NZQA 3HN4A 1PMKA 2I9AA 3LU9A 1GMOA 1PMLA 4RKOA 2PF1A 3B9FL 3GISA 1A0HA 4BVWA 1I5KA 1BHTA 3HKIA 2HPQP 3KIVA 2SPTA 2ODYA 1URKA 5COEA 2PV9A 5CS9A 1GP9A 4BVVA 4CIKA 1CEBA 5CP9A 2QJ2A 4BVCA 4HZHA 5CT2A 3E6PL 4BV5A 3SP8A 2PK4A 4BVDA 2FEBA 5HPGA 2K51A 1KDUA 1NL1A 1TQ7A 2QJ4A 3BT1A 2PUXA 1HPKA 1NL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PK2 A;  3BEI A;  2A1D A;  3MKP A;  4A5T S;  3BEF A;  4D3C A;  2KJ4 A;  2L0S A;  3K65 A;  1KIV A;  1B2I A;  4BV7 A;  2DOH X;  5CS3 A;  4DUR A;  2HPP P;  4DY7 A;  1NK1 A;  3U73 A;  1KRN A;  2PF2 A;  1Z8J A;  4IUA A;  3LAQ A;  1GMN A;  1JFN A;  1TBQ J;  2FD6 A;  1I71 A;  1CEA A;  1JMO L;  4KIV A;  1TPK A;  3HK6 A;  1PK4 A;  1HPJ A;  4O03 A;  3NXP A;  2PGQ A;  5CSQ A;  2KNF A;  2B5T A;  1KI0 A;  5CS1 A;  2K4R A;  5CT3 A;  3BT2 A;  1AVG L;  2DOI A;  5CS5 A;  1TBR J;  3EDX A;  1JOU A;  1TB6 L;  2I9B A;  5CT1 A;  1PKR A;  4NZQ A;  3HN4 A;  1PMK A;  2I9A A;  3LU9 A;  1GMO A;  1PML A;  4RKO A;  2PF1 A;  3B9F L;  3GIS A;  1A0H A;  4BVW A;  1I5K A;  1BHT A;  3HKI A;  2HPQ P;  3KIV A;  2SPT A;  2ODY A;  1URK A;  5COE A;  2PV9 A;  5CS9 A;  1GP9 A;  4BVV A;  4CIK A;  1CEB A;  5CP9 A;  2QJ2 A;  4BVC A;  4HZH A;  5CT2 A;  3E6P L;  4BV5 A;  3SP8 A;  2PK4 A;  4BVD A;  2FEB A;  5HPG A;  2K51 A;  1KDU A;  1NL1 A;  1TQ7 A;  2QJ4 A;  3BT1 A;  2PUX A;  1HPK A;  1NL2 A; 
#chains in the Genus database with same CATH topology
 1PK2 A;  3BEI A;  2A1D A;  3MKP A;  4A5T S;  3BEF A;  4D3C A;  2KJ4 A;  2L0S A;  3K65 A;  1KIV A;  1B2I A;  4BV7 A;  2DOH X;  5CS3 A;  4DUR A;  2HPP P;  4DY7 A;  1NK1 A;  3U73 A;  1KRN A;  2PF2 A;  1Z8J A;  4IUA A;  3LAQ A;  1GMN A;  1JFN A;  1TBQ J;  2FD6 A;  1I71 A;  1CEA A;  1JMO L;  4KIV A;  1TPK A;  3HK6 A;  1PK4 A;  1HPJ A;  4O03 A;  3NXP A;  2PGQ A;  5CSQ A;  2KNF A;  2B5T A;  1KI0 A;  5CS1 A;  2K4R A;  5CT3 A;  3BT2 A;  1AVG L;  2DOI A;  5CS5 A;  1TBR J;  3EDX A;  1JOU A;  1TB6 L;  2I9B A;  5CT1 A;  1PKR A;  4NZQ A;  3HN4 A;  1PMK A;  2I9A A;  3LU9 A;  1GMO A;  1PML A;  4RKO A;  2PF1 A;  3B9F L;  3GIS A;  1A0H A;  4BVW A;  1I5K A;  1BHT A;  3HKI A;  2HPQ P;  3KIV A;  2SPT A;  2ODY A;  1URK A;  5COE A;  2PV9 A;  5CS9 A;  1GP9 A;  4BVV A;  4CIK A;  1CEB A;  5CP9 A;  2QJ2 A;  4BVC A;  4HZH A;  5CT2 A;  3E6P L;  4BV5 A;  3SP8 A;  2PK4 A;  4BVD A;  2FEB A;  5HPG A;  2K51 A;  1KDU A;  1NL1 A;  1TQ7 A;  2QJ4 A;  3BT1 A;  2PUX A;  1HPK A;  1NL2 A; 
#chains in the Genus database with same CATH homology
 1PK2 A;  3BEI A;  2A1D A;  3MKP A;  4A5T S;  3BEF A;  4D3C A;  2KJ4 A;  2L0S A;  3K65 A;  1KIV A;  1B2I A;  4BV7 A;  2DOH X;  5CS3 A;  4DUR A;  2HPP P;  4DY7 A;  1NK1 A;  3U73 A;  1KRN A;  2PF2 A;  1Z8J A;  4IUA A;  3LAQ A;  1GMN A;  1JFN A;  1TBQ J;  2FD6 A;  1I71 A;  1CEA A;  1JMO L;  4KIV A;  1TPK A;  3HK6 A;  1PK4 A;  1HPJ A;  4O03 A;  3NXP A;  2PGQ A;  5CSQ A;  2KNF A;  2B5T A;  1KI0 A;  5CS1 A;  2K4R A;  5CT3 A;  3BT2 A;  1AVG L;  2DOI A;  5CS5 A;  1TBR J;  3EDX A;  1JOU A;  1TB6 L;  2I9B A;  5CT1 A;  1PKR A;  4NZQ A;  3HN4 A;  1PMK A;  2I9A A;  3LU9 A;  1GMO A;  1PML A;  4RKO A;  2PF1 A;  3B9F L;  3GIS A;  1A0H A;  4BVW A;  1I5K A;  1BHT A;  3HKI A;  2HPQ P;  3KIV A;  2SPT A;  2ODY A;  1URK A;  5COE A;  2PV9 A;  5CS9 A;  1GP9 A;  4BVV A;  4CIK A;  1CEB A;  5CP9 A;  2QJ2 A;  4BVC A;  4HZH A;  5CT2 A;  3E6P L;  4BV5 A;  3SP8 A;  2PK4 A;  4BVD A;  2FEB A;  5HPG A;  2K51 A;  1KDU A;  1NL1 A;  1TQ7 A;  2QJ4 A;  3BT1 A;  2PUX A;  1HPK A;  1NL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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