4BHIA

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 3-(1,1,1,2-tetramethylhydrazin-1-ium-2-yl)propanoate
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
385
structure length
385
Chain Sequence
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords GAMMA-BUTYROBETAINE DIOXYGENASE
total genus 119
structure length 385
sequence length 385
ec nomenclature ec 1.14.11.1: Gamma-butyrobetaine dioxygenase.
pdb deposition date 2013-04-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02668 TauD Taurine catabolism dioxygenase TauD, TfdA family
A PF06155 DUF971 Protein of unknown function (DUF971)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2020.30 Alpha Beta 2-Layer Sandwich NE0471 N-terminal domain-like NE0471 N-terminal domain-like 4bhiA01
3.60.130.10 Alpha Beta 4-Layer Sandwich Double-stranded beta-helix Clavaminate synthase-like 4bhiA02
1NX8A 4C5WA 5HSXA 2OG7A 4FFAA 4BHIA 1DS0A 4CVYA 4NE0A 1DRYA 2OG5A 4BGKA 4CWDA 2OG6A 2Q4AA 4M2CA 1OIJA 4M2FA 2WBPA 1GVGA 1JR7A 4BGMA 4Y0EA 1VZ5A 4M2IA 4BG1A 1GY9A 2WBQA 4OJ8A 3R1JA 3SWTA 1OIIA 4M2EA 4C8RA 1OIKA 3PVJA 1DRTA 1OS7A 4M25A 3O2GA 4BHFA 4M27A 2R6SA 4J5IA 4YLMX 3V15A 3V17A 2WBOA 5KEUA 3MS5A 1OTJA 1OIJC 3EATX 4BHGA 4M23A 1VZ4A 1OIHA 1DS1A 1GQWA 1OIJB 4M2GA 1Y0ZA 1NX4A 3N6WA 4M26A 5J92A 3LUUA
chains in the Genus database with same CATH superfamily
1NX8A 4C5WA 5HSXA 2OG7A 4FFAA 4BHIA 1DS0A 4CVYA 4NE0A 1DRYA 2OG5A 4BGKA 4CWDA 2OG6A 2Q4AA 4M2CA 1OIJA 4M2FA 2WBPA 1GVGA 1JR7A 4BGMA 1YOXA 4Y0EA 1VZ5A 4M2IA 4BG1A 1GY9A 2WBQA 4OJ8A 3R1JA 3SWTA 1OIIA 4M2EA 4C8RA 1OIKA 3PVJA 3K8RA 1DRTA 1OS7A 4M25A 3O2GA 4BHFA 2X8NA 2R6SA 4J5IA 4M27A 4YLMX 3V15A 3V17A 2WBOA 5KEUA 3MS5A 1OTJA 1OIJC 3EATX 4BHGA 1PG6A 2AUWA 4M23A 1VZ4A 1OIHA 1DS1A 1GQWA 1OIJB 4M2GA 1Y0ZA 1NX4A 3N6WA 4M26A 5J92A 3LUUA
chains in the Genus database with same CATH topology
5HSXA 2CGNA 4CVYA 2OG5A 2W0XA 1H2MA 2WBPA 1JR7A 4M2IA 1GY9A 1H2KA 1OIIA 4NR1A 3D8CA 4M25A 4M27A 2R6SA 1OTJA 1OIJC 4Z2WA 2ILMA 2WA3A 1OIJB 1GQWA 2CGOA 4M2GA 4B7KA 2WA4A 2XUMA 4M26A 3LUUA 1NX8A 4AI8A 2YDEA 4BHIA 4FFAA 4NE0A 4BGKA 5JWPA 1GVGA 3KCYA 1VZ5A 4C8RA 3K8RA 1DRTA 3O2GA 4BHFA 4J5IA 1MZEA 4M23A 4B7EA 5J92A 1YCIA 4C5WA 2OG7A 1DS0A 1DRYA 4M2CA 2Q4AA 1OIJA 4M2FA 4BGMA 4BG1A 1IZ3A 2WBQA 4OJ8A 4BIOA 3R1JA 4Z1VA 1MZFA 3PVJA 1OS7A 2X8NA 3V17A 2WBOA 5KEUA 3MS5A 3EATX 4BHGA 3P3PA 1OIHA 4JAAA 1NX4A 3OD4A 3P3NA 1H2LA 2Y0IA 4CWDA 2OG6A 3KCXA 4Y0EA 3SWTA 4M2EA 1OIKA 2YC0A 4YLMX 3V15A 1H2NA 1VZ4A 1DS1A 1Y0ZA 3N6WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NX8 A;  4C5W A;  5HSX A;  2OG7 A;  4FFA A;  4BHI A;  1DS0 A;  4CVY A;  4NE0 A;  1DRY A;  2OG5 A;  4BGK A;  4CWD A;  2OG6 A;  2Q4A A;  4M2C A;  1OIJ A;  4M2F A;  2WBP A;  1GVG A;  1JR7 A;  4BGM A;  4Y0E A;  1VZ5 A;  4M2I A;  4BG1 A;  1GY9 A;  2WBQ A;  4OJ8 A;  3R1J A;  3SWT A;  1OII A;  4M2E A;  4C8R A;  1OIK A;  3PVJ A;  1DRT A;  1OS7 A;  4M25 A;  3O2G A;  4BHF A;  4M27 A;  2R6S A;  4J5I A;  4YLM X;  3V15 A;  3V17 A;  2WBO A;  5KEU A;  3MS5 A;  1OTJ A;  1OIJ C;  3EAT X;  4BHG A;  4M23 A;  1VZ4 A;  1OIH A;  1DS1 A;  1GQW A;  1OIJ B;  4M2G A;  1Y0Z A;  1NX4 A;  3N6W A;  4M26 A;  5J92 A;  3LUU A; 
#chains in the Genus database with same CATH topology
 1NX8 A;  4C5W A;  5HSX A;  2OG7 A;  4FFA A;  4BHI A;  1DS0 A;  4CVY A;  4NE0 A;  1DRY A;  2OG5 A;  4BGK A;  4CWD A;  2OG6 A;  2Q4A A;  4M2C A;  1OIJ A;  4M2F A;  2WBP A;  1GVG A;  1JR7 A;  4BGM A;  1YOX A;  4Y0E A;  1VZ5 A;  4M2I A;  4BG1 A;  1GY9 A;  2WBQ A;  4OJ8 A;  3R1J A;  3SWT A;  1OII A;  4M2E A;  4C8R A;  1OIK A;  3PVJ A;  3K8R A;  1DRT A;  1OS7 A;  4M25 A;  3O2G A;  4BHF A;  2X8N A;  2R6S A;  4J5I A;  4M27 A;  4YLM X;  3V15 A;  3V17 A;  2WBO A;  5KEU A;  3MS5 A;  1OTJ A;  1OIJ C;  3EAT X;  4BHG A;  1PG6 A;  2AUW A;  4M23 A;  1VZ4 A;  1OIH A;  1DS1 A;  1GQW A;  1OIJ B;  4M2G A;  1Y0Z A;  1NX4 A;  3N6W A;  4M26 A;  5J92 A;  3LUU A; 
#chains in the Genus database with same CATH homology
 5HSX A;  2CGN A;  4CVY A;  2OG5 A;  2W0X A;  1H2M A;  2WBP A;  1JR7 A;  4M2I A;  1GY9 A;  1H2K A;  1OII A;  4NR1 A;  3D8C A;  4M25 A;  4M27 A;  2R6S A;  1OTJ A;  1OIJ C;  4Z2W A;  2ILM A;  2WA3 A;  1OIJ B;  1GQW A;  2CGO A;  4M2G A;  4B7K A;  2WA4 A;  2XUM A;  4M26 A;  3LUU A;  1NX8 A;  4AI8 A;  2YDE A;  4BHI A;  4FFA A;  4NE0 A;  4BGK A;  5JWP A;  1GVG A;  3KCY A;  1VZ5 A;  4C8R A;  3K8R A;  1DRT A;  3O2G A;  4BHF A;  4J5I A;  1MZE A;  4M23 A;  4B7E A;  5J92 A;  1YCI A;  4C5W A;  2OG7 A;  1DS0 A;  1DRY A;  4M2C A;  2Q4A A;  1OIJ A;  4M2F A;  4BGM A;  4BG1 A;  1IZ3 A;  2WBQ A;  4OJ8 A;  4BIO A;  3R1J A;  4Z1V A;  1MZF A;  3PVJ A;  1OS7 A;  2X8N A;  3V17 A;  2WBO A;  5KEU A;  3MS5 A;  3EAT X;  4BHG A;  3P3P A;  1OIH A;  4JAA A;  1NX4 A;  3OD4 A;  3P3N A;  1H2L A;  2Y0I A;  4CWD A;  2OG6 A;  3KCX A;  4Y0E A;  3SWT A;  4M2E A;  1OIK A;  2YC0 A;  4YLM X;  3V15 A;  1H2N A;  1VZ4 A;  1DS1 A;  1Y0Z A;  3N6W A; 
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similar chains in the Genus database (?% sequence similarity)
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