2CAZB

Escrt-i core
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
100
structure length
100
Chain Sequence
PLFDNSITSKDKEVIETLSEIYSIVITLDHVEKAYLKDSIDDTQYTNTVDKLLKQFKVYLNSQNKEEINKHFQSIEAFCDTYNITASNAITRLERGIPIT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Escrt-I Core and Escrt-II Glue Domain Structures Reveal Role for Glue in Linking to Escrt-I and Membranes.
pubmed doi rcsb
molecule tags Protein transport
source organism Saccharomyces cerevisiae
molecule keywords SUPPRESSOR PROTEIN STP22 OF TEMPERATURE-SENSITIVE ALPHA-FACT
total genus 32
structure length 100
sequence length 100
chains with identical sequence E
ec nomenclature
pdb deposition date 2005-12-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.200 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 2cazB00
2P22B 2F66B 2CAZB 2F6MB
chains in the Genus database with same CATH superfamily
3P23A 2HGKA 4I1TA 3I9V1 3Q8DA 4NV5A 2L1LB 2JBWA 2QSBA 4Z7HA 2FUG1 4YZDA 2ETDA 3FNBA 4AS3A 4DWLA 2RADA 3AJFA 4YZ9A 2JB1A 2XTQA 4Z7GA 2BL8A 3DA4A 3VA9A 4O1OA 2FU2A 2A2CA 4GXTA 2A2DA 2RIOA 2P22B 2F66B 1JQOA 2ZRRA 3SDJA 2RLDA 3LJ0A 2CAZB 2V1CC 4Q9VA 3FBVA 2YFBA 4G75A 2E8GA 3LJ2A 3UITA 2XMXA 3KP9A 1YO7A 1W3SA 4OAVB 2BL7A 5LNK1 2K19A 4O1PA 2GSCA 3LJ1A 3JSBA 1TDPA 4NV2A 2XTRA 3F4MA 2QZGA 4PL4A 4PL5A 1SJ8A 4U6RA 3DO9A 3B55A 3IAM1 4G76A 2JB2A 4HFVA 2F6MB 4PL3A 2QGMA 3FVVA 2FEFA 4HEA1 2YFAA 3L0IA 2MJFB 5HGIA 2IP6A 2ZW3A 4YZCA 3DA3A 2JB3A 2KKMA 4AS2A 3IAS1 1U5KA 2V6EA 4JCVE 4OAUC 2JAEA
chains in the Genus database with same CATH topology
3P23A 4I1TA 3I9V1 3Q8DA 4NV5A 2L1LB 4Z7HA 2FUG1 4YZDA 4AS3A 4DWLA 3AJFA 4YZ9A 2JB1A 2XTQA 4Z7GA 3DA4A 3VA9A 4O1OA 2A2CA 4GXTA 2A2DA 2RIOA 2P22B 2F66B 2ZRRA 3SDJA 3LJ0A 2CAZB 2V1CC 4Q9VA 3FBVA 2YFBA 4G75A 2E8GA 3LJ2A 3UITA 2XMXA 3KP9A 1YO7A 1W3SA 4OAVB 5LNK1 2K19A 4O1PA 3LJ1A 3JSBA 4NV2A 2XTRA 3F4MA 4PL4A 4PL5A 1SJ8A 4U6RA 3DO9A 3IAM1 4G76A 2JB2A 4HFVA 2F6MB 4PL3A 4HEA1 2YFAA 3L0IA 2MJFB 5HGIA 2IP6A 4YZCA 3DA3A 2JB3A 2KKMA 4AS2A 3IAS1 1U5KA 2V6EA 4JCVE 4OAUC 2JAEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P22 B;  2F66 B;  2CAZ B;  2F6M B; 
#chains in the Genus database with same CATH topology
 3P23 A;  2HGK A;  4I1T A;  3I9V 1;  3Q8D A;  4NV5 A;  2L1L B;  2JBW A;  2QSB A;  4Z7H A;  2FUG 1;  4YZD A;  2ETD A;  3FNB A;  4AS3 A;  4DWL A;  2RAD A;  3AJF A;  4YZ9 A;  2JB1 A;  2XTQ A;  4Z7G A;  2BL8 A;  3DA4 A;  3VA9 A;  4O1O A;  2FU2 A;  2A2C A;  4GXT A;  2A2D A;  2RIO A;  2P22 B;  2F66 B;  1JQO A;  2ZRR A;  3SDJ A;  2RLD A;  3LJ0 A;  2CAZ B;  2V1C C;  4Q9V A;  3FBV A;  2YFB A;  4G75 A;  2E8G A;  3LJ2 A;  3UIT A;  2XMX A;  3KP9 A;  1YO7 A;  1W3S A;  4OAV B;  2BL7 A;  5LNK 1;  2K19 A;  4O1P A;  2GSC A;  3LJ1 A;  3JSB A;  1TDP A;  4NV2 A;  2XTR A;  3F4M A;  2QZG A;  4PL4 A;  4PL5 A;  1SJ8 A;  4U6R A;  3DO9 A;  3B55 A;  3IAM 1;  4G76 A;  2JB2 A;  4HFV A;  2F6M B;  4PL3 A;  2QGM A;  3FVV A;  2FEF A;  4HEA 1;  2YFA A;  3L0I A;  2MJF B;  5HGI A;  2IP6 A;  2ZW3 A;  4YZC A;  3DA3 A;  2JB3 A;  2KKM A;  4AS2 A;  3IAS 1;  1U5K A;  2V6E A;  4JCV E;  4OAU C;  2JAE A; 
#chains in the Genus database with same CATH homology
 3P23 A;  4I1T A;  3I9V 1;  3Q8D A;  4NV5 A;  2L1L B;  4Z7H A;  2FUG 1;  4YZD A;  4AS3 A;  4DWL A;  3AJF A;  4YZ9 A;  2JB1 A;  2XTQ A;  4Z7G A;  3DA4 A;  3VA9 A;  4O1O A;  2A2C A;  4GXT A;  2A2D A;  2RIO A;  2P22 B;  2F66 B;  2ZRR A;  3SDJ A;  3LJ0 A;  2CAZ B;  2V1C C;  4Q9V A;  3FBV A;  2YFB A;  4G75 A;  2E8G A;  3LJ2 A;  3UIT A;  2XMX A;  3KP9 A;  1YO7 A;  1W3S A;  4OAV B;  5LNK 1;  2K19 A;  4O1P A;  3LJ1 A;  3JSB A;  4NV2 A;  2XTR A;  3F4M A;  4PL4 A;  4PL5 A;  1SJ8 A;  4U6R A;  3DO9 A;  3IAM 1;  4G76 A;  2JB2 A;  4HFV A;  2F6M B;  4PL3 A;  4HEA 1;  2YFA A;  3L0I A;  2MJF B;  5HGI A;  2IP6 A;  4YZC A;  3DA3 A;  2JB3 A;  2KKM A;  4AS2 A;  3IAS 1;  1U5K A;  2V6E A;  4JCV E;  4OAU C;  2JAE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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