4F3FC

Crystal structure of msln7-64 morab-009 fab complex
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
59
structure length
59
Chain Sequence
MCPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
pubmed doi rcsb
molecule keywords MORAb-009 Fab light chain
molecule tags Immune system
source organism Mus musculus
total genus 18
structure length 59
sequence length 59
ec nomenclature
pdb deposition date 2012-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.40 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 4f3fC00
4F3FC
chains in the Genus database with same CATH superfamily
1ZYKA 3QR9A 4EADA 5C7SA 1RF8B 4X5EA 1GXBA 4EAFA 2ELCA 4M0RA 3R88A 4GA6A 2WK6A 3GBRA 4GKMA 3R6CA 4X46A 4X5DA 4GA4A 4X58A 4OWOA 1ZVWA 5EP8A 4MUOA 4F3FC 4X5AA 1OTPA 4X5BA 2J0FA 1ZXYA 3H5QA 1V8GA 4ZOJA 4HKMA 4GIUA 2BPQA 3QQSA 4X59A 1AZYA 2WK5A 5BO3A 4X5CA 4ZOFA 4YEKA 1BRWA 5EY3A 5BNEA 4IJ1A 1VQUA 1O17A 4LHMA 3TWPA 4GTNA 3QS8A 3UU1A 4OWQA 5C1RA 2TPTA 4YI7A 4YYYA 2DSJA 5BO2A 1RRZA 1UOUA 3QSAA 4OWUA 4N8QA 1KHDA 4ZOKA 4GA5A 4XR5A 1KGZA 4OWNA 2GVQA 4N5VA 5C2LA 4OWSA 4OWVA 4ZTVA 5BYTA 4OWMA 4N93A
chains in the Genus database with same CATH topology
4GA6A 4F3FC 4GA5A 1RF8B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3F C; 
#chains in the Genus database with same CATH topology
 1ZYK A;  3QR9 A;  4EAD A;  5C7S A;  1RF8 B;  4X5E A;  1GXB A;  4EAF A;  2ELC A;  4M0R A;  3R88 A;  4GA6 A;  2WK6 A;  3GBR A;  4GKM A;  3R6C A;  4X46 A;  4X5D A;  4GA4 A;  4X58 A;  4OWO A;  1ZVW A;  5EP8 A;  4MUO A;  4F3F C;  4X5A A;  1OTP A;  4X5B A;  2J0F A;  1ZXY A;  3H5Q A;  1V8G A;  4ZOJ A;  4HKM A;  4GIU A;  2BPQ A;  3QQS A;  4X59 A;  1AZY A;  2WK5 A;  5BO3 A;  4X5C A;  4ZOF A;  4YEK A;  1BRW A;  5EY3 A;  5BNE A;  4IJ1 A;  1VQU A;  1O17 A;  4LHM A;  3TWP A;  4GTN A;  3QS8 A;  3UU1 A;  4OWQ A;  5C1R A;  2TPT A;  4YI7 A;  4YYY A;  2DSJ A;  5BO2 A;  1RRZ A;  1UOU A;  3QSA A;  4OWU A;  4N8Q A;  1KHD A;  4ZOK A;  4GA5 A;  4XR5 A;  1KGZ A;  4OWN A;  2GVQ A;  4N5V A;  5C2L A;  4OWS A;  4OWV A;  4ZTV A;  5BYT A;  4OWM A;  4N93 A; 
#chains in the Genus database with same CATH homology
 4GA6 A;  4F3F C;  4GA5 A;  1RF8 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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