4IP9A

Structure of native human serum amyloid a1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
104
structure length
104
Chain Sequence
RSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule keywords Serum amyloid A-1 protein
total genus 41
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip9A00
4IP8A 4Q5GA 4IP9A
chains in the Genus database with same CATH superfamily
3K5OA 2R7ZA 4Q5VA 2F4QA 1I6VD 1YNJD 1GE9A 3K57A 4GFQA 1K4SA 3GTGA 4OYDB 2B9SB 1SFOA 1Y698 2WAQA 1WQGA 4KAWX 4H3TA 1MIUA 3GTQA 1TWCA 5CQGA 4LMOA 4FGUA 3WVOA 1T8IA 3GTKA 3K59A 3GTJA 1A36A 2A69D 2CW0D 4L8IA 3CQZA 1TGOA 1TWFA 1HQMD 3H0GA 4KB4A 3P9AA 1IW7D 2WB1A 1R5ZA 1I50A 1TL8A 2A6ED 2E2IA 1ZYRD 3IAYA 1SC7A 1YNND 2NVYA 4O26A 4IP8A 1A35A 3K5LA 2A6HD 3K5NA 1V9MA 2R93A 2YU9A 1EH1A 5C9HA 2O5JD 3K58A 4FYDA 1DD5A 1RR8C 4C2MA 2PMZA 2A68D 4KC6A 3MAQA 3LHPS 1Y1WA 4AHCA 4D3YA 1TWGA 1R9TA 2JA7A 4EJ3A 3DU6A 3LF9A 4AN8A 2R4GA 5JSBB 1EK8A 2BE5D 5JSNB 4KB2A 2VUMA 4NOKA 1IS1A 1SEUA 1TWHA 1K83A 4AYBA 3GTMA 3M4AA 1R49A 1TWAA 3KYLA 2Y0SA 4NOMA 3HKZA 4Q5GA 3GTLA 4IP9A 2NVXA 4FXDA 4QCLA 1Q8IA 1NH3A 3GTPA 2B63A 2JA5A 3FKIA 1WQFA 4D3ZA 3K5MA 2R92A 1ISEA 4F3EA 1WCMA 2E2HA 1RRJA 1A31A 3GTOA 1WQHA 1I3QA 1EJ9A 4KDDA 4JLRC 1SMYD 4QIWA 2JA6A 3SJRA 1K4TA 4NOLA 5MLC9 1Y1VA 3DU5A 1LPQA
chains in the Genus database with same CATH topology
3K5OA 2R7ZA 4Q5VA 2F4QA 1I6VD 1YNJD 1GE9A 3K57A 4GFQA 1K4SA 3GTGA 4OYDB 2B9SB 1SFOA 1Y698 2WAQA 1WQGA 4KAWX 4H3TA 1MIUA 3GTQA 1TWCA 5CQGA 4LMOA 4FGUA 3WVOA 1T8IA 3GTKA 3K59A 3GTJA 1A36A 2A69D 2CW0D 4L8IA 3CQZA 1TGOA 1TWFA 1HQMD 3H0GA 4KB4A 3P9AA 1IW7D 2WB1A 1R5ZA 1I50A 1TL8A 2A6ED 2E2IA 1ZYRD 3IAYA 1SC7A 1YNND 2NVYA 4O26A 4IP8A 1A35A 3K5LA 2A6HD 3K5NA 1V9MA 2R93A 2YU9A 1EH1A 5C9HA 2O5JD 3K58A 4FYDA 1DD5A 1RR8C 4C2MA 2PMZA 2A68D 4KC6A 3MAQA 3LHPS 1Y1WA 4AHCA 4D3YA 1TWGA 1R9TA 2JA7A 4EJ3A 3DU6A 3LF9A 4AN8A 2R4GA 5JSBB 1EK8A 2BE5D 5JSNB 4KB2A 2VUMA 4NOKA 1IS1A 1SEUA 1TWHA 1K83A 4AYBA 3GTMA 3M4AA 1R49A 1TWAA 3KYLA 2Y0SA 4NOMA 3HKZA 4Q5GA 3GTLA 4IP9A 2NVXA 4FXDA 4QCLA 1Q8IA 1NH3A 3GTPA 2B63A 2JA5A 3FKIA 1WQFA 4D3ZA 3K5MA 2R92A 1ISEA 4F3EA 1WCMA 2E2HA 1RRJA 1A31A 3GTOA 1WQHA 1I3QA 1EJ9A 4KDDA 4JLRC 1SMYD 4QIWA 2JA6A 3SJRA 1K4TA 4NOLA 5MLC9 1Y1VA 3DU5A 1LPQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP8 A;  4Q5G A;  4IP9 A; 
#chains in the Genus database with same CATH topology
 3K5O A;  2R7Z A;  4Q5V A;  2F4Q A;  1I6V D;  1YNJ D;  1GE9 A;  3K57 A;  4GFQ A;  1K4S A;  3GTG A;  4OYD B;  2B9S B;  1SFO A;  1Y69 8;  2WAQ A;  1WQG A;  4KAW X;  4H3T A;  1MIU A;  3GTQ A;  1TWC A;  5CQG A;  4LMO A;  4FGU A;  3WVO A;  1T8I A;  3GTK A;  3K59 A;  3GTJ A;  1A36 A;  2A69 D;  2CW0 D;  4L8I A;  3CQZ A;  1TGO A;  1TWF A;  1HQM D;  3H0G A;  4KB4 A;  3P9A A;  1IW7 D;  2WB1 A;  1R5Z A;  1I50 A;  1TL8 A;  2A6E D;  2E2I A;  1ZYR D;  3IAY A;  1SC7 A;  1YNN D;  2NVY A;  4O26 A;  4IP8 A;  1A35 A;  3K5L A;  2A6H D;  3K5N A;  1V9M A;  2R93 A;  2YU9 A;  1EH1 A;  5C9H A;  2O5J D;  3K58 A;  4FYD A;  1DD5 A;  1RR8 C;  4C2M A;  2PMZ A;  2A68 D;  4KC6 A;  3MAQ A;  3LHP S;  1Y1W A;  4AHC A;  4D3Y A;  1TWG A;  1R9T A;  2JA7 A;  4EJ3 A;  3DU6 A;  3LF9 A;  4AN8 A;  2R4G A;  5JSB B;  1EK8 A;  2BE5 D;  5JSN B;  4KB2 A;  2VUM A;  4NOK A;  1IS1 A;  1SEU A;  1TWH A;  1K83 A;  4AYB A;  3GTM A;  3M4A A;  1R49 A;  1TWA A;  3KYL A;  2Y0S A;  4NOM A;  3HKZ A;  4Q5G A;  3GTL A;  4IP9 A;  2NVX A;  4FXD A;  4QCL A;  1Q8I A;  1NH3 A;  3GTP A;  2B63 A;  2JA5 A;  3FKI A;  1WQF A;  4D3Z A;  3K5M A;  2R92 A;  1ISE A;  4F3E A;  1WCM A;  2E2H A;  1RRJ A;  1A31 A;  3GTO A;  1WQH A;  1I3Q A;  1EJ9 A;  4KDD A;  4JLR C;  1SMY D;  4QIW A;  2JA6 A;  3SJR A;  1K4T A;  4NOL A;  5MLC 9;  1Y1V A;  3DU5 A;  1LPQ A; 
#chains in the Genus database with same CATH homology
 3K5O A;  2R7Z A;  4Q5V A;  2F4Q A;  1I6V D;  1YNJ D;  1GE9 A;  3K57 A;  4GFQ A;  1K4S A;  3GTG A;  4OYD B;  2B9S B;  1SFO A;  1Y69 8;  2WAQ A;  1WQG A;  4KAW X;  4H3T A;  1MIU A;  3GTQ A;  1TWC A;  5CQG A;  4LMO A;  4FGU A;  3WVO A;  1T8I A;  3GTK A;  3K59 A;  3GTJ A;  1A36 A;  2A69 D;  2CW0 D;  4L8I A;  3CQZ A;  1TGO A;  1TWF A;  1HQM D;  3H0G A;  4KB4 A;  3P9A A;  1IW7 D;  2WB1 A;  1R5Z A;  1I50 A;  1TL8 A;  2A6E D;  2E2I A;  1ZYR D;  3IAY A;  1SC7 A;  1YNN D;  2NVY A;  4O26 A;  4IP8 A;  1A35 A;  3K5L A;  2A6H D;  3K5N A;  1V9M A;  2R93 A;  2YU9 A;  1EH1 A;  5C9H A;  2O5J D;  3K58 A;  4FYD A;  1DD5 A;  1RR8 C;  4C2M A;  2PMZ A;  2A68 D;  4KC6 A;  3MAQ A;  3LHP S;  1Y1W A;  4AHC A;  4D3Y A;  1TWG A;  1R9T A;  2JA7 A;  4EJ3 A;  3DU6 A;  3LF9 A;  4AN8 A;  2R4G A;  5JSB B;  1EK8 A;  2BE5 D;  5JSN B;  4KB2 A;  2VUM A;  4NOK A;  1IS1 A;  1SEU A;  1TWH A;  1K83 A;  4AYB A;  3GTM A;  3M4A A;  1R49 A;  1TWA A;  3KYL A;  2Y0S A;  4NOM A;  3HKZ A;  4Q5G A;  3GTL A;  4IP9 A;  2NVX A;  4FXD A;  4QCL A;  1Q8I A;  1NH3 A;  3GTP A;  2B63 A;  2JA5 A;  3FKI A;  1WQF A;  4D3Z A;  3K5M A;  2R92 A;  1ISE A;  4F3E A;  1WCM A;  2E2H A;  1RRJ A;  1A31 A;  3GTO A;  1WQH A;  1I3Q A;  1EJ9 A;  4KDD A;  4JLR C;  1SMY D;  4QIW A;  2JA6 A;  3SJR A;  1K4T A;  4NOL A;  5MLC 9;  1Y1V A;  3DU5 A;  1LPQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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