5C2LA

Magnesium soaked into the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
Total Genus 123
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
349
structure length
349
Chain Sequence
SVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase
source organism Mycobacterium tuberculosis
publication title Binding and mimicking of the phosphate-rich substrate, PRPP
rcsb
molecule keywords Anthranilate phosphoribosyltransferase
total genus 123
structure length 349
sequence length 349
chains with identical sequence B
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 5c2lA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 5c2lA02
4IJ1A 3QSAA 4YI7A 3GBRA 4OWMA 4ZTVA 3R88A 1GXBA 3H5QA 3QQSA 4X5DA 4OWVA 5EY3A 4M0RA 5C7SA 2TPTA 2ELCA 4X5EA 2BPQA 5BYTA 4N8QA 4LHMA 4X46A 2DSJA 4GKMA 1UOUA 4N5VA 4XR5A 5BNEA 4EADA 5EP8A 4GA6A 4ZOKA 4ZOFA 1KHDA 4OWNA 1ZYKA 1BRWA 4GIUA 5C2LA 5BO2A 3TWPA 2J0FA 4GA5A 1OTPA 1VQUA 3QR9A 1AZYA 4X5BA 4OWUA 1KGZA 1ZVWA 3UU1A 4X59A 4X5CA 5C1RA 4OWQA 2GVQA 4GTNA 1O17A 4ZOJA 1ZXYA 3R6CA 4YEKA 4OWSA 4YYYA 4MUOA 4EAFA 4GA4A 2WK5A 3QS8A 4X5AA 5BO3A 4HKMA 4X58A 4OWOA 2WK6A 1V8GA 4N93A
chains in the Genus database with same CATH superfamily
4IJ1A 3QSAA 4YI7A 3GBRA 4OWMA 4ZTVA 3R88A 1GXBA 3H5QA 3QQSA 4X5DA 4OWVA 5EY3A 4M0RA 5C7SA 2TPTA 2ELCA 4X5EA 2BPQA 5BYTA 4N8QA 4LHMA 4X46A 2DSJA 4GKMA 1UOUA 4N5VA 4XR5A 5BNEA 4EADA 4GA6A 5EP8A 4ZOKA 4ZOFA 1KHDA 4OWNA 1ZYKA 1BRWA 4GIUA 5C2LA 5BO2A 3TWPA 2J0FA 4GA5A 1OTPA 1VQUA 3QR9A 1AZYA 4X5BA 4OWUA 1KGZA 1ZVWA 3UU1A 4X59A 4X5CA 5C1RA 4OWQA 2GVQA 4GTNA 1O17A 4ZOJA 4F3FC 1ZXYA 3R6CA 4YEKA 4OWSA 4YYYA 4MUOA 4EAFA 4GA4A 1RF8B 2WK5A 3QS8A 4X5AA 1RRZA 5BO3A 4HKMA 4X58A 4OWOA 2WK6A 1V8GA 4N93A
chains in the Genus database with same CATH topology
4IJ1A 3QSAA 4YI7A 3GBRA 4OWMA 4ZTVA 3R88A 1GXBA 3H5QA 3QQSA 4X5DA 4OWVA 5EY3A 4M0RA 5C7SA 2TPTA 2ELCA 4X5EA 2BPQA 5BYTA 4N8QA 4LHMA 4X46A 2DSJA 4GKMA 1UOUA 4N5VA 4XR5A 5BNEA 4EADA 5EP8A 4GA6A 4ZOKA 4ZOFA 1KHDA 4OWNA 1ZYKA 1BRWA 4GIUA 5C2LA 5BO2A 3TWPA 2J0FA 4GA5A 1OTPA 1VQUA 3QR9A 1AZYA 4X5BA 4OWUA 1KGZA 1ZVWA 3UU1A 4X59A 4X5CA 5C1RA 4OWQA 2GVQA 4GTNA 1O17A 4ZOJA 1ZXYA 3R6CA 4YEKA 4OWSA 4YYYA 4MUOA 4EAFA 4GA4A 2WK5A 3QS8A 4X5AA 5BO3A 4HKMA 4X58A 4OWOA 2WK6A 1V8GA 4N93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IJ1 A;  3QSA A;  4YI7 A;  3GBR A;  4OWM A;  4ZTV A;  3R88 A;  1GXB A;  3H5Q A;  3QQS A;  4X5D A;  4OWV A;  5EY3 A;  4M0R A;  5C7S A;  2TPT A;  2ELC A;  4X5E A;  2BPQ A;  5BYT A;  4N8Q A;  4LHM A;  4X46 A;  2DSJ A;  4GKM A;  1UOU A;  4N5V A;  4XR5 A;  5BNE A;  4EAD A;  5EP8 A;  4GA6 A;  4ZOK A;  4ZOF A;  1KHD A;  4OWN A;  1ZYK A;  1BRW A;  4GIU A;  5C2L A;  5BO2 A;  3TWP A;  2J0F A;  4GA5 A;  1OTP A;  1VQU A;  3QR9 A;  1AZY A;  4X5B A;  4OWU A;  1KGZ A;  1ZVW A;  3UU1 A;  4X59 A;  4X5C A;  5C1R A;  4OWQ A;  2GVQ A;  4GTN A;  1O17 A;  4ZOJ A;  1ZXY A;  3R6C A;  4YEK A;  4OWS A;  4YYY A;  4MUO A;  4EAF A;  4GA4 A;  2WK5 A;  3QS8 A;  4X5A A;  5BO3 A;  4HKM A;  4X58 A;  4OWO A;  2WK6 A;  1V8G A;  4N93 A; 
#chains in the Genus database with same CATH topology
 4IJ1 A;  3QSA A;  4YI7 A;  3GBR A;  4OWM A;  4ZTV A;  3R88 A;  1GXB A;  3H5Q A;  3QQS A;  4X5D A;  4OWV A;  5EY3 A;  4M0R A;  5C7S A;  2TPT A;  2ELC A;  4X5E A;  2BPQ A;  5BYT A;  4N8Q A;  4LHM A;  4X46 A;  2DSJ A;  4GKM A;  1UOU A;  4N5V A;  4XR5 A;  5BNE A;  4EAD A;  4GA6 A;  5EP8 A;  4ZOK A;  4ZOF A;  1KHD A;  4OWN A;  1ZYK A;  1BRW A;  4GIU A;  5C2L A;  5BO2 A;  3TWP A;  2J0F A;  4GA5 A;  1OTP A;  1VQU A;  3QR9 A;  1AZY A;  4X5B A;  4OWU A;  1KGZ A;  1ZVW A;  3UU1 A;  4X59 A;  4X5C A;  5C1R A;  4OWQ A;  2GVQ A;  4GTN A;  1O17 A;  4ZOJ A;  4F3F C;  1ZXY A;  3R6C A;  4YEK A;  4OWS A;  4YYY A;  4MUO A;  4EAF A;  4GA4 A;  1RF8 B;  2WK5 A;  3QS8 A;  4X5A A;  1RRZ A;  5BO3 A;  4HKM A;  4X58 A;  4OWO A;  2WK6 A;  1V8G A;  4N93 A; 
#chains in the Genus database with same CATH homology
 4IJ1 A;  3QSA A;  4YI7 A;  3GBR A;  4OWM A;  4ZTV A;  3R88 A;  1GXB A;  3H5Q A;  3QQS A;  4X5D A;  4OWV A;  5EY3 A;  4M0R A;  5C7S A;  2TPT A;  2ELC A;  4X5E A;  2BPQ A;  5BYT A;  4N8Q A;  4LHM A;  4X46 A;  2DSJ A;  4GKM A;  1UOU A;  4N5V A;  4XR5 A;  5BNE A;  4EAD A;  5EP8 A;  4GA6 A;  4ZOK A;  4ZOF A;  1KHD A;  4OWN A;  1ZYK A;  1BRW A;  4GIU A;  5C2L A;  5BO2 A;  3TWP A;  2J0F A;  4GA5 A;  1OTP A;  1VQU A;  3QR9 A;  1AZY A;  4X5B A;  4OWU A;  1KGZ A;  1ZVW A;  3UU1 A;  4X59 A;  4X5C A;  5C1R A;  4OWQ A;  2GVQ A;  4GTN A;  1O17 A;  4ZOJ A;  1ZXY A;  3R6C A;  4YEK A;  4OWS A;  4YYY A;  4MUO A;  4EAF A;  4GA4 A;  2WK5 A;  3QS8 A;  4X5A A;  5BO3 A;  4HKM A;  4X58 A;  4OWO A;  2WK6 A;  1V8G A;  4N93 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...