5C9HA

Structural basis of template boundary definition in tetrahymena telomerase
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
292
structure length
245
Chain Sequence
QYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of template-boundary definition in Tetrahymena telomerase.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Tetrahymena thermophila
molecule keywords Telomerase reverse transcriptase
total genus 72
structure length 245
sequence length 292
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2015-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12009 Telomerase_RBD Telomerase ribonucleoprotein complex - RNA binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.70 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 5c9hA01
3DU6A 3DU5A 5C9HA 4LMOA 4O26A 5CQGA 2R4GA 3KYLA
chains in the Genus database with same CATH superfamily
4C2MA 2PMZA 3FKIA 1ISEA 3K57A 2JA6A 2WB1A 2B9SB 1EK8A 1V9MA 4NOKA 4FYDA 2BE5D 5MLC9 3GTMA 4OYDB 3KYLA 1LPQA 2YU9A 1DD5A 1WQGA 3LF9A 2Y0SA 4AYBA 1Q8IA 4FGUA 1ZYRD 1IW7D 3DU5A 1R5ZA 3P9AA 2R93A 3HKZA 1EH1A 2R7ZA 3K5NA 3MAQA 2JA5A 1K83A 1I3QA 5JSBB 3LHPS 2A69D 1Y698 1TWFA 2CW0D 2A6ED 2E2HA 1TWHA 1YNJD 1A31A 4JLRC 4NOLA 2O5JD 1T8IA 3WVOA 3GTLA 4O26A 4Q5GA 2E2IA 1RR8C 4KAWX 1Y1WA 2A6HD 3GTPA 4Q5VA 4QIWA 2VUMA 1R49A 1NH3A 4IP8A 4GFQA 1SEUA 3H0GA 1TWAA 4KB2A 3K59A 1EJ9A 1RRJA 3M4AA 1TWGA 3K58A 1I6VD 1R9TA 4D3ZA 3DU6A 4EJ3A 1TGOA 4LMOA 1HQMD 4NOMA 2A68D 5CQGA 1A35A 4F3EA 4L8IA 2WAQA 3GTQA 1GE9A 4D3YA 3GTKA 1YNND 3K5LA 2B63A 3SJRA 1Y1VA 2F4QA 4H3TA 1TWCA 4AHCA 5JSNB 4KB4A 1SC7A 3GTGA 2NVXA 3K5MA 1K4SA 1A36A 2JA7A 3IAYA 2R92A 1TL8A 2NVYA 4IP9A 4QCLA 1WQHA 1WCMA 1K4TA 4KDDA 3K5OA 1SFOA 3GTJA 1IS1A 5C9HA 4KC6A 3GTOA 1MIUA 1SMYD 1WQFA 1I50A 4FXDA 2R4GA 3CQZA 4AN8A
chains in the Genus database with same CATH topology
4C2MA 2PMZA 3FKIA 1ISEA 3K57A 2JA6A 2WB1A 2B9SB 1EK8A 1V9MA 4NOKA 4FYDA 2BE5D 5MLC9 3GTMA 4OYDB 3KYLA 1LPQA 2YU9A 1DD5A 1WQGA 3LF9A 2Y0SA 4AYBA 1Q8IA 4FGUA 1ZYRD 1IW7D 3DU5A 1R5ZA 3P9AA 2R93A 3HKZA 1EH1A 2R7ZA 3K5NA 3MAQA 2JA5A 1K83A 1I3QA 5JSBB 3LHPS 2A69D 1Y698 1TWFA 2CW0D 2A6ED 2E2HA 1TWHA 1YNJD 1A31A 4JLRC 4NOLA 2O5JD 1T8IA 3WVOA 3GTLA 4O26A 4Q5GA 2E2IA 1RR8C 4KAWX 1Y1WA 2A6HD 3GTPA 4Q5VA 4QIWA 2VUMA 1R49A 1NH3A 4IP8A 4GFQA 1SEUA 3H0GA 1TWAA 4KB2A 3K59A 1EJ9A 1RRJA 3M4AA 1TWGA 3K58A 1I6VD 1R9TA 4D3ZA 3DU6A 4EJ3A 1TGOA 4LMOA 1HQMD 4NOMA 2A68D 5CQGA 1A35A 4F3EA 4L8IA 2WAQA 3GTQA 1GE9A 4D3YA 3GTKA 1YNND 3K5LA 2B63A 3SJRA 1Y1VA 2F4QA 4H3TA 1TWCA 4AHCA 5JSNB 4KB4A 1SC7A 3GTGA 2NVXA 3K5MA 1K4SA 1A36A 2JA7A 3IAYA 2R92A 1TL8A 2NVYA 4IP9A 4QCLA 1WQHA 1WCMA 1K4TA 4KDDA 3K5OA 1SFOA 3GTJA 1IS1A 5C9HA 4KC6A 3GTOA 1MIUA 1SMYD 1WQFA 1I50A 4FXDA 2R4GA 3CQZA 4AN8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DU6 A;  3DU5 A;  5C9H A;  4LMO A;  4O26 A;  5CQG A;  2R4G A;  3KYL A; 
#chains in the Genus database with same CATH topology
 4C2M A;  2PMZ A;  3FKI A;  1ISE A;  3K57 A;  2JA6 A;  2WB1 A;  2B9S B;  1EK8 A;  1V9M A;  4NOK A;  4FYD A;  2BE5 D;  5MLC 9;  3GTM A;  4OYD B;  3KYL A;  1LPQ A;  2YU9 A;  1DD5 A;  1WQG A;  3LF9 A;  2Y0S A;  4AYB A;  1Q8I A;  4FGU A;  1ZYR D;  1IW7 D;  3DU5 A;  1R5Z A;  3P9A A;  2R93 A;  3HKZ A;  1EH1 A;  2R7Z A;  3K5N A;  3MAQ A;  2JA5 A;  1K83 A;  1I3Q A;  5JSB B;  3LHP S;  2A69 D;  1Y69 8;  1TWF A;  2CW0 D;  2A6E D;  2E2H A;  1TWH A;  1YNJ D;  1A31 A;  4JLR C;  4NOL A;  2O5J D;  1T8I A;  3WVO A;  3GTL A;  4O26 A;  4Q5G A;  2E2I A;  1RR8 C;  4KAW X;  1Y1W A;  2A6H D;  3GTP A;  4Q5V A;  4QIW A;  2VUM A;  1R49 A;  1NH3 A;  4IP8 A;  4GFQ A;  1SEU A;  3H0G A;  1TWA A;  4KB2 A;  3K59 A;  1EJ9 A;  1RRJ A;  3M4A A;  1TWG A;  3K58 A;  1I6V D;  1R9T A;  4D3Z A;  3DU6 A;  4EJ3 A;  1TGO A;  4LMO A;  1HQM D;  4NOM A;  2A68 D;  5CQG A;  1A35 A;  4F3E A;  4L8I A;  2WAQ A;  3GTQ A;  1GE9 A;  4D3Y A;  3GTK A;  1YNN D;  3K5L A;  2B63 A;  3SJR A;  1Y1V A;  2F4Q A;  4H3T A;  1TWC A;  4AHC A;  5JSN B;  4KB4 A;  1SC7 A;  3GTG A;  2NVX A;  3K5M A;  1K4S A;  1A36 A;  2JA7 A;  3IAY A;  2R92 A;  1TL8 A;  2NVY A;  4IP9 A;  4QCL A;  1WQH A;  1WCM A;  1K4T A;  4KDD A;  3K5O A;  1SFO A;  3GTJ A;  1IS1 A;  5C9H A;  4KC6 A;  3GTO A;  1MIU A;  1SMY D;  1WQF A;  1I50 A;  4FXD A;  2R4G A;  3CQZ A;  4AN8 A; 
#chains in the Genus database with same CATH homology
 4C2M A;  2PMZ A;  3FKI A;  1ISE A;  3K57 A;  2JA6 A;  2WB1 A;  2B9S B;  1EK8 A;  1V9M A;  4NOK A;  4FYD A;  2BE5 D;  5MLC 9;  3GTM A;  4OYD B;  3KYL A;  1LPQ A;  2YU9 A;  1DD5 A;  1WQG A;  3LF9 A;  2Y0S A;  4AYB A;  1Q8I A;  4FGU A;  1ZYR D;  1IW7 D;  3DU5 A;  1R5Z A;  3P9A A;  2R93 A;  3HKZ A;  1EH1 A;  2R7Z A;  3K5N A;  3MAQ A;  2JA5 A;  1K83 A;  1I3Q A;  5JSB B;  3LHP S;  2A69 D;  1Y69 8;  1TWF A;  2CW0 D;  2A6E D;  2E2H A;  1TWH A;  1YNJ D;  1A31 A;  4JLR C;  4NOL A;  2O5J D;  1T8I A;  3WVO A;  3GTL A;  4O26 A;  4Q5G A;  2E2I A;  1RR8 C;  4KAW X;  1Y1W A;  2A6H D;  3GTP A;  4Q5V A;  4QIW A;  2VUM A;  1R49 A;  1NH3 A;  4IP8 A;  4GFQ A;  1SEU A;  3H0G A;  1TWA A;  4KB2 A;  3K59 A;  1EJ9 A;  1RRJ A;  3M4A A;  1TWG A;  3K58 A;  1I6V D;  1R9T A;  4D3Z A;  3DU6 A;  4EJ3 A;  1TGO A;  4LMO A;  1HQM D;  4NOM A;  2A68 D;  5CQG A;  1A35 A;  4F3E A;  4L8I A;  2WAQ A;  3GTQ A;  1GE9 A;  4D3Y A;  3GTK A;  1YNN D;  3K5L A;  2B63 A;  3SJR A;  1Y1V A;  2F4Q A;  4H3T A;  1TWC A;  4AHC A;  5JSN B;  4KB4 A;  1SC7 A;  3GTG A;  2NVX A;  3K5M A;  1K4S A;  1A36 A;  2JA7 A;  3IAY A;  2R92 A;  1TL8 A;  2NVY A;  4IP9 A;  4QCL A;  1WQH A;  1WCM A;  1K4T A;  4KDD A;  3K5O A;  1SFO A;  3GTJ A;  1IS1 A;  5C9H A;  4KC6 A;  3GTO A;  1MIU A;  1SMY D;  1WQF A;  1I50 A;  4FXD A;  2R4G A;  3CQZ A;  4AN8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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