4Q9VA

Crystal structure of tipe3
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
183
structure length
183
Chain Sequence
FSSKSLALQAQKKILSKIASKTVANMLIDDTSSEIFDELYKVTKEHTHNKKEAHKIMKDLIKVAIKIGILYRNNQFSQEELVIVEKFRKKLNQTAMTIVSFYEVEYTFDRNVLSNLLHECKDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYSLDGDCRPNLKRICEGINKLLDEKVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Tumor necrosis factor alpha-induced protein 8-like protein 3
total genus 82
structure length 183
sequence length 183
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05527 DUF758 Domain of unknown function (DUF758)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.160 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 4q9vA00
3F4MA 4Q9VA
chains in the Genus database with same CATH superfamily
2A2DA 3IAM1 4Z7HA 2ETDA 4O1OA 2V1CC 3L0IA 1YO7A 4Q9VA 1W3SA 2QGMA 4I1TA 4JCVE 4Z7GA 3DA3A 4G76A 2IP6A 4O1PA 3UITA 4AS3A 4OAUC 5HGIA 2BL8A 2MJFB 3AJFA 2V6EA 2KKMA 3B55A 3VA9A 5LNK1 4NV2A 4PL4A 4HFVA 3FNBA 2RIOA 4PL3A 2BL7A 2JB2A 4NV5A 2XTQA 1JQOA 2QSBA 2JBWA 2FUG1 3DA4A 2ZRRA 4DWLA 3F4MA 4PL5A 3FVVA 2RADA 2CAZB 4YZCA 2YFBA 3FBVA 2A2CA 2L1LB 2JAEA 2ZW3A 3KP9A 4HEA1 4AS2A 2FU2A 4U6RA 2K19A 3LJ1A 4YZ9A 3LJ0A 2HGKA 3Q8DA 4G75A 4YZDA 4OAVB 3JSBA 2F66B 3LJ2A 2XTRA 1U5KA 2RLDA 2F6MB 3SDJA 2JB1A 2GSCA 2QZGA 2E8GA 3DO9A 2P22B 3P23A 3I9V1 3IAS1 4GXTA 1SJ8A 1TDPA 2FEFA 2YFAA 2XMXA 2JB3A
chains in the Genus database with same CATH topology
2A2DA 3IAM1 4Z7HA 2V1CC 3L0IA 4O1OA 1YO7A 4Q9VA 1W3SA 4I1TA 4JCVE 4Z7GA 3DA3A 4G76A 2IP6A 4O1PA 3UITA 4AS3A 4OAUC 5HGIA 2MJFB 3AJFA 2V6EA 2KKMA 3VA9A 5LNK1 4NV2A 4PL4A 4HFVA 2RIOA 4PL3A 2JB2A 4NV5A 2XTQA 2FUG1 3DA4A 2ZRRA 4DWLA 3F4MA 4PL5A 2CAZB 4YZCA 2YFBA 3FBVA 2A2CA 2L1LB 2JAEA 3KP9A 4HEA1 4AS2A 4U6RA 2K19A 3LJ1A 4YZ9A 3LJ0A 3Q8DA 4G75A 4YZDA 4OAVB 3JSBA 2F66B 3LJ2A 2XTRA 1U5KA 2F6MB 3SDJA 2JB1A 2E8GA 3DO9A 2P22B 3P23A 3I9V1 3IAS1 4GXTA 1SJ8A 2YFAA 2XMXA 2JB3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F4M A;  4Q9V A; 
#chains in the Genus database with same CATH topology
 2A2D A;  3IAM 1;  4Z7H A;  2ETD A;  4O1O A;  2V1C C;  3L0I A;  1YO7 A;  4Q9V A;  1W3S A;  2QGM A;  4I1T A;  4JCV E;  4Z7G A;  3DA3 A;  4G76 A;  2IP6 A;  4O1P A;  3UIT A;  4AS3 A;  4OAU C;  5HGI A;  2BL8 A;  2MJF B;  3AJF A;  2V6E A;  2KKM A;  3B55 A;  3VA9 A;  5LNK 1;  4NV2 A;  4PL4 A;  4HFV A;  3FNB A;  2RIO A;  4PL3 A;  2BL7 A;  2JB2 A;  4NV5 A;  2XTQ A;  1JQO A;  2QSB A;  2JBW A;  2FUG 1;  3DA4 A;  2ZRR A;  4DWL A;  3F4M A;  4PL5 A;  3FVV A;  2RAD A;  2CAZ B;  4YZC A;  2YFB A;  3FBV A;  2A2C A;  2L1L B;  2JAE A;  2ZW3 A;  3KP9 A;  4HEA 1;  4AS2 A;  2FU2 A;  4U6R A;  2K19 A;  3LJ1 A;  4YZ9 A;  3LJ0 A;  2HGK A;  3Q8D A;  4G75 A;  4YZD A;  4OAV B;  3JSB A;  2F66 B;  3LJ2 A;  2XTR A;  1U5K A;  2RLD A;  2F6M B;  3SDJ A;  2JB1 A;  2GSC A;  2QZG A;  2E8G A;  3DO9 A;  2P22 B;  3P23 A;  3I9V 1;  3IAS 1;  4GXT A;  1SJ8 A;  1TDP A;  2FEF A;  2YFA A;  2XMX A;  2JB3 A; 
#chains in the Genus database with same CATH homology
 2A2D A;  3IAM 1;  4Z7H A;  2V1C C;  3L0I A;  4O1O A;  1YO7 A;  4Q9V A;  1W3S A;  4I1T A;  4JCV E;  4Z7G A;  3DA3 A;  4G76 A;  2IP6 A;  4O1P A;  3UIT A;  4AS3 A;  4OAU C;  5HGI A;  2MJF B;  3AJF A;  2V6E A;  2KKM A;  3VA9 A;  5LNK 1;  4NV2 A;  4PL4 A;  4HFV A;  2RIO A;  4PL3 A;  2JB2 A;  4NV5 A;  2XTQ A;  2FUG 1;  3DA4 A;  2ZRR A;  4DWL A;  3F4M A;  4PL5 A;  2CAZ B;  4YZC A;  2YFB A;  3FBV A;  2A2C A;  2L1L B;  2JAE A;  3KP9 A;  4HEA 1;  4AS2 A;  4U6R A;  2K19 A;  3LJ1 A;  4YZ9 A;  3LJ0 A;  3Q8D A;  4G75 A;  4YZD A;  4OAV B;  3JSB A;  2F66 B;  3LJ2 A;  2XTR A;  1U5K A;  2F6M B;  3SDJ A;  2JB1 A;  2E8G A;  3DO9 A;  2P22 B;  3P23 A;  3I9V 1;  3IAS 1;  4GXT A;  1SJ8 A;  2YFA A;  2XMX A;  2JB3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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