4O26A

Crystal structure of the trbd domain of tert and the cr4/5 of tr
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
257
structure length
240
Chain Sequence
GSGFLYGGRGMHGFCLNRKRRTAAGPRRLQGQDLVRLVFFEGLKPKKLPLRYFNMVPVFGRLLQRHRKCRYSSVLHRMCPVVELSRAAQGELSSLIPQHCAPHRVYLFVRECLTAVVPEELWGSDHNRLQFFSRVRGFLKSGSVAELMWKIKVMDCDWLKLRRTAGRFPPSELAYRTRILSQFLTWLLDGFVVGLVRACFYATESNAIRFYRQEVWSKLQDLAFRRHIAKGEMEELSPAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for protein-RNA recognition in telomerase.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Oryzias latipes
molecule keywords Telomerase reverse transcriptase
total genus 76
structure length 240
sequence length 257
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2013-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12009 Telomerase_RBD Telomerase ribonucleoprotein complex - RNA binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.70 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4o26A00
3DU6A 2R4GA 3KYLA 5CQGA 5C9HA 4LMOA 4O26A 3DU5A
chains in the Genus database with same CATH superfamily
1A35A 4KC6A 2E2IA 3H0GA 5JSBB 3P9AA 2F4QA 2WAQA 1WCMA 1WQGA 1Y698 2B9SB 4EJ3A 4NOLA 3KYLA 1TL8A 3M4AA 3CQZA 4IP8A 3K57A 2WB1A 4AN8A 1R5ZA 4JLRC 2R4GA 1HQMD 3K5LA 1TWHA 1NH3A 2BE5D 2E2HA 4LMOA 1DD5A 2NVYA 3GTQA 4OYDB 1I6VD 2A6ED 1RRJA 1IS1A 4AHCA 5JSNB 1TGOA 3K5OA 4F3EA 2B63A 3GTKA 4AYBA 1A31A 4D3ZA 1SEUA 4IP9A 1R9TA 4O26A 3SJRA 1K83A 4D3YA 2O5JD 1GE9A 1EK8A 3DU5A 3IAYA 4Q5VA 1K4SA 1T8IA 1ZYRD 4L8IA 3K5MA 2R93A 5C9HA 4C2MA 1RR8C 1EH1A 1Y1VA 2Y0SA 4Q5GA 3GTPA 1K4TA 3HKZA 4QIWA 3WVOA 2JA7A 1TWFA 4FGUA 5CQGA 1MIUA 1I3QA 4GFQA 3GTOA 4FYDA 1I50A 1WQHA 3LHPS 4KAWX 1IW7D 2A68D 1SMYD 2NVXA 3GTJA 4KB4A 4FXDA 4QCLA 1SFOA 2JA6A 1Y1WA 1YNJD 1YNND 2PMZA 2R7ZA 4KDDA 3MAQA 1SC7A 1TWGA 1WQFA 1TWAA 1V9MA 3FKIA 2YU9A 3K58A 1Q8IA 4NOKA 1TWCA 3GTMA 3K5NA 2R92A 1ISEA 3LF9A 1LPQA 4KB2A 3K59A 2A6HD 2VUMA 3GTGA 5MLC9 2CW0D 4NOMA 3DU6A 1EJ9A 1A36A 4H3TA 2JA5A 1R49A 3GTLA 2A69D
chains in the Genus database with same CATH topology
1A35A 4KC6A 2E2IA 3H0GA 5JSBB 3P9AA 2F4QA 2WAQA 1WCMA 1WQGA 1Y698 2B9SB 4EJ3A 4NOLA 3KYLA 1TL8A 3M4AA 3CQZA 4IP8A 3K57A 2WB1A 4AN8A 1R5ZA 4JLRC 2R4GA 1HQMD 3K5LA 1TWHA 1NH3A 2BE5D 2E2HA 4LMOA 1DD5A 2NVYA 3GTQA 4OYDB 1I6VD 2A6ED 1RRJA 1IS1A 4AHCA 5JSNB 1TGOA 3K5OA 4F3EA 2B63A 3GTKA 4AYBA 1A31A 4D3ZA 1SEUA 4IP9A 1R9TA 4O26A 3SJRA 1K83A 4D3YA 2O5JD 1GE9A 1EK8A 3DU5A 3IAYA 4Q5VA 1K4SA 1T8IA 1ZYRD 4L8IA 3K5MA 2R93A 5C9HA 4C2MA 1RR8C 1EH1A 1Y1VA 2Y0SA 4Q5GA 3GTPA 1K4TA 3HKZA 4QIWA 3WVOA 2JA7A 1TWFA 4FGUA 5CQGA 1MIUA 1I3QA 4GFQA 3GTOA 4FYDA 1I50A 1WQHA 3LHPS 4KAWX 1IW7D 2A68D 1SMYD 2NVXA 3GTJA 4KB4A 4FXDA 4QCLA 1SFOA 2JA6A 1Y1WA 1YNJD 1YNND 2PMZA 2R7ZA 4KDDA 3MAQA 1SC7A 1TWGA 1WQFA 1TWAA 1V9MA 3FKIA 2YU9A 3K58A 1Q8IA 4NOKA 1TWCA 3GTMA 3K5NA 2R92A 1ISEA 3LF9A 1LPQA 4KB2A 3K59A 2A6HD 2VUMA 3GTGA 5MLC9 2CW0D 4NOMA 3DU6A 1EJ9A 1A36A 4H3TA 2JA5A 1R49A 3GTLA 2A69D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DU6 A;  2R4G A;  3KYL A;  5CQG A;  5C9H A;  4LMO A;  4O26 A;  3DU5 A; 
#chains in the Genus database with same CATH topology
 1A35 A;  4KC6 A;  2E2I A;  3H0G A;  5JSB B;  3P9A A;  2F4Q A;  2WAQ A;  1WCM A;  1WQG A;  1Y69 8;  2B9S B;  4EJ3 A;  4NOL A;  3KYL A;  1TL8 A;  3M4A A;  3CQZ A;  4IP8 A;  3K57 A;  2WB1 A;  4AN8 A;  1R5Z A;  4JLR C;  2R4G A;  1HQM D;  3K5L A;  1TWH A;  1NH3 A;  2BE5 D;  2E2H A;  4LMO A;  1DD5 A;  2NVY A;  3GTQ A;  4OYD B;  1I6V D;  2A6E D;  1RRJ A;  1IS1 A;  4AHC A;  5JSN B;  1TGO A;  3K5O A;  4F3E A;  2B63 A;  3GTK A;  4AYB A;  1A31 A;  4D3Z A;  1SEU A;  4IP9 A;  1R9T A;  4O26 A;  3SJR A;  1K83 A;  4D3Y A;  2O5J D;  1GE9 A;  1EK8 A;  3DU5 A;  3IAY A;  4Q5V A;  1K4S A;  1T8I A;  1ZYR D;  4L8I A;  3K5M A;  2R93 A;  5C9H A;  4C2M A;  1RR8 C;  1EH1 A;  1Y1V A;  2Y0S A;  4Q5G A;  3GTP A;  1K4T A;  3HKZ A;  4QIW A;  3WVO A;  2JA7 A;  1TWF A;  4FGU A;  5CQG A;  1MIU A;  1I3Q A;  4GFQ A;  3GTO A;  4FYD A;  1I50 A;  1WQH A;  3LHP S;  4KAW X;  1IW7 D;  2A68 D;  1SMY D;  2NVX A;  3GTJ A;  4KB4 A;  4FXD A;  4QCL A;  1SFO A;  2JA6 A;  1Y1W A;  1YNJ D;  1YNN D;  2PMZ A;  2R7Z A;  4KDD A;  3MAQ A;  1SC7 A;  1TWG A;  1WQF A;  1TWA A;  1V9M A;  3FKI A;  2YU9 A;  3K58 A;  1Q8I A;  4NOK A;  1TWC A;  3GTM A;  3K5N A;  2R92 A;  1ISE A;  3LF9 A;  1LPQ A;  4KB2 A;  3K59 A;  2A6H D;  2VUM A;  3GTG A;  5MLC 9;  2CW0 D;  4NOM A;  3DU6 A;  1EJ9 A;  1A36 A;  4H3T A;  2JA5 A;  1R49 A;  3GTL A;  2A69 D; 
#chains in the Genus database with same CATH homology
 1A35 A;  4KC6 A;  2E2I A;  3H0G A;  5JSB B;  3P9A A;  2F4Q A;  2WAQ A;  1WCM A;  1WQG A;  1Y69 8;  2B9S B;  4EJ3 A;  4NOL A;  3KYL A;  1TL8 A;  3M4A A;  3CQZ A;  4IP8 A;  3K57 A;  2WB1 A;  4AN8 A;  1R5Z A;  4JLR C;  2R4G A;  1HQM D;  3K5L A;  1TWH A;  1NH3 A;  2BE5 D;  2E2H A;  4LMO A;  1DD5 A;  2NVY A;  3GTQ A;  4OYD B;  1I6V D;  2A6E D;  1RRJ A;  1IS1 A;  4AHC A;  5JSN B;  1TGO A;  3K5O A;  4F3E A;  2B63 A;  3GTK A;  4AYB A;  1A31 A;  4D3Z A;  1SEU A;  4IP9 A;  1R9T A;  4O26 A;  3SJR A;  1K83 A;  4D3Y A;  2O5J D;  1GE9 A;  1EK8 A;  3DU5 A;  3IAY A;  4Q5V A;  1K4S A;  1T8I A;  1ZYR D;  4L8I A;  3K5M A;  2R93 A;  5C9H A;  4C2M A;  1RR8 C;  1EH1 A;  1Y1V A;  2Y0S A;  4Q5G A;  3GTP A;  1K4T A;  3HKZ A;  4QIW A;  3WVO A;  2JA7 A;  1TWF A;  4FGU A;  5CQG A;  1MIU A;  1I3Q A;  4GFQ A;  3GTO A;  4FYD A;  1I50 A;  1WQH A;  3LHP S;  4KAW X;  1IW7 D;  2A68 D;  1SMY D;  2NVX A;  3GTJ A;  4KB4 A;  4FXD A;  4QCL A;  1SFO A;  2JA6 A;  1Y1W A;  1YNJ D;  1YNN D;  2PMZ A;  2R7Z A;  4KDD A;  3MAQ A;  1SC7 A;  1TWG A;  1WQF A;  1TWA A;  1V9M A;  3FKI A;  2YU9 A;  3K58 A;  1Q8I A;  4NOK A;  1TWC A;  3GTM A;  3K5N A;  2R92 A;  1ISE A;  3LF9 A;  1LPQ A;  4KB2 A;  3K59 A;  2A6H D;  2VUM A;  3GTG A;  5MLC 9;  2CW0 D;  4NOM A;  3DU6 A;  1EJ9 A;  1A36 A;  4H3T A;  2JA5 A;  1R49 A;  3GTL A;  2A69 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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