4F3F | Genus

Total Genus 18

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	18
sequence length	59
structure length	59
Chain Sequence	MCPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDEL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 59 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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59 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights. pubmed doi rcsb
molecule keywords	MORAb-009 Fab light chain
molecule tags	Immune system
source organism	Mus musculus
total genus	18
structure length	59
sequence length	59
ec nomenclature
pdb deposition date	2012-05-09

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.970.40	Mainly Alpha	Up-down Bundle	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3	4f3fC00

4F3FC
chains in the Genus database with same CATH superfamily

4X58A 5EY3A 2ELCA 3QSAA 3H5QA 1RRZA 4X5DA 4OWOA 4YEKA 2WK5A 1KHDA 1O17A 4IJ1A 4OWMA 5EP8A 4XR5A 3TWPA 4GIUA 2J0FA 4ZOKA 2BPQA 4X59A 4N8QA 1ZVWA 3R6CA 1V8GA 3QQSA 4F3FC 5BNEA 4OWNA 1KGZA 4ZOJA 4X5CA 4X46A 1ZYKA 1VQUA 4X5EA 2TPTA 4X5AA 4ZOFA 5C2LA 4HKMA 1OTPA 4EAFA 1RF8B 4YYYA 4OWSA 2DSJA 4ZTVA 3GBRA 5C7SA 1GXBA 4GTNA 2WK6A 5C1RA 4OWUA 3QR9A 4M0RA 3QS8A 4EADA 1UOUA 4LHMA 3R88A 5BO2A 2GVQA 4OWVA 1BRWA 4GA5A 3UU1A 4N5VA 4GKMA 4MUOA 5BO3A 5BYTA 4OWQA 1AZYA 4N93A 4YI7A 1ZXYA 4GA6A 4GA4A 4X5BA
chains in the Genus database with same CATH topology

4GA5A 4F3FC 4GA6A 1RF8B
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4F3F C; 
#chains in the Genus database with same CATH topology
 4X58 A;  5EY3 A;  2ELC A;  3QSA A;  3H5Q A;  1RRZ A;  4X5D A;  4OWO A;  4YEK A;  2WK5 A;  1KHD A;  1O17 A;  4IJ1 A;  4OWM A;  5EP8 A;  4XR5 A;  3TWP A;  4GIU A;  2J0F A;  4ZOK A;  2BPQ A;  4X59 A;  4N8Q A;  1ZVW A;  3R6C A;  1V8G A;  3QQS A;  4F3F C;  5BNE A;  4OWN A;  1KGZ A;  4ZOJ A;  4X5C A;  4X46 A;  1ZYK A;  1VQU A;  4X5E A;  2TPT A;  4X5A A;  4ZOF A;  5C2L A;  4HKM A;  1OTP A;  4EAF A;  1RF8 B;  4YYY A;  4OWS A;  2DSJ A;  4ZTV A;  3GBR A;  5C7S A;  1GXB A;  4GTN A;  2WK6 A;  5C1R A;  4OWU A;  3QR9 A;  4M0R A;  3QS8 A;  4EAD A;  1UOU A;  4LHM A;  3R88 A;  5BO2 A;  2GVQ A;  4OWV A;  1BRW A;  4GA5 A;  3UU1 A;  4N5V A;  4GKM A;  4MUO A;  5BO3 A;  5BYT A;  4OWQ A;  1AZY A;  4N93 A;  4YI7 A;  1ZXY A;  4GA6 A;  4GA4 A;  4X5B A; 
#chains in the Genus database with same CATH homology
 4GA5 A;  4F3F C;  4GA6 A;  1RF8 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4F3FC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN