4OWVA

Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with anthranilate
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
350
structure length
343
Chain Sequence
SVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGTVNLSTMAAIVVAAAGVPVVKHGNRASLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQILE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Anthranilate phosphoribosyltransferase
total genus 121
structure length 343
sequence length 350
chains with identical sequence B
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2014-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 4owvA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 4owvA02
4OWOA 4GIUA 3R88A 1UOUA 4X58A 1VQUA 5BNEA 4ZOJA 1O17A 5EP8A 1OTPA 4GTNA 2WK5A 1KHDA 4IJ1A 3QR9A 4N93A 4EAFA 4XR5A 4OWQA 1ZYKA 1ZXYA 4ZTVA 3TWPA 4YYYA 1BRWA 4OWSA 3UU1A 2WK6A 3QQSA 2GVQA 4GKMA 4X5BA 4N8QA 1ZVWA 1AZYA 4X5DA 5BO3A 5C7SA 5EY3A 4X5EA 4EADA 4OWNA 4X5AA 3R6CA 5C1RA 1KGZA 2DSJA 4LHMA 2J0FA 4OWMA 4GA5A 4HKMA 4YI7A 4ZOFA 3H5QA 4X46A 4MUOA 3QS8A 1V8GA 3QSAA 2ELCA 3GBRA 5BYTA 4OWUA 4X59A 2BPQA 4N5VA 1GXBA 4ZOKA 4X5CA 4OWVA 2TPTA 5C2LA 4GA4A 5BO2A 4YEKA 4GA6A 4M0RA
chains in the Genus database with same CATH superfamily
4OWOA 4GIUA 3R88A 1UOUA 4X58A 1VQUA 5BNEA 4ZOJA 1O17A 5EP8A 1OTPA 4GTNA 2WK5A 1KHDA 4IJ1A 3QR9A 4N93A 4EAFA 4XR5A 4OWQA 1ZYKA 1ZXYA 4ZTVA 3TWPA 4YYYA 1BRWA 4OWSA 3UU1A 2WK6A 3QQSA 2GVQA 4GKMA 4X5BA 4N8QA 1ZVWA 1AZYA 4X5DA 5BO3A 5C7SA 5EY3A 1RRZA 4X5EA 4EADA 4OWNA 4X5AA 3R6CA 5C1RA 1KGZA 2DSJA 4LHMA 2J0FA 4OWMA 4GA5A 4HKMA 4YI7A 4ZOFA 3H5QA 4X46A 4MUOA 3QS8A 1V8GA 3QSAA 2ELCA 3GBRA 4F3FC 5BYTA 4OWUA 4X59A 1RF8B 2BPQA 4N5VA 1GXBA 4ZOKA 4X5CA 4OWVA 2TPTA 5C2LA 4GA4A 5BO2A 4YEKA 4GA6A 4M0RA
chains in the Genus database with same CATH topology
4OWOA 4GIUA 3R88A 1UOUA 4X58A 1VQUA 5BNEA 4ZOJA 1O17A 5EP8A 1OTPA 4GTNA 2WK5A 1KHDA 4IJ1A 3QR9A 4N93A 4EAFA 4XR5A 4OWQA 1ZYKA 1ZXYA 4ZTVA 3TWPA 4YYYA 1BRWA 4OWSA 3UU1A 2WK6A 3QQSA 2GVQA 4GKMA 4X5BA 4N8QA 1ZVWA 1AZYA 4X5DA 5BO3A 5C7SA 5EY3A 4X5EA 4EADA 4OWNA 4X5AA 3R6CA 5C1RA 1KGZA 2DSJA 4LHMA 2J0FA 4OWMA 4GA5A 4HKMA 4YI7A 4ZOFA 3H5QA 4X46A 4MUOA 3QS8A 1V8GA 3QSAA 2ELCA 3GBRA 5BYTA 4OWUA 4X59A 2BPQA 4N5VA 1GXBA 4ZOKA 4X5CA 4OWVA 2TPTA 5C2LA 4GA4A 5BO2A 4YEKA 4GA6A 4M0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OWO A;  4GIU A;  3R88 A;  1UOU A;  4X58 A;  1VQU A;  5BNE A;  4ZOJ A;  1O17 A;  5EP8 A;  1OTP A;  4GTN A;  2WK5 A;  1KHD A;  4IJ1 A;  3QR9 A;  4N93 A;  4EAF A;  4XR5 A;  4OWQ A;  1ZYK A;  1ZXY A;  4ZTV A;  3TWP A;  4YYY A;  1BRW A;  4OWS A;  3UU1 A;  2WK6 A;  3QQS A;  2GVQ A;  4GKM A;  4X5B A;  4N8Q A;  1ZVW A;  1AZY A;  4X5D A;  5BO3 A;  5C7S A;  5EY3 A;  4X5E A;  4EAD A;  4OWN A;  4X5A A;  3R6C A;  5C1R A;  1KGZ A;  2DSJ A;  4LHM A;  2J0F A;  4OWM A;  4GA5 A;  4HKM A;  4YI7 A;  4ZOF A;  3H5Q A;  4X46 A;  4MUO A;  3QS8 A;  1V8G A;  3QSA A;  2ELC A;  3GBR A;  5BYT A;  4OWU A;  4X59 A;  2BPQ A;  4N5V A;  1GXB A;  4ZOK A;  4X5C A;  4OWV A;  2TPT A;  5C2L A;  4GA4 A;  5BO2 A;  4YEK A;  4GA6 A;  4M0R A; 
#chains in the Genus database with same CATH topology
 4OWO A;  4GIU A;  3R88 A;  1UOU A;  4X58 A;  1VQU A;  5BNE A;  4ZOJ A;  1O17 A;  5EP8 A;  1OTP A;  4GTN A;  2WK5 A;  1KHD A;  4IJ1 A;  3QR9 A;  4N93 A;  4EAF A;  4XR5 A;  4OWQ A;  1ZYK A;  1ZXY A;  4ZTV A;  3TWP A;  4YYY A;  1BRW A;  4OWS A;  3UU1 A;  2WK6 A;  3QQS A;  2GVQ A;  4GKM A;  4X5B A;  4N8Q A;  1ZVW A;  1AZY A;  4X5D A;  5BO3 A;  5C7S A;  5EY3 A;  1RRZ A;  4X5E A;  4EAD A;  4OWN A;  4X5A A;  3R6C A;  5C1R A;  1KGZ A;  2DSJ A;  4LHM A;  2J0F A;  4OWM A;  4GA5 A;  4HKM A;  4YI7 A;  4ZOF A;  3H5Q A;  4X46 A;  4MUO A;  3QS8 A;  1V8G A;  3QSA A;  2ELC A;  3GBR A;  4F3F C;  5BYT A;  4OWU A;  4X59 A;  1RF8 B;  2BPQ A;  4N5V A;  1GXB A;  4ZOK A;  4X5C A;  4OWV A;  2TPT A;  5C2L A;  4GA4 A;  5BO2 A;  4YEK A;  4GA6 A;  4M0R A; 
#chains in the Genus database with same CATH homology
 4OWO A;  4GIU A;  3R88 A;  1UOU A;  4X58 A;  1VQU A;  5BNE A;  4ZOJ A;  1O17 A;  5EP8 A;  1OTP A;  4GTN A;  2WK5 A;  1KHD A;  4IJ1 A;  3QR9 A;  4N93 A;  4EAF A;  4XR5 A;  4OWQ A;  1ZYK A;  1ZXY A;  4ZTV A;  3TWP A;  4YYY A;  1BRW A;  4OWS A;  3UU1 A;  2WK6 A;  3QQS A;  2GVQ A;  4GKM A;  4X5B A;  4N8Q A;  1ZVW A;  1AZY A;  4X5D A;  5BO3 A;  5C7S A;  5EY3 A;  4X5E A;  4EAD A;  4OWN A;  4X5A A;  3R6C A;  5C1R A;  1KGZ A;  2DSJ A;  4LHM A;  2J0F A;  4OWM A;  4GA5 A;  4HKM A;  4YI7 A;  4ZOF A;  3H5Q A;  4X46 A;  4MUO A;  3QS8 A;  1V8G A;  3QSA A;  2ELC A;  3GBR A;  5BYT A;  4OWU A;  4X59 A;  2BPQ A;  4N5V A;  1GXB A;  4ZOK A;  4X5C A;  4OWV A;  2TPT A;  5C2L A;  4GA4 A;  5BO2 A;  4YEK A;  4GA6 A;  4M0R A; 
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