3F4MA

Crystal structure of tipe2
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
154
structure length
154
Chain Sequence
IDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TIPE2 provides insights into immune homeostasis
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Tumor necrosis factor, alpha-induced protein 8-like protein
total genus 66
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2008-11-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.160 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 3f4mA00
3F4MA 4Q9VA
chains in the Genus database with same CATH superfamily
4NV2A 1SJ8A 1JQOA 3I9V1 1TDPA 4AS3A 3LJ2A 2K19A 2RLDA 2V1CC 4G76A 2JAEA 2E8GA 5HGIA 4Q9VA 4NV5A 4YZ9A 4OAUC 3SDJA 3KP9A 4YZDA 2HGKA 3LJ1A 3FNBA 2KKMA 4Z7GA 2QGMA 2F6MB 3B55A 3IAM1 4O1OA 4OAVB 3VA9A 4DWLA 4PL5A 3DO9A 2FEFA 4HEA1 3Q8DA 2CAZB 2FU2A 2XTQA 2XTRA 2XMXA 2ZRRA 2L1LB 3LJ0A 1U5KA 2A2CA 2JB2A 2P22B 2MJFB 2RIOA 2YFAA 4U6RA 4GXTA 2ZW3A 3DA3A 3F4MA 3FBVA 3IAS1 1W3SA 2ETDA 2QSBA 3UITA 4YZCA 4AS2A 2YFBA 2JBWA 2QZGA 3JSBA 3DA4A 2GSCA 4G75A 2JB1A 2RADA 4I1TA 2BL8A 4PL3A 4O1PA 2V6EA 1YO7A 2IP6A 5LNK1 3FVVA 2JB3A 4JCVE 4PL4A 3AJFA 2BL7A 2A2DA 2F66B 3P23A 4HFVA 2FUG1 3L0IA 4Z7HA
chains in the Genus database with same CATH topology
4NV2A 1SJ8A 3I9V1 4AS3A 3LJ2A 2K19A 2V1CC 4G76A 2JAEA 2E8GA 5HGIA 4Q9VA 4NV5A 4YZ9A 4OAUC 3SDJA 3KP9A 4YZDA 3LJ1A 2KKMA 4Z7GA 2F6MB 3IAM1 4O1OA 4OAVB 3VA9A 4DWLA 4PL5A 3DO9A 4HEA1 3Q8DA 2CAZB 2XTQA 2XTRA 2XMXA 2ZRRA 2L1LB 3LJ0A 1U5KA 2A2CA 2JB2A 2P22B 2MJFB 2RIOA 2YFAA 4U6RA 4GXTA 3DA3A 3F4MA 3FBVA 3IAS1 1W3SA 3UITA 4YZCA 4AS2A 2YFBA 3JSBA 3DA4A 4G75A 2JB1A 4I1TA 4PL3A 4O1PA 2V6EA 1YO7A 2IP6A 5LNK1 2JB3A 4JCVE 4PL4A 3AJFA 2A2DA 2F66B 3P23A 4HFVA 2FUG1 3L0IA 4Z7HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F4M A;  4Q9V A; 
#chains in the Genus database with same CATH topology
 4NV2 A;  1SJ8 A;  1JQO A;  3I9V 1;  1TDP A;  4AS3 A;  3LJ2 A;  2K19 A;  2RLD A;  2V1C C;  4G76 A;  2JAE A;  2E8G A;  5HGI A;  4Q9V A;  4NV5 A;  4YZ9 A;  4OAU C;  3SDJ A;  3KP9 A;  4YZD A;  2HGK A;  3LJ1 A;  3FNB A;  2KKM A;  4Z7G A;  2QGM A;  2F6M B;  3B55 A;  3IAM 1;  4O1O A;  4OAV B;  3VA9 A;  4DWL A;  4PL5 A;  3DO9 A;  2FEF A;  4HEA 1;  3Q8D A;  2CAZ B;  2FU2 A;  2XTQ A;  2XTR A;  2XMX A;  2ZRR A;  2L1L B;  3LJ0 A;  1U5K A;  2A2C A;  2JB2 A;  2P22 B;  2MJF B;  2RIO A;  2YFA A;  4U6R A;  4GXT A;  2ZW3 A;  3DA3 A;  3F4M A;  3FBV A;  3IAS 1;  1W3S A;  2ETD A;  2QSB A;  3UIT A;  4YZC A;  4AS2 A;  2YFB A;  2JBW A;  2QZG A;  3JSB A;  3DA4 A;  2GSC A;  4G75 A;  2JB1 A;  2RAD A;  4I1T A;  2BL8 A;  4PL3 A;  4O1P A;  2V6E A;  1YO7 A;  2IP6 A;  5LNK 1;  3FVV A;  2JB3 A;  4JCV E;  4PL4 A;  3AJF A;  2BL7 A;  2A2D A;  2F66 B;  3P23 A;  4HFV A;  2FUG 1;  3L0I A;  4Z7H A; 
#chains in the Genus database with same CATH homology
 4NV2 A;  1SJ8 A;  3I9V 1;  4AS3 A;  3LJ2 A;  2K19 A;  2V1C C;  4G76 A;  2JAE A;  2E8G A;  5HGI A;  4Q9V A;  4NV5 A;  4YZ9 A;  4OAU C;  3SDJ A;  3KP9 A;  4YZD A;  3LJ1 A;  2KKM A;  4Z7G A;  2F6M B;  3IAM 1;  4O1O A;  4OAV B;  3VA9 A;  4DWL A;  4PL5 A;  3DO9 A;  4HEA 1;  3Q8D A;  2CAZ B;  2XTQ A;  2XTR A;  2XMX A;  2ZRR A;  2L1L B;  3LJ0 A;  1U5K A;  2A2C A;  2JB2 A;  2P22 B;  2MJF B;  2RIO A;  2YFA A;  4U6R A;  4GXT A;  3DA3 A;  3F4M A;  3FBV A;  3IAS 1;  1W3S A;  3UIT A;  4YZC A;  4AS2 A;  2YFB A;  3JSB A;  3DA4 A;  4G75 A;  2JB1 A;  4I1T A;  4PL3 A;  4O1P A;  2V6E A;  1YO7 A;  2IP6 A;  5LNK 1;  2JB3 A;  4JCV E;  4PL4 A;  3AJF A;  2A2D A;  2F66 B;  3P23 A;  4HFV A;  2FUG 1;  3L0I A;  4Z7H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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