2ZW3A

Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
216
structure length
201
Chain Sequence
DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the connexin 26 gap junction channel at 3.5 A resolution
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Gap junction beta-2 protein
total genus 59
structure length 201
sequence length 216
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00029 Connexin Connexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.80 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) Gap junction channel protein cysteine-rich domain 2zw3A00
2ZW3A
chains in the Genus database with same CATH superfamily
2RIOA 2JB2A 1SJ8A 3Q8DA 2JB1A 2GSCA 2E8GA 2ZRRA 2ZW3A 3P23A 2IP6A 2YFBA 3JSBA 2CAZB 2V6EA 3FVVA 4OAUC 4U6RA 4NV5A 4NV2A 4AS3A 4OAVB 3AJFA 2K19A 4YZDA 2FEFA 2XTQA 3UITA 2ETDA 2FUG1 2XTRA 2F6MB 4GXTA 3IAS1 3DA4A 4HFVA 2A2CA 3B55A 4PL4A 2QSBA 3SDJA 1TDPA 2KKMA 3DO9A 3L0IA 2BL8A 4O1OA 2XMXA 4PL3A 4YZ9A 4Q9VA 2L1LB 4AS2A 2YFAA 1U5KA 4PL5A 4G76A 2HGKA 3LJ2A 4Z7GA 4Z7HA 3DA3A 2MJFB 3LJ0A 4G75A 2QZGA 2JAEA 5HGIA 3F4MA 2JB3A 4DWLA 4O1PA 2A2DA 1YO7A 3KP9A 3VA9A 5LNK1 2JBWA 4HEA1 3IAM1 2RADA 3I9V1 2BL7A 2FU2A 3FBVA 3FNBA 2P22B 2F66B 4I1TA 2V1CC 2RLDA 2QGMA 4JCVE 1W3SA 4YZCA 1JQOA 3LJ1A
chains in the Genus database with same CATH topology
2ZW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZW3 A; 
#chains in the Genus database with same CATH topology
 2RIO A;  2JB2 A;  1SJ8 A;  3Q8D A;  2JB1 A;  2GSC A;  2E8G A;  2ZRR A;  2ZW3 A;  3P23 A;  2IP6 A;  2YFB A;  3JSB A;  2CAZ B;  2V6E A;  3FVV A;  4OAU C;  4U6R A;  4NV5 A;  4NV2 A;  4AS3 A;  4OAV B;  3AJF A;  2K19 A;  4YZD A;  2FEF A;  2XTQ A;  3UIT A;  2ETD A;  2FUG 1;  2XTR A;  2F6M B;  4GXT A;  3IAS 1;  3DA4 A;  4HFV A;  2A2C A;  3B55 A;  4PL4 A;  2QSB A;  3SDJ A;  1TDP A;  2KKM A;  3DO9 A;  3L0I A;  2BL8 A;  4O1O A;  2XMX A;  4PL3 A;  4YZ9 A;  4Q9V A;  2L1L B;  4AS2 A;  2YFA A;  1U5K A;  4PL5 A;  4G76 A;  2HGK A;  3LJ2 A;  4Z7G A;  4Z7H A;  3DA3 A;  2MJF B;  3LJ0 A;  4G75 A;  2QZG A;  2JAE A;  5HGI A;  3F4M A;  2JB3 A;  4DWL A;  4O1P A;  2A2D A;  1YO7 A;  3KP9 A;  3VA9 A;  5LNK 1;  2JBW A;  4HEA 1;  3IAM 1;  2RAD A;  3I9V 1;  2BL7 A;  2FU2 A;  3FBV A;  3FNB A;  2P22 B;  2F66 B;  4I1T A;  2V1C C;  2RLD A;  2QGM A;  4JCV E;  1W3S A;  4YZC A;  1JQO A;  3LJ1 A; 
#chains in the Genus database with same CATH homology
 2ZW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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