4AQYD

Structure of ribosome-apramycin complexes
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
208
structure length
208
Chain Sequence
GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 16S RIBOSOMAL RNA
total genus 52
structure length 208
sequence length 208
ec nomenclature
pdb deposition date 2012-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00163 Ribosomal_S4 Ribosomal protein S4/S9 N-terminal domain
D PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1050.10 Mainly Alpha Orthogonal Bundle Ribosomal Protein S4 Delta 41; Chain A, domain 1 Ribosomal Protein S4 Delta 41; Chain A, domain 1 4aqyD01
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 4aqyD02
2UXCD 4JI5D 2UUAD 1IBMD 4OX9D 1VIOA 4LF6D 1HNWD 4JYAD 4DV5D 4KHPD 1HNZD 3DH3A 2HHHD 4DV3D 4NXMD 1XMQD 4DR2D 5LMND 4DR7D 1IBKD 4DR6D 4GKKD 4OUDA 4JV5D 1C05A 4LF9D 1FJGD 4LFAD 4DV4D 5LMUD 1FKAD 4JI7D 2ISTA 1N32D 4LFBD 1N36D 3HP7A 2ZM6D 2KTLA 4JI2D 5BR8D 1JH3A 4DV1D 1I94D 4JI8D 2F4VD 1KSLA 1J5ED 4DV0D 2UU9D 1H3FA 4DV2D 4B3SD 3T1HD 4DUZD 1N33D 3KBGA 1HNXD 4LF8D 1N34D 5IWAD 4YY3D 1P9KA 2UXBD 4JI3D 4YHHD 4JI6D 3OTOD 2UUBD 2UXDD 4GKJD 4X65D 4B3MD 1HR0D 4B3TD 4B3RD 4LF7D 1KSVA 1XNQD 4LFCD 1XMOD 4LGTA 4DR5D 1DM9A 4AQYD 2JANA 4LF5D 2E5LD 1H3EA 2VQED 4DV6D 4JI0D 3T1YD 2K6PA 4DR1D 4JI4D 4NXND 4JI1D 1C06A 4LF4D 4DUYD 4X62D 1IBLD 4DR3D 2UUCD 1XNRD 4DV7D 4X66D 1KSKA 4K0KD 4X64D 4DR4D 2VQFD
chains in the Genus database with same CATH superfamily
2UXCD 4JI5D 2UUAD 1IBMD 4OX9D 1VIOA 4LF6D 1HNWD 3J7AF 4JYAD 5FLXE 4DV5D 2ZTBA 4KHPD 1HNZD 4II2A 3DH3A 2HHHD 4DV3D 4NXMD 1XMQD 4DR2D 5LMND 4W5VB 4DR7D 1IBKD 4DR6D 4GKKD 4OUDA 4JV5D 1C05A 4LF9D 5FQ2B 1FJGD 4LFAD 4DV4D 5LMUD 1FKAD 4JI7D 2ISTA 1N32D 4LFBD 1N36D 3HP7A 2ZM6D 2KTLA 4JI2D 5BR8D 1JH3A 5LL6S 4DV1D 3ONGA 1I94D 4JI8D 2F4VD 1KSLA 1J5ED 4DV0D 2UU9D 3FN1A 1H3FA 4DV2D 4B3SD 3T1HD 5IT9E 4DUZD 1N33D 1Y8QB 3KBGA 3J81E 2I1SA 1HNXD 4LF8D 1N34D 5IWAD 4YY3D 1P9KA 2UXBD 4JI3D 2L3NA 4YHHD 4JI6D 3OTOD 2UUBD 4II3A 2UXDD 4GKJD 4X65D 4B3MD 1HR0D 3KYCB 5A2QE 4B3TD 4B3RD 4LF7D 1KSVA 1XNQD 4LFCD 1XMOD 4LGTA 4NNJA 1Y8RB 4DR5D 1DM9A 4AQYD 1Y8XB 2LQ7A 2NVUB 2JANA 4LF5D 2E5LD 1H3EA 2VQED 4DV6D 3JAME 4JI0D 3T1YD 2K6PA 4DR1D 4JI4D 4NXND 4JI1D 1C06A 4LF4D 4DUYD 5KNLA 3CMMA 4X62D 1IBLD 3KYDB 4DR3D 3ONHA 2UUCD 1XNRD 4DV7D 4X66D 1KSKA 4K0KD 3J80E 4X64D 4DR4D 2VQFD
chains in the Genus database with same CATH topology
2UXCD 4JI5D 2UUAD 1IBMD 4OX9D 1VIOA 4LF6D 1HNWD 4JYAD 4DV5D 4KHPD 1HNZD 3DH3A 2HHHD 4DV3D 4NXMD 1XMQD 4DR2D 5LMND 4DR7D 1IBKD 4DR6D 4GKKD 4OUDA 4JV5D 1C05A 4LF9D 1FJGD 4LFAD 4DV4D 5LMUD 1FKAD 4JI7D 2ISTA 1N32D 4LFBD 1N36D 3HP7A 2ZM6D 2KTLA 4JI2D 5BR8D 1JH3A 4DV1D 1I94D 4JI8D 2F4VD 1KSLA 1J5ED 4DV0D 2UU9D 1H3FA 4DV2D 4B3SD 3T1HD 4DUZD 1N33D 3KBGA 1HNXD 4LF8D 1N34D 5IWAD 4YY3D 1P9KA 2UXBD 4JI3D 2L3NA 4YHHD 4JI6D 3OTOD 2UUBD 2UXDD 4GKJD 4X65D 4B3MD 1HR0D 4B3TD 4B3RD 4LF7D 1KSVA 1XNQD 4LFCD 1XMOD 4LGTA 4DR5D 1DM9A 4AQYD 2JANA 4LF5D 2E5LD 1H3EA 2VQED 4DV6D 4JI0D 3T1YD 2K6PA 4DR1D 4JI4D 4NXND 4JI1D 1C06A 4LF4D 4DUYD 4X62D 1IBLD 4DR3D 2UUCD 1XNRD 4DV7D 4X66D 1KSKA 4K0KD 4X64D 4DR4D 2VQFD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2UXC D;  4JI5 D;  2UUA D;  1IBM D;  4OX9 D;  1VIO A;  4LF6 D;  1HNW D;  4JYA D;  4DV5 D;  4KHP D;  1HNZ D;  3DH3 A;  2HHH D;  4DV3 D;  4NXM D;  1XMQ D;  4DR2 D;  5LMN D;  4DR7 D;  1IBK D;  4DR6 D;  4GKK D;  4OUD A;  4JV5 D;  1C05 A;  4LF9 D;  1FJG D;  4LFA D;  4DV4 D;  5LMU D;  1FKA D;  4JI7 D;  2IST A;  1N32 D;  4LFB D;  1N36 D;  3HP7 A;  2ZM6 D;  2KTL A;  4JI2 D;  5BR8 D;  1JH3 A;  4DV1 D;  1I94 D;  4JI8 D;  2F4V D;  1KSL A;  1J5E D;  4DV0 D;  2UU9 D;  1H3F A;  4DV2 D;  4B3S D;  3T1H D;  4DUZ D;  1N33 D;  3KBG A;  1HNX D;  4LF8 D;  1N34 D;  5IWA D;  4YY3 D;  1P9K A;  2UXB D;  4JI3 D;  4YHH D;  4JI6 D;  3OTO D;  2UUB D;  2UXD D;  4GKJ D;  4X65 D;  4B3M D;  1HR0 D;  4B3T D;  4B3R D;  4LF7 D;  1KSV A;  1XNQ D;  4LFC D;  1XMO D;  4LGT A;  4DR5 D;  1DM9 A;  4AQY D;  2JAN A;  4LF5 D;  2E5L D;  1H3E A;  2VQE D;  4DV6 D;  4JI0 D;  3T1Y D;  2K6P A;  4DR1 D;  4JI4 D;  4NXN D;  4JI1 D;  1C06 A;  4LF4 D;  4DUY D;  4X62 D;  1IBL D;  4DR3 D;  2UUC D;  1XNR D;  4DV7 D;  4X66 D;  1KSK A;  4K0K D;  4X64 D;  4DR4 D;  2VQF D; 
#chains in the Genus database with same CATH topology
 2UXC D;  4JI5 D;  2UUA D;  1IBM D;  4OX9 D;  1VIO A;  4LF6 D;  1HNW D;  3J7A F;  4JYA D;  5FLX E;  4DV5 D;  2ZTB A;  4KHP D;  1HNZ D;  4II2 A;  3DH3 A;  2HHH D;  4DV3 D;  4NXM D;  1XMQ D;  4DR2 D;  5LMN D;  4W5V B;  4DR7 D;  1IBK D;  4DR6 D;  4GKK D;  4OUD A;  4JV5 D;  1C05 A;  4LF9 D;  5FQ2 B;  1FJG D;  4LFA D;  4DV4 D;  5LMU D;  1FKA D;  4JI7 D;  2IST A;  1N32 D;  4LFB D;  1N36 D;  3HP7 A;  2ZM6 D;  2KTL A;  4JI2 D;  5BR8 D;  1JH3 A;  5LL6 S;  4DV1 D;  3ONG A;  1I94 D;  4JI8 D;  2F4V D;  1KSL A;  1J5E D;  4DV0 D;  2UU9 D;  3FN1 A;  1H3F A;  4DV2 D;  4B3S D;  3T1H D;  5IT9 E;  4DUZ D;  1N33 D;  1Y8Q B;  3KBG A;  3J81 E;  2I1S A;  1HNX D;  4LF8 D;  1N34 D;  5IWA D;  4YY3 D;  1P9K A;  2UXB D;  4JI3 D;  2L3N A;  4YHH D;  4JI6 D;  3OTO D;  2UUB D;  4II3 A;  2UXD D;  4GKJ D;  4X65 D;  4B3M D;  1HR0 D;  3KYC B;  5A2Q E;  4B3T D;  4B3R D;  4LF7 D;  1KSV A;  1XNQ D;  4LFC D;  1XMO D;  4LGT A;  4NNJ A;  1Y8R B;  4DR5 D;  1DM9 A;  4AQY D;  1Y8X B;  2LQ7 A;  2NVU B;  2JAN A;  4LF5 D;  2E5L D;  1H3E A;  2VQE D;  4DV6 D;  3JAM E;  4JI0 D;  3T1Y D;  2K6P A;  4DR1 D;  4JI4 D;  4NXN D;  4JI1 D;  1C06 A;  4LF4 D;  4DUY D;  5KNL A;  3CMM A;  4X62 D;  1IBL D;  3KYD B;  4DR3 D;  3ONH A;  2UUC D;  1XNR D;  4DV7 D;  4X66 D;  1KSK A;  4K0K D;  3J80 E;  4X64 D;  4DR4 D;  2VQF D; 
#chains in the Genus database with same CATH homology
 2UXC D;  4JI5 D;  2UUA D;  1IBM D;  4OX9 D;  1VIO A;  4LF6 D;  1HNW D;  4JYA D;  4DV5 D;  4KHP D;  1HNZ D;  3DH3 A;  2HHH D;  4DV3 D;  4NXM D;  1XMQ D;  4DR2 D;  5LMN D;  4DR7 D;  1IBK D;  4DR6 D;  4GKK D;  4OUD A;  4JV5 D;  1C05 A;  4LF9 D;  1FJG D;  4LFA D;  4DV4 D;  5LMU D;  1FKA D;  4JI7 D;  2IST A;  1N32 D;  4LFB D;  1N36 D;  3HP7 A;  2ZM6 D;  2KTL A;  4JI2 D;  5BR8 D;  1JH3 A;  4DV1 D;  1I94 D;  4JI8 D;  2F4V D;  1KSL A;  1J5E D;  4DV0 D;  2UU9 D;  1H3F A;  4DV2 D;  4B3S D;  3T1H D;  4DUZ D;  1N33 D;  3KBG A;  1HNX D;  4LF8 D;  1N34 D;  5IWA D;  4YY3 D;  1P9K A;  2UXB D;  4JI3 D;  2L3N A;  4YHH D;  4JI6 D;  3OTO D;  2UUB D;  2UXD D;  4GKJ D;  4X65 D;  4B3M D;  1HR0 D;  4B3T D;  4B3R D;  4LF7 D;  1KSV A;  1XNQ D;  4LFC D;  1XMO D;  4LGT A;  4DR5 D;  1DM9 A;  4AQY D;  2JAN A;  4LF5 D;  2E5L D;  1H3E A;  2VQE D;  4DV6 D;  4JI0 D;  3T1Y D;  2K6P A;  4DR1 D;  4JI4 D;  4NXN D;  4JI1 D;  1C06 A;  4LF4 D;  4DUY D;  4X62 D;  1IBL D;  4DR3 D;  2UUC D;  1XNR D;  4DV7 D;  4X66 D;  1KSK A;  4K0K D;  4X64 D;  4DR4 D;  2VQF D; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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