4BGKA

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with (3-(trimethylammonio)propyl)phosphinate
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
385
structure length
385
Chain Sequence
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords GAMMA-BUTYROBETAINE DIOXYGENASE
total genus 120
structure length 385
sequence length 385
ec nomenclature ec 1.14.11.1: Gamma-butyrobetaine dioxygenase.
pdb deposition date 2013-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02668 TauD Taurine catabolism dioxygenase TauD, TfdA family
A PF06155 DUF971 Protein of unknown function (DUF971)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2020.30 Alpha Beta 2-Layer Sandwich NE0471 N-terminal domain-like NE0471 N-terminal domain-like 4bgkA01
3.60.130.10 Alpha Beta 4-Layer Sandwich Double-stranded beta-helix Clavaminate synthase-like 4bgkA02
2Q4AA 2WBOA 1VZ5A 1GVGA 5HSXA 1OIIA 4M25A 4BGKA 1Y0ZA 4M23A 4M27A 3V15A 4M2CA 5KEUA 3MS5A 4M2FA 1OS7A 4C5WA 1NX4A 1DRTA 1GQWA 3O2GA 1JR7A 1NX8A 1VZ4A 2WBPA 4BHIA 1DS1A 1OIJB 4NE0A 4J5IA 2OG5A 4M2IA 3PVJA 1OIKA 2OG6A 2R6SA 4BGMA 4M2EA 5J92A 1DS0A 1OIJC 3V17A 3EATX 3LUUA 2OG7A 1OTJA 4M2GA 1OIJA 4BHFA 1GY9A 2WBQA 1OIHA 4BG1A 4C8RA 4FFAA 4YLMX 1DRYA 3R1JA 3SWTA 3N6WA 4M26A 4CWDA 4Y0EA 4OJ8A 4BHGA 4CVYA
chains in the Genus database with same CATH superfamily
2Q4AA 2WBOA 1VZ5A 1GVGA 5HSXA 1OIIA 4M25A 4BGKA 1Y0ZA 4M23A 4M27A 1PG6A 3V15A 4M2CA 5KEUA 3MS5A 4M2FA 2AUWA 1OS7A 4C5WA 1NX4A 2X8NA 1DRTA 1GQWA 3K8RA 3O2GA 1JR7A 1NX8A 1VZ4A 2WBPA 4BHIA 1DS1A 1OIJB 4NE0A 4J5IA 2OG5A 4M2IA 3PVJA 1OIKA 2OG6A 2R6SA 4BGMA 4M2EA 5J92A 1DS0A 1OIJC 3V17A 3EATX 3LUUA 2OG7A 1OTJA 4M2GA 1OIJA 4BHFA 1GY9A 2WBQA 1OIHA 4BG1A 4C8RA 4FFAA 4YLMX 1DRYA 3R1JA 3SWTA 3N6WA 4M26A 4CWDA 4Y0EA 1YOXA 4OJ8A 4BHGA 4CVYA
chains in the Genus database with same CATH topology
1GVGA 1OIIA 4BGKA 1MZEA 1Y0ZA 3V15A 4M2CA 5KEUA 3P3NA 1NX4A 1GQWA 3P3PA 4BHIA 4J5IA 5J92A 1H2NA 2OG7A 4AI8A 4Z1VA 4CWDA 2YDEA 4OJ8A 4BHGA 1JR7A 1NX8A 1OIJB 4NE0A 1IZ3A 3PVJA 1OIKA 4NR1A 3OD4A 2W0XA 4BGMA 1OIJC 3LUUA 2XUMA 4M2GA 2WA3A 4YLMX 1OIHA 5JWPA 1DRYA 3R1JA 3N6WA 4CVYA 1H2KA 4M25A 1H2MA 1H2LA 4M23A 3KCYA 4M27A 4BIOA 3D8CA 4JAAA 4M2FA 1OS7A 2ILMA 2X8NA 1DRTA 3KCXA 3K8RA 3O2GA 1YCIA 2YC0A 2Y0IA 2OG6A 2R6SA 4M2EA 1DS0A 3EATX 1OTJA 4BHFA 4BG1A 3SWTA 4B7KA 4Y0EA 2Q4AA 2WBOA 1VZ5A 5HSXA 3MS5A 1MZFA 4C5WA 4Z2WA 1VZ4A 2WBPA 2WA4A 1DS1A 2OG5A 4M2IA 2CGOA 3V17A 1OIJA 1GY9A 4B7EA 2WBQA 4FFAA 4C8RA 4M26A 2CGNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q4A A;  2WBO A;  1VZ5 A;  1GVG A;  5HSX A;  1OII A;  4M25 A;  4BGK A;  1Y0Z A;  4M23 A;  4M27 A;  3V15 A;  4M2C A;  5KEU A;  3MS5 A;  4M2F A;  1OS7 A;  4C5W A;  1NX4 A;  1DRT A;  1GQW A;  3O2G A;  1JR7 A;  1NX8 A;  1VZ4 A;  2WBP A;  4BHI A;  1DS1 A;  1OIJ B;  4NE0 A;  4J5I A;  2OG5 A;  4M2I A;  3PVJ A;  1OIK A;  2OG6 A;  2R6S A;  4BGM A;  4M2E A;  5J92 A;  1DS0 A;  1OIJ C;  3V17 A;  3EAT X;  3LUU A;  2OG7 A;  1OTJ A;  4M2G A;  1OIJ A;  4BHF A;  1GY9 A;  2WBQ A;  1OIH A;  4BG1 A;  4C8R A;  4FFA A;  4YLM X;  1DRY A;  3R1J A;  3SWT A;  3N6W A;  4M26 A;  4CWD A;  4Y0E A;  4OJ8 A;  4BHG A;  4CVY A; 
#chains in the Genus database with same CATH topology
 2Q4A A;  2WBO A;  1VZ5 A;  1GVG A;  5HSX A;  1OII A;  4M25 A;  4BGK A;  1Y0Z A;  4M23 A;  4M27 A;  1PG6 A;  3V15 A;  4M2C A;  5KEU A;  3MS5 A;  4M2F A;  2AUW A;  1OS7 A;  4C5W A;  1NX4 A;  2X8N A;  1DRT A;  1GQW A;  3K8R A;  3O2G A;  1JR7 A;  1NX8 A;  1VZ4 A;  2WBP A;  4BHI A;  1DS1 A;  1OIJ B;  4NE0 A;  4J5I A;  2OG5 A;  4M2I A;  3PVJ A;  1OIK A;  2OG6 A;  2R6S A;  4BGM A;  4M2E A;  5J92 A;  1DS0 A;  1OIJ C;  3V17 A;  3EAT X;  3LUU A;  2OG7 A;  1OTJ A;  4M2G A;  1OIJ A;  4BHF A;  1GY9 A;  2WBQ A;  1OIH A;  4BG1 A;  4C8R A;  4FFA A;  4YLM X;  1DRY A;  3R1J A;  3SWT A;  3N6W A;  4M26 A;  4CWD A;  4Y0E A;  1YOX A;  4OJ8 A;  4BHG A;  4CVY A; 
#chains in the Genus database with same CATH homology
 1GVG A;  1OII A;  4BGK A;  1MZE A;  1Y0Z A;  3V15 A;  4M2C A;  5KEU A;  3P3N A;  1NX4 A;  1GQW A;  3P3P A;  4BHI A;  4J5I A;  5J92 A;  1H2N A;  2OG7 A;  4AI8 A;  4Z1V A;  4CWD A;  2YDE A;  4OJ8 A;  4BHG A;  1JR7 A;  1NX8 A;  1OIJ B;  4NE0 A;  1IZ3 A;  3PVJ A;  1OIK A;  4NR1 A;  3OD4 A;  2W0X A;  4BGM A;  1OIJ C;  3LUU A;  2XUM A;  4M2G A;  2WA3 A;  4YLM X;  1OIH A;  5JWP A;  1DRY A;  3R1J A;  3N6W A;  4CVY A;  1H2K A;  4M25 A;  1H2M A;  1H2L A;  4M23 A;  3KCY A;  4M27 A;  4BIO A;  3D8C A;  4JAA A;  4M2F A;  1OS7 A;  2ILM A;  2X8N A;  1DRT A;  3KCX A;  3K8R A;  3O2G A;  1YCI A;  2YC0 A;  2Y0I A;  2OG6 A;  2R6S A;  4M2E A;  1DS0 A;  3EAT X;  1OTJ A;  4BHF A;  4BG1 A;  3SWT A;  4B7K A;  4Y0E A;  2Q4A A;  2WBO A;  1VZ5 A;  5HSX A;  3MS5 A;  1MZF A;  4C5W A;  4Z2W A;  1VZ4 A;  2WBP A;  2WA4 A;  1DS1 A;  2OG5 A;  4M2I A;  2CGO A;  3V17 A;  1OIJ A;  1GY9 A;  4B7E A;  2WBQ A;  4FFA A;  4C8R A;  4M26 A;  2CGN A; 
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