4BGMA

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 3-carboxy-n-(2-fluoroethyl)-n,n-dimethylpropan-1- aminium chloride
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
384
structure length
384
Chain Sequence
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords GAMMA-BUTYROBETAINE DIOXYGENASE
total genus 119
structure length 384
sequence length 384
ec nomenclature ec 1.14.11.1: Gamma-butyrobetaine dioxygenase.
pdb deposition date 2013-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02668 TauD Taurine catabolism dioxygenase TauD, TfdA family
A PF06155 DUF971 Protein of unknown function (DUF971)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2020.30 Alpha Beta 2-Layer Sandwich NE0471 N-terminal domain-like NE0471 N-terminal domain-like 4bgmA01
3.60.130.10 Alpha Beta 4-Layer Sandwich Double-stranded beta-helix Clavaminate synthase-like 4bgmA02
3MS5A 4C5WA 1JR7A 5KEUA 1OIKA 4M2FA 4BHGA 1DRTA 1Y0ZA 4BHIA 4Y0EA 4FFAA 1OIJA 2OG5A 4BHFA 2Q4AA 1DS0A 4YLMX 1OTJA 4CWDA 3O2GA 3R1JA 3LUUA 1DRYA 1VZ5A 4M2GA 1OIIA 4M27A 4OJ8A 4M23A 1VZ4A 4J5IA 1OIHA 3EATX 3N6WA 4BGMA 2OG7A 4BGKA 4CVYA 3PVJA 1OIJB 4C8RA 4M26A 1NX8A 2R6SA 3V17A 4M25A 4M2CA 4BG1A 1GQWA 1OIJC 2WBOA 4M2IA 2OG6A 2WBQA 3SWTA 1GVGA 1OS7A 3V15A 2WBPA 4NE0A 5J92A 1NX4A 1DS1A 1GY9A 4M2EA 5HSXA
chains in the Genus database with same CATH superfamily
3MS5A 3K8RA 4C5WA 1JR7A 1YOXA 5KEUA 1OIKA 4M2FA 4BHGA 1DRTA 1Y0ZA 4BHIA 4Y0EA 4FFAA 1OIJA 2X8NA 2OG5A 4BHFA 2AUWA 1DS0A 2Q4AA 1OTJA 4YLMX 4CWDA 3O2GA 3R1JA 3LUUA 1DRYA 1VZ5A 4M2GA 1OIIA 4M27A 4OJ8A 4M23A 1VZ4A 4J5IA 1OIHA 3EATX 3N6WA 4BGMA 2OG7A 4BGKA 4CVYA 3PVJA 1OIJB 4C8RA 4M26A 1NX8A 2R6SA 3V17A 4M25A 4M2CA 4BG1A 1GQWA 1OIJC 1PG6A 2WBOA 4M2IA 2OG6A 2WBQA 3SWTA 1GVGA 1OS7A 3V15A 2WBPA 4NE0A 5J92A 1NX4A 1DS1A 1GY9A 4M2EA 5HSXA
chains in the Genus database with same CATH topology
3MS5A 1DRTA 4FFAA 1H2MA 4BHFA 4AI8A 4BIOA 3EATX 3N6WA 4BGMA 2Y0IA 1NX8A 3OD4A 4M25A 3KCXA 2WBOA 3P3NA 2WBQA 1OS7A 1H2KA 1NX4A 1JR7A 1GY9A 4Y0EA 1IZ3A 5KEUA 1OIJA 4Z2WA 2OG5A 2Q4AA 1OTJA 4B7EA 1VZ5A 1OIIA 4M27A 1VZ4A 2WA3A 1H2LA 4CVYA 3PVJA 1OIJB 4C8RA 4M26A 2R6SA 4Z1VA 1OIJC 3V15A 2ILMA 4NE0A 1Y0ZA 3K8RA 4C5WA 4M2FA 4BHIA 1DS0A 3KCYA 2WA4A 3R1JA 1YCIA 3LUUA 1DRYA 4M2GA 4OJ8A 2YDEA 1MZEA 2OG7A 4JAAA 4BGKA 2CGNA 4B7KA 4M2CA 4BG1A 1GQWA 4M2IA 1DS1A 3P3PA 4M2EA 1OIKA 4BHGA 3D8CA 1H2NA 2X8NA 4YLMX 4CWDA 3O2GA 4M23A 2XUMA 4J5IA 1OIHA 5JWPA 2CGOA 2YC0A 3V17A 1MZFA 4NR1A 2OG6A 3SWTA 1GVGA 2W0XA 2WBPA 5J92A 5HSXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MS5 A;  4C5W A;  1JR7 A;  5KEU A;  1OIK A;  4M2F A;  4BHG A;  1DRT A;  1Y0Z A;  4BHI A;  4Y0E A;  4FFA A;  1OIJ A;  2OG5 A;  4BHF A;  2Q4A A;  1DS0 A;  4YLM X;  1OTJ A;  4CWD A;  3O2G A;  3R1J A;  3LUU A;  1DRY A;  1VZ5 A;  4M2G A;  1OII A;  4M27 A;  4OJ8 A;  4M23 A;  1VZ4 A;  4J5I A;  1OIH A;  3EAT X;  3N6W A;  4BGM A;  2OG7 A;  4BGK A;  4CVY A;  3PVJ A;  1OIJ B;  4C8R A;  4M26 A;  1NX8 A;  2R6S A;  3V17 A;  4M25 A;  4M2C A;  4BG1 A;  1GQW A;  1OIJ C;  2WBO A;  4M2I A;  2OG6 A;  2WBQ A;  3SWT A;  1GVG A;  1OS7 A;  3V15 A;  2WBP A;  4NE0 A;  5J92 A;  1NX4 A;  1DS1 A;  1GY9 A;  4M2E A;  5HSX A; 
#chains in the Genus database with same CATH topology
 3MS5 A;  3K8R A;  4C5W A;  1JR7 A;  1YOX A;  5KEU A;  1OIK A;  4M2F A;  4BHG A;  1DRT A;  1Y0Z A;  4BHI A;  4Y0E A;  4FFA A;  1OIJ A;  2X8N A;  2OG5 A;  4BHF A;  2AUW A;  1DS0 A;  2Q4A A;  1OTJ A;  4YLM X;  4CWD A;  3O2G A;  3R1J A;  3LUU A;  1DRY A;  1VZ5 A;  4M2G A;  1OII A;  4M27 A;  4OJ8 A;  4M23 A;  1VZ4 A;  4J5I A;  1OIH A;  3EAT X;  3N6W A;  4BGM A;  2OG7 A;  4BGK A;  4CVY A;  3PVJ A;  1OIJ B;  4C8R A;  4M26 A;  1NX8 A;  2R6S A;  3V17 A;  4M25 A;  4M2C A;  4BG1 A;  1GQW A;  1OIJ C;  1PG6 A;  2WBO A;  4M2I A;  2OG6 A;  2WBQ A;  3SWT A;  1GVG A;  1OS7 A;  3V15 A;  2WBP A;  4NE0 A;  5J92 A;  1NX4 A;  1DS1 A;  1GY9 A;  4M2E A;  5HSX A; 
#chains in the Genus database with same CATH homology
 3MS5 A;  1DRT A;  4FFA A;  1H2M A;  4BHF A;  4AI8 A;  4BIO A;  3EAT X;  3N6W A;  4BGM A;  2Y0I A;  1NX8 A;  3OD4 A;  4M25 A;  3KCX A;  2WBO A;  3P3N A;  2WBQ A;  1OS7 A;  1H2K A;  1NX4 A;  1JR7 A;  1GY9 A;  4Y0E A;  1IZ3 A;  5KEU A;  1OIJ A;  4Z2W A;  2OG5 A;  2Q4A A;  1OTJ A;  4B7E A;  1VZ5 A;  1OII A;  4M27 A;  1VZ4 A;  2WA3 A;  1H2L A;  4CVY A;  3PVJ A;  1OIJ B;  4C8R A;  4M26 A;  2R6S A;  4Z1V A;  1OIJ C;  3V15 A;  2ILM A;  4NE0 A;  1Y0Z A;  3K8R A;  4C5W A;  4M2F A;  4BHI A;  1DS0 A;  3KCY A;  2WA4 A;  3R1J A;  1YCI A;  3LUU A;  1DRY A;  4M2G A;  4OJ8 A;  2YDE A;  1MZE A;  2OG7 A;  4JAA A;  4BGK A;  2CGN A;  4B7K A;  4M2C A;  4BG1 A;  1GQW A;  4M2I A;  1DS1 A;  3P3P A;  4M2E A;  1OIK A;  4BHG A;  3D8C A;  1H2N A;  2X8N A;  4YLM X;  4CWD A;  3O2G A;  4M23 A;  2XUM A;  4J5I A;  1OIH A;  5JWP A;  2CGO A;  2YC0 A;  3V17 A;  1MZF A;  4NR1 A;  2OG6 A;  3SWT A;  1GVG A;  2W0X A;  2WBP A;  5J92 A;  5HSX A; 
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