4BGMA

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 3-carboxy-n-(2-fluoroethyl)-n,n-dimethylpropan-1- aminium chloride
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
384
structure length
384
Chain Sequence
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords GAMMA-BUTYROBETAINE DIOXYGENASE
total genus 119
structure length 384
sequence length 384
ec nomenclature ec 1.14.11.1: Gamma-butyrobetaine dioxygenase.
pdb deposition date 2013-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02668 TauD Taurine catabolism dioxygenase TauD, TfdA family
A PF06155 DUF971 Protein of unknown function (DUF971)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2020.30 Alpha Beta 2-Layer Sandwich NE0471 N-terminal domain-like NE0471 N-terminal domain-like 4bgmA01
3.60.130.10 Alpha Beta 4-Layer Sandwich Double-stranded beta-helix Clavaminate synthase-like 4bgmA02
1OIJC 4M2IA 3V15A 4BHIA 1GVGA 1DS0A 1OIHA 2WBOA 2WBPA 1NX8A 4CWDA 3EATX 1OIJB 4M23A 4M2CA 2OG7A 4C8RA 3LUUA 1OIKA 4BHGA 2R6SA 4BG1A 4M2EA 4OJ8A 1VZ5A 4YLMX 1Y0ZA 3O2GA 3N6WA 1GY9A 4FFAA 5KEUA 3PVJA 5HSXA 3R1JA 4M26A 4CVYA 4BHFA 1OIJA 1OS7A 4M25A 1NX4A 1DS1A 4M2FA 1GQWA 3V17A 3SWTA 4BGKA 3MS5A 4Y0EA 1OIIA 1OTJA 2OG6A 4J5IA 4M2GA 4C5WA 2WBQA 4M27A 4BGMA 1VZ4A 1DRTA 1DRYA 2Q4AA 4NE0A 2OG5A 5J92A 1JR7A
chains in the Genus database with same CATH superfamily
1OIJC 4M2IA 3V15A 4BHIA 1GVGA 1DS0A 1OIHA 2WBOA 2WBPA 1NX8A 4CWDA 3EATX 1OIJB 4M23A 4M2CA 2OG7A 4C8RA 3LUUA 1OIKA 4BHGA 2R6SA 4BG1A 4M2EA 4OJ8A 1VZ5A 4YLMX 2X8NA 1Y0ZA 3O2GA 3N6WA 1GY9A 4FFAA 5KEUA 3PVJA 5HSXA 3R1JA 4M26A 4CVYA 4BHFA 1OIJA 1OS7A 1PG6A 3K8RA 4M25A 1NX4A 1DS1A 4M2FA 1GQWA 3V17A 3SWTA 2AUWA 4BGKA 3MS5A 4Y0EA 1OIIA 1OTJA 2OG6A 1YOXA 4J5IA 4M2GA 4C5WA 2WBQA 4M27A 4BGMA 1VZ4A 1DRTA 1DRYA 2Q4AA 4NE0A 2OG5A 5J92A 1JR7A
chains in the Genus database with same CATH topology
4M2IA 3V15A 1YCIA 1OIHA 3EATX 4M2CA 4C8RA 2R6SA 4BG1A 1Y0ZA 3O2GA 1H2NA 4FFAA 4AI8A 4Z1VA 3P3NA 4CVYA 4BIOA 4BHFA 2XUMA 3SWTA 4BGKA 1MZEA 1OIIA 2OG6A 2WBQA 1DRTA 2OG5A 2W0XA 1GVGA 2Y0IA 2WBOA 2WBPA 4CWDA 1OIJB 4M2EA 1OIKA 4BHGA 1IZ3A 1GY9A 5HSXA 4M26A 3P3PA 1OS7A 4M25A 4B7EA 4M2FA 3MS5A 4C5WA 4M27A 4BGMA 4NR1A 1DRYA 5J92A 1OIJC 2WA4A 1DS0A 1NX8A 4M23A 3KCXA 3LUUA 4OJ8A 5JWPA 3KCYA 4YLMX 1VZ5A 3N6WA 5KEUA 3R1JA 1OIJA 1NX4A 1DS1A 1H2KA 1GQWA 3V17A 4Y0EA 4M2GA 1MZFA 4NE0A 2YC0A 2ILMA 4BHIA 2CGNA 2OG7A 2YDEA 4Z2WA 2X8NA 3D8CA 3PVJA 3OD4A 1H2LA 3K8RA 4B7KA 2WA3A 1H2MA 1OTJA 4J5IA 2CGOA 1VZ4A 2Q4AA 4JAAA 1JR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OIJ C;  4M2I A;  3V15 A;  4BHI A;  1GVG A;  1DS0 A;  1OIH A;  2WBO A;  2WBP A;  1NX8 A;  4CWD A;  3EAT X;  1OIJ B;  4M23 A;  4M2C A;  2OG7 A;  4C8R A;  3LUU A;  1OIK A;  4BHG A;  2R6S A;  4BG1 A;  4M2E A;  4OJ8 A;  1VZ5 A;  4YLM X;  1Y0Z A;  3O2G A;  3N6W A;  1GY9 A;  4FFA A;  5KEU A;  3PVJ A;  5HSX A;  3R1J A;  4M26 A;  4CVY A;  4BHF A;  1OIJ A;  1OS7 A;  4M25 A;  1NX4 A;  1DS1 A;  4M2F A;  1GQW A;  3V17 A;  3SWT A;  4BGK A;  3MS5 A;  4Y0E A;  1OII A;  1OTJ A;  2OG6 A;  4J5I A;  4M2G A;  4C5W A;  2WBQ A;  4M27 A;  4BGM A;  1VZ4 A;  1DRT A;  1DRY A;  2Q4A A;  4NE0 A;  2OG5 A;  5J92 A;  1JR7 A; 
#chains in the Genus database with same CATH topology
 1OIJ C;  4M2I A;  3V15 A;  4BHI A;  1GVG A;  1DS0 A;  1OIH A;  2WBO A;  2WBP A;  1NX8 A;  4CWD A;  3EAT X;  1OIJ B;  4M23 A;  4M2C A;  2OG7 A;  4C8R A;  3LUU A;  1OIK A;  4BHG A;  2R6S A;  4BG1 A;  4M2E A;  4OJ8 A;  1VZ5 A;  4YLM X;  2X8N A;  1Y0Z A;  3O2G A;  3N6W A;  1GY9 A;  4FFA A;  5KEU A;  3PVJ A;  5HSX A;  3R1J A;  4M26 A;  4CVY A;  4BHF A;  1OIJ A;  1OS7 A;  1PG6 A;  3K8R A;  4M25 A;  1NX4 A;  1DS1 A;  4M2F A;  1GQW A;  3V17 A;  3SWT A;  2AUW A;  4BGK A;  3MS5 A;  4Y0E A;  1OII A;  1OTJ A;  2OG6 A;  1YOX A;  4J5I A;  4M2G A;  4C5W A;  2WBQ A;  4M27 A;  4BGM A;  1VZ4 A;  1DRT A;  1DRY A;  2Q4A A;  4NE0 A;  2OG5 A;  5J92 A;  1JR7 A; 
#chains in the Genus database with same CATH homology
 4M2I A;  3V15 A;  1YCI A;  1OIH A;  3EAT X;  4M2C A;  4C8R A;  2R6S A;  4BG1 A;  1Y0Z A;  3O2G A;  1H2N A;  4FFA A;  4AI8 A;  4Z1V A;  3P3N A;  4CVY A;  4BIO A;  4BHF A;  2XUM A;  3SWT A;  4BGK A;  1MZE A;  1OII A;  2OG6 A;  2WBQ A;  1DRT A;  2OG5 A;  2W0X A;  1GVG A;  2Y0I A;  2WBO A;  2WBP A;  4CWD A;  1OIJ B;  4M2E A;  1OIK A;  4BHG A;  1IZ3 A;  1GY9 A;  5HSX A;  4M26 A;  3P3P A;  1OS7 A;  4M25 A;  4B7E A;  4M2F A;  3MS5 A;  4C5W A;  4M27 A;  4BGM A;  4NR1 A;  1DRY A;  5J92 A;  1OIJ C;  2WA4 A;  1DS0 A;  1NX8 A;  4M23 A;  3KCX A;  3LUU A;  4OJ8 A;  5JWP A;  3KCY A;  4YLM X;  1VZ5 A;  3N6W A;  5KEU A;  3R1J A;  1OIJ A;  1NX4 A;  1DS1 A;  1H2K A;  1GQW A;  3V17 A;  4Y0E A;  4M2G A;  1MZF A;  4NE0 A;  2YC0 A;  2ILM A;  4BHI A;  2CGN A;  2OG7 A;  2YDE A;  4Z2W A;  2X8N A;  3D8C A;  3PVJ A;  3OD4 A;  1H2L A;  3K8R A;  4B7K A;  2WA3 A;  1H2M A;  1OTJ A;  4J5I A;  2CGO A;  1VZ4 A;  2Q4A A;  4JAA A;  1JR7 A; 
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