1YO7A

Re-engineering topology of the homodimeric rop protein into a single-chain 4-helix bundle
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
120
structure length
120
Chain Sequence
MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDHADELYRSCLASFKKNGQIDEQADICESLHDHADELYRSCLARFGGSKQEKTALNMARFIRSQTLTLLEKLNELAKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle.
rcsb
molecule tags Replication regulator
source organism Escherichia coli
molecule keywords Regulatory protein rop
total genus 55
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01815 Rop Rop protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.10 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 1yo7A00
1YO7A 1SJ8A
chains in the Genus database with same CATH superfamily
4OAVB 2A2CA 2L1LB 4NV5A 4PL5A 4GXTA 4O1PA 2V1CC 3LJ2A 4Q9VA 3I9V1 2F66B 2ZRRA 2XMXA 4OAUC 4HFVA 2FEFA 2BL7A 4I1TA 2CAZB 2QSBA 4DWLA 4YZDA 2BL8A 2FUG1 3B55A 2JB2A 4G75A 2JB1A 3VA9A 1U5KA 3P23A 4NV2A 5HGIA 5LNK1 2JAEA 2FU2A 2IP6A 3AJFA 3IAS1 2GSCA 3F4MA 4HEA1 4YZ9A 2K19A 2XTQA 4Z7GA 2HGKA 3LJ0A 4PL3A 3DA4A 4AS3A 4YZCA 2V6EA 4AS2A 4Z7HA 1W3SA 3IAM1 4JCVE 1SJ8A 3SDJA 3LJ1A 4O1OA 4G76A 4U6RA 2JBWA 2KKMA 2RADA 1JQOA 2YFAA 3UITA 2QZGA 3L0IA 3DO9A 1YO7A 2XTRA 2YFBA 3DA3A 1TDPA 2ZW3A 2F6MB 3FBVA 3FNBA 2A2DA 2ETDA 4PL4A 3JSBA 2QGMA 3KP9A 2RLDA 2JB3A 2RIOA 3FVVA 2P22B 2MJFB 2E8GA 3Q8DA
chains in the Genus database with same CATH topology
4OAVB 2A2CA 2L1LB 4NV5A 4PL5A 4GXTA 4O1PA 2V1CC 3LJ2A 4Q9VA 3I9V1 2F66B 2ZRRA 2XMXA 4OAUC 4HFVA 4I1TA 2CAZB 4DWLA 4YZDA 2FUG1 2JB2A 4G75A 2JB1A 3VA9A 1U5KA 3P23A 4NV2A 5HGIA 5LNK1 2JAEA 2IP6A 3AJFA 3IAS1 3F4MA 4HEA1 4YZ9A 2K19A 2XTQA 4Z7GA 3LJ0A 4PL3A 3DA4A 4AS3A 4YZCA 2V6EA 4AS2A 4Z7HA 1W3SA 3IAM1 4JCVE 1SJ8A 3SDJA 3LJ1A 4O1OA 4G76A 4U6RA 2KKMA 2YFAA 3UITA 3L0IA 3DO9A 1YO7A 2XTRA 2YFBA 3DA3A 2F6MB 3FBVA 2A2DA 4PL4A 3JSBA 3KP9A 2JB3A 2RIOA 2P22B 2MJFB 2E8GA 3Q8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YO7 A;  1SJ8 A; 
#chains in the Genus database with same CATH topology
 4OAV B;  2A2C A;  2L1L B;  4NV5 A;  4PL5 A;  4GXT A;  4O1P A;  2V1C C;  3LJ2 A;  4Q9V A;  3I9V 1;  2F66 B;  2ZRR A;  2XMX A;  4OAU C;  4HFV A;  2FEF A;  2BL7 A;  4I1T A;  2CAZ B;  2QSB A;  4DWL A;  4YZD A;  2BL8 A;  2FUG 1;  3B55 A;  2JB2 A;  4G75 A;  2JB1 A;  3VA9 A;  1U5K A;  3P23 A;  4NV2 A;  5HGI A;  5LNK 1;  2JAE A;  2FU2 A;  2IP6 A;  3AJF A;  3IAS 1;  2GSC A;  3F4M A;  4HEA 1;  4YZ9 A;  2K19 A;  2XTQ A;  4Z7G A;  2HGK A;  3LJ0 A;  4PL3 A;  3DA4 A;  4AS3 A;  4YZC A;  2V6E A;  4AS2 A;  4Z7H A;  1W3S A;  3IAM 1;  4JCV E;  1SJ8 A;  3SDJ A;  3LJ1 A;  4O1O A;  4G76 A;  4U6R A;  2JBW A;  2KKM A;  2RAD A;  1JQO A;  2YFA A;  3UIT A;  2QZG A;  3L0I A;  3DO9 A;  1YO7 A;  2XTR A;  2YFB A;  3DA3 A;  1TDP A;  2ZW3 A;  2F6M B;  3FBV A;  3FNB A;  2A2D A;  2ETD A;  4PL4 A;  3JSB A;  2QGM A;  3KP9 A;  2RLD A;  2JB3 A;  2RIO A;  3FVV A;  2P22 B;  2MJF B;  2E8G A;  3Q8D A; 
#chains in the Genus database with same CATH homology
 4OAV B;  2A2C A;  2L1L B;  4NV5 A;  4PL5 A;  4GXT A;  4O1P A;  2V1C C;  3LJ2 A;  4Q9V A;  3I9V 1;  2F66 B;  2ZRR A;  2XMX A;  4OAU C;  4HFV A;  4I1T A;  2CAZ B;  4DWL A;  4YZD A;  2FUG 1;  2JB2 A;  4G75 A;  2JB1 A;  3VA9 A;  1U5K A;  3P23 A;  4NV2 A;  5HGI A;  5LNK 1;  2JAE A;  2IP6 A;  3AJF A;  3IAS 1;  3F4M A;  4HEA 1;  4YZ9 A;  2K19 A;  2XTQ A;  4Z7G A;  3LJ0 A;  4PL3 A;  3DA4 A;  4AS3 A;  4YZC A;  2V6E A;  4AS2 A;  4Z7H A;  1W3S A;  3IAM 1;  4JCV E;  1SJ8 A;  3SDJ A;  3LJ1 A;  4O1O A;  4G76 A;  4U6R A;  2KKM A;  2YFA A;  3UIT A;  3L0I A;  3DO9 A;  1YO7 A;  2XTR A;  2YFB A;  3DA3 A;  2F6M B;  3FBV A;  2A2D A;  4PL4 A;  3JSB A;  3KP9 A;  2JB3 A;  2RIO A;  2P22 B;  2MJF B;  2E8G A;  3Q8D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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