4IP8A

Structure of human serum amyloid a1
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
105
structure length
105
Chain Sequence
MRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 47
structure length 105
sequence length 105
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip8A00
4IP8A 4Q5GA 4IP9A
chains in the Genus database with same CATH superfamily
4IP8A 1SFOA 1YNJD 1A35A 1K4TA 1TWGA 1IW7D 4NOLA 5JSBB 4F3EA 4FXDA 3GTOA 3GTPA 2WAQA 1V9MA 2A68D 4AN8A 4KAWX 3K5LA 1WCMA 3SJRA 1GE9A 4Q5GA 1R49A 4GFQA 4NOMA 1K83A 4H3TA 1I50A 3GTLA 1I3QA 2A69D 4D3ZA 4AHCA 2PMZA 3M4AA 5JSNB 1K4SA 1EJ9A 2JA6A 3DU6A 4KB4A 1A36A 2JA5A 1I6VD 2R7ZA 2E2IA 5CQGA 1SEUA 4IP9A 1R5ZA 3K59A 3K5NA 4AYBA 1TWFA 4KDDA 1LPQA 1EH1A 1SMYD 3WVOA 3LHPS 3KYLA 4KC6A 1A31A 1TWCA 1WQHA 4O26A 3GTKA 3CQZA 1HQMD 1WQFA 1RRJA 3H0GA 3MAQA 1Y1WA 1SC7A 5C9HA 3FKIA 4C2MA 1DD5A 3LF9A 5MLC9 4LMOA 1EK8A 1WQGA 1IS1A 3DU5A 4Q5VA 2VUMA 4D3YA 1TGOA 2A6HD 1NH3A 4FGUA 3P9AA 3GTGA 2A6ED 2B63A 4OYDB 1TWAA 3K5OA 1TL8A 4QIWA 4NOKA 3GTJA 1TWHA 4KB2A 1R9TA 2Y0SA 2R92A 4JLRC 2O5JD 2BE5D 2NVYA 3K57A 3GTMA 3HKZA 3IAYA 1Y1VA 1Y698 2R4GA 2NVXA 4L8IA 1T8IA 4EJ3A 1Q8IA 4QCLA 1YNND 4FYDA 1MIUA 3K5MA 2B9SB 1ZYRD 2R93A 2CW0D 2WB1A 2YU9A 1RR8C 3GTQA 2F4QA 2E2HA 1ISEA 3K58A 2JA7A
chains in the Genus database with same CATH topology
4IP8A 1SFOA 1YNJD 1A35A 1K4TA 1TWGA 1IW7D 4NOLA 5JSBB 4F3EA 4FXDA 3GTOA 3GTPA 2WAQA 1V9MA 2A68D 4AN8A 4KAWX 3K5LA 1WCMA 3SJRA 1GE9A 4Q5GA 1R49A 4GFQA 4NOMA 1K83A 4H3TA 1I50A 3GTLA 1I3QA 2A69D 4D3ZA 4AHCA 2PMZA 3M4AA 5JSNB 1K4SA 1EJ9A 2JA6A 3DU6A 4KB4A 1A36A 2JA5A 1I6VD 2R7ZA 2E2IA 5CQGA 1SEUA 4IP9A 1R5ZA 3K59A 3K5NA 4AYBA 1TWFA 4KDDA 1LPQA 1EH1A 1SMYD 3WVOA 3LHPS 3KYLA 4KC6A 1A31A 1TWCA 1WQHA 4O26A 3GTKA 3CQZA 1HQMD 1WQFA 1RRJA 3H0GA 3MAQA 1Y1WA 1SC7A 5C9HA 3FKIA 4C2MA 1DD5A 3LF9A 5MLC9 4LMOA 1EK8A 1WQGA 1IS1A 3DU5A 4Q5VA 2VUMA 4D3YA 1TGOA 2A6HD 1NH3A 4FGUA 3P9AA 3GTGA 2A6ED 2B63A 4OYDB 1TWAA 3K5OA 1TL8A 4QIWA 4NOKA 3GTJA 1TWHA 4KB2A 1R9TA 2Y0SA 2R92A 4JLRC 2O5JD 2BE5D 2NVYA 3K57A 3GTMA 3HKZA 3IAYA 1Y1VA 1Y698 2R4GA 2NVXA 4L8IA 1T8IA 4EJ3A 1Q8IA 4QCLA 1YNND 4FYDA 1MIUA 3K5MA 2B9SB 1ZYRD 2R93A 2CW0D 2WB1A 2YU9A 1RR8C 3GTQA 2F4QA 2E2HA 1ISEA 3K58A 2JA7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP8 A;  4Q5G A;  4IP9 A; 
#chains in the Genus database with same CATH topology
 4IP8 A;  1SFO A;  1YNJ D;  1A35 A;  1K4T A;  1TWG A;  1IW7 D;  4NOL A;  5JSB B;  4F3E A;  4FXD A;  3GTO A;  3GTP A;  2WAQ A;  1V9M A;  2A68 D;  4AN8 A;  4KAW X;  3K5L A;  1WCM A;  3SJR A;  1GE9 A;  4Q5G A;  1R49 A;  4GFQ A;  4NOM A;  1K83 A;  4H3T A;  1I50 A;  3GTL A;  1I3Q A;  2A69 D;  4D3Z A;  4AHC A;  2PMZ A;  3M4A A;  5JSN B;  1K4S A;  1EJ9 A;  2JA6 A;  3DU6 A;  4KB4 A;  1A36 A;  2JA5 A;  1I6V D;  2R7Z A;  2E2I A;  5CQG A;  1SEU A;  4IP9 A;  1R5Z A;  3K59 A;  3K5N A;  4AYB A;  1TWF A;  4KDD A;  1LPQ A;  1EH1 A;  1SMY D;  3WVO A;  3LHP S;  3KYL A;  4KC6 A;  1A31 A;  1TWC A;  1WQH A;  4O26 A;  3GTK A;  3CQZ A;  1HQM D;  1WQF A;  1RRJ A;  3H0G A;  3MAQ A;  1Y1W A;  1SC7 A;  5C9H A;  3FKI A;  4C2M A;  1DD5 A;  3LF9 A;  5MLC 9;  4LMO A;  1EK8 A;  1WQG A;  1IS1 A;  3DU5 A;  4Q5V A;  2VUM A;  4D3Y A;  1TGO A;  2A6H D;  1NH3 A;  4FGU A;  3P9A A;  3GTG A;  2A6E D;  2B63 A;  4OYD B;  1TWA A;  3K5O A;  1TL8 A;  4QIW A;  4NOK A;  3GTJ A;  1TWH A;  4KB2 A;  1R9T A;  2Y0S A;  2R92 A;  4JLR C;  2O5J D;  2BE5 D;  2NVY A;  3K57 A;  3GTM A;  3HKZ A;  3IAY A;  1Y1V A;  1Y69 8;  2R4G A;  2NVX A;  4L8I A;  1T8I A;  4EJ3 A;  1Q8I A;  4QCL A;  1YNN D;  4FYD A;  1MIU A;  3K5M A;  2B9S B;  1ZYR D;  2R93 A;  2CW0 D;  2WB1 A;  2YU9 A;  1RR8 C;  3GTQ A;  2F4Q A;  2E2H A;  1ISE A;  3K58 A;  2JA7 A; 
#chains in the Genus database with same CATH homology
 4IP8 A;  1SFO A;  1YNJ D;  1A35 A;  1K4T A;  1TWG A;  1IW7 D;  4NOL A;  5JSB B;  4F3E A;  4FXD A;  3GTO A;  3GTP A;  2WAQ A;  1V9M A;  2A68 D;  4AN8 A;  4KAW X;  3K5L A;  1WCM A;  3SJR A;  1GE9 A;  4Q5G A;  1R49 A;  4GFQ A;  4NOM A;  1K83 A;  4H3T A;  1I50 A;  3GTL A;  1I3Q A;  2A69 D;  4D3Z A;  4AHC A;  2PMZ A;  3M4A A;  5JSN B;  1K4S A;  1EJ9 A;  2JA6 A;  3DU6 A;  4KB4 A;  1A36 A;  2JA5 A;  1I6V D;  2R7Z A;  2E2I A;  5CQG A;  1SEU A;  4IP9 A;  1R5Z A;  3K59 A;  3K5N A;  4AYB A;  1TWF A;  4KDD A;  1LPQ A;  1EH1 A;  1SMY D;  3WVO A;  3LHP S;  3KYL A;  4KC6 A;  1A31 A;  1TWC A;  1WQH A;  4O26 A;  3GTK A;  3CQZ A;  1HQM D;  1WQF A;  1RRJ A;  3H0G A;  3MAQ A;  1Y1W A;  1SC7 A;  5C9H A;  3FKI A;  4C2M A;  1DD5 A;  3LF9 A;  5MLC 9;  4LMO A;  1EK8 A;  1WQG A;  1IS1 A;  3DU5 A;  4Q5V A;  2VUM A;  4D3Y A;  1TGO A;  2A6H D;  1NH3 A;  4FGU A;  3P9A A;  3GTG A;  2A6E D;  2B63 A;  4OYD B;  1TWA A;  3K5O A;  1TL8 A;  4QIW A;  4NOK A;  3GTJ A;  1TWH A;  4KB2 A;  1R9T A;  2Y0S A;  2R92 A;  4JLR C;  2O5J D;  2BE5 D;  2NVY A;  3K57 A;  3GTM A;  3HKZ A;  3IAY A;  1Y1V A;  1Y69 8;  2R4G A;  2NVX A;  4L8I A;  1T8I A;  4EJ3 A;  1Q8I A;  4QCL A;  1YNN D;  4FYD A;  1MIU A;  3K5M A;  2B9S B;  1ZYR D;  2R93 A;  2CW0 D;  2WB1 A;  2YU9 A;  1RR8 C;  3GTQ A;  2F4Q A;  2E2H A;  1ISE A;  3K58 A;  2JA7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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