The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
119
|
sequence length |
384
|
structure length |
384
|
Chain Sequence |
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb |
| molecule tags |
Oxidoreductase
|
| source organism |
Homo sapiens
|
| molecule keywords |
GAMMA-BUTYROBETAINE DIOXYGENASE
|
| total genus |
119
|
| structure length |
384
|
| sequence length |
384
|
| ec nomenclature |
ec
1.14.11.1: Gamma-butyrobetaine dioxygenase. |
| pdb deposition date | 2013-03-27 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02668 | TauD | Taurine catabolism dioxygenase TauD, TfdA family |
| A | PF06155 | DUF971 | Protein of unknown function (DUF971) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | NE0471 N-terminal domain-like | NE0471 N-terminal domain-like | ||
| Alpha Beta | 4-Layer Sandwich | Double-stranded beta-helix | Clavaminate synthase-like |
#chains in the Genus database with same CATH superfamily 2Q4A A; 2WBQ A; 3PVJ A; 1NX4 A; 1NX8 A; 3V15 A; 1OIJ A; 1OIJ C; 1OTJ A; 4M2F A; 1DRT A; 2R6S A; 4M2G A; 1OIJ B; 3N6W A; 3LUU A; 3O2G A; 1GVG A; 4BHI A; 1GY9 A; 4C5W A; 1Y0Z A; 4CVY A; 1OIK A; 4FFA A; 4BG1 A; 1VZ4 A; 4M2C A; 4M26 A; 4C8R A; 3MS5 A; 4J5I A; 2OG7 A; 1OII A; 4BGM A; 2WBO A; 3R1J A; 4M27 A; 4BHF A; 4M2I A; 5HSX A; 4CWD A; 1JR7 A; 5KEU A; 4Y0E A; 1VZ5 A; 4M25 A; 4OJ8 A; 3EAT X; 3V17 A; 1DRY A; 4BGK A; 1DS0 A; 4M2E A; 1DS1 A; 1OS7 A; 4M23 A; 5J92 A; 1OIH A; 2WBP A; 4YLM X; 4NE0 A; 3SWT A; 2OG6 A; 2OG5 A; 1GQW A; 4BHG A; #chains in the Genus database with same CATH topology 3K8R A; 2Q4A A; 2WBQ A; 3PVJ A; 1NX4 A; 1NX8 A; 3V15 A; 1OIJ A; 1OIJ C; 1OTJ A; 4M2F A; 1DRT A; 2R6S A; 4M2G A; 1OIJ B; 2X8N A; 3N6W A; 3LUU A; 3O2G A; 1GVG A; 4BHI A; 1GY9 A; 2AUW A; 1YOX A; 4C5W A; 1Y0Z A; 4CVY A; 1OIK A; 4FFA A; 4BG1 A; 1VZ4 A; 4M2C A; 4M26 A; 4C8R A; 3MS5 A; 4J5I A; 2OG7 A; 1OII A; 4BGM A; 2WBO A; 3R1J A; 4M27 A; 4BHF A; 4M2I A; 5HSX A; 4CWD A; 1JR7 A; 5KEU A; 4Y0E A; 1VZ5 A; 4M25 A; 4OJ8 A; 3EAT X; 3V17 A; 1DRY A; 4BGK A; 1DS0 A; 4M2E A; 1DS1 A; 1OS7 A; 1PG6 A; 4M23 A; 5J92 A; 1OIH A; 2WBP A; 4YLM X; 4NE0 A; 3SWT A; 2OG6 A; 2OG5 A; 1GQW A; 4BHG A; #chains in the Genus database with same CATH homology 3V15 A; 1OIJ C; 2CGN A; 3N6W A; 4C5W A; 4Z1V A; 4B7E A; 2YC0 A; 4JAA A; 2CGO A; 1H2K A; 4BHF A; 4M2I A; 3OD4 A; 4OJ8 A; 1IZ3 A; 4M2E A; 1H2L A; 5J92 A; 3K8R A; 3PVJ A; 1NX4 A; 2R6S A; 1OIJ B; 1GVG A; 3LUU A; 1GY9 A; 1Y0Z A; 4M26 A; 3MS5 A; 3D8C A; 4BGM A; 2WBO A; 1H2N A; 2W0X A; 1VZ5 A; 1H2M A; 4BIO A; 1DS0 A; 5JWP A; 4M23 A; 3SWT A; 2OG6 A; 1GQW A; 2Q4A A; 2WA3 A; 2WA4 A; 1NX8 A; 1OIJ A; 1OTJ A; 1DRT A; 3O2G A; 2XUM A; 4Z2W A; 3KCX A; 1MZF A; 1VZ4 A; 4J5I A; 2ILM A; 2OG7 A; 1OII A; 3KCY A; 5HSX A; 4CWD A; 5KEU A; 1YCI A; 4Y0E A; 4M25 A; 3V17 A; 4BGK A; 1DS1 A; 2WBP A; 4YLM X; 3P3P A; 4NE0 A; 2OG5 A; 2WBQ A; 4B7K A; 4M2F A; 4M2G A; 2X8N A; 4BHI A; 3P3N A; 4CVY A; 1OIK A; 4FFA A; 4BG1 A; 4M2C A; 4NR1 A; 4AI8 A; 4C8R A; 1MZE A; 2Y0I A; 3R1J A; 4M27 A; 1JR7 A; 2YDE A; 1DRY A; 1OS7 A; 1OIH A; 3EAT X; 4BHG A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
