1E2SP

Crystal structure of an arylsulfatase a mutant c69a
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
Knots found
sequence length
485
structure length
481
Chain Sequence
RPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLATPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Arylsulfatase A
publication title Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 152
structure length 481
sequence length 485
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.6.8: Cerebroside-sulfatase.
pdb deposition date 2000-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00884 Sulfatase Sulfatase
P PF14707 Sulfatase_C C-terminal region of aryl-sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1120.10 Alpha Beta 2-Layer Sandwich Arylsulfatase, C-terminal domain Arylsulfatase, C-terminal domain 1e2sP02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1e2sP01
3Q3QA 1ED9A 5GOVA 2IUCA 2D1GA 2GSOA 4LR9A 1KHLA 3M8WA 4N7TA 3M7VA 4B56A 1KHNA 1B8JA 3KD8A 4GTWA 1P49A 4KM4A 1Y6VA 3M8YA 1EW2A 1KHJA 3NKMA 1EW8A 4LRFA 1FSUA 5LRMA 4YR1A 3LXQA 3NKQA 5EGEA 1N2KA 4LR2A 1E33P 2W8SA 3IDDA 1KH9A 2GA3A 2W5QA 3MK2A 4LRAA 4KAVA 3NVLA 4LQYA 4UPHA 2RH6A 3ED4A 1O98A 1ZEDA 3UO0A 3UN3A 1K7HA 4UPLA 2GLQA 1ELYA 3BDGB 3NKNA 3UNYA 1E1ZP 2VQRA 1E3CP 1N2LA 2ZKTA 1HDHA 4CXUA 3MK0A 1AJAA 5KXAA 1EW9A 3CMRA 4UORA 3E2DA 1URAA 3DYCA 4UPIA 3B5QA 2X98A 3UN5A 4LR7A 4FDJA 4LRBA 1ELZA 3T00A 4UOPA 5K4PA 1O99A 1SHQA 3WAVA 4CXSA 3WAWA 5LIAA 1ZEBA 5C66A 1KH7A 3WAYA 3NKPA 2IFYA 1EJJA 4ZG9A 5IJSA 3A52A 4MIVA 1ALHA 3SZYA 5IJQA 3T02A 1ALKA 3SZZA 3BDHA 2W5SA 1AJCA 1ZEFA 3DPCA 1EQJA 3WAXA 1HJKA 2IUCB 5L0EA 2W5TA 4KJDA 5INHA 3OT9A 2W5VA 4CYRA 5TJ3A 1URBA 4ZG7A 1AJBA 4UOOA 4ZGAA 2QZUA 3TWZA 5HRTA 2XRGA 2W5WA 1KHKA 4FDIA 1Y7AA 4NWJA 2W8DA 5DLWA 5L0BA 3TX0A 3TG0A 5EGHA 1SHNA 2GSUA 1AUKA 5DLVA 4GTXA 1ED8A 4TN0A 2ANHA 2XR9A 5LRNA 4QAXA 2GSNA 4GTZA 3BDGA 4CXKA 2W5XA 4KJGA 5GRRA 3WBHA 5LQQA 4MHXA 3NKOA 1AJDA 4LRCA 4UPKA 1ELXA 1HQAA 3NKRA 5DLTA 3BDFA 3MK1A 4LRDA 1ANJA 3M8ZA 2G9YA 1ALJA 1E2SP 4MY4A 1ALIA 3T01A 1EI6A 4CYSA 5AJ9A 4LREA 4LR8A 4ZG6A 1ANIA 2W5RA 3IGYB 3UN2A 1KH5A 3IGZB 4GTYA 4NWXA 1KH4A 5L0KA 4KAYA
chains in the Genus database with same CATH superfamily
3Q3QA 4RCPA 1ED9A 3KDRA 2IUCA 5GOVA 3P2ZA 2D1GA 2GSOA 1KHLA 2UV8G 3M8WA 4LR9A 3FS3A 4N7TA 3M7VA 4B56A 1KHNA 1B8JA 4NK7A 4HCOA 4O9WA 5DMVC 3KD8A 4GTWA 1P49A 4KM4A 4E67A 3HMJG 1Y6VA 1EW2A 3M8YA 1KHJA 3NKMA 4NKBA 1EW8A 4LRFA 1FSUA 3HIKA 2I9ZA 4HY2A 2OJXA 4YR1A 3LXQA 5LRMA 3NKQA 5EGEA 1A87A 1F34B 1E33P 1N2KA 3BZIA 2W8SA 3IDDA 4LR2A 1KH9A 2GA3A 2W5QA 3MK2A 4LRAA 4KAVA 1ALJA 3NVLA 4LQYA 2N19A 4UPHA 2RH6A 3ED4A 1O98A 1ZEDA 3UO0A 3RQ7A 3UN3A 1K7HA 4UPLA 2GLQA 1ELYA 4H71A 3BDGB 3NKNA 3UNYA 1E1ZP 2VQRA 1E3CP 1N2LA 2ZKTA 1HDHA 4CXUA 3MK0A 4J7BB 1AJAA 4DFWA 5KXAA 4RS6A 1EW9A 3HFDA 4XB0A 3CMRA 3P35A 4UORA 3E2DA 1URAA 3DYCA 4UPIA 3B5QA 1UMWA 2X98A 3UN5A 5DMSA 4LR7A 4FDJA 3FVHA 4YYPA 4LRBA 1ELZA 3T00A 4UOPA 5K4PA 1O99A 1SHQA 4X9VA 4WHLA 3WAVA 4CXSA 3C5LA 1Q4KA 3WAWA 3LM3A 3GYVA 5LIAA 1ZEBA 5C66A 1KH7A 3WAYA 3NKPA 2IA9A 5DAYA 1EJJA 2IFYA 4ZG9A 3P34A 3A52A 5IJSA 4MIVA 4N7ZA 1ALHA 3SZYA 5IJQA 3T02A 1ALKA 3SZZA 4WHHA 3BDHA 2W5SA 1AJCA 1ZEFA 2E50A 3DPCA 1EQJA 3WAXA 1HJKA 4X9WA 2IUCB 5L0EA 4O6WA 2W5TA 4KJDA 5INHA 3OT9A 2W5VA 4CYRA 5TJ3A 4WHKA 3P2WA 1URBA 4ZG7A 1AJBA 4UOOA 4ZGAA 1Q4OA 2QZUA 3TWZA 5HRTA 2XRGA 4LKLA 2W5WA 4LKMA 4FDIA 1KHKA 1Y7AA 2W8DA 4NWJA 5DLWA 5L0BA 3TX0A 3TG0A 5EGHA 3P36A 3HIHA 1SHNA 2GSUA 1AUKA 2VKZG 4HABA 4GTXA 5DLVA 5DNJA 3Q1IA 1ED8A 4TN0A 2ANHA 2XR9A 5LRNA 4QAXA 2GSNA 4GTZA 3BDGA 3P37A 4X9RA 4CXKA 2W5XA 4KJGA 5GRRA 3WBHA 5LQQA 4MHXA 3NKOA 3GYWA 1AJDA 4E9CA 4LRCA 4UPKA 2I9XA 1ELXA 1HQAA 3NKRA 5DLTA 3BDFA 3MK1A 4LRDA 1ANJA 3M8ZA 2G9YA 4N9JA 1E2SP 4E9DA 5J19A 4MY4A 2OGQA 5LHZA 4H5XA 1ALIA 3T01A 1EI6A 4CYSA 5AJ9A 4LREA 4LR8A 4ZG6A 1ANIA 2W5RA 3IGYB 4G7NA 3UN2A 1KH5A 3IGZB 4GTYA 4N7VA 4NWXA 1KH4A 5L0KA 1F32A 4KAYA 4O56A 1E2TA
chains in the Genus database with same CATH topology
3Q3QA 1ED9A 5GOVA 3KDRA 2IUCA 2D1GA 2GSOA 4LR9A 1KHLA 2UV8G 3M8WA 4N7TA 3FS3A 3M7VA 4B56A 1KHNA 1B8JA 4NK7A 3KD8A 4GTWA 1P49A 4KM4A 1Y6VA 3HMJG 1EW2A 3M8YA 1KHJA 3NKMA 4NKBA 1EW8A 4LRFA 1FSUA 5LRMA 4YR1A 3LXQA 3NKQA 5EGEA 1N2KA 4LR2A 1E33P 2W8SA 3IDDA 1KH9A 2GA3A 2W5QA 3MK2A 4LRAA 4KAVA 3NVLA 4LQYA 4UPHA 2RH6A 3ED4A 1O98A 1ZEDA 3UO0A 3UN3A 1K7HA 4UPLA 2GLQA 1ELYA 3BDGB 3NKNA 3UNYA 1E1ZP 2VQRA 1E3CP 1N2LA 2ZKTA 1HDHA 4CXUA 3MK0A 1AJAA 5KXAA 1EW9A 3HFDA 3CMRA 4UORA 3E2DA 1URAA 3DYCA 4UPIA 3B5QA 2X98A 3UN5A 4LR7A 4FDJA 4LRBA 1ELZA 3T00A 4UOPA 5K4PA 1O99A 1SHQA 3WAVA 4CXSA 3WAWA 3LM3A 3GYVA 5LIAA 1ZEBA 5C66A 1KH7A 3WAYA 3NKPA 5DAYA 1EJJA 2IFYA 4ZG9A 5IJSA 3A52A 4MIVA 4N7ZA 1ALHA 3SZYA 5IJQA 3T02A 1ALKA 3SZZA 3BDHA 2W5SA 1ZEFA 1AJCA 2E50A 3DPCA 1EQJA 3WAXA 1HJKA 2IUCB 5L0EA 2W5TA 4KJDA 5INHA 3OT9A 2W5VA 4CYRA 5TJ3A 1URBA 4ZG7A 1AJBA 4UOOA 4ZGAA 2QZUA 3TWZA 5HRTA 2XRGA 2W5WA 1KHKA 4FDIA 1Y7AA 4NWJA 2W8DA 5DLWA 5L0BA 3TX0A 3TG0A 5EGHA 1SHNA 2GSUA 1AUKA 2VKZG 5DLVA 4GTXA 1ED8A 4TN0A 2ANHA 2XR9A 5LRNA 4QAXA 2GSNA 4GTZA 3BDGA 4CXKA 2W5XA 4KJGA 5GRRA 3WBHA 5LQQA 4MHXA 3NKOA 3GYWA 1AJDA 4LRCA 4UPKA 1ELXA 1HQAA 3NKRA 5DLTA 3BDFA 3MK1A 4LRDA 1ANJA 3M8ZA 2G9YA 4N9JA 1E2SP 4MY4A 1ALJA 1ALIA 3T01A 1EI6A 4CYSA 5AJ9A 4LREA 4LR8A 4ZG6A 1ANIA 2W5RA 3IGYB 4G7NA 3UN2A 1KH5A 3IGZB 4GTYA 4N7VA 4NWXA 1KH4A 5L0KA 4KAYA 1E2TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q3Q A;  1ED9 A;  5GOV A;  2IUC A;  2D1G A;  2GSO A;  4LR9 A;  1KHL A;  3M8W A;  4N7T A;  3M7V A;  4B56 A;  1KHN A;  1B8J A;  3KD8 A;  4GTW A;  1P49 A;  4KM4 A;  1Y6V A;  3M8Y A;  1EW2 A;  1KHJ A;  3NKM A;  1EW8 A;  4LRF A;  1FSU A;  5LRM A;  4YR1 A;  3LXQ A;  3NKQ A;  5EGE A;  1N2K A;  4LR2 A;  1E33 P;  2W8S A;  3IDD A;  1KH9 A;  2GA3 A;  2W5Q A;  3MK2 A;  4LRA A;  4KAV A;  3NVL A;  4LQY A;  4UPH A;  2RH6 A;  3ED4 A;  1O98 A;  1ZED A;  3UO0 A;  3UN3 A;  1K7H A;  4UPL A;  2GLQ A;  1ELY A;  3BDG B;  3NKN A;  3UNY A;  1E1Z P;  2VQR A;  1E3C P;  1N2L A;  2ZKT A;  1HDH A;  4CXU A;  3MK0 A;  1AJA A;  5KXA A;  1EW9 A;  3CMR A;  4UOR A;  3E2D A;  1URA A;  3DYC A;  4UPI A;  3B5Q A;  2X98 A;  3UN5 A;  4LR7 A;  4FDJ A;  4LRB A;  1ELZ A;  3T00 A;  4UOP A;  5K4P A;  1O99 A;  1SHQ A;  3WAV A;  4CXS A;  3WAW A;  5LIA A;  1ZEB A;  5C66 A;  1KH7 A;  3WAY A;  3NKP A;  2IFY A;  1EJJ A;  4ZG9 A;  5IJS A;  3A52 A;  4MIV A;  1ALH A;  3SZY A;  5IJQ A;  3T02 A;  1ALK A;  3SZZ A;  3BDH A;  2W5S A;  1AJC A;  1ZEF A;  3DPC A;  1EQJ A;  3WAX A;  1HJK A;  2IUC B;  5L0E A;  2W5T A;  4KJD A;  5INH A;  3OT9 A;  2W5V A;  4CYR A;  5TJ3 A;  1URB A;  4ZG7 A;  1AJB A;  4UOO A;  4ZGA A;  2QZU A;  3TWZ A;  5HRT A;  2XRG A;  2W5W A;  1KHK A;  4FDI A;  1Y7A A;  4NWJ A;  2W8D A;  5DLW A;  5L0B A;  3TX0 A;  3TG0 A;  5EGH A;  1SHN A;  2GSU A;  1AUK A;  5DLV A;  4GTX A;  1ED8 A;  4TN0 A;  2ANH A;  2XR9 A;  5LRN A;  4QAX A;  2GSN A;  4GTZ A;  3BDG A;  4CXK A;  2W5X A;  4KJG A;  5GRR A;  3WBH A;  5LQQ A;  4MHX A;  3NKO A;  1AJD A;  4LRC A;  4UPK A;  1ELX A;  1HQA A;  3NKR A;  5DLT A;  3BDF A;  3MK1 A;  4LRD A;  1ANJ A;  3M8Z A;  2G9Y A;  1ALJ A;  1E2S P;  4MY4 A;  1ALI A;  3T01 A;  1EI6 A;  4CYS A;  5AJ9 A;  4LRE A;  4LR8 A;  4ZG6 A;  1ANI A;  2W5R A;  3IGY B;  3UN2 A;  1KH5 A;  3IGZ B;  4GTY A;  4NWX A;  1KH4 A;  5L0K A;  4KAY A; 
#chains in the Genus database with same CATH topology
 3Q3Q A;  4RCP A;  1ED9 A;  3KDR A;  2IUC A;  5GOV A;  3P2Z A;  2D1G A;  2GSO A;  1KHL A;  2UV8 G;  3M8W A;  4LR9 A;  3FS3 A;  4N7T A;  3M7V A;  4B56 A;  1KHN A;  1B8J A;  4NK7 A;  4HCO A;  4O9W A;  5DMV C;  3KD8 A;  4GTW A;  1P49 A;  4KM4 A;  4E67 A;  3HMJ G;  1Y6V A;  1EW2 A;  3M8Y A;  1KHJ A;  3NKM A;  4NKB A;  1EW8 A;  4LRF A;  1FSU A;  3HIK A;  2I9Z A;  4HY2 A;  2OJX A;  4YR1 A;  3LXQ A;  5LRM A;  3NKQ A;  5EGE A;  1A87 A;  1F34 B;  1E33 P;  1N2K A;  3BZI A;  2W8S A;  3IDD A;  4LR2 A;  1KH9 A;  2GA3 A;  2W5Q A;  3MK2 A;  4LRA A;  4KAV A;  1ALJ A;  3NVL A;  4LQY A;  2N19 A;  4UPH A;  2RH6 A;  3ED4 A;  1O98 A;  1ZED A;  3UO0 A;  3RQ7 A;  3UN3 A;  1K7H A;  4UPL A;  2GLQ A;  1ELY A;  4H71 A;  3BDG B;  3NKN A;  3UNY A;  1E1Z P;  2VQR A;  1E3C P;  1N2L A;  2ZKT A;  1HDH A;  4CXU A;  3MK0 A;  4J7B B;  1AJA A;  4DFW A;  5KXA A;  4RS6 A;  1EW9 A;  3HFD A;  4XB0 A;  3CMR A;  3P35 A;  4UOR A;  3E2D A;  1URA A;  3DYC A;  4UPI A;  3B5Q A;  1UMW A;  2X98 A;  3UN5 A;  5DMS A;  4LR7 A;  4FDJ A;  3FVH A;  4YYP A;  4LRB A;  1ELZ A;  3T00 A;  4UOP A;  5K4P A;  1O99 A;  1SHQ A;  4X9V A;  4WHL A;  3WAV A;  4CXS A;  3C5L A;  1Q4K A;  3WAW A;  3LM3 A;  3GYV A;  5LIA A;  1ZEB A;  5C66 A;  1KH7 A;  3WAY A;  3NKP A;  2IA9 A;  5DAY A;  1EJJ A;  2IFY A;  4ZG9 A;  3P34 A;  3A52 A;  5IJS A;  4MIV A;  4N7Z A;  1ALH A;  3SZY A;  5IJQ A;  3T02 A;  1ALK A;  3SZZ A;  4WHH A;  3BDH A;  2W5S A;  1AJC A;  1ZEF A;  2E50 A;  3DPC A;  1EQJ A;  3WAX A;  1HJK A;  4X9W A;  2IUC B;  5L0E A;  4O6W A;  2W5T A;  4KJD A;  5INH A;  3OT9 A;  2W5V A;  4CYR A;  5TJ3 A;  4WHK A;  3P2W A;  1URB A;  4ZG7 A;  1AJB A;  4UOO A;  4ZGA A;  1Q4O A;  2QZU A;  3TWZ A;  5HRT A;  2XRG A;  4LKL A;  2W5W A;  4LKM A;  4FDI A;  1KHK A;  1Y7A A;  2W8D A;  4NWJ A;  5DLW A;  5L0B A;  3TX0 A;  3TG0 A;  5EGH A;  3P36 A;  3HIH A;  1SHN A;  2GSU A;  1AUK A;  2VKZ G;  4HAB A;  4GTX A;  5DLV A;  5DNJ A;  3Q1I A;  1ED8 A;  4TN0 A;  2ANH A;  2XR9 A;  5LRN A;  4QAX A;  2GSN A;  4GTZ A;  3BDG A;  3P37 A;  4X9R A;  4CXK A;  2W5X A;  4KJG A;  5GRR A;  3WBH A;  5LQQ A;  4MHX A;  3NKO A;  3GYW A;  1AJD A;  4E9C A;  4LRC A;  4UPK A;  2I9X A;  1ELX A;  1HQA A;  3NKR A;  5DLT A;  3BDF A;  3MK1 A;  4LRD A;  1ANJ A;  3M8Z A;  2G9Y A;  4N9J A;  1E2S P;  4E9D A;  5J19 A;  4MY4 A;  2OGQ A;  5LHZ A;  4H5X A;  1ALI A;  3T01 A;  1EI6 A;  4CYS A;  5AJ9 A;  4LRE A;  4LR8 A;  4ZG6 A;  1ANI A;  2W5R A;  3IGY B;  4G7N A;  3UN2 A;  1KH5 A;  3IGZ B;  4GTY A;  4N7V A;  4NWX A;  1KH4 A;  5L0K A;  1F32 A;  4KAY A;  4O56 A;  1E2T A; 
#chains in the Genus database with same CATH homology
 3Q3Q A;  1ED9 A;  5GOV A;  3KDR A;  2IUC A;  2D1G A;  2GSO A;  4LR9 A;  1KHL A;  2UV8 G;  3M8W A;  4N7T A;  3FS3 A;  3M7V A;  4B56 A;  1KHN A;  1B8J A;  4NK7 A;  3KD8 A;  4GTW A;  1P49 A;  4KM4 A;  1Y6V A;  3HMJ G;  1EW2 A;  3M8Y A;  1KHJ A;  3NKM A;  4NKB A;  1EW8 A;  4LRF A;  1FSU A;  5LRM A;  4YR1 A;  3LXQ A;  3NKQ A;  5EGE A;  1N2K A;  4LR2 A;  1E33 P;  2W8S A;  3IDD A;  1KH9 A;  2GA3 A;  2W5Q A;  3MK2 A;  4LRA A;  4KAV A;  3NVL A;  4LQY A;  4UPH A;  2RH6 A;  3ED4 A;  1O98 A;  1ZED A;  3UO0 A;  3UN3 A;  1K7H A;  4UPL A;  2GLQ A;  1ELY A;  3BDG B;  3NKN A;  3UNY A;  1E1Z P;  2VQR A;  1E3C P;  1N2L A;  2ZKT A;  1HDH A;  4CXU A;  3MK0 A;  1AJA A;  5KXA A;  1EW9 A;  3HFD A;  3CMR A;  4UOR A;  3E2D A;  1URA A;  3DYC A;  4UPI A;  3B5Q A;  2X98 A;  3UN5 A;  4LR7 A;  4FDJ A;  4LRB A;  1ELZ A;  3T00 A;  4UOP A;  5K4P A;  1O99 A;  1SHQ A;  3WAV A;  4CXS A;  3WAW A;  3LM3 A;  3GYV A;  5LIA A;  1ZEB A;  5C66 A;  1KH7 A;  3WAY A;  3NKP A;  5DAY A;  1EJJ A;  2IFY A;  4ZG9 A;  5IJS A;  3A52 A;  4MIV A;  4N7Z A;  1ALH A;  3SZY A;  5IJQ A;  3T02 A;  1ALK A;  3SZZ A;  3BDH A;  2W5S A;  1ZEF A;  1AJC A;  2E50 A;  3DPC A;  1EQJ A;  3WAX A;  1HJK A;  2IUC B;  5L0E A;  2W5T A;  4KJD A;  5INH A;  3OT9 A;  2W5V A;  4CYR A;  5TJ3 A;  1URB A;  4ZG7 A;  1AJB A;  4UOO A;  4ZGA A;  2QZU A;  3TWZ A;  5HRT A;  2XRG A;  2W5W A;  1KHK A;  4FDI A;  1Y7A A;  4NWJ A;  2W8D A;  5DLW A;  5L0B A;  3TX0 A;  3TG0 A;  5EGH A;  1SHN A;  2GSU A;  1AUK A;  2VKZ G;  5DLV A;  4GTX A;  1ED8 A;  4TN0 A;  2ANH A;  2XR9 A;  5LRN A;  4QAX A;  2GSN A;  4GTZ A;  3BDG A;  4CXK A;  2W5X A;  4KJG A;  5GRR A;  3WBH A;  5LQQ A;  4MHX A;  3NKO A;  3GYW A;  1AJD A;  4LRC A;  4UPK A;  1ELX A;  1HQA A;  3NKR A;  5DLT A;  3BDF A;  3MK1 A;  4LRD A;  1ANJ A;  3M8Z A;  2G9Y A;  4N9J A;  1E2S P;  4MY4 A;  1ALJ A;  1ALI A;  3T01 A;  1EI6 A;  4CYS A;  5AJ9 A;  4LRE A;  4LR8 A;  4ZG6 A;  1ANI A;  2W5R A;  3IGY B;  4G7N A;  3UN2 A;  1KH5 A;  3IGZ B;  4GTY A;  4N7V A;  4NWX A;  1KH4 A;  5L0K A;  4KAY A;  1E2T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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