2L1LB

Nmr solution structure of the phi0 pki nes peptide in complex with crm1-rangtp
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
127
structure length
127
Chain Sequence
ISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
pubmed doi rcsb
molecule keywords cAMP-dependent protein kinase inhibitor alpha
molecule tags Nuclear protein
source organism Homo sapiens
total genus 39
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2010-07-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.250 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 2l1lB00
2L1LB
chains in the Genus database with same CATH superfamily
4G75A 4OAVB 3VA9A 4AS3A 2V1CC 3FVVA 2A2DA 2GSCA 5HGIA 2QGMA 4G76A 2K19A 4YZDA 2F6MB 3UITA 1W3SA 2RIOA 2RLDA 3FBVA 3DO9A 2QZGA 1TDPA 4YZCA 3LJ0A 2FUG1 1JQOA 4AS2A 3L0IA 4O1OA 2XTRA 3DA4A 4YZ9A 4PL5A 2F66B 2YFAA 4NV2A 4PL4A 4Z7HA 2E8GA 1SJ8A 2CAZB 4PL3A 2FEFA 2JAEA 2XTQA 2HGKA 1U5KA 2JB3A 4GXTA 2ZW3A 3KP9A 3LJ2A 2YFBA 2XMXA 3DA3A 3LJ1A 2ZRRA 4DWLA 4I1TA 3B55A 3I9V1 4HEA1 2BL7A 3IAM1 4JCVE 2JB2A 3F4MA 2FU2A 4NV5A 3IAS1 4Z7GA 5LNK1 2MJFB 3FNBA 4Q9VA 2KKMA 2RADA 2JBWA 4U6RA 2QSBA 2V6EA 2IP6A 2L1LB 2A2CA 4HFVA 3P23A 2ETDA 2P22B 3JSBA 3AJFA 4OAUC 2JB1A 2BL8A 4O1PA 3SDJA 3Q8DA 1YO7A
chains in the Genus database with same CATH topology
4G75A 4OAVB 3VA9A 4AS3A 2V1CC 2A2DA 5HGIA 4G76A 2K19A 4YZDA 2F6MB 3UITA 1W3SA 2RIOA 3FBVA 3DO9A 4YZCA 3LJ0A 2FUG1 4AS2A 3L0IA 4O1OA 2XTRA 3DA4A 4YZ9A 4PL5A 2F66B 2YFAA 4NV2A 4PL4A 4Z7HA 2E8GA 1SJ8A 2CAZB 4PL3A 2JAEA 2XTQA 1U5KA 2JB3A 4GXTA 3KP9A 3LJ2A 2YFBA 2XMXA 3DA3A 3LJ1A 2ZRRA 4DWLA 4I1TA 3I9V1 4HEA1 3IAM1 4JCVE 2JB2A 3F4MA 4NV5A 3IAS1 4Z7GA 5LNK1 2MJFB 4Q9VA 2KKMA 4U6RA 2V6EA 2IP6A 2L1LB 2A2CA 4HFVA 3P23A 2P22B 3JSBA 3AJFA 4OAUC 2JB1A 4O1PA 3SDJA 3Q8DA 1YO7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L1L B; 
#chains in the Genus database with same CATH topology
 4G75 A;  4OAV B;  3VA9 A;  4AS3 A;  2V1C C;  3FVV A;  2A2D A;  2GSC A;  5HGI A;  2QGM A;  4G76 A;  2K19 A;  4YZD A;  2F6M B;  3UIT A;  1W3S A;  2RIO A;  2RLD A;  3FBV A;  3DO9 A;  2QZG A;  1TDP A;  4YZC A;  3LJ0 A;  2FUG 1;  1JQO A;  4AS2 A;  3L0I A;  4O1O A;  2XTR A;  3DA4 A;  4YZ9 A;  4PL5 A;  2F66 B;  2YFA A;  4NV2 A;  4PL4 A;  4Z7H A;  2E8G A;  1SJ8 A;  2CAZ B;  4PL3 A;  2FEF A;  2JAE A;  2XTQ A;  2HGK A;  1U5K A;  2JB3 A;  4GXT A;  2ZW3 A;  3KP9 A;  3LJ2 A;  2YFB A;  2XMX A;  3DA3 A;  3LJ1 A;  2ZRR A;  4DWL A;  4I1T A;  3B55 A;  3I9V 1;  4HEA 1;  2BL7 A;  3IAM 1;  4JCV E;  2JB2 A;  3F4M A;  2FU2 A;  4NV5 A;  3IAS 1;  4Z7G A;  5LNK 1;  2MJF B;  3FNB A;  4Q9V A;  2KKM A;  2RAD A;  2JBW A;  4U6R A;  2QSB A;  2V6E A;  2IP6 A;  2L1L B;  2A2C A;  4HFV A;  3P23 A;  2ETD A;  2P22 B;  3JSB A;  3AJF A;  4OAU C;  2JB1 A;  2BL8 A;  4O1P A;  3SDJ A;  3Q8D A;  1YO7 A; 
#chains in the Genus database with same CATH homology
 4G75 A;  4OAV B;  3VA9 A;  4AS3 A;  2V1C C;  2A2D A;  5HGI A;  4G76 A;  2K19 A;  4YZD A;  2F6M B;  3UIT A;  1W3S A;  2RIO A;  3FBV A;  3DO9 A;  4YZC A;  3LJ0 A;  2FUG 1;  4AS2 A;  3L0I A;  4O1O A;  2XTR A;  3DA4 A;  4YZ9 A;  4PL5 A;  2F66 B;  2YFA A;  4NV2 A;  4PL4 A;  4Z7H A;  2E8G A;  1SJ8 A;  2CAZ B;  4PL3 A;  2JAE A;  2XTQ A;  1U5K A;  2JB3 A;  4GXT A;  3KP9 A;  3LJ2 A;  2YFB A;  2XMX A;  3DA3 A;  3LJ1 A;  2ZRR A;  4DWL A;  4I1T A;  3I9V 1;  4HEA 1;  3IAM 1;  4JCV E;  2JB2 A;  3F4M A;  4NV5 A;  3IAS 1;  4Z7G A;  5LNK 1;  2MJF B;  4Q9V A;  2KKM A;  4U6R A;  2V6E A;  2IP6 A;  2L1L B;  2A2C A;  4HFV A;  3P23 A;  2P22 B;  3JSB A;  3AJF A;  4OAU C;  2JB1 A;  4O1P A;  3SDJ A;  3Q8D A;  1YO7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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