4DR7D

Crystal structure of the thermus thermophilus (hb8) 30s ribosomal subunit with codon, crystallographically disordered near-cognate transfer rna anticodon stem-loop mismatched at the second codon position, and streptomycin bound
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
208
structure length
208
Chain Sequence
GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A structural basis for streptomycin-induced misreading of the genetic code.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 16S rRNA
total genus 54
structure length 208
sequence length 208
ec nomenclature
pdb deposition date 2012-02-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00163 Ribosomal_S4 Ribosomal protein S4/S9 N-terminal domain
D PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1050.10 Mainly Alpha Orthogonal Bundle Ribosomal Protein S4 Delta 41; Chain A, domain 1 Ribosomal Protein S4 Delta 41; Chain A, domain 1 4dr7D01
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 4dr7D02
4DR3D 2K6PA 1IBMD 2VQED 4NXND 1XNQD 5IWAD 4AQYD 2UUCD 4JI3D 4DR1D 2ISTA 1XMQD 2KTLA 4K0KD 1C05A 1IBLD 1XNRD 2UXCD 1I94D 4GKKD 2UUAD 4JV5D 1C06A 4X66D 1IBKD 4DV3D 4LF7D 4LGTA 4LFAD 4LF4D 1KSVA 4X65D 4DR5D 4JI5D 4DV6D 1HNZD 1FJGD 4DV5D 4KHPD 4DV7D 1HNXD 2UU9D 4B3RD 4B3MD 1N32D 1H3FA 3HP7A 2UXDD 4X64D 2UXBD 4YHHD 2UUBD 1XMOD 4OUDA 1KSKA 3OTOD 5BR8D 4JI8D 4DUYD 1P9KA 1JH3A 3DH3A 4B3SD 4DV1D 2E5LD 4LF6D 4DV0D 4DV2D 4JI6D 4NXMD 1H3EA 1N36D 4DR2D 1DM9A 4DR4D 1HR0D 1N33D 4B3TD 3T1HD 4JI4D 4GKJD 2VQFD 4JI2D 2HHHD 1KSLA 1FKAD 3KBGA 4X62D 4LFCD 5LMUD 4DR7D 4YY3D 1N34D 4LFBD 4JI7D 2JANA 4DR6D 4JYAD 1HNWD 4JI0D 1J5ED 1VIOA 5LMND 4LF5D 3T1YD 4DV4D 4OX9D 2ZM6D 2F4VD 4LF8D 4DUZD 4LF9D 4JI1D
chains in the Genus database with same CATH superfamily
4DR3D 3ONHA 2K6PA 1IBMD 2VQED 4NXND 1XNQD 5IWAD 4AQYD 2UUCD 4JI3D 4DR1D 2ISTA 4II2A 1XMQD 2L3NA 2KTLA 4K0KD 2I1SA 1C05A 1IBLD 1XNRD 2UXCD 1I94D 4GKKD 2UUAD 3ONGA 4JV5D 1C06A 1Y8QB 4X66D 1IBKD 4DV3D 4LF7D 4LGTA 4LFAD 2ZTBA 4LF4D 1KSVA 4X65D 4DR5D 4JI5D 4DV6D 1HNZD 1FJGD 4W5VB 4DV5D 4KHPD 4II3A 4DV7D 1HNXD 2UU9D 4B3RD 4B3MD 1N32D 1H3FA 2LQ7A 3HP7A 2UXDD 4X64D 2UXBD 4YHHD 3KYCB 2UUBD 1XMOD 1Y8XB 5IT9E 5FLXE 4OUDA 1KSKA 5LL6S 2NVUB 3OTOD 5BR8D 4JI8D 4DUYD 1P9KA 3FN1A 1JH3A 3DH3A 5FQ2B 3J7AF 4B3SD 4DV1D 3J81E 2E5LD 4LF6D 4DV0D 4DV2D 4JI6D 4NXMD 1H3EA 1N36D 4DR2D 1DM9A 3J80E 4DR4D 1HR0D 1N33D 4B3TD 3T1HD 4JI4D 4GKJD 3JAME 2VQFD 4JI2D 2HHHD 1KSLA 1FKAD 3KBGA 4X62D 5A2QE 4NNJA 4LFCD 5LMUD 4DR7D 4YY3D 1N34D 4LFBD 4JI7D 2JANA 4DR6D 4JYAD 1HNWD 4JI0D 1J5ED 1VIOA 5LMND 3CMMA 4LF5D 3T1YD 3KYDB 4DV4D 4OX9D 2ZM6D 2F4VD 4LF8D 5KNLA 1Y8RB 4DUZD 4LF9D 4JI1D
chains in the Genus database with same CATH topology
4DR3D 2K6PA 1IBMD 2VQED 4NXND 1XNQD 5IWAD 4AQYD 2UUCD 4JI3D 4DR1D 2ISTA 1XMQD 2L3NA 2KTLA 4K0KD 1C05A 1IBLD 1XNRD 2UXCD 1I94D 4GKKD 2UUAD 4JV5D 1C06A 4X66D 1IBKD 4DV3D 4LF7D 4LGTA 4LFAD 4LF4D 1KSVA 4X65D 4DR5D 4JI5D 4DV6D 1HNZD 1FJGD 4DV5D 4KHPD 4DV7D 1HNXD 2UU9D 4B3RD 4B3MD 1N32D 1H3FA 3HP7A 2UXDD 4X64D 2UXBD 4YHHD 2UUBD 1XMOD 4OUDA 1KSKA 3OTOD 5BR8D 4JI8D 4DUYD 1P9KA 1JH3A 3DH3A 4B3SD 4DV1D 2E5LD 4LF6D 4DV0D 4DV2D 4JI6D 4NXMD 1H3EA 1N36D 4DR2D 1DM9A 4DR4D 1HR0D 1N33D 4B3TD 3T1HD 4JI4D 4GKJD 2VQFD 4JI2D 2HHHD 1KSLA 1FKAD 3KBGA 4X62D 4LFCD 5LMUD 4DR7D 4YY3D 1N34D 4LFBD 4JI7D 2JANA 4DR6D 4JYAD 1HNWD 4JI0D 1J5ED 1VIOA 5LMND 4LF5D 3T1YD 4DV4D 4OX9D 2ZM6D 2F4VD 4LF8D 4DUZD 4LF9D 4JI1D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DR3 D;  2K6P A;  1IBM D;  2VQE D;  4NXN D;  1XNQ D;  5IWA D;  4AQY D;  2UUC D;  4JI3 D;  4DR1 D;  2IST A;  1XMQ D;  2KTL A;  4K0K D;  1C05 A;  1IBL D;  1XNR D;  2UXC D;  1I94 D;  4GKK D;  2UUA D;  4JV5 D;  1C06 A;  4X66 D;  1IBK D;  4DV3 D;  4LF7 D;  4LGT A;  4LFA D;  4LF4 D;  1KSV A;  4X65 D;  4DR5 D;  4JI5 D;  4DV6 D;  1HNZ D;  1FJG D;  4DV5 D;  4KHP D;  4DV7 D;  1HNX D;  2UU9 D;  4B3R D;  4B3M D;  1N32 D;  1H3F A;  3HP7 A;  2UXD D;  4X64 D;  2UXB D;  4YHH D;  2UUB D;  1XMO D;  4OUD A;  1KSK A;  3OTO D;  5BR8 D;  4JI8 D;  4DUY D;  1P9K A;  1JH3 A;  3DH3 A;  4B3S D;  4DV1 D;  2E5L D;  4LF6 D;  4DV0 D;  4DV2 D;  4JI6 D;  4NXM D;  1H3E A;  1N36 D;  4DR2 D;  1DM9 A;  4DR4 D;  1HR0 D;  1N33 D;  4B3T D;  3T1H D;  4JI4 D;  4GKJ D;  2VQF D;  4JI2 D;  2HHH D;  1KSL A;  1FKA D;  3KBG A;  4X62 D;  4LFC D;  5LMU D;  4DR7 D;  4YY3 D;  1N34 D;  4LFB D;  4JI7 D;  2JAN A;  4DR6 D;  4JYA D;  1HNW D;  4JI0 D;  1J5E D;  1VIO A;  5LMN D;  4LF5 D;  3T1Y D;  4DV4 D;  4OX9 D;  2ZM6 D;  2F4V D;  4LF8 D;  4DUZ D;  4LF9 D;  4JI1 D; 
#chains in the Genus database with same CATH topology
 4DR3 D;  3ONH A;  2K6P A;  1IBM D;  2VQE D;  4NXN D;  1XNQ D;  5IWA D;  4AQY D;  2UUC D;  4JI3 D;  4DR1 D;  2IST A;  4II2 A;  1XMQ D;  2L3N A;  2KTL A;  4K0K D;  2I1S A;  1C05 A;  1IBL D;  1XNR D;  2UXC D;  1I94 D;  4GKK D;  2UUA D;  3ONG A;  4JV5 D;  1C06 A;  1Y8Q B;  4X66 D;  1IBK D;  4DV3 D;  4LF7 D;  4LGT A;  4LFA D;  2ZTB A;  4LF4 D;  1KSV A;  4X65 D;  4DR5 D;  4JI5 D;  4DV6 D;  1HNZ D;  1FJG D;  4W5V B;  4DV5 D;  4KHP D;  4II3 A;  4DV7 D;  1HNX D;  2UU9 D;  4B3R D;  4B3M D;  1N32 D;  1H3F A;  2LQ7 A;  3HP7 A;  2UXD D;  4X64 D;  2UXB D;  4YHH D;  3KYC B;  2UUB D;  1XMO D;  1Y8X B;  5IT9 E;  5FLX E;  4OUD A;  1KSK A;  5LL6 S;  2NVU B;  3OTO D;  5BR8 D;  4JI8 D;  4DUY D;  1P9K A;  3FN1 A;  1JH3 A;  3DH3 A;  5FQ2 B;  3J7A F;  4B3S D;  4DV1 D;  3J81 E;  2E5L D;  4LF6 D;  4DV0 D;  4DV2 D;  4JI6 D;  4NXM D;  1H3E A;  1N36 D;  4DR2 D;  1DM9 A;  3J80 E;  4DR4 D;  1HR0 D;  1N33 D;  4B3T D;  3T1H D;  4JI4 D;  4GKJ D;  3JAM E;  2VQF D;  4JI2 D;  2HHH D;  1KSL A;  1FKA D;  3KBG A;  4X62 D;  5A2Q E;  4NNJ A;  4LFC D;  5LMU D;  4DR7 D;  4YY3 D;  1N34 D;  4LFB D;  4JI7 D;  2JAN A;  4DR6 D;  4JYA D;  1HNW D;  4JI0 D;  1J5E D;  1VIO A;  5LMN D;  3CMM A;  4LF5 D;  3T1Y D;  3KYD B;  4DV4 D;  4OX9 D;  2ZM6 D;  2F4V D;  4LF8 D;  5KNL A;  1Y8R B;  4DUZ D;  4LF9 D;  4JI1 D; 
#chains in the Genus database with same CATH homology
 4DR3 D;  2K6P A;  1IBM D;  2VQE D;  4NXN D;  1XNQ D;  5IWA D;  4AQY D;  2UUC D;  4JI3 D;  4DR1 D;  2IST A;  1XMQ D;  2L3N A;  2KTL A;  4K0K D;  1C05 A;  1IBL D;  1XNR D;  2UXC D;  1I94 D;  4GKK D;  2UUA D;  4JV5 D;  1C06 A;  4X66 D;  1IBK D;  4DV3 D;  4LF7 D;  4LGT A;  4LFA D;  4LF4 D;  1KSV A;  4X65 D;  4DR5 D;  4JI5 D;  4DV6 D;  1HNZ D;  1FJG D;  4DV5 D;  4KHP D;  4DV7 D;  1HNX D;  2UU9 D;  4B3R D;  4B3M D;  1N32 D;  1H3F A;  3HP7 A;  2UXD D;  4X64 D;  2UXB D;  4YHH D;  2UUB D;  1XMO D;  4OUD A;  1KSK A;  3OTO D;  5BR8 D;  4JI8 D;  4DUY D;  1P9K A;  1JH3 A;  3DH3 A;  4B3S D;  4DV1 D;  2E5L D;  4LF6 D;  4DV0 D;  4DV2 D;  4JI6 D;  4NXM D;  1H3E A;  1N36 D;  4DR2 D;  1DM9 A;  4DR4 D;  1HR0 D;  1N33 D;  4B3T D;  3T1H D;  4JI4 D;  4GKJ D;  2VQF D;  4JI2 D;  2HHH D;  1KSL A;  1FKA D;  3KBG A;  4X62 D;  4LFC D;  5LMU D;  4DR7 D;  4YY3 D;  1N34 D;  4LFB D;  4JI7 D;  2JAN A;  4DR6 D;  4JYA D;  1HNW D;  4JI0 D;  1J5E D;  1VIO A;  5LMN D;  4LF5 D;  3T1Y D;  4DV4 D;  4OX9 D;  2ZM6 D;  2F4V D;  4LF8 D;  4DUZ D;  4LF9 D;  4JI1 D; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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