3F4MA

Crystal structure of tipe2
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
154
structure length
154
Chain Sequence
IDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TIPE2 provides insights into immune homeostasis
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Tumor necrosis factor, alpha-induced protein 8-like protein
total genus 66
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-11-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.160 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 3f4mA00
4Q9VA 3F4MA
chains in the Genus database with same CATH superfamily
3B55A 4O1OA 3SDJA 1JQOA 2FU2A 2L1LB 2V6EA 4YZ9A 2IP6A 1W3SA 3FNBA 2BL8A 2E8GA 4AS2A 3LJ1A 2YFBA 3Q8DA 2QZGA 2BL7A 3VA9A 4HEA1 4YZCA 2YFAA 2V1CC 2XTRA 3UITA 4OAUC 4Z7GA 2F6MB 2K19A 2FEFA 2F66B 4I1TA 2ZW3A 5LNK1 2QSBA 2JB1A 2ZRRA 4PL4A 3IAM1 1YO7A 3FVVA 4G76A 2FUG1 2RADA 2A2CA 2RIOA 4U6RA 3L0IA 4NV2A 4PL3A 4AS3A 2XTQA 2HGKA 3KP9A 4NV5A 4JCVE 4G75A 4YZDA 5HGIA 2KKMA 3DA3A 2MJFB 3DO9A 4PL5A 2CAZB 2P22B 3DA4A 4Q9VA 2JB2A 4O1PA 3JSBA 4Z7HA 1TDPA 2JAEA 3IAS1 3LJ0A 3AJFA 3LJ2A 3I9V1 4DWLA 3FBVA 2QGMA 2A2DA 2GSCA 4HFVA 2JBWA 3F4MA 4GXTA 2RLDA 1U5KA 2JB3A 3P23A 1SJ8A 4OAVB 2ETDA 2XMXA
chains in the Genus database with same CATH topology
4O1OA 3SDJA 2L1LB 2V6EA 4YZ9A 2IP6A 1W3SA 2E8GA 4AS2A 3LJ1A 2YFBA 3Q8DA 3VA9A 4HEA1 4YZCA 2YFAA 2V1CC 2XTRA 3UITA 4OAUC 4Z7GA 2F6MB 2K19A 2F66B 4I1TA 5LNK1 2ZRRA 2JB1A 4PL4A 3IAM1 1YO7A 2FUG1 4G76A 2A2CA 2RIOA 4U6RA 3L0IA 4NV2A 4PL3A 4AS3A 2XTQA 3KP9A 4NV5A 4JCVE 4G75A 4YZDA 5HGIA 2KKMA 3DA3A 2MJFB 3DO9A 4PL5A 2CAZB 2P22B 3DA4A 4Q9VA 2JB2A 4O1PA 3JSBA 4Z7HA 2JAEA 3IAS1 3LJ0A 3AJFA 3LJ2A 3I9V1 4DWLA 3FBVA 2A2DA 4HFVA 3F4MA 4GXTA 1U5KA 2JB3A 3P23A 1SJ8A 4OAVB 2XMXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q9V A;  3F4M A; 
#chains in the Genus database with same CATH topology
 3B55 A;  4O1O A;  3SDJ A;  1JQO A;  2FU2 A;  2L1L B;  2V6E A;  4YZ9 A;  2IP6 A;  1W3S A;  3FNB A;  2BL8 A;  2E8G A;  4AS2 A;  3LJ1 A;  2YFB A;  3Q8D A;  2QZG A;  2BL7 A;  3VA9 A;  4HEA 1;  4YZC A;  2YFA A;  2V1C C;  2XTR A;  3UIT A;  4OAU C;  4Z7G A;  2F6M B;  2K19 A;  2FEF A;  2F66 B;  4I1T A;  2ZW3 A;  5LNK 1;  2QSB A;  2JB1 A;  2ZRR A;  4PL4 A;  3IAM 1;  1YO7 A;  3FVV A;  4G76 A;  2FUG 1;  2RAD A;  2A2C A;  2RIO A;  4U6R A;  3L0I A;  4NV2 A;  4PL3 A;  4AS3 A;  2XTQ A;  2HGK A;  3KP9 A;  4NV5 A;  4JCV E;  4G75 A;  4YZD A;  5HGI A;  2KKM A;  3DA3 A;  2MJF B;  3DO9 A;  4PL5 A;  2CAZ B;  2P22 B;  3DA4 A;  4Q9V A;  2JB2 A;  4O1P A;  3JSB A;  4Z7H A;  1TDP A;  2JAE A;  3IAS 1;  3LJ0 A;  3AJF A;  3LJ2 A;  3I9V 1;  4DWL A;  3FBV A;  2QGM A;  2A2D A;  2GSC A;  4HFV A;  2JBW A;  3F4M A;  4GXT A;  2RLD A;  1U5K A;  2JB3 A;  3P23 A;  1SJ8 A;  4OAV B;  2ETD A;  2XMX A; 
#chains in the Genus database with same CATH homology
 4O1O A;  3SDJ A;  2L1L B;  2V6E A;  4YZ9 A;  2IP6 A;  1W3S A;  2E8G A;  4AS2 A;  3LJ1 A;  2YFB A;  3Q8D A;  3VA9 A;  4HEA 1;  4YZC A;  2YFA A;  2V1C C;  2XTR A;  3UIT A;  4OAU C;  4Z7G A;  2F6M B;  2K19 A;  2F66 B;  4I1T A;  5LNK 1;  2ZRR A;  2JB1 A;  4PL4 A;  3IAM 1;  1YO7 A;  2FUG 1;  4G76 A;  2A2C A;  2RIO A;  4U6R A;  3L0I A;  4NV2 A;  4PL3 A;  4AS3 A;  2XTQ A;  3KP9 A;  4NV5 A;  4JCV E;  4G75 A;  4YZD A;  5HGI A;  2KKM A;  3DA3 A;  2MJF B;  3DO9 A;  4PL5 A;  2CAZ B;  2P22 B;  3DA4 A;  4Q9V A;  2JB2 A;  4O1P A;  3JSB A;  4Z7H A;  2JAE A;  3IAS 1;  3LJ0 A;  3AJF A;  3LJ2 A;  3I9V 1;  4DWL A;  3FBV A;  2A2D A;  4HFV A;  3F4M A;  4GXT A;  1U5K A;  2JB3 A;  3P23 A;  1SJ8 A;  4OAV B;  2XMX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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