1AJA | Genus

Total Genus 158

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	158
Knots found	KnotProt 2.0: S +3₁
sequence length	449
structure length	435
Chain Sequence	TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQGATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAEARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Non specific mono-esterase
source organism	Escherichia coli
publication title	Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase. pubmed doi rcsb
molecule keywords	ALKALINE PHOSPHATASE
total genus	158
structure length	435
sequence length	449
chains with identical sequence	B
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	1995-08-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1ajaA00

3DPCA 4TN0A 4LRDA 5C66A 3MK1A 4UOPA 4LR9A 3NKQA 3M7VA 5DLTA 2GA3A 5GRRA 3E2DA 4FDJA 1ZEFA 4GTXA 5IJSA 3BDFA 5AJ9A 3UN2A 1K7HA 1KHJA 2D1GA 2VQRA 5DLWA 4LREA 4CYSA 4CXKA 1ALJA 3CMRA 5TJ3A 1EW8A 4GTYA 4LQYA 5IJQA 3T01A 2W5VA 1O99A 4QAXA 4LR8A 3UO0A 1SHNA 3NKRA 3NKPA 3KD8A 2W8SA 1SHQA 4LR2A 1URAA 3UN3A 3OT9A 2W8DA 2QZUA 5LIAA 2ANHA 3UN5A 1O98A 2W5QA 1EW2A 1HJKA 5K4PA 2X98A 1ELZA 2GLQA 4UPHA 4LRAA 4MIVA 2W5XA 4CXUA 5L0BA 1Y7AA 1B8JA 3NKMA 4ZG6A 3WAWA 2W5RA 3BDHA 3Q3QA 3LXQA 3MK0A 1N2KA 3BDGB 1AJDA 2GSNA 2ZKTA 3M8ZA 3UNYA 3WBHA 4KAYA 2GSOA 5LQQA 5L0EA 1AJAA 3ED4A 3M8YA 4KJGA 4UPKA 1Y6VA 1EW9A 3T02A 3WAVA 1E33P 1E3CP 1E1ZP 2XR9A 5LRNA 3TWZA 1KHLA 5KXAA 4KJDA 3NVLA 3NKNA 2W5WA 1KHKA 3DYCA 4MHXA 1KH7A 1ZEDA 3WAXA 1KH4A 5DLVA 1N2LA 1ANIA 2G9YA 2RH6A 4CYRA 1ZEBA 1ELYA 1KHNA 1EI6A 4LR7A 5HRTA 4GTZA 5LRMA 1FSUA 3NKOA 4MY4A 4LRBA 3M8WA 4UPIA 5EGEA 1ALKA 1HQAA 3T00A 3B5QA 4NWJA 4ZG9A 3IDDA 4GTWA 4FDIA 4CXSA 1ELXA 2IUCB 4N7TA 1AJBA 2IFYA 5L0KA 1ALIA 3BDGA 4LRFA 4UPLA 3IGZB 5GOVA 1P49A 4UORA 1KH5A 4NWXA 1ED8A 3WAYA 4UOOA 1HDHA 3A52A 3IGYB 1AJCA 4LRCA 4B56A 4ZGAA 3TX0A 2W5SA 4KAVA 1EJJA 4YR1A 1ALHA 1E2SP 3SZYA 1KH9A 2W5TA 1EQJA 3TG0A 2IUCA 5EGHA 5INHA 3MK2A 2XRGA 4ZG7A 3SZZA 1ANJA 1ED9A 1URBA 1AUKA 4KM4A 2GSUA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3DPC A;  4TN0 A;  4LRD A;  5C66 A;  3MK1 A;  4UOP A;  4LR9 A;  3NKQ A;  3M7V A;  5DLT A;  2GA3 A;  5GRR A;  3E2D A;  4FDJ A;  1ZEF A;  4GTX A;  5IJS A;  3BDF A;  5AJ9 A;  3UN2 A;  1K7H A;  1KHJ A;  2D1G A;  2VQR A;  5DLW A;  4LRE A;  4CYS A;  4CXK A;  1ALJ A;  3CMR A;  5TJ3 A;  1EW8 A;  4GTY A;  4LQY A;  5IJQ A;  3T01 A;  2W5V A;  1O99 A;  4QAX A;  4LR8 A;  3UO0 A;  1SHN A;  3NKR A;  3NKP A;  3KD8 A;  2W8S A;  1SHQ A;  4LR2 A;  1URA A;  3UN3 A;  3OT9 A;  2W8D A;  2QZU A;  5LIA A;  2ANH A;  3UN5 A;  1O98 A;  2W5Q A;  1EW2 A;  1HJK A;  5K4P A;  2X98 A;  1ELZ A;  2GLQ A;  4UPH A;  4LRA A;  4MIV A;  2W5X A;  4CXU A;  5L0B A;  1Y7A A;  1B8J A;  3NKM A;  4ZG6 A;  3WAW A;  2W5R A;  3BDH A;  3Q3Q A;  3LXQ A;  3MK0 A;  1N2K A;  3BDG B;  1AJD A;  2GSN A;  2ZKT A;  3M8Z A;  3UNY A;  3WBH A;  4KAY A;  2GSO A;  5LQQ A;  5L0E A;  1AJA A;  3ED4 A;  3M8Y A;  4KJG A;  4UPK A;  1Y6V A;  1EW9 A;  3T02 A;  3WAV A;  1E33 P;  1E3C P;  1E1Z P;  2XR9 A;  5LRN A;  3TWZ A;  1KHL A;  5KXA A;  4KJD A;  3NVL A;  3NKN A;  2W5W A;  1KHK A;  3DYC A;  4MHX A;  1KH7 A;  1ZED A;  3WAX A;  1KH4 A;  5DLV A;  1N2L A;  1ANI A;  2G9Y A;  2RH6 A;  4CYR A;  1ZEB A;  1ELY A;  1KHN A;  1EI6 A;  4LR7 A;  5HRT A;  4GTZ A;  5LRM A;  1FSU A;  3NKO A;  4MY4 A;  4LRB A;  3M8W A;  4UPI A;  5EGE A;  1ALK A;  1HQA A;  3T00 A;  3B5Q A;  4NWJ A;  4ZG9 A;  3IDD A;  4GTW A;  4FDI A;  4CXS A;  1ELX A;  2IUC B;  4N7T A;  1AJB A;  2IFY A;  5L0K A;  1ALI A;  3BDG A;  4LRF A;  4UPL A;  3IGZ B;  5GOV A;  1P49 A;  4UOR A;  1KH5 A;  4NWX A;  1ED8 A;  3WAY A;  4UOO A;  1HDH A;  3A52 A;  3IGY B;  1AJC A;  4LRC A;  4B56 A;  4ZGA A;  3TX0 A;  2W5S A;  4KAV A;  1EJJ A;  4YR1 A;  1ALH A;  1E2S P;  3SZY A;  1KH9 A;  2W5T A;  1EQJ A;  3TG0 A;  2IUC A;  5EGH A;  5INH A;  3MK2 A;  2XRG A;  4ZG7 A;  3SZZ A;  1ANJ A;  1ED9 A;  1URB A;  1AUK A;  4KM4 A;  2GSU A; 
#chains in the Genus database with same CATH topology
 3DPC A;  4TN0 A;  4LRD A;  5C66 A;  3MK1 A;  4UOP A;  4LR9 A;  3NKQ A;  3M7V A;  5DLT A;  2GA3 A;  5GRR A;  3E2D A;  4FDJ A;  1ZEF A;  4GTX A;  5IJS A;  3BDF A;  5AJ9 A;  3UN2 A;  1K7H A;  1KHJ A;  2D1G A;  2VQR A;  5DLW A;  4LRE A;  4CYS A;  4CXK A;  1ALJ A;  3CMR A;  5TJ3 A;  1EW8 A;  4GTY A;  4LQY A;  5IJQ A;  3T01 A;  2W5V A;  1O99 A;  4QAX A;  4LR8 A;  3UO0 A;  1SHN A;  3NKR A;  3NKP A;  3KD8 A;  2W8S A;  1SHQ A;  4LR2 A;  1URA A;  3UN3 A;  3OT9 A;  2W8D A;  2QZU A;  5LIA A;  2ANH A;  3UN5 A;  1O98 A;  2W5Q A;  1EW2 A;  1HJK A;  5K4P A;  2X98 A;  1ELZ A;  2GLQ A;  4UPH A;  4LRA A;  4MIV A;  2W5X A;  4CXU A;  5L0B A;  1Y7A A;  1B8J A;  3NKM A;  4ZG6 A;  3WAW A;  2W5R A;  3BDH A;  3Q3Q A;  3LXQ A;  3MK0 A;  1N2K A;  3BDG B;  1AJD A;  2GSN A;  2ZKT A;  3M8Z A;  3UNY A;  3WBH A;  4KAY A;  2GSO A;  5LQQ A;  5L0E A;  1AJA A;  3ED4 A;  3M8Y A;  4KJG A;  4UPK A;  1Y6V A;  1EW9 A;  3T02 A;  3WAV A;  1E33 P;  1E3C P;  1E1Z P;  2XR9 A;  5LRN A;  3TWZ A;  1KHL A;  5KXA A;  4KJD A;  3NVL A;  3NKN A;  2W5W A;  1KHK A;  3DYC A;  4MHX A;  1KH7 A;  1ZED A;  3WAX A;  1KH4 A;  5DLV A;  1N2L A;  1ANI A;  2G9Y A;  2RH6 A;  4CYR A;  1ZEB A;  1ELY A;  1KHN A;  1EI6 A;  4LR7 A;  5HRT A;  4GTZ A;  5LRM A;  1FSU A;  3NKO A;  4MY4 A;  4LRB A;  3M8W A;  4UPI A;  5EGE A;  1ALK A;  1HQA A;  3T00 A;  3B5Q A;  4NWJ A;  4ZG9 A;  3IDD A;  4GTW A;  4FDI A;  4CXS A;  1ELX A;  2IUC B;  4N7T A;  1AJB A;  2IFY A;  5L0K A;  1ALI A;  3BDG A;  4LRF A;  4UPL A;  3IGZ B;  5GOV A;  1P49 A;  4UOR A;  1KH5 A;  4NWX A;  1ED8 A;  3WAY A;  4UOO A;  1HDH A;  3A52 A;  3IGY B;  1AJC A;  4LRC A;  4B56 A;  4ZGA A;  3TX0 A;  2W5S A;  4KAV A;  1EJJ A;  4YR1 A;  1ALH A;  1E2S P;  3SZY A;  1KH9 A;  2W5T A;  1EQJ A;  3TG0 A;  2IUC A;  5EGH A;  5INH A;  3MK2 A;  2XRG A;  4ZG7 A;  3SZZ A;  1ANJ A;  1ED9 A;  1URB A;  1AUK A;  4KM4 A;  2GSU A; 
#chains in the Genus database with same CATH homology
 3DPC A;  4TN0 A;  4LRD A;  5C66 A;  3MK1 A;  4UOP A;  4LR9 A;  3NKQ A;  3M7V A;  5DLT A;  2GA3 A;  5GRR A;  3E2D A;  4FDJ A;  1ZEF A;  4GTX A;  5IJS A;  3BDF A;  5AJ9 A;  3UN2 A;  1K7H A;  1KHJ A;  2D1G A;  2VQR A;  5DLW A;  4LRE A;  4CYS A;  4CXK A;  1ALJ A;  3CMR A;  5TJ3 A;  1EW8 A;  4GTY A;  4LQY A;  5IJQ A;  3T01 A;  2W5V A;  1O99 A;  4QAX A;  4LR8 A;  3UO0 A;  1SHN A;  3NKR A;  3NKP A;  3KD8 A;  2W8S A;  1SHQ A;  4LR2 A;  1URA A;  3UN3 A;  3OT9 A;  2W8D A;  2QZU A;  5LIA A;  2ANH A;  3UN5 A;  1O98 A;  2W5Q A;  1EW2 A;  1HJK A;  5K4P A;  2X98 A;  1ELZ A;  2GLQ A;  4UPH A;  4LRA A;  4MIV A;  2W5X A;  4CXU A;  5L0B A;  1Y7A A;  1B8J A;  3NKM A;  4ZG6 A;  3WAW A;  2W5R A;  3BDH A;  3Q3Q A;  3LXQ A;  3MK0 A;  1N2K A;  3BDG B;  1AJD A;  2GSN A;  2ZKT A;  3M8Z A;  3UNY A;  3WBH A;  4KAY A;  2GSO A;  5LQQ A;  5L0E A;  1AJA A;  3ED4 A;  3M8Y A;  4KJG A;  4UPK A;  1Y6V A;  1EW9 A;  3T02 A;  3WAV A;  1E33 P;  1E3C P;  1E1Z P;  2XR9 A;  5LRN A;  3TWZ A;  1KHL A;  5KXA A;  4KJD A;  3NVL A;  3NKN A;  2W5W A;  1KHK A;  3DYC A;  4MHX A;  1KH7 A;  1ZED A;  3WAX A;  1KH4 A;  5DLV A;  1N2L A;  1ANI A;  2G9Y A;  2RH6 A;  4CYR A;  1ZEB A;  1ELY A;  1KHN A;  1EI6 A;  4LR7 A;  5HRT A;  4GTZ A;  5LRM A;  1FSU A;  3NKO A;  4MY4 A;  4LRB A;  3M8W A;  4UPI A;  5EGE A;  1ALK A;  1HQA A;  3T00 A;  3B5Q A;  4NWJ A;  4ZG9 A;  3IDD A;  4GTW A;  4FDI A;  4CXS A;  1ELX A;  2IUC B;  4N7T A;  1AJB A;  2IFY A;  5L0K A;  1ALI A;  3BDG A;  4LRF A;  4UPL A;  3IGZ B;  5GOV A;  1P49 A;  4UOR A;  1KH5 A;  4NWX A;  1ED8 A;  3WAY A;  4UOO A;  1HDH A;  3A52 A;  3IGY B;  1AJC A;  4LRC A;  4B56 A;  4ZGA A;  3TX0 A;  2W5S A;  4KAV A;  1EJJ A;  4YR1 A;  1ALH A;  1E2S P;  3SZY A;  1KH9 A;  2W5T A;  1EQJ A;  3TG0 A;  2IUC A;  5EGH A;  5INH A;  3MK2 A;  2XRG A;  4ZG7 A;  3SZZ A;  1ANJ A;  1ED9 A;  1URB A;  1AUK A;  4KM4 A;  2GSU A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AJAA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations