5C9HA

Structural basis of template boundary definition in tetrahymena telomerase
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
292
structure length
245
Chain Sequence
QYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of template-boundary definition in Tetrahymena telomerase.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Tetrahymena thermophila
molecule keywords Telomerase reverse transcriptase
total genus 72
structure length 245
sequence length 292
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2015-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF12009 Telomerase_RBD Telomerase ribonucleoprotein complex - RNA binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.70 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 5c9hA01
3DU5A 4LMOA 3KYLA 4O26A 5C9HA 5CQGA 2R4GA 3DU6A
chains in the Genus database with same CATH superfamily
1TGOA 1HQMD 2O5JD 3DU5A 4KDDA 4OYDB 4Q5VA 1Y1VA 2CW0D 3LHPS 1SEUA 4QIWA 3MAQA 1EH1A 4FXDA 3K58A 4D3YA 2YU9A 3K5OA 1RR8C 2NVYA 3GTOA 1SMYD 2JA6A 1WCMA 2A69D 1TWHA 4IP8A 1R9TA 2E2IA 1WQHA 3LF9A 3KYLA 2B9SB 1A35A 1R49A 1K83A 2R4GA 1I50A 1SC7A 5MLC9 5C9HA 1YNJD 1R5ZA 4FGUA 4AN8A 1A31A 1TWAA 2JA7A 1DD5A 4AHCA 1Y698 4LMOA 1SFOA 1A36A 2Y0SA 2WB1A 1IW7D 3GTMA 4KAWX 2A68D 4O26A 2E2HA 3K5LA 4NOLA 3K59A 3IAYA 1GE9A 1NH3A 1EJ9A 1ISEA 3WVOA 3GTKA 3K57A 1RRJA 3P9AA 2R92A 1Y1WA 3K5MA 1K4TA 2NVXA 3GTPA 5CQGA 3K5NA 1LPQA 2JA5A 3DU6A 1TWFA 3GTLA 1I6VD 2PMZA 2R7ZA 4NOMA 2R93A 1T8IA 4QCLA 4KB4A 2A6ED 4GFQA 2WAQA 2A6HD 2B63A 1V9MA 2BE5D 3FKIA 1TL8A 4KB2A 1K4SA 4H3TA 3CQZA 1EK8A 4AYBA 2F4QA 1Q8IA 3GTQA 3H0GA 4JLRC 3GTGA 1I3QA 2VUMA 4IP9A 4D3ZA 3GTJA 4Q5GA 1WQFA 1WQGA 4FYDA 1TWGA 4NOKA 4KC6A 1IS1A 3SJRA 1ZYRD 5JSBB 4EJ3A 4L8IA 1YNND 4C2MA 4F3EA 5JSNB 3M4AA 3HKZA 1MIUA 1TWCA
chains in the Genus database with same CATH topology
1TGOA 1HQMD 2O5JD 3DU5A 4KDDA 4OYDB 4Q5VA 1Y1VA 2CW0D 3LHPS 1SEUA 4QIWA 3MAQA 1EH1A 4FXDA 3K58A 4D3YA 2YU9A 3K5OA 1RR8C 2NVYA 3GTOA 1SMYD 2JA6A 1WCMA 2A69D 1TWHA 4IP8A 1R9TA 2E2IA 1WQHA 3LF9A 3KYLA 2B9SB 1A35A 1R49A 1K83A 2R4GA 1I50A 1SC7A 5MLC9 5C9HA 1YNJD 1R5ZA 4FGUA 4AN8A 1A31A 1TWAA 2JA7A 1DD5A 4AHCA 1Y698 4LMOA 1SFOA 1A36A 2Y0SA 2WB1A 1IW7D 3GTMA 4KAWX 2A68D 4O26A 2E2HA 3K5LA 4NOLA 3K59A 3IAYA 1GE9A 1NH3A 1EJ9A 1ISEA 3WVOA 3GTKA 3K57A 1RRJA 3P9AA 2R92A 1Y1WA 3K5MA 1K4TA 2NVXA 3GTPA 5CQGA 3K5NA 1LPQA 2JA5A 3DU6A 1TWFA 3GTLA 1I6VD 2PMZA 2R7ZA 4NOMA 2R93A 1T8IA 4QCLA 4KB4A 2A6ED 4GFQA 2WAQA 2A6HD 2B63A 1V9MA 2BE5D 3FKIA 1TL8A 4KB2A 1K4SA 4H3TA 3CQZA 1EK8A 4AYBA 2F4QA 1Q8IA 3GTQA 3H0GA 4JLRC 3GTGA 1I3QA 2VUMA 4IP9A 4D3ZA 3GTJA 4Q5GA 1WQFA 1WQGA 4FYDA 1TWGA 4NOKA 4KC6A 1IS1A 3SJRA 1ZYRD 5JSBB 4EJ3A 4L8IA 1YNND 4C2MA 4F3EA 5JSNB 3M4AA 3HKZA 1MIUA 1TWCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DU5 A;  4LMO A;  3KYL A;  4O26 A;  5C9H A;  5CQG A;  2R4G A;  3DU6 A; 
#chains in the Genus database with same CATH topology
 1TGO A;  1HQM D;  2O5J D;  3DU5 A;  4KDD A;  4OYD B;  4Q5V A;  1Y1V A;  2CW0 D;  3LHP S;  1SEU A;  4QIW A;  3MAQ A;  1EH1 A;  4FXD A;  3K58 A;  4D3Y A;  2YU9 A;  3K5O A;  1RR8 C;  2NVY A;  3GTO A;  1SMY D;  2JA6 A;  1WCM A;  2A69 D;  1TWH A;  4IP8 A;  1R9T A;  2E2I A;  1WQH A;  3LF9 A;  3KYL A;  2B9S B;  1A35 A;  1R49 A;  1K83 A;  2R4G A;  1I50 A;  1SC7 A;  5MLC 9;  5C9H A;  1YNJ D;  1R5Z A;  4FGU A;  4AN8 A;  1A31 A;  1TWA A;  2JA7 A;  1DD5 A;  4AHC A;  1Y69 8;  4LMO A;  1SFO A;  1A36 A;  2Y0S A;  2WB1 A;  1IW7 D;  3GTM A;  4KAW X;  2A68 D;  4O26 A;  2E2H A;  3K5L A;  4NOL A;  3K59 A;  3IAY A;  1GE9 A;  1NH3 A;  1EJ9 A;  1ISE A;  3WVO A;  3GTK A;  3K57 A;  1RRJ A;  3P9A A;  2R92 A;  1Y1W A;  3K5M A;  1K4T A;  2NVX A;  3GTP A;  5CQG A;  3K5N A;  1LPQ A;  2JA5 A;  3DU6 A;  1TWF A;  3GTL A;  1I6V D;  2PMZ A;  2R7Z A;  4NOM A;  2R93 A;  1T8I A;  4QCL A;  4KB4 A;  2A6E D;  4GFQ A;  2WAQ A;  2A6H D;  2B63 A;  1V9M A;  2BE5 D;  3FKI A;  1TL8 A;  4KB2 A;  1K4S A;  4H3T A;  3CQZ A;  1EK8 A;  4AYB A;  2F4Q A;  1Q8I A;  3GTQ A;  3H0G A;  4JLR C;  3GTG A;  1I3Q A;  2VUM A;  4IP9 A;  4D3Z A;  3GTJ A;  4Q5G A;  1WQF A;  1WQG A;  4FYD A;  1TWG A;  4NOK A;  4KC6 A;  1IS1 A;  3SJR A;  1ZYR D;  5JSB B;  4EJ3 A;  4L8I A;  1YNN D;  4C2M A;  4F3E A;  5JSN B;  3M4A A;  3HKZ A;  1MIU A;  1TWC A; 
#chains in the Genus database with same CATH homology
 1TGO A;  1HQM D;  2O5J D;  3DU5 A;  4KDD A;  4OYD B;  4Q5V A;  1Y1V A;  2CW0 D;  3LHP S;  1SEU A;  4QIW A;  3MAQ A;  1EH1 A;  4FXD A;  3K58 A;  4D3Y A;  2YU9 A;  3K5O A;  1RR8 C;  2NVY A;  3GTO A;  1SMY D;  2JA6 A;  1WCM A;  2A69 D;  1TWH A;  4IP8 A;  1R9T A;  2E2I A;  1WQH A;  3LF9 A;  3KYL A;  2B9S B;  1A35 A;  1R49 A;  1K83 A;  2R4G A;  1I50 A;  1SC7 A;  5MLC 9;  5C9H A;  1YNJ D;  1R5Z A;  4FGU A;  4AN8 A;  1A31 A;  1TWA A;  2JA7 A;  1DD5 A;  4AHC A;  1Y69 8;  4LMO A;  1SFO A;  1A36 A;  2Y0S A;  2WB1 A;  1IW7 D;  3GTM A;  4KAW X;  2A68 D;  4O26 A;  2E2H A;  3K5L A;  4NOL A;  3K59 A;  3IAY A;  1GE9 A;  1NH3 A;  1EJ9 A;  1ISE A;  3WVO A;  3GTK A;  3K57 A;  1RRJ A;  3P9A A;  2R92 A;  1Y1W A;  3K5M A;  1K4T A;  2NVX A;  3GTP A;  5CQG A;  3K5N A;  1LPQ A;  2JA5 A;  3DU6 A;  1TWF A;  3GTL A;  1I6V D;  2PMZ A;  2R7Z A;  4NOM A;  2R93 A;  1T8I A;  4QCL A;  4KB4 A;  2A6E D;  4GFQ A;  2WAQ A;  2A6H D;  2B63 A;  1V9M A;  2BE5 D;  3FKI A;  1TL8 A;  4KB2 A;  1K4S A;  4H3T A;  3CQZ A;  1EK8 A;  4AYB A;  2F4Q A;  1Q8I A;  3GTQ A;  3H0G A;  4JLR C;  3GTG A;  1I3Q A;  2VUM A;  4IP9 A;  4D3Z A;  3GTJ A;  4Q5G A;  1WQF A;  1WQG A;  4FYD A;  1TWG A;  4NOK A;  4KC6 A;  1IS1 A;  3SJR A;  1ZYR D;  5JSB B;  4EJ3 A;  4L8I A;  1YNN D;  4C2M A;  4F3E A;  5JSN B;  3M4A A;  3HKZ A;  1MIU A;  1TWC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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