3F4MA

Crystal structure of tipe2
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
154
structure length
154
Chain Sequence
IDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TIPE2 provides insights into immune homeostasis
pubmed doi rcsb
molecule keywords Tumor necrosis factor, alpha-induced protein 8-like protein
molecule tags Immune system
source organism Homo sapiens
total genus 66
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-11-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.160 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 3f4mA00
3F4MA 4Q9VA
chains in the Genus database with same CATH superfamily
1TDPA 3FNBA 5LNK1 2XMXA 4AS3A 4YZ9A 2BL8A 2JB3A 3FVVA 2QZGA 4U6RA 1JQOA 4DWLA 4G75A 2FU2A 3KP9A 2HGKA 2P22B 4HEA1 2FUG1 4JCVE 4OAVB 4PL4A 4Q9VA 3AJFA 2GSCA 4I1TA 1U5KA 3Q8DA 3P23A 4G76A 3IAS1 2RIOA 2A2DA 2XTRA 4HFVA 2A2CA 3LJ1A 4YZCA 2RADA 4AS2A 2V6EA 3LJ2A 3LJ0A 4O1OA 3DA4A 4PL5A 4PL3A 2JAEA 1SJ8A 2F66B 2CAZB 5HGIA 2F6MB 2K19A 3IAM1 3SDJA 3B55A 4NV2A 4Z7HA 4OAUC 2XTQA 4GXTA 2JB2A 3DA3A 2QGMA 3L0IA 3DO9A 4O1PA 2IP6A 4NV5A 2JBWA 2MJFB 2V1CC 1W3SA 3F4MA 2YFBA 3I9V1 4YZDA 3FBVA 2YFAA 2E8GA 2FEFA 2ZRRA 2L1LB 3VA9A 2BL7A 1YO7A 3UITA 2KKMA 3JSBA 2ZW3A 2ETDA 2JB1A 4Z7GA 2QSBA 2RLDA
chains in the Genus database with same CATH topology
5LNK1 2XMXA 4AS3A 4YZ9A 2JB3A 4U6RA 4DWLA 4G75A 3KP9A 2P22B 4HEA1 2FUG1 4JCVE 4OAVB 4PL4A 4Q9VA 3AJFA 4I1TA 1U5KA 3Q8DA 3P23A 4G76A 3IAS1 2RIOA 2A2DA 2XTRA 4HFVA 2A2CA 3LJ1A 4YZCA 4AS2A 2V6EA 3LJ2A 3LJ0A 4O1OA 3DA4A 4PL5A 4PL3A 2JAEA 1SJ8A 2F66B 2CAZB 5HGIA 2F6MB 2K19A 3IAM1 3SDJA 4NV2A 4Z7HA 4OAUC 2XTQA 4GXTA 2JB2A 3DA3A 3L0IA 3DO9A 4O1PA 2IP6A 4NV5A 2MJFB 2V1CC 1W3SA 3F4MA 2YFBA 3I9V1 4YZDA 3FBVA 2YFAA 2E8GA 2ZRRA 2L1LB 3VA9A 1YO7A 3UITA 2KKMA 3JSBA 2JB1A 4Z7GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F4M A;  4Q9V A; 
#chains in the Genus database with same CATH topology
 1TDP A;  3FNB A;  5LNK 1;  2XMX A;  4AS3 A;  4YZ9 A;  2BL8 A;  2JB3 A;  3FVV A;  2QZG A;  4U6R A;  1JQO A;  4DWL A;  4G75 A;  2FU2 A;  3KP9 A;  2HGK A;  2P22 B;  4HEA 1;  2FUG 1;  4JCV E;  4OAV B;  4PL4 A;  4Q9V A;  3AJF A;  2GSC A;  4I1T A;  1U5K A;  3Q8D A;  3P23 A;  4G76 A;  3IAS 1;  2RIO A;  2A2D A;  2XTR A;  4HFV A;  2A2C A;  3LJ1 A;  4YZC A;  2RAD A;  4AS2 A;  2V6E A;  3LJ2 A;  3LJ0 A;  4O1O A;  3DA4 A;  4PL5 A;  4PL3 A;  2JAE A;  1SJ8 A;  2F66 B;  2CAZ B;  5HGI A;  2F6M B;  2K19 A;  3IAM 1;  3SDJ A;  3B55 A;  4NV2 A;  4Z7H A;  4OAU C;  2XTQ A;  4GXT A;  2JB2 A;  3DA3 A;  2QGM A;  3L0I A;  3DO9 A;  4O1P A;  2IP6 A;  4NV5 A;  2JBW A;  2MJF B;  2V1C C;  1W3S A;  3F4M A;  2YFB A;  3I9V 1;  4YZD A;  3FBV A;  2YFA A;  2E8G A;  2FEF A;  2ZRR A;  2L1L B;  3VA9 A;  2BL7 A;  1YO7 A;  3UIT A;  2KKM A;  3JSB A;  2ZW3 A;  2ETD A;  2JB1 A;  4Z7G A;  2QSB A;  2RLD A; 
#chains in the Genus database with same CATH homology
 5LNK 1;  2XMX A;  4AS3 A;  4YZ9 A;  2JB3 A;  4U6R A;  4DWL A;  4G75 A;  3KP9 A;  2P22 B;  4HEA 1;  2FUG 1;  4JCV E;  4OAV B;  4PL4 A;  4Q9V A;  3AJF A;  4I1T A;  1U5K A;  3Q8D A;  3P23 A;  4G76 A;  3IAS 1;  2RIO A;  2A2D A;  2XTR A;  4HFV A;  2A2C A;  3LJ1 A;  4YZC A;  4AS2 A;  2V6E A;  3LJ2 A;  3LJ0 A;  4O1O A;  3DA4 A;  4PL5 A;  4PL3 A;  2JAE A;  1SJ8 A;  2F66 B;  2CAZ B;  5HGI A;  2F6M B;  2K19 A;  3IAM 1;  3SDJ A;  4NV2 A;  4Z7H A;  4OAU C;  2XTQ A;  4GXT A;  2JB2 A;  3DA3 A;  3L0I A;  3DO9 A;  4O1P A;  2IP6 A;  4NV5 A;  2MJF B;  2V1C C;  1W3S A;  3F4M A;  2YFB A;  3I9V 1;  4YZD A;  3FBV A;  2YFA A;  2E8G A;  2ZRR A;  2L1L B;  3VA9 A;  1YO7 A;  3UIT A;  2KKM A;  3JSB A;  2JB1 A;  4Z7G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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