2ZW3A

Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
216
structure length
201
Chain Sequence
DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the connexin 26 gap junction channel at 3.5 A resolution
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Gap junction beta-2 protein
total genus 59
structure length 201
sequence length 216
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00029 Connexin Connexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.80 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) Gap junction channel protein cysteine-rich domain 2zw3A00
2ZW3A
chains in the Genus database with same CATH superfamily
2BL8A 2QZGA 3IAS1 2P22B 2YFBA 1YO7A 1TDPA 2V6EA 4I1TA 2JB1A 4Z7GA 4OAUC 2RADA 4Q9VA 2QSBA 4Z7HA 2BL7A 4G75A 3B55A 3LJ1A 4YZ9A 4HFVA 4DWLA 2JBWA 5LNK1 2KKMA 3LJ0A 4PL3A 2V1CC 2ETDA 2A2DA 3DA3A 3F4MA 2GSCA 1JQOA 2QGMA 2RLDA 4YZDA 3P23A 3FVVA 2JB3A 3DA4A 5HGIA 2XMXA 4O1PA 1U5KA 2L1LB 4GXTA 2JAEA 3KP9A 2FEFA 2ZW3A 3Q8DA 2FUG1 2FU2A 2RIOA 3LJ2A 2ZRRA 4PL4A 4YZCA 2JB2A 2MJFB 2K19A 2XTQA 3L0IA 4NV5A 3SDJA 3DO9A 2F66B 2IP6A 1W3SA 2CAZB 3AJFA 2F6MB 4G76A 3FBVA 4U6RA 3JSBA 2HGKA 2E8GA 2A2CA 4O1OA 3IAM1 3FNBA 4OAVB 2XTRA 4JCVE 3VA9A 4NV2A 4AS3A 1SJ8A 3UITA 4AS2A 2YFAA 3I9V1 4HEA1 4PL5A
chains in the Genus database with same CATH topology
2ZW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZW3 A; 
#chains in the Genus database with same CATH topology
 2BL8 A;  2QZG A;  3IAS 1;  2P22 B;  2YFB A;  1YO7 A;  1TDP A;  2V6E A;  4I1T A;  2JB1 A;  4Z7G A;  4OAU C;  2RAD A;  4Q9V A;  2QSB A;  4Z7H A;  2BL7 A;  4G75 A;  3B55 A;  3LJ1 A;  4YZ9 A;  4HFV A;  4DWL A;  2JBW A;  5LNK 1;  2KKM A;  3LJ0 A;  4PL3 A;  2V1C C;  2ETD A;  2A2D A;  3DA3 A;  3F4M A;  2GSC A;  1JQO A;  2QGM A;  2RLD A;  4YZD A;  3P23 A;  3FVV A;  2JB3 A;  3DA4 A;  5HGI A;  2XMX A;  4O1P A;  1U5K A;  2L1L B;  4GXT A;  2JAE A;  3KP9 A;  2FEF A;  2ZW3 A;  3Q8D A;  2FUG 1;  2FU2 A;  2RIO A;  3LJ2 A;  2ZRR A;  4PL4 A;  4YZC A;  2JB2 A;  2MJF B;  2K19 A;  2XTQ A;  3L0I A;  4NV5 A;  3SDJ A;  3DO9 A;  2F66 B;  2IP6 A;  1W3S A;  2CAZ B;  3AJF A;  2F6M B;  4G76 A;  3FBV A;  4U6R A;  3JSB A;  2HGK A;  2E8G A;  2A2C A;  4O1O A;  3IAM 1;  3FNB A;  4OAV B;  2XTR A;  4JCV E;  3VA9 A;  4NV2 A;  4AS3 A;  1SJ8 A;  3UIT A;  4AS2 A;  2YFA A;  3I9V 1;  4HEA 1;  4PL5 A; 
#chains in the Genus database with same CATH homology
 2ZW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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