4O26A

Crystal structure of the trbd domain of tert and the cr4/5 of tr
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
257
structure length
240
Chain Sequence
GSGFLYGGRGMHGFCLNRKRRTAAGPRRLQGQDLVRLVFFEGLKPKKLPLRYFNMVPVFGRLLQRHRKCRYSSVLHRMCPVVELSRAAQGELSSLIPQHCAPHRVYLFVRECLTAVVPEELWGSDHNRLQFFSRVRGFLKSGSVAELMWKIKVMDCDWLKLRRTAGRFPPSELAYRTRILSQFLTWLLDGFVVGLVRACFYATESNAIRFYRQEVWSKLQDLAFRRHIAKGEMEELSPAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for protein-RNA recognition in telomerase.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Oryzias latipes
molecule keywords Telomerase reverse transcriptase
total genus 76
structure length 240
sequence length 257
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2013-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12009 Telomerase_RBD Telomerase ribonucleoprotein complex - RNA binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.70 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4o26A00
4O26A 3KYLA 2R4GA 5C9HA 3DU6A 4LMOA 3DU5A 5CQGA
chains in the Genus database with same CATH superfamily
5JSBB 3K5OA 4NOLA 2NVYA 1LPQA 3K59A 3GTGA 3DU6A 1EJ9A 3GTPA 5CQGA 1A31A 4Q5GA 4O26A 1Y1WA 4KDDA 3DU5A 2NVXA 4IP9A 3K5LA 1ZYRD 4NOMA 4C2MA 3IAYA 1SMYD 2B63A 1I50A 3MAQA 4AYBA 1K4SA 3GTOA 4OYDB 1Q8IA 2CW0D 5C9HA 4QCLA 2R92A 3K58A 4EJ3A 2YU9A 1TWHA 2Y0SA 3CQZA 2E2HA 2R93A 4H3TA 3KYLA 1WQHA 1SC7A 1SFOA 2JA7A 1TGOA 4FGUA 4LMOA 3GTMA 1WQGA 1GE9A 3FKIA 1SEUA 4GFQA 1IW7D 1TWGA 2F4QA 3GTKA 3LF9A 2O5JD 2A6ED 5JSNB 2A68D 2A6HD 1Y1VA 3GTLA 1Y698 1RR8C 3H0GA 3K5MA 2JA5A 1IS1A 2WAQA 1TL8A 2R4GA 3SJRA 4IP8A 4F3EA 4KB4A 4D3YA 1R5ZA 3M4AA 2E2IA 1TWAA 3P9AA 4D3ZA 1DD5A 1K83A 1MIUA 3K5NA 4KC6A 3HKZA 1EK8A 3WVOA 4Q5VA 4FYDA 1R49A 1NH3A 1A35A 1RRJA 1HQMD 2BE5D 1WCMA 1YNJD 2R7ZA 2A69D 4FXDA 1V9MA 1I6VD 4AHCA 1T8IA 2VUMA 2WB1A 4QIWA 3GTJA 4AN8A 2B9SB 1TWFA 2JA6A 3LHPS 4NOKA 1TWCA 1I3QA 4L8IA 4KAWX 1YNND 5MLC9 1A36A 4JLRC 1R9TA 1WQFA 1K4TA 1ISEA 3GTQA 2PMZA 1EH1A 4KB2A 3K57A
chains in the Genus database with same CATH topology
5JSBB 3K5OA 4NOLA 2NVYA 1LPQA 3K59A 3GTGA 3DU6A 1EJ9A 3GTPA 5CQGA 1A31A 4Q5GA 4O26A 1Y1WA 4KDDA 3DU5A 2NVXA 4IP9A 3K5LA 1ZYRD 4NOMA 4C2MA 3IAYA 1SMYD 2B63A 1I50A 3MAQA 4AYBA 1K4SA 3GTOA 4OYDB 1Q8IA 2CW0D 5C9HA 4QCLA 2R92A 3K58A 4EJ3A 2YU9A 1TWHA 2Y0SA 3CQZA 2E2HA 2R93A 4H3TA 3KYLA 1WQHA 1SC7A 1SFOA 2JA7A 1TGOA 4FGUA 4LMOA 3GTMA 1WQGA 1GE9A 3FKIA 1SEUA 4GFQA 1IW7D 1TWGA 2F4QA 3GTKA 3LF9A 2O5JD 2A6ED 5JSNB 2A68D 2A6HD 1Y1VA 3GTLA 1Y698 1RR8C 3H0GA 3K5MA 2JA5A 1IS1A 2WAQA 1TL8A 2R4GA 3SJRA 4IP8A 4F3EA 4KB4A 4D3YA 1R5ZA 3M4AA 2E2IA 1TWAA 3P9AA 4D3ZA 1DD5A 1K83A 1MIUA 3K5NA 4KC6A 3HKZA 1EK8A 3WVOA 4Q5VA 4FYDA 1R49A 1NH3A 1A35A 1RRJA 1HQMD 2BE5D 1WCMA 1YNJD 2R7ZA 2A69D 4FXDA 1V9MA 1I6VD 4AHCA 1T8IA 2VUMA 2WB1A 4QIWA 3GTJA 4AN8A 2B9SB 1TWFA 2JA6A 3LHPS 4NOKA 1TWCA 1I3QA 4L8IA 4KAWX 1YNND 5MLC9 1A36A 4JLRC 1R9TA 1WQFA 1K4TA 1ISEA 3GTQA 2PMZA 1EH1A 4KB2A 3K57A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O26 A;  3KYL A;  2R4G A;  5C9H A;  3DU6 A;  4LMO A;  3DU5 A;  5CQG A; 
#chains in the Genus database with same CATH topology
 5JSB B;  3K5O A;  4NOL A;  2NVY A;  1LPQ A;  3K59 A;  3GTG A;  3DU6 A;  1EJ9 A;  3GTP A;  5CQG A;  1A31 A;  4Q5G A;  4O26 A;  1Y1W A;  4KDD A;  3DU5 A;  2NVX A;  4IP9 A;  3K5L A;  1ZYR D;  4NOM A;  4C2M A;  3IAY A;  1SMY D;  2B63 A;  1I50 A;  3MAQ A;  4AYB A;  1K4S A;  3GTO A;  4OYD B;  1Q8I A;  2CW0 D;  5C9H A;  4QCL A;  2R92 A;  3K58 A;  4EJ3 A;  2YU9 A;  1TWH A;  2Y0S A;  3CQZ A;  2E2H A;  2R93 A;  4H3T A;  3KYL A;  1WQH A;  1SC7 A;  1SFO A;  2JA7 A;  1TGO A;  4FGU A;  4LMO A;  3GTM A;  1WQG A;  1GE9 A;  3FKI A;  1SEU A;  4GFQ A;  1IW7 D;  1TWG A;  2F4Q A;  3GTK A;  3LF9 A;  2O5J D;  2A6E D;  5JSN B;  2A68 D;  2A6H D;  1Y1V A;  3GTL A;  1Y69 8;  1RR8 C;  3H0G A;  3K5M A;  2JA5 A;  1IS1 A;  2WAQ A;  1TL8 A;  2R4G A;  3SJR A;  4IP8 A;  4F3E A;  4KB4 A;  4D3Y A;  1R5Z A;  3M4A A;  2E2I A;  1TWA A;  3P9A A;  4D3Z A;  1DD5 A;  1K83 A;  1MIU A;  3K5N A;  4KC6 A;  3HKZ A;  1EK8 A;  3WVO A;  4Q5V A;  4FYD A;  1R49 A;  1NH3 A;  1A35 A;  1RRJ A;  1HQM D;  2BE5 D;  1WCM A;  1YNJ D;  2R7Z A;  2A69 D;  4FXD A;  1V9M A;  1I6V D;  4AHC A;  1T8I A;  2VUM A;  2WB1 A;  4QIW A;  3GTJ A;  4AN8 A;  2B9S B;  1TWF A;  2JA6 A;  3LHP S;  4NOK A;  1TWC A;  1I3Q A;  4L8I A;  4KAW X;  1YNN D;  5MLC 9;  1A36 A;  4JLR C;  1R9T A;  1WQF A;  1K4T A;  1ISE A;  3GTQ A;  2PMZ A;  1EH1 A;  4KB2 A;  3K57 A; 
#chains in the Genus database with same CATH homology
 5JSB B;  3K5O A;  4NOL A;  2NVY A;  1LPQ A;  3K59 A;  3GTG A;  3DU6 A;  1EJ9 A;  3GTP A;  5CQG A;  1A31 A;  4Q5G A;  4O26 A;  1Y1W A;  4KDD A;  3DU5 A;  2NVX A;  4IP9 A;  3K5L A;  1ZYR D;  4NOM A;  4C2M A;  3IAY A;  1SMY D;  2B63 A;  1I50 A;  3MAQ A;  4AYB A;  1K4S A;  3GTO A;  4OYD B;  1Q8I A;  2CW0 D;  5C9H A;  4QCL A;  2R92 A;  3K58 A;  4EJ3 A;  2YU9 A;  1TWH A;  2Y0S A;  3CQZ A;  2E2H A;  2R93 A;  4H3T A;  3KYL A;  1WQH A;  1SC7 A;  1SFO A;  2JA7 A;  1TGO A;  4FGU A;  4LMO A;  3GTM A;  1WQG A;  1GE9 A;  3FKI A;  1SEU A;  4GFQ A;  1IW7 D;  1TWG A;  2F4Q A;  3GTK A;  3LF9 A;  2O5J D;  2A6E D;  5JSN B;  2A68 D;  2A6H D;  1Y1V A;  3GTL A;  1Y69 8;  1RR8 C;  3H0G A;  3K5M A;  2JA5 A;  1IS1 A;  2WAQ A;  1TL8 A;  2R4G A;  3SJR A;  4IP8 A;  4F3E A;  4KB4 A;  4D3Y A;  1R5Z A;  3M4A A;  2E2I A;  1TWA A;  3P9A A;  4D3Z A;  1DD5 A;  1K83 A;  1MIU A;  3K5N A;  4KC6 A;  3HKZ A;  1EK8 A;  3WVO A;  4Q5V A;  4FYD A;  1R49 A;  1NH3 A;  1A35 A;  1RRJ A;  1HQM D;  2BE5 D;  1WCM A;  1YNJ D;  2R7Z A;  2A69 D;  4FXD A;  1V9M A;  1I6V D;  4AHC A;  1T8I A;  2VUM A;  2WB1 A;  4QIW A;  3GTJ A;  4AN8 A;  2B9S B;  1TWF A;  2JA6 A;  3LHP S;  4NOK A;  1TWC A;  1I3Q A;  4L8I A;  4KAW X;  1YNN D;  5MLC 9;  1A36 A;  4JLR C;  1R9T A;  1WQF A;  1K4T A;  1ISE A;  3GTQ A;  2PMZ A;  1EH1 A;  4KB2 A;  3K57 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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