4IP9A

Structure of native human serum amyloid a1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
104
structure length
104
Chain Sequence
RSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 41
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip9A00
4IP8A 4IP9A 4Q5GA
chains in the Genus database with same CATH superfamily
1A31A 1TWFA 2CW0D 3K5NA 1YNND 1GE9A 2A6HD 1A36A 3HKZA 2A6ED 2VUMA 1ZYRD 4AHCA 1K4SA 1SEUA 1RRJA 3KYLA 1TWGA 2PMZA 3SJRA 1RR8C 1TWHA 5JSNB 2B9SB 4KC6A 4LMOA 3FKIA 3K5OA 3GTKA 1WQFA 1SMYD 2WB1A 1SC7A 3GTJA 3GTQA 3K5LA 1DD5A 4H3TA 1IW7D 1WCMA 4F3EA 2A68D 4OYDB 4KB4A 2NVXA 2R7ZA 1EH1A 5MLC9 1I3QA 3H0GA 3LF9A 4IP8A 4KDDA 3P9AA 2WAQA 1WQGA 1Y698 3GTMA 2JA5A 4Q5GA 4KAWX 1TL8A 1T8IA 4QCLA 1EJ9A 4D3ZA 1Q8IA 1NH3A 4O26A 4AYBA 3GTLA 1SFOA 4FXDA 1TWAA 4FGUA 1V9MA 4L8IA 3MAQA 3DU6A 1R9TA 1ISEA 3CQZA 4NOLA 2E2HA 3GTGA 4AN8A 3LHPS 2JA7A 1IS1A 3GTOA 1K83A 4Q5VA 4IP9A 3GTPA 1TGOA 2B63A 4JLRC 1Y1VA 1I50A 4KB2A 2F4QA 1A35A 4NOKA 2JA6A 2E2IA 2NVYA 3K57A 4FYDA 1TWCA 2R92A 1I6VD 1HQMD 1YNJD 1EK8A 1R5ZA 1WQHA 4D3YA 2A69D 4NOMA 3K5MA 3K58A 1Y1WA 4EJ3A 3WVOA 2R4GA 3DU5A 5CQGA 5JSBB 2O5JD 2YU9A 5C9HA 1MIUA 3IAYA 3K59A 4QIWA 2R93A 4GFQA 2BE5D 3M4AA 1K4TA 1LPQA 1R49A 2Y0SA 4C2MA
chains in the Genus database with same CATH topology
1A31A 1TWFA 2CW0D 3K5NA 1YNND 1GE9A 2A6HD 1A36A 3HKZA 2A6ED 2VUMA 1ZYRD 4AHCA 1K4SA 1SEUA 1RRJA 3KYLA 1TWGA 2PMZA 3SJRA 1RR8C 1TWHA 5JSNB 2B9SB 4KC6A 4LMOA 3FKIA 3K5OA 3GTKA 1WQFA 1SMYD 2WB1A 1SC7A 3GTJA 3GTQA 3K5LA 1DD5A 4H3TA 1IW7D 1WCMA 4F3EA 2A68D 4OYDB 4KB4A 2NVXA 2R7ZA 1EH1A 5MLC9 1I3QA 3H0GA 3LF9A 4IP8A 4KDDA 3P9AA 2WAQA 1WQGA 1Y698 3GTMA 2JA5A 4Q5GA 4KAWX 1TL8A 1T8IA 4QCLA 1EJ9A 4D3ZA 1Q8IA 1NH3A 4O26A 4AYBA 3GTLA 1SFOA 4FXDA 1TWAA 4FGUA 1V9MA 4L8IA 3MAQA 3DU6A 1R9TA 1ISEA 3CQZA 4NOLA 2E2HA 3GTGA 4AN8A 3LHPS 2JA7A 1IS1A 3GTOA 1K83A 4Q5VA 4IP9A 3GTPA 1TGOA 2B63A 4JLRC 1Y1VA 1I50A 4KB2A 2F4QA 1A35A 4NOKA 2JA6A 2E2IA 2NVYA 3K57A 4FYDA 1TWCA 2R92A 1I6VD 1HQMD 1YNJD 1EK8A 1R5ZA 1WQHA 4D3YA 2A69D 4NOMA 3K5MA 3K58A 1Y1WA 4EJ3A 3WVOA 2R4GA 3DU5A 5CQGA 5JSBB 2O5JD 2YU9A 5C9HA 1MIUA 3IAYA 3K59A 4QIWA 2R93A 4GFQA 2BE5D 3M4AA 1K4TA 1LPQA 1R49A 2Y0SA 4C2MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP8 A;  4IP9 A;  4Q5G A; 
#chains in the Genus database with same CATH topology
 1A31 A;  1TWF A;  2CW0 D;  3K5N A;  1YNN D;  1GE9 A;  2A6H D;  1A36 A;  3HKZ A;  2A6E D;  2VUM A;  1ZYR D;  4AHC A;  1K4S A;  1SEU A;  1RRJ A;  3KYL A;  1TWG A;  2PMZ A;  3SJR A;  1RR8 C;  1TWH A;  5JSN B;  2B9S B;  4KC6 A;  4LMO A;  3FKI A;  3K5O A;  3GTK A;  1WQF A;  1SMY D;  2WB1 A;  1SC7 A;  3GTJ A;  3GTQ A;  3K5L A;  1DD5 A;  4H3T A;  1IW7 D;  1WCM A;  4F3E A;  2A68 D;  4OYD B;  4KB4 A;  2NVX A;  2R7Z A;  1EH1 A;  5MLC 9;  1I3Q A;  3H0G A;  3LF9 A;  4IP8 A;  4KDD A;  3P9A A;  2WAQ A;  1WQG A;  1Y69 8;  3GTM A;  2JA5 A;  4Q5G A;  4KAW X;  1TL8 A;  1T8I A;  4QCL A;  1EJ9 A;  4D3Z A;  1Q8I A;  1NH3 A;  4O26 A;  4AYB A;  3GTL A;  1SFO A;  4FXD A;  1TWA A;  4FGU A;  1V9M A;  4L8I A;  3MAQ A;  3DU6 A;  1R9T A;  1ISE A;  3CQZ A;  4NOL A;  2E2H A;  3GTG A;  4AN8 A;  3LHP S;  2JA7 A;  1IS1 A;  3GTO A;  1K83 A;  4Q5V A;  4IP9 A;  3GTP A;  1TGO A;  2B63 A;  4JLR C;  1Y1V A;  1I50 A;  4KB2 A;  2F4Q A;  1A35 A;  4NOK A;  2JA6 A;  2E2I A;  2NVY A;  3K57 A;  4FYD A;  1TWC A;  2R92 A;  1I6V D;  1HQM D;  1YNJ D;  1EK8 A;  1R5Z A;  1WQH A;  4D3Y A;  2A69 D;  4NOM A;  3K5M A;  3K58 A;  1Y1W A;  4EJ3 A;  3WVO A;  2R4G A;  3DU5 A;  5CQG A;  5JSB B;  2O5J D;  2YU9 A;  5C9H A;  1MIU A;  3IAY A;  3K59 A;  4QIW A;  2R93 A;  4GFQ A;  2BE5 D;  3M4A A;  1K4T A;  1LPQ A;  1R49 A;  2Y0S A;  4C2M A; 
#chains in the Genus database with same CATH homology
 1A31 A;  1TWF A;  2CW0 D;  3K5N A;  1YNN D;  1GE9 A;  2A6H D;  1A36 A;  3HKZ A;  2A6E D;  2VUM A;  1ZYR D;  4AHC A;  1K4S A;  1SEU A;  1RRJ A;  3KYL A;  1TWG A;  2PMZ A;  3SJR A;  1RR8 C;  1TWH A;  5JSN B;  2B9S B;  4KC6 A;  4LMO A;  3FKI A;  3K5O A;  3GTK A;  1WQF A;  1SMY D;  2WB1 A;  1SC7 A;  3GTJ A;  3GTQ A;  3K5L A;  1DD5 A;  4H3T A;  1IW7 D;  1WCM A;  4F3E A;  2A68 D;  4OYD B;  4KB4 A;  2NVX A;  2R7Z A;  1EH1 A;  5MLC 9;  1I3Q A;  3H0G A;  3LF9 A;  4IP8 A;  4KDD A;  3P9A A;  2WAQ A;  1WQG A;  1Y69 8;  3GTM A;  2JA5 A;  4Q5G A;  4KAW X;  1TL8 A;  1T8I A;  4QCL A;  1EJ9 A;  4D3Z A;  1Q8I A;  1NH3 A;  4O26 A;  4AYB A;  3GTL A;  1SFO A;  4FXD A;  1TWA A;  4FGU A;  1V9M A;  4L8I A;  3MAQ A;  3DU6 A;  1R9T A;  1ISE A;  3CQZ A;  4NOL A;  2E2H A;  3GTG A;  4AN8 A;  3LHP S;  2JA7 A;  1IS1 A;  3GTO A;  1K83 A;  4Q5V A;  4IP9 A;  3GTP A;  1TGO A;  2B63 A;  4JLR C;  1Y1V A;  1I50 A;  4KB2 A;  2F4Q A;  1A35 A;  4NOK A;  2JA6 A;  2E2I A;  2NVY A;  3K57 A;  4FYD A;  1TWC A;  2R92 A;  1I6V D;  1HQM D;  1YNJ D;  1EK8 A;  1R5Z A;  1WQH A;  4D3Y A;  2A69 D;  4NOM A;  3K5M A;  3K58 A;  1Y1W A;  4EJ3 A;  3WVO A;  2R4G A;  3DU5 A;  5CQG A;  5JSB B;  2O5J D;  2YU9 A;  5C9H A;  1MIU A;  3IAY A;  3K59 A;  4QIW A;  2R93 A;  4GFQ A;  2BE5 D;  3M4A A;  1K4T A;  1LPQ A;  1R49 A;  2Y0S A;  4C2M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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