4IP9A

Structure of native human serum amyloid a1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
104
structure length
104
Chain Sequence
RSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule keywords Serum amyloid A-1 protein
total genus 41
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip9A00
4IP8A 4Q5GA 4IP9A
chains in the Genus database with same CATH superfamily
3KYLA 1TWAA 1WQGA 3K5MA 4IP8A 1K4TA 1MIUA 1SMYD 2CW0D 1DD5A 4D3YA 1R5ZA 1HQMD 4OYDB 1V9MA 3K57A 3DU6A 3M4AA 2R7ZA 3P9AA 1Q8IA 4EJ3A 1A36A 1K4SA 1I6VD 1R49A 3K5LA 2A6HD 3MAQA 4NOMA 3WVOA 4KB2A 4KAWX 1EH1A 3GTLA 2PMZA 1SFOA 4FYDA 1Y698 2WAQA 3HKZA 3DU5A 2JA6A 2BE5D 2B63A 2WB1A 2F4QA 1EJ9A 1T8IA 1RRJA 4FGUA 1Y1VA 1TWCA 1TWGA 4D3ZA 1SC7A 3K5OA 3K59A 3GTPA 1ISEA 1WQFA 2JA7A 1K83A 2NVYA 2JA5A 5MLC9 3GTMA 4AN8A 1IS1A 4O26A 2R93A 2O5JD 1YNND 5JSNB 4KC6A 1RR8C 2NVXA 1TWHA 3K5NA 3GTQA 4IP9A 2R92A 1I50A 1IW7D 4H3TA 3SJRA 4JLRC 1TGOA 1ZYRD 3K58A 1WCMA 1GE9A 3LHPS 4Q5GA 2A68D 1LPQA 2R4GA 5JSBB 1I3QA 4C2MA 4FXDA 3GTJA 1NH3A 3GTOA 2E2HA 3H0GA 1WQHA 1YNJD 2VUMA 4L8IA 2Y0SA 3FKIA 3LF9A 1TWFA 4KB4A 4NOLA 4F3EA 4AHCA 3IAYA 4AYBA 2YU9A 4GFQA 3CQZA 3GTKA 2B9SB 2A69D 4QIWA 1Y1WA 2E2IA 4QCLA 4KDDA 5C9HA 3GTGA 1A31A 5CQGA 1TL8A 1EK8A 4NOKA 1R9TA 4LMOA 1A35A 2A6ED 1SEUA 4Q5VA
chains in the Genus database with same CATH topology
3KYLA 1TWAA 1WQGA 3K5MA 4IP8A 1K4TA 1MIUA 1SMYD 2CW0D 1DD5A 4D3YA 1R5ZA 1HQMD 4OYDB 1V9MA 3K57A 3DU6A 3M4AA 2R7ZA 3P9AA 1Q8IA 4EJ3A 1A36A 1K4SA 1I6VD 1R49A 3K5LA 2A6HD 3MAQA 4NOMA 3WVOA 4KB2A 4KAWX 1EH1A 3GTLA 2PMZA 1SFOA 4FYDA 1Y698 2WAQA 3HKZA 3DU5A 2JA6A 2BE5D 2B63A 2WB1A 2F4QA 1EJ9A 1T8IA 1RRJA 4FGUA 1Y1VA 1TWCA 1TWGA 4D3ZA 1SC7A 3K5OA 3K59A 3GTPA 1ISEA 1WQFA 2JA7A 1K83A 2NVYA 2JA5A 5MLC9 3GTMA 4AN8A 1IS1A 4O26A 2R93A 2O5JD 1YNND 5JSNB 4KC6A 1RR8C 2NVXA 1TWHA 3K5NA 3GTQA 4IP9A 2R92A 1I50A 1IW7D 4H3TA 3SJRA 4JLRC 1TGOA 1ZYRD 3K58A 1WCMA 1GE9A 3LHPS 4Q5GA 2A68D 1LPQA 2R4GA 5JSBB 1I3QA 4C2MA 4FXDA 3GTJA 1NH3A 3GTOA 2E2HA 3H0GA 1WQHA 1YNJD 2VUMA 4L8IA 2Y0SA 3FKIA 3LF9A 1TWFA 4KB4A 4NOLA 4F3EA 4AHCA 3IAYA 4AYBA 2YU9A 4GFQA 3CQZA 3GTKA 2B9SB 2A69D 4QIWA 1Y1WA 2E2IA 4QCLA 4KDDA 5C9HA 3GTGA 1A31A 5CQGA 1TL8A 1EK8A 4NOKA 1R9TA 4LMOA 1A35A 2A6ED 1SEUA 4Q5VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP8 A;  4Q5G A;  4IP9 A; 
#chains in the Genus database with same CATH topology
 3KYL A;  1TWA A;  1WQG A;  3K5M A;  4IP8 A;  1K4T A;  1MIU A;  1SMY D;  2CW0 D;  1DD5 A;  4D3Y A;  1R5Z A;  1HQM D;  4OYD B;  1V9M A;  3K57 A;  3DU6 A;  3M4A A;  2R7Z A;  3P9A A;  1Q8I A;  4EJ3 A;  1A36 A;  1K4S A;  1I6V D;  1R49 A;  3K5L A;  2A6H D;  3MAQ A;  4NOM A;  3WVO A;  4KB2 A;  4KAW X;  1EH1 A;  3GTL A;  2PMZ A;  1SFO A;  4FYD A;  1Y69 8;  2WAQ A;  3HKZ A;  3DU5 A;  2JA6 A;  2BE5 D;  2B63 A;  2WB1 A;  2F4Q A;  1EJ9 A;  1T8I A;  1RRJ A;  4FGU A;  1Y1V A;  1TWC A;  1TWG A;  4D3Z A;  1SC7 A;  3K5O A;  3K59 A;  3GTP A;  1ISE A;  1WQF A;  2JA7 A;  1K83 A;  2NVY A;  2JA5 A;  5MLC 9;  3GTM A;  4AN8 A;  1IS1 A;  4O26 A;  2R93 A;  2O5J D;  1YNN D;  5JSN B;  4KC6 A;  1RR8 C;  2NVX A;  1TWH A;  3K5N A;  3GTQ A;  4IP9 A;  2R92 A;  1I50 A;  1IW7 D;  4H3T A;  3SJR A;  4JLR C;  1TGO A;  1ZYR D;  3K58 A;  1WCM A;  1GE9 A;  3LHP S;  4Q5G A;  2A68 D;  1LPQ A;  2R4G A;  5JSB B;  1I3Q A;  4C2M A;  4FXD A;  3GTJ A;  1NH3 A;  3GTO A;  2E2H A;  3H0G A;  1WQH A;  1YNJ D;  2VUM A;  4L8I A;  2Y0S A;  3FKI A;  3LF9 A;  1TWF A;  4KB4 A;  4NOL A;  4F3E A;  4AHC A;  3IAY A;  4AYB A;  2YU9 A;  4GFQ A;  3CQZ A;  3GTK A;  2B9S B;  2A69 D;  4QIW A;  1Y1W A;  2E2I A;  4QCL A;  4KDD A;  5C9H A;  3GTG A;  1A31 A;  5CQG A;  1TL8 A;  1EK8 A;  4NOK A;  1R9T A;  4LMO A;  1A35 A;  2A6E D;  1SEU A;  4Q5V A; 
#chains in the Genus database with same CATH homology
 3KYL A;  1TWA A;  1WQG A;  3K5M A;  4IP8 A;  1K4T A;  1MIU A;  1SMY D;  2CW0 D;  1DD5 A;  4D3Y A;  1R5Z A;  1HQM D;  4OYD B;  1V9M A;  3K57 A;  3DU6 A;  3M4A A;  2R7Z A;  3P9A A;  1Q8I A;  4EJ3 A;  1A36 A;  1K4S A;  1I6V D;  1R49 A;  3K5L A;  2A6H D;  3MAQ A;  4NOM A;  3WVO A;  4KB2 A;  4KAW X;  1EH1 A;  3GTL A;  2PMZ A;  1SFO A;  4FYD A;  1Y69 8;  2WAQ A;  3HKZ A;  3DU5 A;  2JA6 A;  2BE5 D;  2B63 A;  2WB1 A;  2F4Q A;  1EJ9 A;  1T8I A;  1RRJ A;  4FGU A;  1Y1V A;  1TWC A;  1TWG A;  4D3Z A;  1SC7 A;  3K5O A;  3K59 A;  3GTP A;  1ISE A;  1WQF A;  2JA7 A;  1K83 A;  2NVY A;  2JA5 A;  5MLC 9;  3GTM A;  4AN8 A;  1IS1 A;  4O26 A;  2R93 A;  2O5J D;  1YNN D;  5JSN B;  4KC6 A;  1RR8 C;  2NVX A;  1TWH A;  3K5N A;  3GTQ A;  4IP9 A;  2R92 A;  1I50 A;  1IW7 D;  4H3T A;  3SJR A;  4JLR C;  1TGO A;  1ZYR D;  3K58 A;  1WCM A;  1GE9 A;  3LHP S;  4Q5G A;  2A68 D;  1LPQ A;  2R4G A;  5JSB B;  1I3Q A;  4C2M A;  4FXD A;  3GTJ A;  1NH3 A;  3GTO A;  2E2H A;  3H0G A;  1WQH A;  1YNJ D;  2VUM A;  4L8I A;  2Y0S A;  3FKI A;  3LF9 A;  1TWF A;  4KB4 A;  4NOL A;  4F3E A;  4AHC A;  3IAY A;  4AYB A;  2YU9 A;  4GFQ A;  3CQZ A;  3GTK A;  2B9S B;  2A69 D;  4QIW A;  1Y1W A;  2E2I A;  4QCL A;  4KDD A;  5C9H A;  3GTG A;  1A31 A;  5CQG A;  1TL8 A;  1EK8 A;  4NOK A;  1R9T A;  4LMO A;  1A35 A;  2A6E D;  1SEU A;  4Q5V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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