3LF9A

Crystal structure of hiv epitope-scaffold 4e10_d0_1is1a_001_c
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
120
structure length
120
Chain Sequence
MINEIKKDAQERMDKSVEALKNNLSKVRTGGGGTEERRKDLVKIVRGEAEGGRVAVRNIARDAANDLAALGKDKEVNWFDISQALWEIQKLTDVAVKKIDEVLAAKEKELMEVLEHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
pubmed doi rcsb
molecule tags Immune system
source organism Artificial gene
molecule keywords 4E10_D0_1IS1A_001_C (T161)
total genus 51
structure length 120
sequence length 120
ec nomenclature
pdb deposition date 2010-01-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.20 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 3lf9A00
1WQGA 1DD5A 4L8IA 1EH1A 4GFQA 1WQHA 3LF9A 5JSNB 4JLRC 4OYDB 5JSBB 1ISEA 4KB2A 3LHPS 1EK8A 1GE9A 5MLC9 1WQFA 1Y698 4KC6A 4KB4A 4KDDA 1IS1A 4KAWX
chains in the Genus database with same CATH superfamily
3GTLA 4D3YA 1YNJD 3GTMA 3DU5A 2WAQA 3GTQA 2E2HA 3LF9A 4F3EA 1RR8C 3K5NA 2A6HD 1ISEA 2A69D 2NVYA 1I50A 4AN8A 1R9TA 3GTGA 5CQGA 2NVXA 1V9MA 2R4GA 4AHCA 4IP9A 2B63A 1YNND 4D3ZA 1WQFA 1Y1WA 1SEUA 4KC6A 1K4SA 3GTKA 4KB4A 3FKIA 3K5LA 2R7ZA 1WQGA 1TWHA 1I6VD 1Q8IA 3IAYA 3HKZA 1A35A 2YU9A 1EH1A 1TWAA 3H0GA 1R5ZA 4C2MA 1R49A 4JLRC 5JSBB 3MAQA 4AYBA 4KB2A 3GTJA 4LMOA 4NOMA 5C9HA 2BE5D 1K4TA 1LPQA 2WB1A 1NH3A 4O26A 3K5OA 1TWFA 4IP8A 1A31A 2Y0SA 3P9AA 2O5JD 3CQZA 1IS1A 4KAWX 3K58A 3GTPA 4FXDA 4FYDA 4L8IA 1TWGA 3DU6A 1EJ9A 5JSNB 1WQHA 4GFQA 1TL8A 2F4QA 1K83A 1WCMA 2CW0D 1HQMD 2B9SB 1ZYRD 2VUMA 1TGOA 1Y1VA 1T8IA 4Q5VA 2PMZA 1SMYD 4NOKA 3K59A 1GE9A 1TWCA 2JA7A 2A68D 1MIUA 4KDDA 4QCLA 4FGUA 1A36A 2R93A 2E2IA 4Q5GA 1DD5A 4EJ3A 2JA6A 2JA5A 3WVOA 1I3QA 3M4AA 3K57A 3GTOA 1RRJA 4OYDB 1SFOA 1IW7D 3K5MA 3LHPS 3SJRA 4QIWA 3KYLA 1EK8A 4H3TA 5MLC9 4NOLA 2R92A 1Y698 1SC7A 2A6ED
chains in the Genus database with same CATH topology
3GTLA 4D3YA 1YNJD 3GTMA 3DU5A 2WAQA 3GTQA 2E2HA 3LF9A 4F3EA 1RR8C 3K5NA 2A6HD 1ISEA 2A69D 2NVYA 1I50A 4AN8A 1R9TA 3GTGA 5CQGA 2NVXA 1V9MA 2R4GA 4AHCA 4IP9A 2B63A 1YNND 4D3ZA 1WQFA 1Y1WA 1SEUA 4KC6A 1K4SA 3GTKA 4KB4A 3FKIA 3K5LA 2R7ZA 1WQGA 1TWHA 1I6VD 1Q8IA 3IAYA 3HKZA 1A35A 2YU9A 1EH1A 1TWAA 3H0GA 1R5ZA 4C2MA 1R49A 4JLRC 5JSBB 3MAQA 4AYBA 4KB2A 3GTJA 4LMOA 4NOMA 5C9HA 2BE5D 1K4TA 1LPQA 2WB1A 1NH3A 4O26A 3K5OA 1TWFA 4IP8A 1A31A 2Y0SA 3P9AA 2O5JD 3CQZA 1IS1A 4KAWX 3K58A 3GTPA 4FXDA 4FYDA 4L8IA 1TWGA 3DU6A 1EJ9A 5JSNB 1WQHA 4GFQA 1TL8A 2F4QA 1K83A 1WCMA 2CW0D 1HQMD 2B9SB 1ZYRD 2VUMA 1TGOA 1Y1VA 1T8IA 4Q5VA 2PMZA 1SMYD 4NOKA 3K59A 1GE9A 1TWCA 2JA7A 2A68D 1MIUA 4KDDA 4QCLA 4FGUA 1A36A 2R93A 2E2IA 4Q5GA 1DD5A 4EJ3A 2JA6A 2JA5A 3WVOA 1I3QA 3M4AA 3K57A 3GTOA 1RRJA 4OYDB 1SFOA 1IW7D 3K5MA 3LHPS 3SJRA 4QIWA 3KYLA 1EK8A 4H3TA 5MLC9 4NOLA 2R92A 1Y698 1SC7A 2A6ED
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WQG A;  1DD5 A;  4L8I A;  1EH1 A;  4GFQ A;  1WQH A;  3LF9 A;  5JSN B;  4JLR C;  4OYD B;  5JSB B;  1ISE A;  4KB2 A;  3LHP S;  1EK8 A;  1GE9 A;  5MLC 9;  1WQF A;  1Y69 8;  4KC6 A;  4KB4 A;  4KDD A;  1IS1 A;  4KAW X; 
#chains in the Genus database with same CATH topology
 3GTL A;  4D3Y A;  1YNJ D;  3GTM A;  3DU5 A;  2WAQ A;  3GTQ A;  2E2H A;  3LF9 A;  4F3E A;  1RR8 C;  3K5N A;  2A6H D;  1ISE A;  2A69 D;  2NVY A;  1I50 A;  4AN8 A;  1R9T A;  3GTG A;  5CQG A;  2NVX A;  1V9M A;  2R4G A;  4AHC A;  4IP9 A;  2B63 A;  1YNN D;  4D3Z A;  1WQF A;  1Y1W A;  1SEU A;  4KC6 A;  1K4S A;  3GTK A;  4KB4 A;  3FKI A;  3K5L A;  2R7Z A;  1WQG A;  1TWH A;  1I6V D;  1Q8I A;  3IAY A;  3HKZ A;  1A35 A;  2YU9 A;  1EH1 A;  1TWA A;  3H0G A;  1R5Z A;  4C2M A;  1R49 A;  4JLR C;  5JSB B;  3MAQ A;  4AYB A;  4KB2 A;  3GTJ A;  4LMO A;  4NOM A;  5C9H A;  2BE5 D;  1K4T A;  1LPQ A;  2WB1 A;  1NH3 A;  4O26 A;  3K5O A;  1TWF A;  4IP8 A;  1A31 A;  2Y0S A;  3P9A A;  2O5J D;  3CQZ A;  1IS1 A;  4KAW X;  3K58 A;  3GTP A;  4FXD A;  4FYD A;  4L8I A;  1TWG A;  3DU6 A;  1EJ9 A;  5JSN B;  1WQH A;  4GFQ A;  1TL8 A;  2F4Q A;  1K83 A;  1WCM A;  2CW0 D;  1HQM D;  2B9S B;  1ZYR D;  2VUM A;  1TGO A;  1Y1V A;  1T8I A;  4Q5V A;  2PMZ A;  1SMY D;  4NOK A;  3K59 A;  1GE9 A;  1TWC A;  2JA7 A;  2A68 D;  1MIU A;  4KDD A;  4QCL A;  4FGU A;  1A36 A;  2R93 A;  2E2I A;  4Q5G A;  1DD5 A;  4EJ3 A;  2JA6 A;  2JA5 A;  3WVO A;  1I3Q A;  3M4A A;  3K57 A;  3GTO A;  1RRJ A;  4OYD B;  1SFO A;  1IW7 D;  3K5M A;  3LHP S;  3SJR A;  4QIW A;  3KYL A;  1EK8 A;  4H3T A;  5MLC 9;  4NOL A;  2R92 A;  1Y69 8;  1SC7 A;  2A6E D; 
#chains in the Genus database with same CATH homology
 3GTL A;  4D3Y A;  1YNJ D;  3GTM A;  3DU5 A;  2WAQ A;  3GTQ A;  2E2H A;  3LF9 A;  4F3E A;  1RR8 C;  3K5N A;  2A6H D;  1ISE A;  2A69 D;  2NVY A;  1I50 A;  4AN8 A;  1R9T A;  3GTG A;  5CQG A;  2NVX A;  1V9M A;  2R4G A;  4AHC A;  4IP9 A;  2B63 A;  1YNN D;  4D3Z A;  1WQF A;  1Y1W A;  1SEU A;  4KC6 A;  1K4S A;  3GTK A;  4KB4 A;  3FKI A;  3K5L A;  2R7Z A;  1WQG A;  1TWH A;  1I6V D;  1Q8I A;  3IAY A;  3HKZ A;  1A35 A;  2YU9 A;  1EH1 A;  1TWA A;  3H0G A;  1R5Z A;  4C2M A;  1R49 A;  4JLR C;  5JSB B;  3MAQ A;  4AYB A;  4KB2 A;  3GTJ A;  4LMO A;  4NOM A;  5C9H A;  2BE5 D;  1K4T A;  1LPQ A;  2WB1 A;  1NH3 A;  4O26 A;  3K5O A;  1TWF A;  4IP8 A;  1A31 A;  2Y0S A;  3P9A A;  2O5J D;  3CQZ A;  1IS1 A;  4KAW X;  3K58 A;  3GTP A;  4FXD A;  4FYD A;  4L8I A;  1TWG A;  3DU6 A;  1EJ9 A;  5JSN B;  1WQH A;  4GFQ A;  1TL8 A;  2F4Q A;  1K83 A;  1WCM A;  2CW0 D;  1HQM D;  2B9S B;  1ZYR D;  2VUM A;  1TGO A;  1Y1V A;  1T8I A;  4Q5V A;  2PMZ A;  1SMY D;  4NOK A;  3K59 A;  1GE9 A;  1TWC A;  2JA7 A;  2A68 D;  1MIU A;  4KDD A;  4QCL A;  4FGU A;  1A36 A;  2R93 A;  2E2I A;  4Q5G A;  1DD5 A;  4EJ3 A;  2JA6 A;  2JA5 A;  3WVO A;  1I3Q A;  3M4A A;  3K57 A;  3GTO A;  1RRJ A;  4OYD B;  1SFO A;  1IW7 D;  3K5M A;  3LHP S;  3SJR A;  4QIW A;  3KYL A;  1EK8 A;  4H3T A;  5MLC 9;  4NOL A;  2R92 A;  1Y69 8;  1SC7 A;  2A6E D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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