5C9HA

Structural basis of template boundary definition in tetrahymena telomerase
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
292
structure length
245
Chain Sequence
QYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of template-boundary definition in Tetrahymena telomerase.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Tetrahymena thermophila
molecule keywords Telomerase reverse transcriptase
total genus 72
structure length 245
sequence length 292
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2015-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12009 Telomerase_RBD Telomerase ribonucleoprotein complex - RNA binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.70 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 5c9hA01
3KYLA 3DU6A 4O26A 5CQGA 2R4GA 5C9HA 4LMOA 3DU5A
chains in the Genus database with same CATH superfamily
3GTJA 3LHPS 4KB2A 4O26A 1ISEA 4IP9A 4D3YA 1TWGA 2WAQA 4FXDA 3WVOA 4L8IA 2JA5A 1YNND 1R5ZA 3DU5A 1TGOA 4KAWX 1Y698 1RR8C 5JSBB 1SFOA 3H0GA 1I3QA 2JA7A 1TWFA 2E2IA 1Y1WA 2PMZA 3K58A 5C9HA 2NVYA 1EK8A 4KDDA 1WCMA 2Y0SA 1WQHA 4JLRC 1IW7D 1MIUA 3DU6A 4C2MA 1DD5A 2WB1A 2JA6A 2YU9A 3CQZA 4AHCA 1RRJA 4NOLA 3KYLA 4F3EA 1TWAA 1K4TA 3GTQA 4OYDB 3GTMA 4Q5VA 2R93A 4KB4A 2A6HD 1IS1A 5MLC9 1R49A 4KC6A 3GTPA 1SMYD 1R9TA 1YNJD 4D3ZA 2R92A 3FKIA 1Y1VA 2B63A 1ZYRD 2CW0D 3SJRA 4GFQA 3K5MA 1WQFA 3IAYA 2R4GA 3M4AA 1Q8IA 4FYDA 2O5JD 4NOMA 3P9AA 3GTGA 2R7ZA 1A36A 4AYBA 4AN8A 1TWCA 1K4SA 2A68D 4Q5GA 3GTOA 1I6VD 1HQMD 1K83A 3K5LA 3GTKA 2F4QA 4H3TA 1LPQA 1T8IA 3K59A 1NH3A 5CQGA 3K57A 1TL8A 3HKZA 1TWHA 1I50A 4QIWA 3LF9A 4QCLA 2A6ED 1EH1A 1A35A 2NVXA 1EJ9A 2E2HA 2A69D 1SC7A 3K5NA 2B9SB 1GE9A 4IP8A 1V9MA 1WQGA 4FGUA 4LMOA 4NOKA 3K5OA 3GTLA 1A31A 1SEUA 2VUMA 5JSNB 2BE5D 4EJ3A 3MAQA
chains in the Genus database with same CATH topology
3GTJA 3LHPS 4KB2A 4O26A 1ISEA 4IP9A 4D3YA 1TWGA 2WAQA 4FXDA 3WVOA 4L8IA 2JA5A 1YNND 1R5ZA 3DU5A 1TGOA 4KAWX 1Y698 1RR8C 5JSBB 1SFOA 3H0GA 1I3QA 2JA7A 1TWFA 2E2IA 1Y1WA 2PMZA 3K58A 5C9HA 2NVYA 1EK8A 4KDDA 1WCMA 2Y0SA 1WQHA 4JLRC 1IW7D 1MIUA 3DU6A 4C2MA 1DD5A 2WB1A 2JA6A 2YU9A 3CQZA 4AHCA 1RRJA 4NOLA 3KYLA 4F3EA 1TWAA 1K4TA 3GTQA 4OYDB 3GTMA 4Q5VA 2R93A 4KB4A 2A6HD 1IS1A 5MLC9 1R49A 4KC6A 3GTPA 1SMYD 1R9TA 1YNJD 4D3ZA 2R92A 3FKIA 1Y1VA 2B63A 1ZYRD 2CW0D 3SJRA 4GFQA 3K5MA 1WQFA 3IAYA 2R4GA 3M4AA 1Q8IA 4FYDA 2O5JD 4NOMA 3P9AA 3GTGA 2R7ZA 1A36A 4AYBA 4AN8A 1TWCA 1K4SA 2A68D 4Q5GA 3GTOA 1I6VD 1HQMD 1K83A 3K5LA 3GTKA 2F4QA 4H3TA 1LPQA 1T8IA 3K59A 1NH3A 5CQGA 3K57A 1TL8A 3HKZA 1TWHA 1I50A 4QIWA 3LF9A 4QCLA 2A6ED 1EH1A 1A35A 2NVXA 1EJ9A 2E2HA 2A69D 1SC7A 3K5NA 2B9SB 1GE9A 4IP8A 1V9MA 1WQGA 4FGUA 4LMOA 4NOKA 3K5OA 3GTLA 1A31A 1SEUA 2VUMA 5JSNB 2BE5D 4EJ3A 3MAQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KYL A;  3DU6 A;  4O26 A;  5CQG A;  2R4G A;  5C9H A;  4LMO A;  3DU5 A; 
#chains in the Genus database with same CATH topology
 3GTJ A;  3LHP S;  4KB2 A;  4O26 A;  1ISE A;  4IP9 A;  4D3Y A;  1TWG A;  2WAQ A;  4FXD A;  3WVO A;  4L8I A;  2JA5 A;  1YNN D;  1R5Z A;  3DU5 A;  1TGO A;  4KAW X;  1Y69 8;  1RR8 C;  5JSB B;  1SFO A;  3H0G A;  1I3Q A;  2JA7 A;  1TWF A;  2E2I A;  1Y1W A;  2PMZ A;  3K58 A;  5C9H A;  2NVY A;  1EK8 A;  4KDD A;  1WCM A;  2Y0S A;  1WQH A;  4JLR C;  1IW7 D;  1MIU A;  3DU6 A;  4C2M A;  1DD5 A;  2WB1 A;  2JA6 A;  2YU9 A;  3CQZ A;  4AHC A;  1RRJ A;  4NOL A;  3KYL A;  4F3E A;  1TWA A;  1K4T A;  3GTQ A;  4OYD B;  3GTM A;  4Q5V A;  2R93 A;  4KB4 A;  2A6H D;  1IS1 A;  5MLC 9;  1R49 A;  4KC6 A;  3GTP A;  1SMY D;  1R9T A;  1YNJ D;  4D3Z A;  2R92 A;  3FKI A;  1Y1V A;  2B63 A;  1ZYR D;  2CW0 D;  3SJR A;  4GFQ A;  3K5M A;  1WQF A;  3IAY A;  2R4G A;  3M4A A;  1Q8I A;  4FYD A;  2O5J D;  4NOM A;  3P9A A;  3GTG A;  2R7Z A;  1A36 A;  4AYB A;  4AN8 A;  1TWC A;  1K4S A;  2A68 D;  4Q5G A;  3GTO A;  1I6V D;  1HQM D;  1K83 A;  3K5L A;  3GTK A;  2F4Q A;  4H3T A;  1LPQ A;  1T8I A;  3K59 A;  1NH3 A;  5CQG A;  3K57 A;  1TL8 A;  3HKZ A;  1TWH A;  1I50 A;  4QIW A;  3LF9 A;  4QCL A;  2A6E D;  1EH1 A;  1A35 A;  2NVX A;  1EJ9 A;  2E2H A;  2A69 D;  1SC7 A;  3K5N A;  2B9S B;  1GE9 A;  4IP8 A;  1V9M A;  1WQG A;  4FGU A;  4LMO A;  4NOK A;  3K5O A;  3GTL A;  1A31 A;  1SEU A;  2VUM A;  5JSN B;  2BE5 D;  4EJ3 A;  3MAQ A; 
#chains in the Genus database with same CATH homology
 3GTJ A;  3LHP S;  4KB2 A;  4O26 A;  1ISE A;  4IP9 A;  4D3Y A;  1TWG A;  2WAQ A;  4FXD A;  3WVO A;  4L8I A;  2JA5 A;  1YNN D;  1R5Z A;  3DU5 A;  1TGO A;  4KAW X;  1Y69 8;  1RR8 C;  5JSB B;  1SFO A;  3H0G A;  1I3Q A;  2JA7 A;  1TWF A;  2E2I A;  1Y1W A;  2PMZ A;  3K58 A;  5C9H A;  2NVY A;  1EK8 A;  4KDD A;  1WCM A;  2Y0S A;  1WQH A;  4JLR C;  1IW7 D;  1MIU A;  3DU6 A;  4C2M A;  1DD5 A;  2WB1 A;  2JA6 A;  2YU9 A;  3CQZ A;  4AHC A;  1RRJ A;  4NOL A;  3KYL A;  4F3E A;  1TWA A;  1K4T A;  3GTQ A;  4OYD B;  3GTM A;  4Q5V A;  2R93 A;  4KB4 A;  2A6H D;  1IS1 A;  5MLC 9;  1R49 A;  4KC6 A;  3GTP A;  1SMY D;  1R9T A;  1YNJ D;  4D3Z A;  2R92 A;  3FKI A;  1Y1V A;  2B63 A;  1ZYR D;  2CW0 D;  3SJR A;  4GFQ A;  3K5M A;  1WQF A;  3IAY A;  2R4G A;  3M4A A;  1Q8I A;  4FYD A;  2O5J D;  4NOM A;  3P9A A;  3GTG A;  2R7Z A;  1A36 A;  4AYB A;  4AN8 A;  1TWC A;  1K4S A;  2A68 D;  4Q5G A;  3GTO A;  1I6V D;  1HQM D;  1K83 A;  3K5L A;  3GTK A;  2F4Q A;  4H3T A;  1LPQ A;  1T8I A;  3K59 A;  1NH3 A;  5CQG A;  3K57 A;  1TL8 A;  3HKZ A;  1TWH A;  1I50 A;  4QIW A;  3LF9 A;  4QCL A;  2A6E D;  1EH1 A;  1A35 A;  2NVX A;  1EJ9 A;  2E2H A;  2A69 D;  1SC7 A;  3K5N A;  2B9S B;  1GE9 A;  4IP8 A;  1V9M A;  1WQG A;  4FGU A;  4LMO A;  4NOK A;  3K5O A;  3GTL A;  1A31 A;  1SEU A;  2VUM A;  5JSN B;  2BE5 D;  4EJ3 A;  3MAQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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