4IP8A

Structure of human serum amyloid a1
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
105
structure length
105
Chain Sequence
MRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 47
structure length 105
sequence length 105
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip8A00
4IP9A 4IP8A 4Q5GA
chains in the Genus database with same CATH superfamily
1TWGA 3K57A 1YNND 4EJ3A 1Q8IA 4AN8A 3FKIA 4GFQA 3GTQA 1WQGA 4FGUA 1IS1A 4FXDA 1WQHA 1A36A 1A35A 2YU9A 2E2IA 3SJRA 3K5LA 2JA6A 5MLC9 4IP9A 2Y0SA 1ZYRD 1DD5A 3K5MA 2WAQA 1Y698 2B63A 2JA7A 1TWHA 4NOLA 1Y1WA 4AHCA 2A6ED 1I3QA 2NVXA 3M4AA 3GTLA 3KYLA 4NOKA 3MAQA 4KB2A 3GTJA 4JLRC 1RR8C 1TWFA 1RRJA 2VUMA 2R4GA 1SEUA 4KC6A 1GE9A 4IP8A 1K4TA 4D3YA 4D3ZA 2JA5A 1WCMA 3WVOA 2A6HD 3K5NA 3P9AA 4Q5GA 1R5ZA 1WQFA 3K5OA 2WB1A 4C2MA 3LHPS 1I6VD 4KDDA 5JSBB 2E2HA 3DU6A 4F3EA 2R93A 5JSNB 3GTOA 3HKZA 4LMOA 4Q5VA 4QCLA 1TL8A 2R92A 4L8IA 3GTPA 2O5JD 4KB4A 2BE5D 1SC7A 2NVYA 1R9TA 3GTKA 4NOMA 3GTMA 1T8IA 1SFOA 4QIWA 1K4SA 3K59A 4OYDB 1TWAA 1A31A 4O26A 5C9HA 3LF9A 1LPQA 1EJ9A 5CQGA 1EH1A 2PMZA 1I50A 4H3TA 1YNJD 3CQZA 3GTGA 2CW0D 2F4QA 1TGOA 1EK8A 3IAYA 1ISEA 2R7ZA 4AYBA 4KAWX 3H0GA 2B9SB 1K83A 1NH3A 1IW7D 1R49A 2A69D 1Y1VA 1MIUA 4FYDA 1V9MA 1HQMD 3DU5A 3K58A 1TWCA 2A68D 1SMYD
chains in the Genus database with same CATH topology
1TWGA 3K57A 1YNND 4EJ3A 1Q8IA 4AN8A 3FKIA 4GFQA 3GTQA 1WQGA 4FGUA 1IS1A 4FXDA 1WQHA 1A36A 1A35A 2YU9A 2E2IA 3SJRA 3K5LA 2JA6A 5MLC9 4IP9A 2Y0SA 1ZYRD 1DD5A 3K5MA 2WAQA 1Y698 2B63A 2JA7A 1TWHA 4NOLA 1Y1WA 4AHCA 2A6ED 1I3QA 2NVXA 3M4AA 3GTLA 3KYLA 4NOKA 3MAQA 4KB2A 3GTJA 4JLRC 1RR8C 1TWFA 1RRJA 2VUMA 2R4GA 1SEUA 4KC6A 1GE9A 4IP8A 1K4TA 4D3YA 4D3ZA 2JA5A 1WCMA 3WVOA 2A6HD 3K5NA 3P9AA 4Q5GA 1R5ZA 1WQFA 3K5OA 2WB1A 4C2MA 3LHPS 1I6VD 4KDDA 5JSBB 2E2HA 3DU6A 4F3EA 2R93A 5JSNB 3GTOA 3HKZA 4LMOA 4Q5VA 4QCLA 1TL8A 2R92A 4L8IA 3GTPA 2O5JD 4KB4A 2BE5D 1SC7A 2NVYA 1R9TA 3GTKA 4NOMA 3GTMA 1T8IA 1SFOA 4QIWA 1K4SA 3K59A 4OYDB 1TWAA 1A31A 4O26A 5C9HA 3LF9A 1LPQA 1EJ9A 5CQGA 1EH1A 2PMZA 1I50A 4H3TA 1YNJD 3CQZA 3GTGA 2CW0D 2F4QA 1TGOA 1EK8A 3IAYA 1ISEA 2R7ZA 4AYBA 4KAWX 3H0GA 2B9SB 1K83A 1NH3A 1IW7D 1R49A 2A69D 1Y1VA 1MIUA 4FYDA 1V9MA 1HQMD 3DU5A 3K58A 1TWCA 2A68D 1SMYD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP9 A;  4IP8 A;  4Q5G A; 
#chains in the Genus database with same CATH topology
 1TWG A;  3K57 A;  1YNN D;  4EJ3 A;  1Q8I A;  4AN8 A;  3FKI A;  4GFQ A;  3GTQ A;  1WQG A;  4FGU A;  1IS1 A;  4FXD A;  1WQH A;  1A36 A;  1A35 A;  2YU9 A;  2E2I A;  3SJR A;  3K5L A;  2JA6 A;  5MLC 9;  4IP9 A;  2Y0S A;  1ZYR D;  1DD5 A;  3K5M A;  2WAQ A;  1Y69 8;  2B63 A;  2JA7 A;  1TWH A;  4NOL A;  1Y1W A;  4AHC A;  2A6E D;  1I3Q A;  2NVX A;  3M4A A;  3GTL A;  3KYL A;  4NOK A;  3MAQ A;  4KB2 A;  3GTJ A;  4JLR C;  1RR8 C;  1TWF A;  1RRJ A;  2VUM A;  2R4G A;  1SEU A;  4KC6 A;  1GE9 A;  4IP8 A;  1K4T A;  4D3Y A;  4D3Z A;  2JA5 A;  1WCM A;  3WVO A;  2A6H D;  3K5N A;  3P9A A;  4Q5G A;  1R5Z A;  1WQF A;  3K5O A;  2WB1 A;  4C2M A;  3LHP S;  1I6V D;  4KDD A;  5JSB B;  2E2H A;  3DU6 A;  4F3E A;  2R93 A;  5JSN B;  3GTO A;  3HKZ A;  4LMO A;  4Q5V A;  4QCL A;  1TL8 A;  2R92 A;  4L8I A;  3GTP A;  2O5J D;  4KB4 A;  2BE5 D;  1SC7 A;  2NVY A;  1R9T A;  3GTK A;  4NOM A;  3GTM A;  1T8I A;  1SFO A;  4QIW A;  1K4S A;  3K59 A;  4OYD B;  1TWA A;  1A31 A;  4O26 A;  5C9H A;  3LF9 A;  1LPQ A;  1EJ9 A;  5CQG A;  1EH1 A;  2PMZ A;  1I50 A;  4H3T A;  1YNJ D;  3CQZ A;  3GTG A;  2CW0 D;  2F4Q A;  1TGO A;  1EK8 A;  3IAY A;  1ISE A;  2R7Z A;  4AYB A;  4KAW X;  3H0G A;  2B9S B;  1K83 A;  1NH3 A;  1IW7 D;  1R49 A;  2A69 D;  1Y1V A;  1MIU A;  4FYD A;  1V9M A;  1HQM D;  3DU5 A;  3K58 A;  1TWC A;  2A68 D;  1SMY D; 
#chains in the Genus database with same CATH homology
 1TWG A;  3K57 A;  1YNN D;  4EJ3 A;  1Q8I A;  4AN8 A;  3FKI A;  4GFQ A;  3GTQ A;  1WQG A;  4FGU A;  1IS1 A;  4FXD A;  1WQH A;  1A36 A;  1A35 A;  2YU9 A;  2E2I A;  3SJR A;  3K5L A;  2JA6 A;  5MLC 9;  4IP9 A;  2Y0S A;  1ZYR D;  1DD5 A;  3K5M A;  2WAQ A;  1Y69 8;  2B63 A;  2JA7 A;  1TWH A;  4NOL A;  1Y1W A;  4AHC A;  2A6E D;  1I3Q A;  2NVX A;  3M4A A;  3GTL A;  3KYL A;  4NOK A;  3MAQ A;  4KB2 A;  3GTJ A;  4JLR C;  1RR8 C;  1TWF A;  1RRJ A;  2VUM A;  2R4G A;  1SEU A;  4KC6 A;  1GE9 A;  4IP8 A;  1K4T A;  4D3Y A;  4D3Z A;  2JA5 A;  1WCM A;  3WVO A;  2A6H D;  3K5N A;  3P9A A;  4Q5G A;  1R5Z A;  1WQF A;  3K5O A;  2WB1 A;  4C2M A;  3LHP S;  1I6V D;  4KDD A;  5JSB B;  2E2H A;  3DU6 A;  4F3E A;  2R93 A;  5JSN B;  3GTO A;  3HKZ A;  4LMO A;  4Q5V A;  4QCL A;  1TL8 A;  2R92 A;  4L8I A;  3GTP A;  2O5J D;  4KB4 A;  2BE5 D;  1SC7 A;  2NVY A;  1R9T A;  3GTK A;  4NOM A;  3GTM A;  1T8I A;  1SFO A;  4QIW A;  1K4S A;  3K59 A;  4OYD B;  1TWA A;  1A31 A;  4O26 A;  5C9H A;  3LF9 A;  1LPQ A;  1EJ9 A;  5CQG A;  1EH1 A;  2PMZ A;  1I50 A;  4H3T A;  1YNJ D;  3CQZ A;  3GTG A;  2CW0 D;  2F4Q A;  1TGO A;  1EK8 A;  3IAY A;  1ISE A;  2R7Z A;  4AYB A;  4KAW X;  3H0G A;  2B9S B;  1K83 A;  1NH3 A;  1IW7 D;  1R49 A;  2A69 D;  1Y1V A;  1MIU A;  4FYD A;  1V9M A;  1HQM D;  3DU5 A;  3K58 A;  1TWC A;  2A68 D;  1SMY D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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