4IP9A

Structure of native human serum amyloid a1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
104
structure length
104
Chain Sequence
RSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Serum amyloid A-1 protein
total genus 41
structure length 104
sequence length 104
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00277 SAA Serum amyloid A protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.110 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 4ip9A00
4IP9A 4Q5GA 4IP8A
chains in the Genus database with same CATH superfamily
2A6ED 1EJ9A 1A36A 4KC6A 4NOLA 2A69D 3GTJA 4NOMA 2PMZA 3KYLA 3DU5A 2YU9A 4OYDB 1SMYD 1TWAA 1WCMA 1YNJD 1A31A 1TWGA 1K4SA 2NVYA 4AHCA 1GE9A 1SEUA 1V9MA 3MAQA 1TGOA 4NOKA 1YNND 1SC7A 1RRJA 1TWCA 1WQHA 4D3ZA 2JA7A 4QIWA 4Q5VA 2WB1A 1ZYRD 1I50A 1Y1VA 3K5LA 2JA5A 3SJRA 4C2MA 2A68D 3K5OA 1A35A 2VUMA 1I6VD 5JSBB 5JSNB 2A6HD 2R93A 1K83A 5MLC9 4AYBA 3FKIA 3M4AA 3WVOA 3P9AA 1TWFA 4L8IA 2B63A 3K57A 3K59A 1T8IA 4F3EA 1Y1WA 3CQZA 1K4TA 3GTOA 4D3YA 2NVXA 3IAYA 2F4QA 1RR8C 4QCLA 2E2HA 1Y698 4EJ3A 1R9TA 3GTPA 4FYDA 2E2IA 3HKZA 1LPQA 3GTLA 1Q8IA 1R49A 3LHPS 1ISEA 1WQFA 5CQGA 1SFOA 1IS1A 3DU6A 4IP9A 3GTGA 1TL8A 1I3QA 4LMOA 4KB4A 2R4GA 3GTKA 3GTMA 4IP8A 1DD5A 4KDDA 1NH3A 2WAQA 1MIUA 4KB2A 2R7ZA 2Y0SA 4O26A 1IW7D 1EK8A 4FXDA 1WQGA 3K5MA 4Q5GA 3LF9A 2R92A 3K58A 2B9SB 1HQMD 1EH1A 1TWHA 4H3TA 4KAWX 5C9HA 3K5NA 2JA6A 4AN8A 2CW0D 4JLRC 1R5ZA 2O5JD 3GTQA 3H0GA 4GFQA 2BE5D 4FGUA
chains in the Genus database with same CATH topology
2A6ED 1EJ9A 1A36A 4KC6A 4NOLA 2A69D 3GTJA 4NOMA 2PMZA 3KYLA 3DU5A 2YU9A 4OYDB 1SMYD 1TWAA 1WCMA 1YNJD 1A31A 1TWGA 1K4SA 2NVYA 4AHCA 1GE9A 1SEUA 1V9MA 3MAQA 1TGOA 4NOKA 1YNND 1SC7A 1RRJA 1TWCA 1WQHA 4D3ZA 2JA7A 4QIWA 4Q5VA 2WB1A 1ZYRD 1I50A 1Y1VA 3K5LA 2JA5A 3SJRA 4C2MA 2A68D 3K5OA 1A35A 2VUMA 1I6VD 5JSBB 5JSNB 2A6HD 2R93A 1K83A 5MLC9 4AYBA 3FKIA 3M4AA 3WVOA 3P9AA 1TWFA 4L8IA 2B63A 3K57A 3K59A 1T8IA 4F3EA 1Y1WA 3CQZA 1K4TA 3GTOA 4D3YA 2NVXA 3IAYA 2F4QA 1RR8C 4QCLA 2E2HA 1Y698 4EJ3A 1R9TA 3GTPA 4FYDA 2E2IA 3HKZA 1LPQA 3GTLA 1Q8IA 1R49A 3LHPS 1ISEA 1WQFA 5CQGA 1SFOA 1IS1A 3DU6A 4IP9A 3GTGA 1TL8A 1I3QA 4LMOA 4KB4A 2R4GA 3GTKA 3GTMA 4IP8A 1DD5A 4KDDA 1NH3A 2WAQA 1MIUA 4KB2A 2R7ZA 2Y0SA 4O26A 1IW7D 1EK8A 4FXDA 1WQGA 3K5MA 4Q5GA 3LF9A 2R92A 3K58A 2B9SB 1HQMD 1EH1A 1TWHA 4H3TA 4KAWX 5C9HA 3K5NA 2JA6A 4AN8A 2CW0D 4JLRC 1R5ZA 2O5JD 3GTQA 3H0GA 4GFQA 2BE5D 4FGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IP9 A;  4Q5G A;  4IP8 A; 
#chains in the Genus database with same CATH topology
 2A6E D;  1EJ9 A;  1A36 A;  4KC6 A;  4NOL A;  2A69 D;  3GTJ A;  4NOM A;  2PMZ A;  3KYL A;  3DU5 A;  2YU9 A;  4OYD B;  1SMY D;  1TWA A;  1WCM A;  1YNJ D;  1A31 A;  1TWG A;  1K4S A;  2NVY A;  4AHC A;  1GE9 A;  1SEU A;  1V9M A;  3MAQ A;  1TGO A;  4NOK A;  1YNN D;  1SC7 A;  1RRJ A;  1TWC A;  1WQH A;  4D3Z A;  2JA7 A;  4QIW A;  4Q5V A;  2WB1 A;  1ZYR D;  1I50 A;  1Y1V A;  3K5L A;  2JA5 A;  3SJR A;  4C2M A;  2A68 D;  3K5O A;  1A35 A;  2VUM A;  1I6V D;  5JSB B;  5JSN B;  2A6H D;  2R93 A;  1K83 A;  5MLC 9;  4AYB A;  3FKI A;  3M4A A;  3WVO A;  3P9A A;  1TWF A;  4L8I A;  2B63 A;  3K57 A;  3K59 A;  1T8I A;  4F3E A;  1Y1W A;  3CQZ A;  1K4T A;  3GTO A;  4D3Y A;  2NVX A;  3IAY A;  2F4Q A;  1RR8 C;  4QCL A;  2E2H A;  1Y69 8;  4EJ3 A;  1R9T A;  3GTP A;  4FYD A;  2E2I A;  3HKZ A;  1LPQ A;  3GTL A;  1Q8I A;  1R49 A;  3LHP S;  1ISE A;  1WQF A;  5CQG A;  1SFO A;  1IS1 A;  3DU6 A;  4IP9 A;  3GTG A;  1TL8 A;  1I3Q A;  4LMO A;  4KB4 A;  2R4G A;  3GTK A;  3GTM A;  4IP8 A;  1DD5 A;  4KDD A;  1NH3 A;  2WAQ A;  1MIU A;  4KB2 A;  2R7Z A;  2Y0S A;  4O26 A;  1IW7 D;  1EK8 A;  4FXD A;  1WQG A;  3K5M A;  4Q5G A;  3LF9 A;  2R92 A;  3K58 A;  2B9S B;  1HQM D;  1EH1 A;  1TWH A;  4H3T A;  4KAW X;  5C9H A;  3K5N A;  2JA6 A;  4AN8 A;  2CW0 D;  4JLR C;  1R5Z A;  2O5J D;  3GTQ A;  3H0G A;  4GFQ A;  2BE5 D;  4FGU A; 
#chains in the Genus database with same CATH homology
 2A6E D;  1EJ9 A;  1A36 A;  4KC6 A;  4NOL A;  2A69 D;  3GTJ A;  4NOM A;  2PMZ A;  3KYL A;  3DU5 A;  2YU9 A;  4OYD B;  1SMY D;  1TWA A;  1WCM A;  1YNJ D;  1A31 A;  1TWG A;  1K4S A;  2NVY A;  4AHC A;  1GE9 A;  1SEU A;  1V9M A;  3MAQ A;  1TGO A;  4NOK A;  1YNN D;  1SC7 A;  1RRJ A;  1TWC A;  1WQH A;  4D3Z A;  2JA7 A;  4QIW A;  4Q5V A;  2WB1 A;  1ZYR D;  1I50 A;  1Y1V A;  3K5L A;  2JA5 A;  3SJR A;  4C2M A;  2A68 D;  3K5O A;  1A35 A;  2VUM A;  1I6V D;  5JSB B;  5JSN B;  2A6H D;  2R93 A;  1K83 A;  5MLC 9;  4AYB A;  3FKI A;  3M4A A;  3WVO A;  3P9A A;  1TWF A;  4L8I A;  2B63 A;  3K57 A;  3K59 A;  1T8I A;  4F3E A;  1Y1W A;  3CQZ A;  1K4T A;  3GTO A;  4D3Y A;  2NVX A;  3IAY A;  2F4Q A;  1RR8 C;  4QCL A;  2E2H A;  1Y69 8;  4EJ3 A;  1R9T A;  3GTP A;  4FYD A;  2E2I A;  3HKZ A;  1LPQ A;  3GTL A;  1Q8I A;  1R49 A;  3LHP S;  1ISE A;  1WQF A;  5CQG A;  1SFO A;  1IS1 A;  3DU6 A;  4IP9 A;  3GTG A;  1TL8 A;  1I3Q A;  4LMO A;  4KB4 A;  2R4G A;  3GTK A;  3GTM A;  4IP8 A;  1DD5 A;  4KDD A;  1NH3 A;  2WAQ A;  1MIU A;  4KB2 A;  2R7Z A;  2Y0S A;  4O26 A;  1IW7 D;  1EK8 A;  4FXD A;  1WQG A;  3K5M A;  4Q5G A;  3LF9 A;  2R92 A;  3K58 A;  2B9S B;  1HQM D;  1EH1 A;  1TWH A;  4H3T A;  4KAW X;  5C9H A;  3K5N A;  2JA6 A;  4AN8 A;  2CW0 D;  4JLR C;  1R5Z A;  2O5J D;  3GTQ A;  3H0G A;  4GFQ A;  2BE5 D;  4FGU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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