4IP8A

Structure of human serum amyloid a1
Total Genus 47
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
105
structure length
105
Chain Sequence
MRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 47
structure length 105
sequence length 105
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip8A00
4IP8A 4Q5GA 4IP9A
chains in the Genus database with same CATH superfamily
2WAQA 1ISEA 3MAQA 3GTGA 1WCMA 2CW0D 3FKIA 3GTJA 1Y1VA 4O26A 3WVOA 2E2IA 2A6HD 1TWCA 3K5MA 5CQGA 1SMYD 1IW7D 3LHPS 1TWAA 1WQFA 3GTMA 1EK8A 4NOLA 4H3TA 1TGOA 2WB1A 2NVYA 1TWFA 1SFOA 1Y1WA 3CQZA 4NOKA 2O5JD 4D3ZA 1V9MA 1K4SA 4KB2A 4Q5GA 2E2HA 4FXDA 2Y0SA 1I50A 4Q5VA 2B9SB 1RR8C 1R49A 4LMOA 1YNND 1A36A 1T8IA 5JSBB 5MLC9 4AYBA 2R4GA 4GFQA 2JA6A 3IAYA 1HQMD 2PMZA 1Q8IA 1I3QA 2R7ZA 5JSNB 3K57A 4C2MA 3M4AA 4EJ3A 3KYLA 4F3EA 2F4QA 1IS1A 1EH1A 1I6VD 4QIWA 4KAWX 3H0GA 4KC6A 4IP8A 1K4TA 3GTLA 1LPQA 1A35A 3K5NA 2JA7A 4IP9A 2B63A 2YU9A 1WQGA 2BE5D 1MIUA 2A6ED 1TWGA 1WQHA 2JA5A 3LF9A 1TWHA 2NVXA 3GTQA 4KDDA 3P9AA 4AN8A 3GTOA 1NH3A 1YNJD 1R5ZA 2A68D 3DU5A 3K5OA 5C9HA 3K58A 1DD5A 1TL8A 1RRJA 3GTPA 1R9TA 3K5LA 3HKZA 1EJ9A 3K59A 4OYDB 1GE9A 4FYDA 4L8IA 1K83A 3SJRA 1SC7A 3DU6A 4JLRC 2A69D 4FGUA 1SEUA 4NOMA 2R93A 4QCLA 1A31A 3GTKA 1ZYRD 1Y698 4AHCA 2R92A 4D3YA 4KB4A 2VUMA
chains in the Genus database with same CATH topology
2WAQA 1ISEA 3MAQA 3GTGA 1WCMA 2CW0D 3FKIA 3GTJA 1Y1VA 4O26A 3WVOA 2E2IA 2A6HD 1TWCA 3K5MA 5CQGA 1SMYD 1IW7D 3LHPS 1TWAA 1WQFA 3GTMA 1EK8A 4NOLA 4H3TA 1TGOA 2WB1A 2NVYA 1TWFA 1SFOA 1Y1WA 3CQZA 4NOKA 2O5JD 4D3ZA 1V9MA 1K4SA 4KB2A 4Q5GA 2E2HA 4FXDA 2Y0SA 1I50A 4Q5VA 2B9SB 1RR8C 1R49A 4LMOA 1YNND 1A36A 1T8IA 5JSBB 5MLC9 4AYBA 2R4GA 4GFQA 2JA6A 3IAYA 1HQMD 2PMZA 1Q8IA 1I3QA 2R7ZA 5JSNB 3K57A 4C2MA 3M4AA 4EJ3A 3KYLA 4F3EA 2F4QA 1IS1A 1EH1A 1I6VD 4QIWA 4KAWX 3H0GA 4KC6A 4IP8A 1K4TA 3GTLA 1LPQA 1A35A 3K5NA 2JA7A 4IP9A 2B63A 2YU9A 1WQGA 2BE5D 1MIUA 2A6ED 1TWGA 1WQHA 2JA5A 3LF9A 1TWHA 2NVXA 3GTQA 4KDDA 3P9AA 4AN8A 3GTOA 1NH3A 1YNJD 1R5ZA 2A68D 3DU5A 3K5OA 5C9HA 3K58A 1DD5A 1TL8A 1RRJA 3GTPA 1R9TA 3K5LA 3HKZA 1EJ9A 3K59A 4OYDB 1GE9A 4FYDA 4L8IA 1K83A 3SJRA 1SC7A 3DU6A 4JLRC 2A69D 4FGUA 1SEUA 4NOMA 2R93A 4QCLA 1A31A 3GTKA 1ZYRD 1Y698 4AHCA 2R92A 4D3YA 4KB4A 2VUMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP8 A;  4Q5G A;  4IP9 A; 
#chains in the Genus database with same CATH topology
 2WAQ A;  1ISE A;  3MAQ A;  3GTG A;  1WCM A;  2CW0 D;  3FKI A;  3GTJ A;  1Y1V A;  4O26 A;  3WVO A;  2E2I A;  2A6H D;  1TWC A;  3K5M A;  5CQG A;  1SMY D;  1IW7 D;  3LHP S;  1TWA A;  1WQF A;  3GTM A;  1EK8 A;  4NOL A;  4H3T A;  1TGO A;  2WB1 A;  2NVY A;  1TWF A;  1SFO A;  1Y1W A;  3CQZ A;  4NOK A;  2O5J D;  4D3Z A;  1V9M A;  1K4S A;  4KB2 A;  4Q5G A;  2E2H A;  4FXD A;  2Y0S A;  1I50 A;  4Q5V A;  2B9S B;  1RR8 C;  1R49 A;  4LMO A;  1YNN D;  1A36 A;  1T8I A;  5JSB B;  5MLC 9;  4AYB A;  2R4G A;  4GFQ A;  2JA6 A;  3IAY A;  1HQM D;  2PMZ A;  1Q8I A;  1I3Q A;  2R7Z A;  5JSN B;  3K57 A;  4C2M A;  3M4A A;  4EJ3 A;  3KYL A;  4F3E A;  2F4Q A;  1IS1 A;  1EH1 A;  1I6V D;  4QIW A;  4KAW X;  3H0G A;  4KC6 A;  4IP8 A;  1K4T A;  3GTL A;  1LPQ A;  1A35 A;  3K5N A;  2JA7 A;  4IP9 A;  2B63 A;  2YU9 A;  1WQG A;  2BE5 D;  1MIU A;  2A6E D;  1TWG A;  1WQH A;  2JA5 A;  3LF9 A;  1TWH A;  2NVX A;  3GTQ A;  4KDD A;  3P9A A;  4AN8 A;  3GTO A;  1NH3 A;  1YNJ D;  1R5Z A;  2A68 D;  3DU5 A;  3K5O A;  5C9H A;  3K58 A;  1DD5 A;  1TL8 A;  1RRJ A;  3GTP A;  1R9T A;  3K5L A;  3HKZ A;  1EJ9 A;  3K59 A;  4OYD B;  1GE9 A;  4FYD A;  4L8I A;  1K83 A;  3SJR A;  1SC7 A;  3DU6 A;  4JLR C;  2A69 D;  4FGU A;  1SEU A;  4NOM A;  2R93 A;  4QCL A;  1A31 A;  3GTK A;  1ZYR D;  1Y69 8;  4AHC A;  2R92 A;  4D3Y A;  4KB4 A;  2VUM A; 
#chains in the Genus database with same CATH homology
 2WAQ A;  1ISE A;  3MAQ A;  3GTG A;  1WCM A;  2CW0 D;  3FKI A;  3GTJ A;  1Y1V A;  4O26 A;  3WVO A;  2E2I A;  2A6H D;  1TWC A;  3K5M A;  5CQG A;  1SMY D;  1IW7 D;  3LHP S;  1TWA A;  1WQF A;  3GTM A;  1EK8 A;  4NOL A;  4H3T A;  1TGO A;  2WB1 A;  2NVY A;  1TWF A;  1SFO A;  1Y1W A;  3CQZ A;  4NOK A;  2O5J D;  4D3Z A;  1V9M A;  1K4S A;  4KB2 A;  4Q5G A;  2E2H A;  4FXD A;  2Y0S A;  1I50 A;  4Q5V A;  2B9S B;  1RR8 C;  1R49 A;  4LMO A;  1YNN D;  1A36 A;  1T8I A;  5JSB B;  5MLC 9;  4AYB A;  2R4G A;  4GFQ A;  2JA6 A;  3IAY A;  1HQM D;  2PMZ A;  1Q8I A;  1I3Q A;  2R7Z A;  5JSN B;  3K57 A;  4C2M A;  3M4A A;  4EJ3 A;  3KYL A;  4F3E A;  2F4Q A;  1IS1 A;  1EH1 A;  1I6V D;  4QIW A;  4KAW X;  3H0G A;  4KC6 A;  4IP8 A;  1K4T A;  3GTL A;  1LPQ A;  1A35 A;  3K5N A;  2JA7 A;  4IP9 A;  2B63 A;  2YU9 A;  1WQG A;  2BE5 D;  1MIU A;  2A6E D;  1TWG A;  1WQH A;  2JA5 A;  3LF9 A;  1TWH A;  2NVX A;  3GTQ A;  4KDD A;  3P9A A;  4AN8 A;  3GTO A;  1NH3 A;  1YNJ D;  1R5Z A;  2A68 D;  3DU5 A;  3K5O A;  5C9H A;  3K58 A;  1DD5 A;  1TL8 A;  1RRJ A;  3GTP A;  1R9T A;  3K5L A;  3HKZ A;  1EJ9 A;  3K59 A;  4OYD B;  1GE9 A;  4FYD A;  4L8I A;  1K83 A;  3SJR A;  1SC7 A;  3DU6 A;  4JLR C;  2A69 D;  4FGU A;  1SEU A;  4NOM A;  2R93 A;  4QCL A;  1A31 A;  3GTK A;  1ZYR D;  1Y69 8;  4AHC A;  2R92 A;  4D3Y A;  4KB4 A;  2VUM A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...