The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
176
|
sequence length |
596
|
structure length |
596
|
Chain Sequence |
MVHYYRLSLKSRQKAPKIVNSKYNSILNIALKNFRLCKKHKTKKPVQILALLQEIIPKSYFGTTTNLKRFYKVVEKILTQSSFECIHLSVLHKCYDYDAIPWLQNVEPNLRPKLLLKHNLFLLDNIVKPIIAFYYKPIKTLNGHEIKFIRKEEYISFESKVFHKLKKMKYLVEVQDEVKPRGVLNIIPKQDNFRAIVSIFPDSARKPFFKLLTSKIYKVLEEKYKTSGSLYTCWSEFTQKTQGQIYGIKVDIRDAYGNVKIPVLCKLIQSIPTHLLDSEKKNFIVDHISNQFVAFRRKIYKWNHGLLQGDPLSGCLCELYMAFMDRLYFSNLDKDAFIHRTVDDYFFCSPHPHKVYDFELLIKGVYQVNPTKTRTNLPTHRHPQDEIPYCGKIFNLTTRQVRTLYKLPPNYEIRHKFKLWNFNNQISDDNPARFLQKAMDFPFICNSFTKFEFNTVFNDQRTVFANFYDAMICVAYKFDAAMMALRTSFLVNDFGFIWLVLSSTVRAYASRAFKKIVTYKGGKYRKVTFQCLKSIAWRAFLAVLKRRTEIYKGLIDRIKSREKLTMKFHDGEVDASYFCKLPEKFRFVKINRKASI
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
Telomerase reverse transcriptase
|
| publication title |
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA.
pubmed doi rcsb |
| source organism |
Tribolium castaneum
|
| molecule tags |
Nucleic acid binding protein/dna/rna
|
| total genus |
176
|
| structure length |
596
|
| sequence length |
596
|
| ec nomenclature | |
| pdb deposition date | 2009-12-06 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) |
| A | PF12009 | Telomerase_RBD | Telomerase ribonucleoprotein complex - RNA binding domain |
| A | PF17984 | TERT_thumb | Telomerase reverse transcriptase thumb DNA binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Arc Repressor Mutant, subunit A | ||
| Mainly Alpha | Orthogonal Bundle | Topoisomerase I; Chain A, domain 4 | Topoisomerase I; Chain A, domain 4 | ||
| Mainly Alpha | Orthogonal Bundle | Tetracycline Repressor; domain 2 | Tetracycline Repressor; domain 2 | ||
| Alpha Beta | Roll | HIV Type 1 Reverse Transcriptase; Chain A, domain 1 | HIV Type 1 Reverse Transcriptase; Chain A, domain 1 | ||
| Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Alpha-Beta Plaits |
