3H3T | Genus

Total Genus 62

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	62
sequence length	236
structure length	236
Chain Sequence	GTHRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lipid transport
source organism	Homo sapiens
publication title	Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. pubmed doi rcsb
molecule keywords	Goodpasture antigen binding protein
total genus	62
structure length	236
sequence length	236
chains with identical sequence	B
ec nomenclature
pdb deposition date	2009-04-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01852	START	START domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.530.20	Alpha Beta	2-Layer Sandwich	Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4	Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4	3h3tA00

1VJHA 2EJXA 3KB0A 3NMTA 2E3QA 1KCMA 4C9CA 4DSBA 1ICXA 2FFSA 2KCZA 5JNNA 1T27A 2E3RA 2L9PA 4LGBA 3KAYA 3OTLA 1LLTA 2I9YA 3C0VA 3F08A 1EM2A 2LIOA 3P51A 3RT2A 4PSBA 4A80A 4BKCA 2VQ5A 4M9BA 2NS9A 2FLHA 3OQUA 3CNWA 4QIPA 3NMPA 4IGVA 4A84A 1UW5A 4FPWA 3TVRA 2E3OA 5E4DA 5E4BA 5AMWA 2Z9YA 4R7KA 1ZXFA 4MAPA 3KLXA 3H3TA 2LEQA 5BRLA 3Q63A 2RESA 3UIDA 2GKDA 3ELIA 2VNEA 1XDFA 3H3RA 2A1LA 3H3QA 4XRTA 1E09A 2REZA 2E3SA 2KF2A 5C9YA 2LUZA 1T17A 2E3PA 4XRWA 1IFVA 4BTZA 4A8UA 2M47A 1FM4A 2Q3QA 3NI8A 4JHGA 1LN1A 2M89A 3KDHA 4A8GA 3W9RA 3NMNA 3JRSA 4B9RA 3IE5A 1Z94A 3JRQB 4C94A 3OJIA 4M9WA 3RD6A 2E3MA 3NMHA 3W9KA 1QMRA 4MNSA 2MOUA 3K3KA 4A8VA 3TL1A 4A87A 5JO1A 5I9JA 3PU2A 2NN5A 4N0GC 2PSOA 3WG8A 3NEFA 4IH2A 4LG5A 4WVOA 4A85A 3NJ1A 2Z9ZA 3PUTA 4IGWA 2LCGA 1BTVA 3R6PA 4BK6A 2WQLA 3P9VA 4Z3LA 1FSKA 2LE1A 1XUVA 3NMVA 3IJTA 3KDJA 3TFZA 4OICA 4DS8A 4DSCA 4LGAA 1XN6A 4REJA 2LDKA 3KAZA 3TVQA 3H3SA 3NR4A 2QPVA 4BKDA 2KEWA 3NS2A 1X53A 2L8OA 2LF2A 3P0LA 4JHIA 4Q0KA 2KTEA 1JSSA 2LPXA 3Q6AA 2L65A 2LGHA 4Y31A 2PCSA 2QIMA 1XFSA 2E3NA 4JHHA 3FO5A 4N3EA 2K7HA 3KDIA 4A86A 5JO2A 2K5GA 4IH0A 2N4AA 2R55A 1XN5A 4A88A 2D4RA 3OH8A 1B6FA 4A81A 4RYVA 5E46A 3KB3A 3KL1A 3GGNA 4IGYA 1TXCA 4LA7A 4BK7A 4C9IA 3UJLA 2IL5A 3ZVUA 4REIA 1LN3A 1LN2A 3RT0C 2N4BA 4IGXA 4REHA 4A83A 2RERA 3K90A 4JDLA 3Q64A 4MA6A 5I8FA 3QN1A 2BK0A 1H2OA 3QSZA 3NEGA 3UQHA 4JDAA 3NJ0A 1TW0A 1BV1A 4GY9A 4IHRA 3NJOA 3E85A 5E4MA 2LAKA
chains in the Genus database with same CATH superfamily

1VJHA 2EJXA 3KB0A 3NMTA 2E3QA 1KCMA 4C9CA 4DSBA 1ICXA 2FFSA 3GTEA 2KCZA 5JNNA 1T27A 2E3RA 2L9PA 4LGBA 3KAYA 3OTLA 1LLTA 2I9YA 3C0VA 3F08A 1EM2A 4N76A 2LIOA 3P51A 3NQNA 4PSBA 3RT2A 4A80A 4BKCA 2VQ5A 3HO1A 4M9BA 2NS9A 2FLHA 3OQUA 3CNWA 4QIPA 3NMPA 4IGVA 4A84A 1UW5A 4FPWA 3TVRA 2E3OA 5E4DA 5E4BA 5AMWA 2Z9YA 3DLHA 4R7KA 1ZXFA 4QDCA 4MAPA 4E6FA 3KLXA 3H3TA 2LEQA 3GTSA 5BRLA 3Q63A 2RESA 3UIDA 2GKDA 2YH6A 2VNEA 3ELIA 1XDFA 2LAFA 3H3RA 2A1LA 3H3QA 4XRTA 1E09A 2REZA 5EKQC 2E3SA 2KF2A 5C9YA 2LUZA 1T17A 2E3PA 4XRWA 1IFVA 4BTZA 4KPYA 4A8UA 2M47A 1FM4A 2Q3QA 3F73A 3NI8A 4JHGA 1LN1A 4QDFB 2M89A 2ZYLA 3KDHA 4A8GA 3TGOC 3W9RA 3NMNA 3JRSA 4B9RA 3IE5A 1Z94A 3JRQB 4C94A 3OJIA 4M9WA 3GL2A 3RD6A 2E3MA 3NMHA 3W9KA 1QMRA 4MNSA 2MOUA 3K3KA 4A8VA 3TL1A 4A87A 4QDFA 5JO1A 5I9JA 3PU2A 2NN5A 4N0GC 2PSOA 3WG8A 3NEFA 4NCAA 4IH2A 4LG5A 4WVOA 4A85A 3NJ1A 2Z9ZA 3PUTA 4IGWA 2LCGA 1BTVA 3R6PA 4QCKA 2WQLA 3P9VA 4BK6A 1FSKA 2LE1A 1XUVA 4Z3LA 3NMVA 3IJTA 3KDJA 3TFZA 4OICA 4DS8A 4DSCA 4LGAA 1XN6A 4REJA 2LDKA 3GB4A 3KAZA 3H3SA 3NR4A 3TVQA 2QPVA 4BKDA 2KEWA 3NS2A 1X53A 2L8OA 2LF2A 3P0LA 4JHIA 3DLBA 4Q0KA 2KTEA 1JSSA 2LPXA 3Q6AA 3HVRA 3HK2A 2L65A 2LGHA 3GKEA 4Y31A 2PCSA 2QIMA 4N47A 1XFSA 2E3NA 4JHHA 3FO5A 4N3EA 2K7HA 3KDIA 4A86A 5JO2A 2K5GA 4IH0A 2N4AA 2R55A 1XN5A 4A88A 2D4RA 3OH8A 1B6FA 4A81A 4RYVA 5E46A 3KB3A 3KL1A 3GGNA 4IGYA 1TXCA 4LA7A 4BK7A 4C9IA 3UJLA 2IL5A 3ZVUA 4REIA 3HJFA 3HM9A 1LN3A 1LN2A 3RT0C 2N4BA 4IGXA 4JHYA 4N41A 4REHA 4A83A 2RERA 3K90A 4JDLA 3Q64A 4MA6A 5I8FA 3QN1A 2BK0A 4NCBA 1H2OA 3HXMA 3QSZA 3NEGA 3GOBA 3GL0A 3UQHA 4JDAA 3NJ0A 4QDDA 1TW0A 1BV1A 4GY9A 4IHRA 3NJOA 3E85A 5E4MA 2LAKA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1VJH A;  2EJX A;  3KB0 A;  3NMT A;  2E3Q A;  1KCM A;  4C9C A;  4DSB A;  1ICX A;  2FFS A;  2KCZ A;  5JNN A;  1T27 A;  2E3R A;  2L9P A;  4LGB A;  3KAY A;  3OTL A;  1LLT A;  2I9Y A;  3C0V A;  3F08 A;  1EM2 A;  2LIO A;  3P51 A;  3RT2 A;  4PSB A;  4A80 A;  4BKC A;  2VQ5 A;  4M9B A;  2NS9 A;  2FLH A;  3OQU A;  3CNW A;  4QIP A;  3NMP A;  4IGV A;  4A84 A;  1UW5 A;  4FPW A;  3TVR A;  2E3O A;  5E4D A;  5E4B A;  5AMW A;  2Z9Y A;  4R7K A;  1ZXF A;  4MAP A;  3KLX A;  3H3T A;  2LEQ A;  5BRL A;  3Q63 A;  2RES A;  3UID A;  2GKD A;  3ELI A;  2VNE A;  1XDF A;  3H3R A;  2A1L A;  3H3Q A;  4XRT A;  1E09 A;  2REZ A;  2E3S A;  2KF2 A;  5C9Y A;  2LUZ A;  1T17 A;  2E3P A;  4XRW A;  1IFV A;  4BTZ A;  4A8U A;  2M47 A;  1FM4 A;  2Q3Q A;  3NI8 A;  4JHG A;  1LN1 A;  2M89 A;  3KDH A;  4A8G A;  3W9R A;  3NMN A;  3JRS A;  4B9R A;  3IE5 A;  1Z94 A;  3JRQ B;  4C94 A;  3OJI A;  4M9W A;  3RD6 A;  2E3M A;  3NMH A;  3W9K A;  1QMR A;  4MNS A;  2MOU A;  3K3K A;  4A8V A;  3TL1 A;  4A87 A;  5JO1 A;  5I9J A;  3PU2 A;  2NN5 A;  4N0G C;  2PSO A;  3WG8 A;  3NEF A;  4IH2 A;  4LG5 A;  4WVO A;  4A85 A;  3NJ1 A;  2Z9Z A;  3PUT A;  4IGW A;  2LCG A;  1BTV A;  3R6P A;  4BK6 A;  2WQL A;  3P9V A;  4Z3L A;  1FSK A;  2LE1 A;  1XUV A;  3NMV A;  3IJT A;  3KDJ A;  3TFZ A;  4OIC A;  4DS8 A;  4DSC A;  4LGA A;  1XN6 A;  4REJ A;  2LDK A;  3KAZ A;  3TVQ A;  3H3S A;  3NR4 A;  2QPV A;  4BKD A;  2KEW A;  3NS2 A;  1X53 A;  2L8O A;  2LF2 A;  3P0L A;  4JHI A;  4Q0K A;  2KTE A;  1JSS A;  2LPX A;  3Q6A A;  2L65 A;  2LGH A;  4Y31 A;  2PCS A;  2QIM A;  1XFS A;  2E3N A;  4JHH A;  3FO5 A;  4N3E A;  2K7H A;  3KDI A;  4A86 A;  5JO2 A;  2K5G A;  4IH0 A;  2N4A A;  2R55 A;  1XN5 A;  4A88 A;  2D4R A;  3OH8 A;  1B6F A;  4A81 A;  4RYV A;  5E46 A;  3KB3 A;  3KL1 A;  3GGN A;  4IGY A;  1TXC A;  4LA7 A;  4BK7 A;  4C9I A;  3UJL A;  2IL5 A;  3ZVU A;  4REI A;  1LN3 A;  1LN2 A;  3RT0 C;  2N4B A;  4IGX A;  4REH A;  4A83 A;  2RER A;  3K90 A;  4JDL A;  3Q64 A;  4MA6 A;  5I8F A;  3QN1 A;  2BK0 A;  1H2O A;  3QSZ A;  3NEG A;  3UQH A;  4JDA A;  3NJ0 A;  1TW0 A;  1BV1 A;  4GY9 A;  4IHR A;  3NJO A;  3E85 A;  5E4M A;  2LAK A; 
#chains in the Genus database with same CATH topology
 1VJH A;  2EJX A;  3KB0 A;  3NMT A;  2E3Q A;  1KCM A;  4C9C A;  4DSB A;  1ICX A;  2FFS A;  3GTE A;  2KCZ A;  5JNN A;  1T27 A;  2E3R A;  2L9P A;  4LGB A;  3KAY A;  3OTL A;  1LLT A;  2I9Y A;  3C0V A;  3F08 A;  1EM2 A;  4N76 A;  2LIO A;  3P51 A;  3NQN A;  4PSB A;  3RT2 A;  4A80 A;  4BKC A;  2VQ5 A;  3HO1 A;  4M9B A;  2NS9 A;  2FLH A;  3OQU A;  3CNW A;  4QIP A;  3NMP A;  4IGV A;  4A84 A;  1UW5 A;  4FPW A;  3TVR A;  2E3O A;  5E4D A;  5E4B A;  5AMW A;  2Z9Y A;  3DLH A;  4R7K A;  1ZXF A;  4QDC A;  4MAP A;  4E6F A;  3KLX A;  3H3T A;  2LEQ A;  3GTS A;  5BRL A;  3Q63 A;  2RES A;  3UID A;  2GKD A;  2YH6 A;  2VNE A;  3ELI A;  1XDF A;  2LAF A;  3H3R A;  2A1L A;  3H3Q A;  4XRT A;  1E09 A;  2REZ A;  5EKQ C;  2E3S A;  2KF2 A;  5C9Y A;  2LUZ A;  1T17 A;  2E3P A;  4XRW A;  1IFV A;  4BTZ A;  4KPY A;  4A8U A;  2M47 A;  1FM4 A;  2Q3Q A;  3F73 A;  3NI8 A;  4JHG A;  1LN1 A;  4QDF B;  2M89 A;  2ZYL A;  3KDH A;  4A8G A;  3TGO C;  3W9R A;  3NMN A;  3JRS A;  4B9R A;  3IE5 A;  1Z94 A;  3JRQ B;  4C94 A;  3OJI A;  4M9W A;  3GL2 A;  3RD6 A;  2E3M A;  3NMH A;  3W9K A;  1QMR A;  4MNS A;  2MOU A;  3K3K A;  4A8V A;  3TL1 A;  4A87 A;  4QDF A;  5JO1 A;  5I9J A;  3PU2 A;  2NN5 A;  4N0G C;  2PSO A;  3WG8 A;  3NEF A;  4NCA A;  4IH2 A;  4LG5 A;  4WVO A;  4A85 A;  3NJ1 A;  2Z9Z A;  3PUT A;  4IGW A;  2LCG A;  1BTV A;  3R6P A;  4QCK A;  2WQL A;  3P9V A;  4BK6 A;  1FSK A;  2LE1 A;  1XUV A;  4Z3L A;  3NMV A;  3IJT A;  3KDJ A;  3TFZ A;  4OIC A;  4DS8 A;  4DSC A;  4LGA A;  1XN6 A;  4REJ A;  2LDK A;  3GB4 A;  3KAZ A;  3H3S A;  3NR4 A;  3TVQ A;  2QPV A;  4BKD A;  2KEW A;  3NS2 A;  1X53 A;  2L8O A;  2LF2 A;  3P0L A;  4JHI A;  3DLB A;  4Q0K A;  2KTE A;  1JSS A;  2LPX A;  3Q6A A;  3HVR A;  3HK2 A;  2L65 A;  2LGH A;  3GKE A;  4Y31 A;  2PCS A;  2QIM A;  4N47 A;  1XFS A;  2E3N A;  4JHH A;  3FO5 A;  4N3E A;  2K7H A;  3KDI A;  4A86 A;  5JO2 A;  2K5G A;  4IH0 A;  2N4A A;  2R55 A;  1XN5 A;  4A88 A;  2D4R A;  3OH8 A;  1B6F A;  4A81 A;  4RYV A;  5E46 A;  3KB3 A;  3KL1 A;  3GGN A;  4IGY A;  1TXC A;  4LA7 A;  4BK7 A;  4C9I A;  3UJL A;  2IL5 A;  3ZVU A;  4REI A;  3HJF A;  3HM9 A;  1LN3 A;  1LN2 A;  3RT0 C;  2N4B A;  4IGX A;  4JHY A;  4N41 A;  4REH A;  4A83 A;  2RER A;  3K90 A;  4JDL A;  3Q64 A;  4MA6 A;  5I8F A;  3QN1 A;  2BK0 A;  4NCB A;  1H2O A;  3HXM A;  3QSZ A;  3NEG A;  3GOB A;  3GL0 A;  3UQH A;  4JDA A;  3NJ0 A;  4QDD A;  1TW0 A;  1BV1 A;  4GY9 A;  4IHR A;  3NJO A;  3E85 A;  5E4M A;  2LAK A; 
#chains in the Genus database with same CATH homology
 1VJH A;  2EJX A;  3KB0 A;  3NMT A;  2E3Q A;  1KCM A;  4C9C A;  4DSB A;  1ICX A;  2FFS A;  3GTE A;  2KCZ A;  5JNN A;  1T27 A;  2E3R A;  2L9P A;  4LGB A;  3KAY A;  3OTL A;  1LLT A;  2I9Y A;  3C0V A;  3F08 A;  1EM2 A;  4N76 A;  2LIO A;  3P51 A;  3NQN A;  4PSB A;  3RT2 A;  4A80 A;  4BKC A;  2VQ5 A;  3HO1 A;  4M9B A;  2NS9 A;  2FLH A;  3OQU A;  3CNW A;  4QIP A;  3NMP A;  4IGV A;  4A84 A;  1UW5 A;  4FPW A;  3TVR A;  2E3O A;  5E4D A;  5E4B A;  5AMW A;  2Z9Y A;  3DLH A;  4R7K A;  1ZXF A;  4QDC A;  4MAP A;  4E6F A;  3KLX A;  3H3T A;  2LEQ A;  3GTS A;  5BRL A;  3Q63 A;  2RES A;  3UID A;  2GKD A;  2YH6 A;  2VNE A;  3ELI A;  1XDF A;  2LAF A;  3H3R A;  2A1L A;  3H3Q A;  4XRT A;  1E09 A;  2REZ A;  5EKQ C;  2E3S A;  2KF2 A;  5C9Y A;  2LUZ A;  1T17 A;  2E3P A;  4XRW A;  1IFV A;  4BTZ A;  4KPY A;  4A8U A;  2M47 A;  1FM4 A;  2Q3Q A;  3F73 A;  3NI8 A;  4JHG A;  1LN1 A;  4QDF B;  2M89 A;  2ZYL A;  3KDH A;  4A8G A;  3TGO C;  3W9R A;  3NMN A;  3JRS A;  4B9R A;  3IE5 A;  1Z94 A;  3JRQ B;  4C94 A;  3OJI A;  4M9W A;  3GL2 A;  3RD6 A;  2E3M A;  3NMH A;  3W9K A;  1QMR A;  4MNS A;  2MOU A;  3K3K A;  4A8V A;  3TL1 A;  4A87 A;  4QDF A;  5JO1 A;  5I9J A;  3PU2 A;  2NN5 A;  4N0G C;  2PSO A;  3WG8 A;  3NEF A;  4NCA A;  4IH2 A;  4LG5 A;  4WVO A;  4A85 A;  3NJ1 A;  2Z9Z A;  3PUT A;  4IGW A;  2LCG A;  1BTV A;  3R6P A;  4QCK A;  2WQL A;  3P9V A;  4BK6 A;  1FSK A;  2LE1 A;  1XUV A;  4Z3L A;  3NMV A;  3IJT A;  3KDJ A;  3TFZ A;  4OIC A;  4DS8 A;  4DSC A;  4LGA A;  1XN6 A;  4REJ A;  2LDK A;  3GB4 A;  3KAZ A;  3H3S A;  3NR4 A;  3TVQ A;  2QPV A;  4BKD A;  2KEW A;  3NS2 A;  1X53 A;  2L8O A;  2LF2 A;  3P0L A;  4JHI A;  3DLB A;  4Q0K A;  2KTE A;  1JSS A;  2LPX A;  3Q6A A;  3HVR A;  3HK2 A;  2L65 A;  2LGH A;  3GKE A;  4Y31 A;  2PCS A;  2QIM A;  4N47 A;  1XFS A;  2E3N A;  4JHH A;  3FO5 A;  4N3E A;  2K7H A;  3KDI A;  4A86 A;  5JO2 A;  2K5G A;  4IH0 A;  2N4A A;  2R55 A;  1XN5 A;  4A88 A;  2D4R A;  3OH8 A;  1B6F A;  4A81 A;  4RYV A;  5E46 A;  3KB3 A;  3KL1 A;  3GGN A;  4IGY A;  1TXC A;  4LA7 A;  4BK7 A;  4C9I A;  3UJL A;  2IL5 A;  3ZVU A;  4REI A;  3HJF A;  3HM9 A;  1LN3 A;  1LN2 A;  3RT0 C;  2N4B A;  4IGX A;  4JHY A;  4N41 A;  4REH A;  4A83 A;  2RER A;  3K90 A;  4JDL A;  3Q64 A;  4MA6 A;  5I8F A;  3QN1 A;  2BK0 A;  4NCB A;  1H2O A;  3HXM A;  3QSZ A;  3NEG A;  3GOB A;  3GL0 A;  3UQH A;  4JDA A;  3NJ0 A;  4QDD A;  1TW0 A;  1BV1 A;  4GY9 A;  4IHR A;  3NJO A;  3E85 A;  5E4M A;  2LAK A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

3H3TA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations