4IP9A

Structure of native human serum amyloid a1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
104
structure length
104
Chain Sequence
RSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 41
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip9A00
4Q5GA 4IP9A 4IP8A
chains in the Genus database with same CATH superfamily
1A31A 4KC6A 1SEUA 4FXDA 3DU5A 4AHCA 2A68D 2R93A 2R92A 2R7ZA 1RRJA 4IP9A 4KB2A 5JSBB 1K4SA 3IAYA 2F4QA 4F3EA 1EJ9A 1TWAA 3K5LA 1Y1VA 4H3TA 1DD5A 1I3QA 1EK8A 3DU6A 1I50A 1WQGA 3SJRA 4Q5GA 2JA5A 3MAQA 2A6HD 3K5MA 3K58A 2Y0SA 4NOMA 3FKIA 4EJ3A 4KDDA 2JA6A 1NH3A 5C9HA 1ISEA 4Q5VA 1IW7D 1EH1A 3P9AA 4L8IA 2B9SB 1T8IA 3GTQA 2YU9A 1A35A 4AN8A 4FGUA 3CQZA 1WCMA 1I6VD 2O5JD 1Y698 3LHPS 1SFOA 1SC7A 2VUMA 4GFQA 4D3ZA 2NVXA 1Q8IA 4QIWA 5MLC9 3M4AA 2B63A 2BE5D 1TGOA 3K5OA 2A6ED 1IS1A 3GTLA 1WQHA 4O26A 4NOLA 3GTPA 2E2IA 2JA7A 1SMYD 2WB1A 4OYDB 1R49A 4D3YA 1TWGA 2PMZA 1MIUA 1LPQA 1TWCA 3GTMA 3GTOA 3K59A 1TWHA 1R9TA 1R5ZA 1HQMD 2WAQA 2CW0D 3WVOA 1TWFA 2A69D 2NVYA 3KYLA 1TL8A 1Y1WA 3GTGA 1WQFA 3K5NA 3HKZA 5JSNB 3H0GA 3K57A 4C2MA 2E2HA 3GTJA 1A36A 1V9MA 4LMOA 1GE9A 4KB4A 3GTKA 4JLRC 5CQGA 1K4TA 4IP8A 4NOKA 3LF9A 1YNJD 1YNND 4QCLA 2R4GA 1K83A 1ZYRD 1RR8C 4FYDA 4AYBA 4KAWX
chains in the Genus database with same CATH topology
1A31A 4KC6A 1SEUA 4FXDA 3DU5A 4AHCA 2A68D 2R93A 2R92A 2R7ZA 1RRJA 4IP9A 4KB2A 5JSBB 1K4SA 3IAYA 2F4QA 4F3EA 1EJ9A 1TWAA 3K5LA 1Y1VA 4H3TA 1DD5A 1I3QA 1EK8A 3DU6A 1I50A 1WQGA 3SJRA 4Q5GA 2JA5A 3MAQA 2A6HD 3K5MA 3K58A 2Y0SA 4NOMA 3FKIA 4EJ3A 4KDDA 2JA6A 1NH3A 5C9HA 1ISEA 4Q5VA 1IW7D 1EH1A 3P9AA 4L8IA 2B9SB 1T8IA 3GTQA 2YU9A 1A35A 4AN8A 4FGUA 3CQZA 1WCMA 1I6VD 2O5JD 1Y698 3LHPS 1SFOA 1SC7A 2VUMA 4GFQA 4D3ZA 2NVXA 1Q8IA 4QIWA 5MLC9 3M4AA 2B63A 2BE5D 1TGOA 3K5OA 2A6ED 1IS1A 3GTLA 1WQHA 4O26A 4NOLA 3GTPA 2E2IA 2JA7A 1SMYD 2WB1A 4OYDB 1R49A 4D3YA 1TWGA 2PMZA 1MIUA 1LPQA 1TWCA 3GTMA 3GTOA 3K59A 1TWHA 1R9TA 1R5ZA 1HQMD 2WAQA 2CW0D 3WVOA 1TWFA 2A69D 2NVYA 3KYLA 1TL8A 1Y1WA 3GTGA 1WQFA 3K5NA 3HKZA 5JSNB 3H0GA 3K57A 4C2MA 2E2HA 3GTJA 1A36A 1V9MA 4LMOA 1GE9A 4KB4A 3GTKA 4JLRC 5CQGA 1K4TA 4IP8A 4NOKA 3LF9A 1YNJD 1YNND 4QCLA 2R4GA 1K83A 1ZYRD 1RR8C 4FYDA 4AYBA 4KAWX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q5G A;  4IP9 A;  4IP8 A; 
#chains in the Genus database with same CATH topology
 1A31 A;  4KC6 A;  1SEU A;  4FXD A;  3DU5 A;  4AHC A;  2A68 D;  2R93 A;  2R92 A;  2R7Z A;  1RRJ A;  4IP9 A;  4KB2 A;  5JSB B;  1K4S A;  3IAY A;  2F4Q A;  4F3E A;  1EJ9 A;  1TWA A;  3K5L A;  1Y1V A;  4H3T A;  1DD5 A;  1I3Q A;  1EK8 A;  3DU6 A;  1I50 A;  1WQG A;  3SJR A;  4Q5G A;  2JA5 A;  3MAQ A;  2A6H D;  3K5M A;  3K58 A;  2Y0S A;  4NOM A;  3FKI A;  4EJ3 A;  4KDD A;  2JA6 A;  1NH3 A;  5C9H A;  1ISE A;  4Q5V A;  1IW7 D;  1EH1 A;  3P9A A;  4L8I A;  2B9S B;  1T8I A;  3GTQ A;  2YU9 A;  1A35 A;  4AN8 A;  4FGU A;  3CQZ A;  1WCM A;  1I6V D;  2O5J D;  1Y69 8;  3LHP S;  1SFO A;  1SC7 A;  2VUM A;  4GFQ A;  4D3Z A;  2NVX A;  1Q8I A;  4QIW A;  5MLC 9;  3M4A A;  2B63 A;  2BE5 D;  1TGO A;  3K5O A;  2A6E D;  1IS1 A;  3GTL A;  1WQH A;  4O26 A;  4NOL A;  3GTP A;  2E2I A;  2JA7 A;  1SMY D;  2WB1 A;  4OYD B;  1R49 A;  4D3Y A;  1TWG A;  2PMZ A;  1MIU A;  1LPQ A;  1TWC A;  3GTM A;  3GTO A;  3K59 A;  1TWH A;  1R9T A;  1R5Z A;  1HQM D;  2WAQ A;  2CW0 D;  3WVO A;  1TWF A;  2A69 D;  2NVY A;  3KYL A;  1TL8 A;  1Y1W A;  3GTG A;  1WQF A;  3K5N A;  3HKZ A;  5JSN B;  3H0G A;  3K57 A;  4C2M A;  2E2H A;  3GTJ A;  1A36 A;  1V9M A;  4LMO A;  1GE9 A;  4KB4 A;  3GTK A;  4JLR C;  5CQG A;  1K4T A;  4IP8 A;  4NOK A;  3LF9 A;  1YNJ D;  1YNN D;  4QCL A;  2R4G A;  1K83 A;  1ZYR D;  1RR8 C;  4FYD A;  4AYB A;  4KAW X; 
#chains in the Genus database with same CATH homology
 1A31 A;  4KC6 A;  1SEU A;  4FXD A;  3DU5 A;  4AHC A;  2A68 D;  2R93 A;  2R92 A;  2R7Z A;  1RRJ A;  4IP9 A;  4KB2 A;  5JSB B;  1K4S A;  3IAY A;  2F4Q A;  4F3E A;  1EJ9 A;  1TWA A;  3K5L A;  1Y1V A;  4H3T A;  1DD5 A;  1I3Q A;  1EK8 A;  3DU6 A;  1I50 A;  1WQG A;  3SJR A;  4Q5G A;  2JA5 A;  3MAQ A;  2A6H D;  3K5M A;  3K58 A;  2Y0S A;  4NOM A;  3FKI A;  4EJ3 A;  4KDD A;  2JA6 A;  1NH3 A;  5C9H A;  1ISE A;  4Q5V A;  1IW7 D;  1EH1 A;  3P9A A;  4L8I A;  2B9S B;  1T8I A;  3GTQ A;  2YU9 A;  1A35 A;  4AN8 A;  4FGU A;  3CQZ A;  1WCM A;  1I6V D;  2O5J D;  1Y69 8;  3LHP S;  1SFO A;  1SC7 A;  2VUM A;  4GFQ A;  4D3Z A;  2NVX A;  1Q8I A;  4QIW A;  5MLC 9;  3M4A A;  2B63 A;  2BE5 D;  1TGO A;  3K5O A;  2A6E D;  1IS1 A;  3GTL A;  1WQH A;  4O26 A;  4NOL A;  3GTP A;  2E2I A;  2JA7 A;  1SMY D;  2WB1 A;  4OYD B;  1R49 A;  4D3Y A;  1TWG A;  2PMZ A;  1MIU A;  1LPQ A;  1TWC A;  3GTM A;  3GTO A;  3K59 A;  1TWH A;  1R9T A;  1R5Z A;  1HQM D;  2WAQ A;  2CW0 D;  3WVO A;  1TWF A;  2A69 D;  2NVY A;  3KYL A;  1TL8 A;  1Y1W A;  3GTG A;  1WQF A;  3K5N A;  3HKZ A;  5JSN B;  3H0G A;  3K57 A;  4C2M A;  2E2H A;  3GTJ A;  1A36 A;  1V9M A;  4LMO A;  1GE9 A;  4KB4 A;  3GTK A;  4JLR C;  5CQG A;  1K4T A;  4IP8 A;  4NOK A;  3LF9 A;  1YNJ D;  1YNN D;  4QCL A;  2R4G A;  1K83 A;  1ZYR D;  1RR8 C;  4FYD A;  4AYB A;  4KAW X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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