2L1LB

Nmr solution structure of the phi0 pki nes peptide in complex with crm1-rangtp
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
127
structure length
127
Chain Sequence
ISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
pubmed doi rcsb
molecule tags Nuclear protein
source organism Homo sapiens
molecule keywords cAMP-dependent protein kinase inhibitor alpha
total genus 39
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2010-07-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.250 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 2l1lB00
2L1LB
chains in the Genus database with same CATH superfamily
4PL4A 2IP6A 3UITA 2XTRA 5HGIA 4JCVE 3FNBA 3JSBA 2E8GA 2YFBA 2JB2A 2RLDA 4O1OA 3KP9A 4G76A 2K19A 4YZ9A 2QZGA 2JB1A 4AS2A 4Z7GA 2KKMA 2F66B 4I1TA 3P23A 1YO7A 5LNK1 2JBWA 2MJFB 2BL8A 2JB3A 2JAEA 2A2CA 2RADA 3AJFA 1W3SA 1TDPA 3L0IA 3SDJA 2FEFA 4HEA1 4O1PA 3FBVA 2A2DA 3I9V1 3B55A 4GXTA 4PL5A 2BL7A 3VA9A 2V6EA 2FU2A 2L1LB 4OAVB 2P22B 4G75A 4YZCA 4HFVA 3DA4A 3LJ1A 4PL3A 3IAM1 4NV5A 3Q8DA 2ZW3A 3DO9A 4YZDA 1U5KA 1SJ8A 2V1CC 3IAS1 2ETDA 3LJ0A 3DA3A 2FUG1 2HGKA 4Z7HA 2F6MB 2CAZB 4OAUC 2RIOA 3F4MA 2XMXA 3LJ2A 2XTQA 3FVVA 2GSCA 4U6RA 4Q9VA 1JQOA 2ZRRA 2QSBA 4AS3A 4DWLA 4NV2A 2QGMA 2YFAA
chains in the Genus database with same CATH topology
4PL4A 2IP6A 3UITA 2XTRA 5HGIA 2YFAA 4JCVE 3JSBA 2E8GA 2YFBA 2JB2A 4O1OA 3KP9A 4G76A 2K19A 2JB1A 4AS2A 4Z7GA 2KKMA 2F66B 4I1TA 3P23A 1YO7A 5LNK1 2MJFB 2JB3A 2JAEA 2A2CA 3AJFA 1W3SA 3L0IA 3SDJA 4HEA1 4O1PA 3FBVA 2A2DA 3I9V1 4GXTA 4PL5A 3VA9A 2V6EA 2L1LB 4OAVB 2P22B 4YZCA 4G75A 4HFVA 3DA4A 3LJ1A 4PL3A 3IAM1 4NV5A 3Q8DA 3DO9A 4YZDA 1U5KA 1SJ8A 2V1CC 3IAS1 3LJ0A 3DA3A 2FUG1 4Z7HA 2F6MB 2CAZB 4OAUC 2RIOA 3F4MA 2XMXA 3LJ2A 2XTQA 4U6RA 4Q9VA 2ZRRA 4AS3A 4DWLA 4NV2A 4YZ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L1L B; 
#chains in the Genus database with same CATH topology
 4PL4 A;  2IP6 A;  3UIT A;  2XTR A;  5HGI A;  4JCV E;  3FNB A;  3JSB A;  2E8G A;  2YFB A;  2JB2 A;  2RLD A;  4O1O A;  3KP9 A;  4G76 A;  2K19 A;  4YZ9 A;  2QZG A;  2JB1 A;  4AS2 A;  4Z7G A;  2KKM A;  2F66 B;  4I1T A;  3P23 A;  1YO7 A;  5LNK 1;  2JBW A;  2MJF B;  2BL8 A;  2JB3 A;  2JAE A;  2A2C A;  2RAD A;  3AJF A;  1W3S A;  1TDP A;  3L0I A;  3SDJ A;  2FEF A;  4HEA 1;  4O1P A;  3FBV A;  2A2D A;  3I9V 1;  3B55 A;  4GXT A;  4PL5 A;  2BL7 A;  3VA9 A;  2V6E A;  2FU2 A;  2L1L B;  4OAV B;  2P22 B;  4G75 A;  4YZC A;  4HFV A;  3DA4 A;  3LJ1 A;  4PL3 A;  3IAM 1;  4NV5 A;  3Q8D A;  2ZW3 A;  3DO9 A;  4YZD A;  1U5K A;  1SJ8 A;  2V1C C;  3IAS 1;  2ETD A;  3LJ0 A;  3DA3 A;  2FUG 1;  2HGK A;  4Z7H A;  2F6M B;  2CAZ B;  4OAU C;  2RIO A;  3F4M A;  2XMX A;  3LJ2 A;  2XTQ A;  3FVV A;  2GSC A;  4U6R A;  4Q9V A;  1JQO A;  2ZRR A;  2QSB A;  4AS3 A;  4DWL A;  4NV2 A;  2QGM A;  2YFA A; 
#chains in the Genus database with same CATH homology
 4PL4 A;  2IP6 A;  3UIT A;  2XTR A;  5HGI A;  2YFA A;  4JCV E;  3JSB A;  2E8G A;  2YFB A;  2JB2 A;  4O1O A;  3KP9 A;  4G76 A;  2K19 A;  2JB1 A;  4AS2 A;  4Z7G A;  2KKM A;  2F66 B;  4I1T A;  3P23 A;  1YO7 A;  5LNK 1;  2MJF B;  2JB3 A;  2JAE A;  2A2C A;  3AJF A;  1W3S A;  3L0I A;  3SDJ A;  4HEA 1;  4O1P A;  3FBV A;  2A2D A;  3I9V 1;  4GXT A;  4PL5 A;  3VA9 A;  2V6E A;  2L1L B;  4OAV B;  2P22 B;  4YZC A;  4G75 A;  4HFV A;  3DA4 A;  3LJ1 A;  4PL3 A;  3IAM 1;  4NV5 A;  3Q8D A;  3DO9 A;  4YZD A;  1U5K A;  1SJ8 A;  2V1C C;  3IAS 1;  3LJ0 A;  3DA3 A;  2FUG 1;  4Z7H A;  2F6M B;  2CAZ B;  4OAU C;  2RIO A;  3F4M A;  2XMX A;  3LJ2 A;  2XTQ A;  4U6R A;  4Q9V A;  2ZRR A;  4AS3 A;  4DWL A;  4NV2 A;  4YZ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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