2HHHD

Crystal structure of kasugamycin bound to the 30s ribosomal subunit
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
208
structure length
208
Chain Sequence
GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 16S ribosomal RNA
total genus 58
structure length 208
sequence length 208
ec nomenclature
pdb deposition date 2006-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00163 Ribosomal_S4 Ribosomal protein S4/S9 N-terminal domain
D PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1050.10 Mainly Alpha Orthogonal Bundle Ribosomal Protein S4 Delta 41; Chain A, domain 1 Ribosomal Protein S4 Delta 41; Chain A, domain 1 2hhhD01
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 2hhhD02
5LMND 1C06A 1KSKA 4DV5D 4X66D 4X64D 4JI6D 2JANA 4DV0D 4JI7D 5LMUD 4DUZD 1N34D 2UXCD 4DV1D 1HNWD 4JV5D 4LFBD 4GKKD 4LFCD 4DR4D 1J5ED 1P9KA 4X65D 2UUCD 4NXND 1HR0D 5BR8D 4JI2D 4KHPD 3HP7A 4JI3D 4JI0D 4K0KD 1HNXD 4DR2D 2HHHD 4LF7D 4YY3D 1N33D 1XMOD 4LF9D 2K6PA 1IBKD 4GKJD 1XNRD 4DR3D 4NXMD 1DM9A 3T1YD 5IWAD 4DR6D 3OTOD 4DV6D 4OX9D 4DV3D 1XMQD 4LFAD 4YHHD 4JI1D 3T1HD 4B3SD 4B3TD 4OUDA 1IBMD 2F4VD 4DV4D 4DR5D 1IBLD 4LF6D 1FJGD 4DV2D 4X62D 2UUAD 4LF5D 2UUBD 4DR7D 2ZM6D 4JI4D 4LF8D 3DH3A 1KSVA 2ISTA 1JH3A 1XNQD 1VIOA 1HNZD 4JI5D 3KBGA 4B3RD 1N36D 2UXBD 4B3MD 1FKAD 1H3EA 1C05A 2E5LD 4JI8D 2VQFD 4DV7D 2VQED 4AQYD 4LGTA 2KTLA 4DR1D 4JYAD 1N32D 2UU9D 1KSLA 2UXDD 1H3FA 4DUYD 1I94D 4LF4D
chains in the Genus database with same CATH superfamily
5LMND 1C06A 1KSKA 4DV5D 3ONGA 4X66D 3FN1A 2I1SA 4X64D 4JI6D 2JANA 4NNJA 4DV0D 4JI7D 5LMUD 4DUZD 1N34D 3ONHA 2UXCD 4DV1D 1Y8XB 2ZTBA 3KYCB 1HNWD 4JV5D 4LFBD 4W5VB 4GKKD 4LFCD 4DR4D 1J5ED 1P9KA 4X65D 4II2A 5A2QE 1Y8QB 2UUCD 4NXND 1HR0D 5BR8D 4JI2D 4KHPD 3HP7A 4JI3D 4JI0D 4K0KD 1HNXD 4DR2D 3KYDB 2HHHD 3J80E 2L3NA 4LF7D 4YY3D 1N33D 1XMOD 4LF9D 2K6PA 1IBKD 4GKJD 1XNRD 3J7AF 4DR3D 4NXMD 1DM9A 3T1YD 5IWAD 4DR6D 5FLXE 3OTOD 4DV6D 4OX9D 4DV3D 1XMQD 4LFAD 5LL6S 4II3A 4YHHD 4JI1D 3T1HD 4B3SD 4B3TD 4OUDA 3CMMA 1IBMD 3J81E 2F4VD 4DV4D 4DR5D 1IBLD 4LF6D 5FQ2B 5KNLA 5IT9E 2LQ7A 1FJGD 4DV2D 2NVUB 4X62D 2UUAD 4LF5D 2UUBD 4DR7D 2ZM6D 4JI4D 4LF8D 3DH3A 3JAME 1KSVA 2ISTA 1JH3A 1XNQD 1VIOA 1HNZD 4JI5D 3KBGA 4B3RD 1N36D 2UXBD 4B3MD 1FKAD 1H3EA 1C05A 2E5LD 4JI8D 2VQFD 4DV7D 2VQED 4AQYD 4LGTA 2KTLA 4DR1D 4JYAD 1N32D 2UU9D 1KSLA 2UXDD 1Y8RB 1H3FA 4DUYD 1I94D 4LF4D
chains in the Genus database with same CATH topology
5LMND 1C06A 1KSKA 4DV5D 4X66D 4X64D 4JI6D 2JANA 4DV0D 4JI7D 5LMUD 4DUZD 1N34D 2UXCD 4DV1D 1HNWD 4JV5D 4LFBD 4GKKD 4LFCD 4DR4D 1J5ED 1P9KA 4X65D 2UUCD 4NXND 1HR0D 5BR8D 4JI2D 4KHPD 3HP7A 4JI3D 4JI0D 4K0KD 1HNXD 4DR2D 2HHHD 2L3NA 4LF7D 4YY3D 1N33D 1XMOD 4LF9D 2K6PA 1IBKD 4GKJD 1XNRD 4DR3D 4NXMD 1DM9A 3T1YD 5IWAD 4DR6D 3OTOD 4DV6D 4OX9D 4DV3D 1XMQD 4LFAD 4YHHD 4JI1D 3T1HD 4B3SD 4B3TD 4OUDA 1IBMD 2F4VD 4DV4D 4DR5D 1IBLD 4LF6D 1FJGD 4DV2D 4X62D 2UUAD 4LF5D 2UUBD 4DR7D 2ZM6D 4JI4D 4LF8D 3DH3A 1KSVA 2ISTA 1JH3A 1XNQD 1VIOA 1HNZD 4JI5D 3KBGA 4B3RD 1N36D 2UXBD 4B3MD 1FKAD 1H3EA 1C05A 2E5LD 4JI8D 2VQFD 4DV7D 2VQED 4AQYD 4LGTA 2KTLA 4DR1D 4JYAD 1N32D 2UU9D 1KSLA 2UXDD 1H3FA 4DUYD 1I94D 4LF4D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LMN D;  1C06 A;  1KSK A;  4DV5 D;  4X66 D;  4X64 D;  4JI6 D;  2JAN A;  4DV0 D;  4JI7 D;  5LMU D;  4DUZ D;  1N34 D;  2UXC D;  4DV1 D;  1HNW D;  4JV5 D;  4LFB D;  4GKK D;  4LFC D;  4DR4 D;  1J5E D;  1P9K A;  4X65 D;  2UUC D;  4NXN D;  1HR0 D;  5BR8 D;  4JI2 D;  4KHP D;  3HP7 A;  4JI3 D;  4JI0 D;  4K0K D;  1HNX D;  4DR2 D;  2HHH D;  4LF7 D;  4YY3 D;  1N33 D;  1XMO D;  4LF9 D;  2K6P A;  1IBK D;  4GKJ D;  1XNR D;  4DR3 D;  4NXM D;  1DM9 A;  3T1Y D;  5IWA D;  4DR6 D;  3OTO D;  4DV6 D;  4OX9 D;  4DV3 D;  1XMQ D;  4LFA D;  4YHH D;  4JI1 D;  3T1H D;  4B3S D;  4B3T D;  4OUD A;  1IBM D;  2F4V D;  4DV4 D;  4DR5 D;  1IBL D;  4LF6 D;  1FJG D;  4DV2 D;  4X62 D;  2UUA D;  4LF5 D;  2UUB D;  4DR7 D;  2ZM6 D;  4JI4 D;  4LF8 D;  3DH3 A;  1KSV A;  2IST A;  1JH3 A;  1XNQ D;  1VIO A;  1HNZ D;  4JI5 D;  3KBG A;  4B3R D;  1N36 D;  2UXB D;  4B3M D;  1FKA D;  1H3E A;  1C05 A;  2E5L D;  4JI8 D;  2VQF D;  4DV7 D;  2VQE D;  4AQY D;  4LGT A;  2KTL A;  4DR1 D;  4JYA D;  1N32 D;  2UU9 D;  1KSL A;  2UXD D;  1H3F A;  4DUY D;  1I94 D;  4LF4 D; 
#chains in the Genus database with same CATH topology
 5LMN D;  1C06 A;  1KSK A;  4DV5 D;  3ONG A;  4X66 D;  3FN1 A;  2I1S A;  4X64 D;  4JI6 D;  2JAN A;  4NNJ A;  4DV0 D;  4JI7 D;  5LMU D;  4DUZ D;  1N34 D;  3ONH A;  2UXC D;  4DV1 D;  1Y8X B;  2ZTB A;  3KYC B;  1HNW D;  4JV5 D;  4LFB D;  4W5V B;  4GKK D;  4LFC D;  4DR4 D;  1J5E D;  1P9K A;  4X65 D;  4II2 A;  5A2Q E;  1Y8Q B;  2UUC D;  4NXN D;  1HR0 D;  5BR8 D;  4JI2 D;  4KHP D;  3HP7 A;  4JI3 D;  4JI0 D;  4K0K D;  1HNX D;  4DR2 D;  3KYD B;  2HHH D;  3J80 E;  2L3N A;  4LF7 D;  4YY3 D;  1N33 D;  1XMO D;  4LF9 D;  2K6P A;  1IBK D;  4GKJ D;  1XNR D;  3J7A F;  4DR3 D;  4NXM D;  1DM9 A;  3T1Y D;  5IWA D;  4DR6 D;  5FLX E;  3OTO D;  4DV6 D;  4OX9 D;  4DV3 D;  1XMQ D;  4LFA D;  5LL6 S;  4II3 A;  4YHH D;  4JI1 D;  3T1H D;  4B3S D;  4B3T D;  4OUD A;  3CMM A;  1IBM D;  3J81 E;  2F4V D;  4DV4 D;  4DR5 D;  1IBL D;  4LF6 D;  5FQ2 B;  5KNL A;  5IT9 E;  2LQ7 A;  1FJG D;  4DV2 D;  2NVU B;  4X62 D;  2UUA D;  4LF5 D;  2UUB D;  4DR7 D;  2ZM6 D;  4JI4 D;  4LF8 D;  3DH3 A;  3JAM E;  1KSV A;  2IST A;  1JH3 A;  1XNQ D;  1VIO A;  1HNZ D;  4JI5 D;  3KBG A;  4B3R D;  1N36 D;  2UXB D;  4B3M D;  1FKA D;  1H3E A;  1C05 A;  2E5L D;  4JI8 D;  2VQF D;  4DV7 D;  2VQE D;  4AQY D;  4LGT A;  2KTL A;  4DR1 D;  4JYA D;  1N32 D;  2UU9 D;  1KSL A;  2UXD D;  1Y8R B;  1H3F A;  4DUY D;  1I94 D;  4LF4 D; 
#chains in the Genus database with same CATH homology
 5LMN D;  1C06 A;  1KSK A;  4DV5 D;  4X66 D;  4X64 D;  4JI6 D;  2JAN A;  4DV0 D;  4JI7 D;  5LMU D;  4DUZ D;  1N34 D;  2UXC D;  4DV1 D;  1HNW D;  4JV5 D;  4LFB D;  4GKK D;  4LFC D;  4DR4 D;  1J5E D;  1P9K A;  4X65 D;  2UUC D;  4NXN D;  1HR0 D;  5BR8 D;  4JI2 D;  4KHP D;  3HP7 A;  4JI3 D;  4JI0 D;  4K0K D;  1HNX D;  4DR2 D;  2HHH D;  2L3N A;  4LF7 D;  4YY3 D;  1N33 D;  1XMO D;  4LF9 D;  2K6P A;  1IBK D;  4GKJ D;  1XNR D;  4DR3 D;  4NXM D;  1DM9 A;  3T1Y D;  5IWA D;  4DR6 D;  3OTO D;  4DV6 D;  4OX9 D;  4DV3 D;  1XMQ D;  4LFA D;  4YHH D;  4JI1 D;  3T1H D;  4B3S D;  4B3T D;  4OUD A;  1IBM D;  2F4V D;  4DV4 D;  4DR5 D;  1IBL D;  4LF6 D;  1FJG D;  4DV2 D;  4X62 D;  2UUA D;  4LF5 D;  2UUB D;  4DR7 D;  2ZM6 D;  4JI4 D;  4LF8 D;  3DH3 A;  1KSV A;  2IST A;  1JH3 A;  1XNQ D;  1VIO A;  1HNZ D;  4JI5 D;  3KBG A;  4B3R D;  1N36 D;  2UXB D;  4B3M D;  1FKA D;  1H3E A;  1C05 A;  2E5L D;  4JI8 D;  2VQF D;  4DV7 D;  2VQE D;  4AQY D;  4LGT A;  2KTL A;  4DR1 D;  4JYA D;  1N32 D;  2UU9 D;  1KSL A;  2UXD D;  1H3F A;  4DUY D;  1I94 D;  4LF4 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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