1AJC | Genus

Total Genus 160

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	160
Knots found	KnotProt 2.0: S +3₁
sequence length	449
structure length	446
Chain Sequence	TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQGATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAEARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Non specific mono-esterase
source organism	Escherichia coli
publication title	Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase. pubmed doi rcsb
molecule keywords	ALKALINE PHOSPHATASE
total genus	160
structure length	446
sequence length	449
chains with identical sequence	B
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	1995-07-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1ajcA00

4CYSA 2GSOA 3NKQA 1ELZA 4KM4A 4NWJA 5DLTA 3MK1A 1ELYA 2W5VA 4KJDA 1Y6VA 1ANJA 3LXQA 1N2KA 3ED4A 3NKPA 4KJGA 3UN3A 2XR9A 1HDHA 2W5RA 1ZEBA 5EGEA 3A52A 1KHNA 1KHJA 4GTWA 2G9YA 3UN5A 1ED8A 1ALKA 1SHQA 3BDGA 3BDGB 4UPLA 2VQRA 3M7VA 2X98A 4QAXA 1AUKA 3B5QA 4UOPA 1E3CP 3TWZA 3WBHA 5IJSA 3NVLA 5HRTA 4LR8A 2ANHA 3KD8A 5DLWA 4LQYA 4NWXA 5LRNA 5LIAA 5C66A 5DLVA 1URAA 3IGZB 4LREA 3NKMA 3UN2A 1ALIA 3E2DA 1EW2A 3SZYA 3Q3QA 4N7TA 1HJKA 5EGHA 3NKRA 2IFYA 1EJJA 5INHA 2GSUA 5L0BA 3IDDA 3M8YA 4UPIA 1AJCA 4UOOA 3WAYA 2W5TA 4MHXA 3DPCA 1ZEFA 1B8JA 1KH4A 5IJQA 3WAVA 5KXAA 1EW8A 5TJ3A 1EQJA 1KHLA 1ZEDA 2GSNA 1O98A 1P49A 3NKNA 4FDJA 4MY4A 3T01A 5L0EA 3CMRA 4KAYA 4UPKA 1ALJA 1AJAA 3WAXA 2GA3A 1ALHA 2W5XA 4GTZA 4LR7A 4B56A 2W5WA 3DYCA 4TN0A 3UO0A 3NKOA 4GTXA 4ZG6A 1ED9A 4LRDA 4ZG9A 4YR1A 1URBA 3UNYA 2W8SA 4ZGAA 3TG0A 4CXSA 4LRFA 3BDFA 1Y7AA 3BDHA 3MK2A 4KAVA 1E1ZP 1O99A 3WAWA 4UORA 1AJBA 3MK0A 3SZZA 4LR9A 1KH5A 1EW9A 4FDIA 4LRBA 5L0KA 2XRGA 1E33P 2RH6A 2W5SA 3TX0A 2W8DA 5LQQA 2IUCA 2IUCB 1ELXA 1KHKA 5GRRA 3T00A 4UPHA 4ZG7A 3M8ZA 3OT9A 5GOVA 1AJDA 4LRAA 3IGYB 4LRCA 1N2LA 4CXKA 1SHNA 1E2SP 1FSUA 5K4PA 4LR2A 3T02A 1KH9A 1ANIA 1HQAA 2W5QA 3M8WA 5LRMA 2QZUA 1KH7A 1EI6A 4CXUA 4CYRA 2GLQA 4MIVA 2ZKTA 2D1GA 4GTYA 1K7HA 5AJ9A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4CYS A;  2GSO A;  3NKQ A;  1ELZ A;  4KM4 A;  4NWJ A;  5DLT A;  3MK1 A;  1ELY A;  2W5V A;  4KJD A;  1Y6V A;  1ANJ A;  3LXQ A;  1N2K A;  3ED4 A;  3NKP A;  4KJG A;  3UN3 A;  2XR9 A;  1HDH A;  2W5R A;  1ZEB A;  5EGE A;  3A52 A;  1KHN A;  1KHJ A;  4GTW A;  2G9Y A;  3UN5 A;  1ED8 A;  1ALK A;  1SHQ A;  3BDG A;  3BDG B;  4UPL A;  2VQR A;  3M7V A;  2X98 A;  4QAX A;  1AUK A;  3B5Q A;  4UOP A;  1E3C P;  3TWZ A;  3WBH A;  5IJS A;  3NVL A;  5HRT A;  4LR8 A;  2ANH A;  3KD8 A;  5DLW A;  4LQY A;  4NWX A;  5LRN A;  5LIA A;  5C66 A;  5DLV A;  1URA A;  3IGZ B;  4LRE A;  3NKM A;  3UN2 A;  1ALI A;  3E2D A;  1EW2 A;  3SZY A;  3Q3Q A;  4N7T A;  1HJK A;  5EGH A;  3NKR A;  2IFY A;  1EJJ A;  5INH A;  2GSU A;  5L0B A;  3IDD A;  3M8Y A;  4UPI A;  1AJC A;  4UOO A;  3WAY A;  2W5T A;  4MHX A;  3DPC A;  1ZEF A;  1B8J A;  1KH4 A;  5IJQ A;  3WAV A;  5KXA A;  1EW8 A;  5TJ3 A;  1EQJ A;  1KHL A;  1ZED A;  2GSN A;  1O98 A;  1P49 A;  3NKN A;  4FDJ A;  4MY4 A;  3T01 A;  5L0E A;  3CMR A;  4KAY A;  4UPK A;  1ALJ A;  1AJA A;  3WAX A;  2GA3 A;  1ALH A;  2W5X A;  4GTZ A;  4LR7 A;  4B56 A;  2W5W A;  3DYC A;  4TN0 A;  3UO0 A;  3NKO A;  4GTX A;  4ZG6 A;  1ED9 A;  4LRD A;  4ZG9 A;  4YR1 A;  1URB A;  3UNY A;  2W8S A;  4ZGA A;  3TG0 A;  4CXS A;  4LRF A;  3BDF A;  1Y7A A;  3BDH A;  3MK2 A;  4KAV A;  1E1Z P;  1O99 A;  3WAW A;  4UOR A;  1AJB A;  3MK0 A;  3SZZ A;  4LR9 A;  1KH5 A;  1EW9 A;  4FDI A;  4LRB A;  5L0K A;  2XRG A;  1E33 P;  2RH6 A;  2W5S A;  3TX0 A;  2W8D A;  5LQQ A;  2IUC A;  2IUC B;  1ELX A;  1KHK A;  5GRR A;  3T00 A;  4UPH A;  4ZG7 A;  3M8Z A;  3OT9 A;  5GOV A;  1AJD A;  4LRA A;  3IGY B;  4LRC A;  1N2L A;  4CXK A;  1SHN A;  1E2S P;  1FSU A;  5K4P A;  4LR2 A;  3T02 A;  1KH9 A;  1ANI A;  1HQA A;  2W5Q A;  3M8W A;  5LRM A;  2QZU A;  1KH7 A;  1EI6 A;  4CXU A;  4CYR A;  2GLQ A;  4MIV A;  2ZKT A;  2D1G A;  4GTY A;  1K7H A;  5AJ9 A; 
#chains in the Genus database with same CATH topology
 4CYS A;  2GSO A;  3NKQ A;  1ELZ A;  4KM4 A;  4NWJ A;  5DLT A;  3MK1 A;  1ELY A;  2W5V A;  4KJD A;  1Y6V A;  1ANJ A;  3LXQ A;  1N2K A;  3ED4 A;  3NKP A;  4KJG A;  3UN3 A;  2XR9 A;  1HDH A;  2W5R A;  1ZEB A;  5EGE A;  3A52 A;  1KHN A;  1KHJ A;  4GTW A;  2G9Y A;  3UN5 A;  1ED8 A;  1ALK A;  1SHQ A;  3BDG A;  3BDG B;  4UPL A;  2VQR A;  3M7V A;  2X98 A;  4QAX A;  1AUK A;  3B5Q A;  4UOP A;  1E3C P;  3TWZ A;  3WBH A;  5IJS A;  3NVL A;  5HRT A;  4LR8 A;  2ANH A;  3KD8 A;  5DLW A;  4LQY A;  4NWX A;  5LRN A;  5LIA A;  5C66 A;  5DLV A;  1URA A;  3IGZ B;  4LRE A;  3NKM A;  3UN2 A;  1ALI A;  3E2D A;  1EW2 A;  3SZY A;  3Q3Q A;  4N7T A;  1HJK A;  5EGH A;  3NKR A;  2IFY A;  1EJJ A;  5INH A;  2GSU A;  5L0B A;  3IDD A;  3M8Y A;  4UPI A;  1AJC A;  4UOO A;  3WAY A;  2W5T A;  4MHX A;  3DPC A;  1ZEF A;  1B8J A;  1KH4 A;  5IJQ A;  3WAV A;  5KXA A;  1EW8 A;  5TJ3 A;  1EQJ A;  1KHL A;  1ZED A;  2GSN A;  1O98 A;  1P49 A;  3NKN A;  4FDJ A;  4MY4 A;  3T01 A;  5L0E A;  3CMR A;  4KAY A;  4UPK A;  1ALJ A;  1AJA A;  3WAX A;  2GA3 A;  1ALH A;  2W5X A;  4GTZ A;  4LR7 A;  4B56 A;  2W5W A;  3DYC A;  4TN0 A;  3UO0 A;  3NKO A;  4GTX A;  4ZG6 A;  1ED9 A;  4LRD A;  4ZG9 A;  4YR1 A;  1URB A;  3UNY A;  2W8S A;  4ZGA A;  3TG0 A;  4CXS A;  4LRF A;  3BDF A;  1Y7A A;  3BDH A;  3MK2 A;  4KAV A;  1E1Z P;  1O99 A;  3WAW A;  4UOR A;  1AJB A;  3MK0 A;  3SZZ A;  4LR9 A;  1KH5 A;  1EW9 A;  4FDI A;  4LRB A;  5L0K A;  2XRG A;  1E33 P;  2RH6 A;  2W5S A;  3TX0 A;  2W8D A;  5LQQ A;  2IUC A;  2IUC B;  1ELX A;  1KHK A;  5GRR A;  3T00 A;  4UPH A;  4ZG7 A;  3M8Z A;  3OT9 A;  5GOV A;  1AJD A;  4LRA A;  3IGY B;  4LRC A;  1N2L A;  4CXK A;  1SHN A;  1E2S P;  1FSU A;  5K4P A;  4LR2 A;  3T02 A;  1KH9 A;  1ANI A;  1HQA A;  2W5Q A;  3M8W A;  5LRM A;  2QZU A;  1KH7 A;  1EI6 A;  4CXU A;  4CYR A;  2GLQ A;  4MIV A;  2ZKT A;  2D1G A;  4GTY A;  1K7H A;  5AJ9 A; 
#chains in the Genus database with same CATH homology
 4CYS A;  2GSO A;  3NKQ A;  1ELZ A;  4KM4 A;  4NWJ A;  5DLT A;  3MK1 A;  1ELY A;  2W5V A;  4KJD A;  1Y6V A;  1ANJ A;  3LXQ A;  1N2K A;  3ED4 A;  3NKP A;  4KJG A;  3UN3 A;  2XR9 A;  1HDH A;  2W5R A;  1ZEB A;  5EGE A;  3A52 A;  1KHN A;  1KHJ A;  4GTW A;  2G9Y A;  3UN5 A;  1ED8 A;  1ALK A;  1SHQ A;  3BDG A;  3BDG B;  4UPL A;  2VQR A;  3M7V A;  2X98 A;  4QAX A;  1AUK A;  3B5Q A;  4UOP A;  1E3C P;  3TWZ A;  3WBH A;  5IJS A;  3NVL A;  5HRT A;  4LR8 A;  2ANH A;  3KD8 A;  5DLW A;  4LQY A;  4NWX A;  5LRN A;  5LIA A;  5C66 A;  5DLV A;  1URA A;  3IGZ B;  4LRE A;  3NKM A;  3UN2 A;  1ALI A;  3E2D A;  1EW2 A;  3SZY A;  3Q3Q A;  4N7T A;  1HJK A;  5EGH A;  3NKR A;  2IFY A;  1EJJ A;  5INH A;  2GSU A;  5L0B A;  3IDD A;  3M8Y A;  4UPI A;  1AJC A;  4UOO A;  3WAY A;  2W5T A;  4MHX A;  3DPC A;  1ZEF A;  1B8J A;  1KH4 A;  5IJQ A;  3WAV A;  5KXA A;  1EW8 A;  5TJ3 A;  1EQJ A;  1KHL A;  1ZED A;  2GSN A;  1O98 A;  1P49 A;  3NKN A;  4FDJ A;  4MY4 A;  3T01 A;  5L0E A;  3CMR A;  4KAY A;  4UPK A;  1ALJ A;  1AJA A;  3WAX A;  2GA3 A;  1ALH A;  2W5X A;  4GTZ A;  4LR7 A;  4B56 A;  2W5W A;  3DYC A;  4TN0 A;  3UO0 A;  3NKO A;  4GTX A;  4ZG6 A;  1ED9 A;  4LRD A;  4ZG9 A;  4YR1 A;  1URB A;  3UNY A;  2W8S A;  4ZGA A;  3TG0 A;  4CXS A;  4LRF A;  3BDF A;  1Y7A A;  3BDH A;  3MK2 A;  4KAV A;  1E1Z P;  1O99 A;  3WAW A;  4UOR A;  1AJB A;  3MK0 A;  3SZZ A;  4LR9 A;  1KH5 A;  1EW9 A;  4FDI A;  4LRB A;  5L0K A;  2XRG A;  1E33 P;  2RH6 A;  2W5S A;  3TX0 A;  2W8D A;  5LQQ A;  2IUC A;  2IUC B;  1ELX A;  1KHK A;  5GRR A;  3T00 A;  4UPH A;  4ZG7 A;  3M8Z A;  3OT9 A;  5GOV A;  1AJD A;  4LRA A;  3IGY B;  4LRC A;  1N2L A;  4CXK A;  1SHN A;  1E2S P;  1FSU A;  5K4P A;  4LR2 A;  3T02 A;  1KH9 A;  1ANI A;  1HQA A;  2W5Q A;  3M8W A;  5LRM A;  2QZU A;  1KH7 A;  1EI6 A;  4CXU A;  4CYR A;  2GLQ A;  4MIV A;  2ZKT A;  2D1G A;  4GTY A;  1K7H A;  5AJ9 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AJCA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations