4F3FC

Crystal structure of msln7-64 morab-009 fab complex
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
59
structure length
59
Chain Sequence
MCPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
pubmed doi rcsb
molecule tags Immune system
source organism Mus musculus
molecule keywords MORAb-009 Fab light chain
total genus 18
structure length 59
sequence length 59
ec nomenclature
pdb deposition date 2012-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.40 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 4f3fC00
4F3FC
chains in the Genus database with same CATH superfamily
4F3FC 3H5QA 5BO3A 4M0RA 1O17A 4X59A 3QR9A 1KGZA 4GKMA 4YYYA 4YI7A 1AZYA 4LHMA 1VQUA 4X46A 4X5BA 2WK6A 3QQSA 2GVQA 4N5VA 2TPTA 3R88A 1V8GA 1ZXYA 5C7SA 4HKMA 5BNEA 4YEKA 4X5CA 2ELCA 5EP8A 4OWSA 3GBRA 4OWOA 4GA6A 4GA4A 1ZYKA 5BYTA 4OWMA 4EAFA 4X5DA 4N93A 4ZOKA 1RF8B 4N8QA 1ZVWA 5C2LA 2BPQA 4X5EA 4X5AA 3UU1A 1KHDA 3QSAA 1GXBA 4OWNA 1RRZA 4OWQA 4EADA 5EY3A 4XR5A 4GTNA 4IJ1A 4ZTVA 4OWVA 4ZOJA 3TWPA 2J0FA 4OWUA 5C1RA 4ZOFA 4GIUA 1OTPA 4MUOA 3QS8A 3R6CA 2WK5A 4X58A 1UOUA 2DSJA 5BO2A 4GA5A 1BRWA
chains in the Genus database with same CATH topology
4GA6A 1RF8B 4F3FC 4GA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3F C; 
#chains in the Genus database with same CATH topology
 4F3F C;  3H5Q A;  5BO3 A;  4M0R A;  1O17 A;  4X59 A;  3QR9 A;  1KGZ A;  4GKM A;  4YYY A;  4YI7 A;  1AZY A;  4LHM A;  1VQU A;  4X46 A;  4X5B A;  2WK6 A;  3QQS A;  2GVQ A;  4N5V A;  2TPT A;  3R88 A;  1V8G A;  1ZXY A;  5C7S A;  4HKM A;  5BNE A;  4YEK A;  4X5C A;  2ELC A;  5EP8 A;  4OWS A;  3GBR A;  4OWO A;  4GA6 A;  4GA4 A;  1ZYK A;  5BYT A;  4OWM A;  4EAF A;  4X5D A;  4N93 A;  4ZOK A;  1RF8 B;  4N8Q A;  1ZVW A;  5C2L A;  2BPQ A;  4X5E A;  4X5A A;  3UU1 A;  1KHD A;  3QSA A;  1GXB A;  4OWN A;  1RRZ A;  4OWQ A;  4EAD A;  5EY3 A;  4XR5 A;  4GTN A;  4IJ1 A;  4ZTV A;  4OWV A;  4ZOJ A;  3TWP A;  2J0F A;  4OWU A;  5C1R A;  4ZOF A;  4GIU A;  1OTP A;  4MUO A;  3QS8 A;  3R6C A;  2WK5 A;  4X58 A;  1UOU A;  2DSJ A;  5BO2 A;  4GA5 A;  1BRW A; 
#chains in the Genus database with same CATH homology
 4GA6 A;  1RF8 B;  4F3F C;  4GA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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