4IP8A

Structure of human serum amyloid a1
Total Genus 47
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
105
structure length
105
Chain Sequence
MRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 47
structure length 105
sequence length 105
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip8A00
4IP9A 4IP8A 4Q5GA
chains in the Genus database with same CATH superfamily
1RRJA 1WQFA 4QIWA 3MAQA 2O5JD 5MLC9 3HKZA 1K83A 2JA7A 1SEUA 2A6HD 1I3QA 1IW7D 1R49A 1TWAA 1YNJD 3GTMA 3K5NA 3K58A 3K57A 4KDDA 3GTQA 1ISEA 3WVOA 3SJRA 4EJ3A 4C2MA 4OYDB 2YU9A 1T8IA 3K5OA 1Q8IA 1MIUA 1SC7A 1EJ9A 3GTKA 1WQHA 3GTLA 2R93A 1TL8A 2R4GA 4FGUA 5JSBB 1K4TA 1I50A 2WAQA 4F3EA 4NOLA 4AYBA 1TWHA 4KAWX 1LPQA 4NOMA 1SFOA 2A69D 2B9SB 3H0GA 2NVYA 4IP8A 1Y698 1TGOA 3P9AA 4GFQA 1ZYRD 2Y0SA 2E2HA 4D3YA 1YNND 1A31A 4LMOA 1R9TA 4D3ZA 4KB2A 3DU5A 3LF9A 4O26A 3IAYA 1TWCA 2CW0D 1I6VD 2WB1A 2F4QA 2A6ED 3LHPS 5C9HA 5JSNB 2BE5D 2NVXA 1IS1A 4IP9A 3CQZA 1R5ZA 1GE9A 1Y1WA 1Y1VA 3GTGA 1HQMD 1A36A 4AN8A 3GTOA 4NOKA 1K4SA 1RR8C 2VUMA 5CQGA 1EH1A 4QCLA 3FKIA 1TWFA 4H3TA 2B63A 1V9MA 1NH3A 1EK8A 3K5MA 2JA5A 4FYDA 1WQGA 4KC6A 3GTJA 4KB4A 2PMZA 2R92A 4L8IA 4AHCA 2R7ZA 3K59A 1SMYD 3M4AA 3DU6A 1WCMA 4Q5GA 3K5LA 3KYLA 1DD5A 4Q5VA 2A68D 1A35A 2JA6A 1TWGA 3GTPA 2E2IA 4FXDA 4JLRC
chains in the Genus database with same CATH topology
1RRJA 1WQFA 4QIWA 3MAQA 2O5JD 5MLC9 3HKZA 1K83A 2JA7A 1SEUA 2A6HD 1I3QA 1IW7D 1R49A 1TWAA 1YNJD 3GTMA 3K5NA 3K58A 3K57A 4KDDA 3GTQA 1ISEA 3WVOA 3SJRA 4EJ3A 4C2MA 4OYDB 2YU9A 1T8IA 3K5OA 1Q8IA 1MIUA 1SC7A 1EJ9A 3GTKA 1WQHA 3GTLA 2R93A 1TL8A 2R4GA 4FGUA 5JSBB 1K4TA 1I50A 2WAQA 4F3EA 4NOLA 4AYBA 1TWHA 4KAWX 1LPQA 4NOMA 1SFOA 2A69D 2B9SB 3H0GA 2NVYA 4IP8A 1Y698 1TGOA 3P9AA 4GFQA 1ZYRD 2Y0SA 2E2HA 4D3YA 1YNND 1A31A 4LMOA 1R9TA 4D3ZA 4KB2A 3DU5A 3LF9A 4O26A 3IAYA 1TWCA 2CW0D 1I6VD 2WB1A 2F4QA 2A6ED 3LHPS 5C9HA 5JSNB 2BE5D 2NVXA 1IS1A 4IP9A 3CQZA 1R5ZA 1GE9A 1Y1WA 1Y1VA 3GTGA 1HQMD 1A36A 4AN8A 3GTOA 4NOKA 1K4SA 1RR8C 2VUMA 5CQGA 1EH1A 4QCLA 3FKIA 1TWFA 4H3TA 2B63A 1V9MA 1NH3A 1EK8A 3K5MA 2JA5A 4FYDA 1WQGA 4KC6A 3GTJA 4KB4A 2PMZA 2R92A 4L8IA 4AHCA 2R7ZA 3K59A 1SMYD 3M4AA 3DU6A 1WCMA 4Q5GA 3K5LA 3KYLA 1DD5A 4Q5VA 2A68D 1A35A 2JA6A 1TWGA 3GTPA 2E2IA 4FXDA 4JLRC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP9 A;  4IP8 A;  4Q5G A; 
#chains in the Genus database with same CATH topology
 1RRJ A;  1WQF A;  4QIW A;  3MAQ A;  2O5J D;  5MLC 9;  3HKZ A;  1K83 A;  2JA7 A;  1SEU A;  2A6H D;  1I3Q A;  1IW7 D;  1R49 A;  1TWA A;  1YNJ D;  3GTM A;  3K5N A;  3K58 A;  3K57 A;  4KDD A;  3GTQ A;  1ISE A;  3WVO A;  3SJR A;  4EJ3 A;  4C2M A;  4OYD B;  2YU9 A;  1T8I A;  3K5O A;  1Q8I A;  1MIU A;  1SC7 A;  1EJ9 A;  3GTK A;  1WQH A;  3GTL A;  2R93 A;  1TL8 A;  2R4G A;  4FGU A;  5JSB B;  1K4T A;  1I50 A;  2WAQ A;  4F3E A;  4NOL A;  4AYB A;  1TWH A;  4KAW X;  1LPQ A;  4NOM A;  1SFO A;  2A69 D;  2B9S B;  3H0G A;  2NVY A;  4IP8 A;  1Y69 8;  1TGO A;  3P9A A;  4GFQ A;  1ZYR D;  2Y0S A;  2E2H A;  4D3Y A;  1YNN D;  1A31 A;  4LMO A;  1R9T A;  4D3Z A;  4KB2 A;  3DU5 A;  3LF9 A;  4O26 A;  3IAY A;  1TWC A;  2CW0 D;  1I6V D;  2WB1 A;  2F4Q A;  2A6E D;  3LHP S;  5C9H A;  5JSN B;  2BE5 D;  2NVX A;  1IS1 A;  4IP9 A;  3CQZ A;  1R5Z A;  1GE9 A;  1Y1W A;  1Y1V A;  3GTG A;  1HQM D;  1A36 A;  4AN8 A;  3GTO A;  4NOK A;  1K4S A;  1RR8 C;  2VUM A;  5CQG A;  1EH1 A;  4QCL A;  3FKI A;  1TWF A;  4H3T A;  2B63 A;  1V9M A;  1NH3 A;  1EK8 A;  3K5M A;  2JA5 A;  4FYD A;  1WQG A;  4KC6 A;  3GTJ A;  4KB4 A;  2PMZ A;  2R92 A;  4L8I A;  4AHC A;  2R7Z A;  3K59 A;  1SMY D;  3M4A A;  3DU6 A;  1WCM A;  4Q5G A;  3K5L A;  3KYL A;  1DD5 A;  4Q5V A;  2A68 D;  1A35 A;  2JA6 A;  1TWG A;  3GTP A;  2E2I A;  4FXD A;  4JLR C; 
#chains in the Genus database with same CATH homology
 1RRJ A;  1WQF A;  4QIW A;  3MAQ A;  2O5J D;  5MLC 9;  3HKZ A;  1K83 A;  2JA7 A;  1SEU A;  2A6H D;  1I3Q A;  1IW7 D;  1R49 A;  1TWA A;  1YNJ D;  3GTM A;  3K5N A;  3K58 A;  3K57 A;  4KDD A;  3GTQ A;  1ISE A;  3WVO A;  3SJR A;  4EJ3 A;  4C2M A;  4OYD B;  2YU9 A;  1T8I A;  3K5O A;  1Q8I A;  1MIU A;  1SC7 A;  1EJ9 A;  3GTK A;  1WQH A;  3GTL A;  2R93 A;  1TL8 A;  2R4G A;  4FGU A;  5JSB B;  1K4T A;  1I50 A;  2WAQ A;  4F3E A;  4NOL A;  4AYB A;  1TWH A;  4KAW X;  1LPQ A;  4NOM A;  1SFO A;  2A69 D;  2B9S B;  3H0G A;  2NVY A;  4IP8 A;  1Y69 8;  1TGO A;  3P9A A;  4GFQ A;  1ZYR D;  2Y0S A;  2E2H A;  4D3Y A;  1YNN D;  1A31 A;  4LMO A;  1R9T A;  4D3Z A;  4KB2 A;  3DU5 A;  3LF9 A;  4O26 A;  3IAY A;  1TWC A;  2CW0 D;  1I6V D;  2WB1 A;  2F4Q A;  2A6E D;  3LHP S;  5C9H A;  5JSN B;  2BE5 D;  2NVX A;  1IS1 A;  4IP9 A;  3CQZ A;  1R5Z A;  1GE9 A;  1Y1W A;  1Y1V A;  3GTG A;  1HQM D;  1A36 A;  4AN8 A;  3GTO A;  4NOK A;  1K4S A;  1RR8 C;  2VUM A;  5CQG A;  1EH1 A;  4QCL A;  3FKI A;  1TWF A;  4H3T A;  2B63 A;  1V9M A;  1NH3 A;  1EK8 A;  3K5M A;  2JA5 A;  4FYD A;  1WQG A;  4KC6 A;  3GTJ A;  4KB4 A;  2PMZ A;  2R92 A;  4L8I A;  4AHC A;  2R7Z A;  3K59 A;  1SMY D;  3M4A A;  3DU6 A;  1WCM A;  4Q5G A;  3K5L A;  3KYL A;  1DD5 A;  4Q5V A;  2A68 D;  1A35 A;  2JA6 A;  1TWG A;  3GTP A;  2E2I A;  4FXD A;  4JLR C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...