4BG1A

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 1-(3-carboxypropyl)-1-methylpyrrolidin-1-ium chloride
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
385
structure length
385
Chain Sequence
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords GAMMA-BUTYROBETAINE DIOXYGENASE
total genus 119
structure length 385
sequence length 385
ec nomenclature ec 1.14.11.1: Gamma-butyrobetaine dioxygenase.
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02668 TauD Taurine catabolism dioxygenase TauD, TfdA family
A PF06155 DUF971 Protein of unknown function (DUF971)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2020.30 Alpha Beta 2-Layer Sandwich NE0471 N-terminal domain-like NE0471 N-terminal domain-like 4bg1A01
3.60.130.10 Alpha Beta 4-Layer Sandwich Double-stranded beta-helix Clavaminate synthase-like 4bg1A02
4M23A 2OG5A 1OIHA 4BG1A 4M2GA 5HSXA 4C5WA 1OS7A 3R1JA 2OG7A 4FFAA 1GQWA 1OIIA 2R6SA 3EATX 1GVGA 1OIJC 4YLMX 3N6WA 4OJ8A 2Q4AA 4M25A 4BHIA 5J92A 4CVYA 4M27A 4M2CA 3PVJA 1DRYA 1Y0ZA 4J5IA 3SWTA 1OIJA 3O2GA 4Y0EA 4M26A 5KEUA 4M2IA 4C8RA 3MS5A 1OTJA 1DS1A 4BGKA 4BGMA 4BHGA 3V15A 2WBQA 1DS0A 1VZ4A 4BHFA 3V17A 1GY9A 1NX8A 1JR7A 1VZ5A 4NE0A 2OG6A 4M2EA 4M2FA 4CWDA 3LUUA 1DRTA 2WBOA 1OIKA 2WBPA 1OIJB 1NX4A
chains in the Genus database with same CATH superfamily
4M23A 2OG5A 1OIHA 2X8NA 4BG1A 4M2GA 1YOXA 5HSXA 4C5WA 1OS7A 3R1JA 2OG7A 4FFAA 1GQWA 1OIIA 2R6SA 3EATX 1GVGA 1OIJC 4YLMX 3N6WA 4OJ8A 2Q4AA 4M25A 4BHIA 5J92A 4CVYA 3K8RA 4M27A 4M2CA 3PVJA 1DRYA 1Y0ZA 4J5IA 3SWTA 1OIJA 3O2GA 4Y0EA 4M26A 2AUWA 4M2IA 5KEUA 4C8RA 3MS5A 1OTJA 1DS1A 4BGKA 4BGMA 4BHGA 3V15A 2WBQA 1DS0A 1VZ4A 4BHFA 3V17A 1GY9A 1NX8A 1JR7A 1VZ5A 4NE0A 1PG6A 2OG6A 4M2EA 4M2FA 4CWDA 3LUUA 1DRTA 2WBOA 1OIKA 2WBPA 1OIJB 1NX4A
chains in the Genus database with same CATH topology
4NR1A 4M2GA 3R1JA 4FFAA 1H2NA 1OIJC 4YLMX 4CVYA 2YC0A 3K8RA 2CGOA 3PVJA 1IZ3A 4Y0EA 1DS1A 2YDEA 2CGNA 1DS0A 1VZ4A 1JR7A 2WA4A 2OG6A 3KCXA 4M26A 3P3NA 2WBPA 1OIJB 2OG5A 1OIHA 4C5WA 1OS7A 2OG7A 1GQWA 1OIIA 1GVGA 4BHIA 5J92A 3SWTA 1OIJA 3MS5A 2Y0IA 1MZFA 2WA3A 2WBQA 4BHFA 1NX8A 1VZ5A 3LUUA 1OIKA 4M2EA 4M23A 2X8NA 4Z1VA 5HSXA 2W0XA 3EATX 4AI8A 3N6WA 4OJ8A 4Z2WA 4M2CA 4B7EA 1DRYA 1Y0ZA 4J5IA 5KEUA 4M2IA 4C8RA 4B7KA 2ILMA 4NE0A 4M2FA 4CWDA 3V17A 4BIOA 3D8CA 4BG1A 4JAAA 3OD4A 2R6SA 1H2MA 2Q4AA 1YCIA 4M25A 4M27A 2XUMA 3O2GA 5JWPA 1H2LA 1OTJA 3V15A 4BGKA 4BGMA 4BHGA 1MZEA 3P3PA 1GY9A 1H2KA 3KCYA 1DRTA 2WBOA 1NX4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4M23 A;  2OG5 A;  1OIH A;  4BG1 A;  4M2G A;  5HSX A;  4C5W A;  1OS7 A;  3R1J A;  2OG7 A;  4FFA A;  1GQW A;  1OII A;  2R6S A;  3EAT X;  1GVG A;  1OIJ C;  4YLM X;  3N6W A;  4OJ8 A;  2Q4A A;  4M25 A;  4BHI A;  5J92 A;  4CVY A;  4M27 A;  4M2C A;  3PVJ A;  1DRY A;  1Y0Z A;  4J5I A;  3SWT A;  1OIJ A;  3O2G A;  4Y0E A;  4M26 A;  5KEU A;  4M2I A;  4C8R A;  3MS5 A;  1OTJ A;  1DS1 A;  4BGK A;  4BGM A;  4BHG A;  3V15 A;  2WBQ A;  1DS0 A;  1VZ4 A;  4BHF A;  3V17 A;  1GY9 A;  1NX8 A;  1JR7 A;  1VZ5 A;  4NE0 A;  2OG6 A;  4M2E A;  4M2F A;  4CWD A;  3LUU A;  1DRT A;  2WBO A;  1OIK A;  2WBP A;  1OIJ B;  1NX4 A; 
#chains in the Genus database with same CATH topology
 4M23 A;  2OG5 A;  1OIH A;  2X8N A;  4BG1 A;  4M2G A;  1YOX A;  5HSX A;  4C5W A;  1OS7 A;  3R1J A;  2OG7 A;  4FFA A;  1GQW A;  1OII A;  2R6S A;  3EAT X;  1GVG A;  1OIJ C;  4YLM X;  3N6W A;  4OJ8 A;  2Q4A A;  4M25 A;  4BHI A;  5J92 A;  4CVY A;  3K8R A;  4M27 A;  4M2C A;  3PVJ A;  1DRY A;  1Y0Z A;  4J5I A;  3SWT A;  1OIJ A;  3O2G A;  4Y0E A;  4M26 A;  2AUW A;  4M2I A;  5KEU A;  4C8R A;  3MS5 A;  1OTJ A;  1DS1 A;  4BGK A;  4BGM A;  4BHG A;  3V15 A;  2WBQ A;  1DS0 A;  1VZ4 A;  4BHF A;  3V17 A;  1GY9 A;  1NX8 A;  1JR7 A;  1VZ5 A;  4NE0 A;  1PG6 A;  2OG6 A;  4M2E A;  4M2F A;  4CWD A;  3LUU A;  1DRT A;  2WBO A;  1OIK A;  2WBP A;  1OIJ B;  1NX4 A; 
#chains in the Genus database with same CATH homology
 4NR1 A;  4M2G A;  3R1J A;  4FFA A;  1H2N A;  1OIJ C;  4YLM X;  4CVY A;  2YC0 A;  3K8R A;  2CGO A;  3PVJ A;  1IZ3 A;  4Y0E A;  1DS1 A;  2YDE A;  2CGN A;  1DS0 A;  1VZ4 A;  1JR7 A;  2WA4 A;  2OG6 A;  3KCX A;  4M26 A;  3P3N A;  2WBP A;  1OIJ B;  2OG5 A;  1OIH A;  4C5W A;  1OS7 A;  2OG7 A;  1GQW A;  1OII A;  1GVG A;  4BHI A;  5J92 A;  3SWT A;  1OIJ A;  3MS5 A;  2Y0I A;  1MZF A;  2WA3 A;  2WBQ A;  4BHF A;  1NX8 A;  1VZ5 A;  3LUU A;  1OIK A;  4M2E A;  4M23 A;  2X8N A;  4Z1V A;  5HSX A;  2W0X A;  3EAT X;  4AI8 A;  3N6W A;  4OJ8 A;  4Z2W A;  4M2C A;  4B7E A;  1DRY A;  1Y0Z A;  4J5I A;  5KEU A;  4M2I A;  4C8R A;  4B7K A;  2ILM A;  4NE0 A;  4M2F A;  4CWD A;  3V17 A;  4BIO A;  3D8C A;  4BG1 A;  4JAA A;  3OD4 A;  2R6S A;  1H2M A;  2Q4A A;  1YCI A;  4M25 A;  4M27 A;  2XUM A;  3O2G A;  5JWP A;  1H2L A;  1OTJ A;  3V15 A;  4BGK A;  4BGM A;  4BHG A;  1MZE A;  3P3P A;  1GY9 A;  1H2K A;  3KCY A;  1DRT A;  2WBO A;  1NX4 A; 
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