4F3FC

Crystal structure of msln7-64 morab-009 fab complex
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
59
structure length
59
Chain Sequence
MCPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
pubmed doi rcsb
molecule keywords MORAb-009 Fab light chain
molecule tags Immune system
source organism Mus musculus
total genus 18
structure length 59
sequence length 59
ec nomenclature
pdb deposition date 2012-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.40 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 4f3fC00
4F3FC
chains in the Genus database with same CATH superfamily
1GXBA 4M0RA 1RRZA 4ZOFA 1KGZA 1UOUA 2WK6A 5C1RA 5BYTA 4EADA 4N8QA 3QQSA 4ZOJA 5BNEA 1ZYKA 4X59A 5EY3A 3QS8A 4X5AA 3TWPA 1AZYA 5C7SA 4X5EA 4XR5A 4GA5A 4EAFA 4GA6A 1VQUA 4X5BA 4YI7A 4X5CA 4F3FC 5EP8A 1BRWA 1V8GA 3QR9A 4IJ1A 4OWSA 3H5QA 2ELCA 2TPTA 1O17A 4GIUA 4ZOKA 4YYYA 4GKMA 4OWMA 2DSJA 4OWOA 4X58A 4OWQA 3QSAA 3R88A 3R6CA 4OWVA 1ZXYA 4N5VA 4X46A 2BPQA 4OWNA 4MUOA 4N93A 4GA4A 1KHDA 3UU1A 1RF8B 5BO2A 1ZVWA 4X5DA 2WK5A 5C2LA 4GTNA 2GVQA 2J0FA 1OTPA 4ZTVA 5BO3A 3GBRA 4OWUA 4YEKA 4LHMA 4HKMA
chains in the Genus database with same CATH topology
4GA6A 1RF8B 4F3FC 4GA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3F C; 
#chains in the Genus database with same CATH topology
 1GXB A;  4M0R A;  1RRZ A;  4ZOF A;  1KGZ A;  1UOU A;  2WK6 A;  5C1R A;  5BYT A;  4EAD A;  4N8Q A;  3QQS A;  4ZOJ A;  5BNE A;  1ZYK A;  4X59 A;  5EY3 A;  3QS8 A;  4X5A A;  3TWP A;  1AZY A;  5C7S A;  4X5E A;  4XR5 A;  4GA5 A;  4EAF A;  4GA6 A;  1VQU A;  4X5B A;  4YI7 A;  4X5C A;  4F3F C;  5EP8 A;  1BRW A;  1V8G A;  3QR9 A;  4IJ1 A;  4OWS A;  3H5Q A;  2ELC A;  2TPT A;  1O17 A;  4GIU A;  4ZOK A;  4YYY A;  4GKM A;  4OWM A;  2DSJ A;  4OWO A;  4X58 A;  4OWQ A;  3QSA A;  3R88 A;  3R6C A;  4OWV A;  1ZXY A;  4N5V A;  4X46 A;  2BPQ A;  4OWN A;  4MUO A;  4N93 A;  4GA4 A;  1KHD A;  3UU1 A;  1RF8 B;  5BO2 A;  1ZVW A;  4X5D A;  2WK5 A;  5C2L A;  4GTN A;  2GVQ A;  2J0F A;  1OTP A;  4ZTV A;  5BO3 A;  3GBR A;  4OWU A;  4YEK A;  4LHM A;  4HKM A; 
#chains in the Genus database with same CATH homology
 4GA6 A;  1RF8 B;  4F3F C;  4GA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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