4BG1A

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 1-(3-carboxypropyl)-1-methylpyrrolidin-1-ium chloride
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
385
structure length
385
Chain Sequence
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords GAMMA-BUTYROBETAINE DIOXYGENASE
total genus 119
structure length 385
sequence length 385
ec nomenclature ec 1.14.11.1: Gamma-butyrobetaine dioxygenase.
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02668 TauD Taurine catabolism dioxygenase TauD, TfdA family
A PF06155 DUF971 Protein of unknown function (DUF971)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2020.30 Alpha Beta 2-Layer Sandwich NE0471 N-terminal domain-like NE0471 N-terminal domain-like 4bg1A01
3.60.130.10 Alpha Beta 4-Layer Sandwich Double-stranded beta-helix Clavaminate synthase-like 4bg1A02
1GVGA 4M26A 4Y0EA 2R6SA 5J92A 3N6WA 4CVYA 4BHIA 1OS7A 4C8RA 2WBQA 3SWTA 4BHFA 2WBOA 1Y0ZA 2Q4AA 5HSXA 3O2GA 3R1JA 4BHGA 4M25A 1DS0A 4BGMA 4M2CA 3V17A 1OIJA 4NE0A 1NX8A 1VZ5A 3EATX 4BG1A 1OIJB 4BGKA 4M2EA 4M27A 1DS1A 1OIKA 1OIJC 2OG6A 4FFAA 4J5IA 4M2GA 3V15A 4M2FA 1DRYA 1GQWA 1OTJA 4YLMX 2OG7A 2WBPA 1JR7A 4C5WA 1OIHA 3PVJA 1DRTA 4OJ8A 3LUUA 1OIIA 5KEUA 2OG5A 4M23A 1VZ4A 1NX4A 3MS5A 1GY9A 4M2IA 4CWDA
chains in the Genus database with same CATH superfamily
1GVGA 4M26A 4Y0EA 2AUWA 2R6SA 5J92A 1PG6A 3N6WA 4CVYA 4BHIA 1OS7A 4C8RA 2WBQA 3SWTA 4BHFA 2WBOA 1Y0ZA 2Q4AA 5HSXA 3O2GA 3R1JA 4BHGA 4M25A 1DS0A 4BGMA 4M2CA 3V17A 1OIJA 4NE0A 1YOXA 1NX8A 1VZ5A 3EATX 4BG1A 1OIJB 4BGKA 4M2EA 4M27A 3K8RA 1DS1A 1OIKA 1OIJC 2OG6A 4FFAA 4J5IA 4M2GA 3V15A 4M2FA 1DRYA 1GQWA 1OTJA 2X8NA 4YLMX 2OG7A 2WBPA 1JR7A 4C5WA 1OIHA 3PVJA 1DRTA 4OJ8A 3LUUA 1OIIA 5KEUA 2OG5A 4M23A 1VZ4A 1NX4A 3MS5A 1GY9A 4M2IA 4CWDA
chains in the Genus database with same CATH topology
4M26A 2WA4A 4CVYA 1OS7A 1YCIA 2WBQA 3SWTA 4BHFA 4AI8A 4JAAA 1DS0A 4M2CA 4Z1VA 1H2KA 2Y0IA 3LUUA 1H2NA 2OG5A 4M23A 1VZ4A 3MS5A 4CWDA 2ILMA 5J92A 1MZEA 1H2MA 4B7KA 3O2GA 1IZ3A 1OIJA 1VZ5A 4M2EA 4M27A 2OG6A 2CGNA 3KCXA 1GQWA 4YLMX 5JWPA 3P3PA 4C5WA 1OIIA 4M2FA 4M25A 5KEUA 1GVGA 3N6WA 4BHIA 3OD4A 4C8RA 2W0XA 2YDEA 5HSXA 3R1JA 4Z2WA 4BGMA 3KCYA 3EATX 4BG1A 1OIJB 4BGKA 4BIOA 1OIJC 1OIKA 4FFAA 2YC0A 1DRYA 2OG7A 2XUMA 1OIHA 3D8CA 1H2LA 2X8NA 1GY9A 4M2IA 4Y0EA 2R6SA 4NR1A 2CGOA 2WBOA 1Y0ZA 2Q4AA 2WA3A 3P3NA 4BHGA 3V17A 4NE0A 3K8RA 1DS1A 4M2GA 3V15A 4J5IA 1OTJA 1MZFA 2WBPA 1JR7A 3PVJA 1DRTA 4OJ8A 4B7EA 1NX4A 1NX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GVG A;  4M26 A;  4Y0E A;  2R6S A;  5J92 A;  3N6W A;  4CVY A;  4BHI A;  1OS7 A;  4C8R A;  2WBQ A;  3SWT A;  4BHF A;  2WBO A;  1Y0Z A;  2Q4A A;  5HSX A;  3O2G A;  3R1J A;  4BHG A;  4M25 A;  1DS0 A;  4BGM A;  4M2C A;  3V17 A;  1OIJ A;  4NE0 A;  1NX8 A;  1VZ5 A;  3EAT X;  4BG1 A;  1OIJ B;  4BGK A;  4M2E A;  4M27 A;  1DS1 A;  1OIK A;  1OIJ C;  2OG6 A;  4FFA A;  4J5I A;  4M2G A;  3V15 A;  4M2F A;  1DRY A;  1GQW A;  1OTJ A;  4YLM X;  2OG7 A;  2WBP A;  1JR7 A;  4C5W A;  1OIH A;  3PVJ A;  1DRT A;  4OJ8 A;  3LUU A;  1OII A;  5KEU A;  2OG5 A;  4M23 A;  1VZ4 A;  1NX4 A;  3MS5 A;  1GY9 A;  4M2I A;  4CWD A; 
#chains in the Genus database with same CATH topology
 1GVG A;  4M26 A;  4Y0E A;  2AUW A;  2R6S A;  5J92 A;  1PG6 A;  3N6W A;  4CVY A;  4BHI A;  1OS7 A;  4C8R A;  2WBQ A;  3SWT A;  4BHF A;  2WBO A;  1Y0Z A;  2Q4A A;  5HSX A;  3O2G A;  3R1J A;  4BHG A;  4M25 A;  1DS0 A;  4BGM A;  4M2C A;  3V17 A;  1OIJ A;  4NE0 A;  1YOX A;  1NX8 A;  1VZ5 A;  3EAT X;  4BG1 A;  1OIJ B;  4BGK A;  4M2E A;  4M27 A;  3K8R A;  1DS1 A;  1OIK A;  1OIJ C;  2OG6 A;  4FFA A;  4J5I A;  4M2G A;  3V15 A;  4M2F A;  1DRY A;  1GQW A;  1OTJ A;  2X8N A;  4YLM X;  2OG7 A;  2WBP A;  1JR7 A;  4C5W A;  1OIH A;  3PVJ A;  1DRT A;  4OJ8 A;  3LUU A;  1OII A;  5KEU A;  2OG5 A;  4M23 A;  1VZ4 A;  1NX4 A;  3MS5 A;  1GY9 A;  4M2I A;  4CWD A; 
#chains in the Genus database with same CATH homology
 4M26 A;  2WA4 A;  4CVY A;  1OS7 A;  1YCI A;  2WBQ A;  3SWT A;  4BHF A;  4AI8 A;  4JAA A;  1DS0 A;  4M2C A;  4Z1V A;  1H2K A;  2Y0I A;  3LUU A;  1H2N A;  2OG5 A;  4M23 A;  1VZ4 A;  3MS5 A;  4CWD A;  2ILM A;  5J92 A;  1MZE A;  1H2M A;  4B7K A;  3O2G A;  1IZ3 A;  1OIJ A;  1VZ5 A;  4M2E A;  4M27 A;  2OG6 A;  2CGN A;  3KCX A;  1GQW A;  4YLM X;  5JWP A;  3P3P A;  4C5W A;  1OII A;  4M2F A;  4M25 A;  5KEU A;  1GVG A;  3N6W A;  4BHI A;  3OD4 A;  4C8R A;  2W0X A;  2YDE A;  5HSX A;  3R1J A;  4Z2W A;  4BGM A;  3KCY A;  3EAT X;  4BG1 A;  1OIJ B;  4BGK A;  4BIO A;  1OIJ C;  1OIK A;  4FFA A;  2YC0 A;  1DRY A;  2OG7 A;  2XUM A;  1OIH A;  3D8C A;  1H2L A;  2X8N A;  1GY9 A;  4M2I A;  4Y0E A;  2R6S A;  4NR1 A;  2CGO A;  2WBO A;  1Y0Z A;  2Q4A A;  2WA3 A;  3P3N A;  4BHG A;  3V17 A;  4NE0 A;  3K8R A;  1DS1 A;  4M2G A;  3V15 A;  4J5I A;  1OTJ A;  1MZF A;  2WBP A;  1JR7 A;  3PVJ A;  1DRT A;  4OJ8 A;  4B7E A;  1NX4 A;  1NX8 A; 
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