1ELZ | Genus

Total Genus 157

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	157
Knots found	KnotProt 2.0: S +3₁
sequence length	449
structure length	449
Chain Sequence	TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDGAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Hydrolase
source organism	Escherichia coli
publication title	Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102. pubmed doi rcsb
molecule keywords	ALKALINE PHOSPHATASE
total genus	157
structure length	449
sequence length	449
chains with identical sequence	B
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	1998-02-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1elzA00

1Y6VA 3IGZB 2IUCA 5C66A 1E3CP 1KHJA 4UOPA 5K4PA 5IJSA 2IUCB 4LQYA 1FSUA 3M8ZA 1EI6A 1ED8A 1AJCA 1E2SP 4LRFA 3TG0A 3UN5A 4CXUA 1K7HA 2ZKTA 4FDJA 3NKQA 4UPKA 5LRNA 3M7VA 4FDIA 1KHLA 2IFYA 4LR9A 3IGYB 3UN2A 5DLWA 4LRCA 5LQQA 1N2LA 1HJKA 3Q3QA 1ZEBA 4QAXA 2W5RA 3DYCA 1ALJA 4LREA 3TX0A 4KJDA 2GSNA 3MK1A 1ZEFA 1EW9A 3E2DA 5GOVA 4MY4A 2W8SA 4TN0A 4CXSA 2W5TA 1AJBA 1ANIA 2G9YA 3MK2A 1URAA 1ED9A 4GTZA 3UO0A 5TJ3A 3NVLA 4NWXA 1KH5A 1EW8A 4GTXA 4YR1A 5L0KA 5L0BA 1B8JA 1Y7AA 4GTYA 4MIVA 1EJJA 2RH6A 1ZEDA 3BDFA 3T00A 4ZG7A 2W5SA 5L0EA 3BDGA 5INHA 4LRDA 5EGHA 4UPHA 3A52A 2D1GA 3BDGB 2GA3A 3NKOA 3NKMA 1SHNA 1E33P 1HQAA 2GSUA 3B5QA 5LIAA 3WAWA 1KH9A 2ANHA 1O98A 1ANJA 2W5VA 5DLTA 1SHQA 4UORA 4UPLA 2VQRA 4UOOA 2GSOA 1KHNA 3SZYA 4NWJA 3NKNA 3IDDA 3SZZA 3TWZA 3DPCA 4LR2A 4CYSA 1KHKA 1EW2A 5AJ9A 3WBHA 2XR9A 5LRMA 1AJAA 3T01A 5HRTA 1ELYA 4ZG6A 4GTWA 3MK0A 2XRGA 3ED4A 1URBA 3NKRA 1ELXA 1O99A 5GRRA 2W8DA 2W5WA 4CXKA 4LR8A 1P49A 4MHXA 1EQJA 1KH4A 1AUKA 4UPIA 2GLQA 2W5QA 5KXAA 1HDHA 3M8WA 3UN3A 4LR7A 4B56A 1ELZA 2X98A 3NKPA 1AJDA 4LRAA 5IJQA 1ALIA 3WAYA 4CYRA 1KH7A 4KAVA 3T02A 4ZGAA 4ZG9A 3OT9A 5DLVA 1ALHA 3UNYA 4N7TA 1ALKA 1E1ZP 4KAYA 3CMRA 2W5XA 4LRBA 5EGEA 2QZUA 4KM4A 1N2KA 3KD8A 3M8YA 3LXQA 4KJGA 3WAXA 3WAVA 3BDHA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1Y6V A;  3IGZ B;  2IUC A;  5C66 A;  1E3C P;  1KHJ A;  4UOP A;  5K4P A;  5IJS A;  2IUC B;  4LQY A;  1FSU A;  3M8Z A;  1EI6 A;  1ED8 A;  1AJC A;  1E2S P;  4LRF A;  3TG0 A;  3UN5 A;  4CXU A;  1K7H A;  2ZKT A;  4FDJ A;  3NKQ A;  4UPK A;  5LRN A;  3M7V A;  4FDI A;  1KHL A;  2IFY A;  4LR9 A;  3IGY B;  3UN2 A;  5DLW A;  4LRC A;  5LQQ A;  1N2L A;  1HJK A;  3Q3Q A;  1ZEB A;  4QAX A;  2W5R A;  3DYC A;  1ALJ A;  4LRE A;  3TX0 A;  4KJD A;  2GSN A;  3MK1 A;  1ZEF A;  1EW9 A;  3E2D A;  5GOV A;  4MY4 A;  2W8S A;  4TN0 A;  4CXS A;  2W5T A;  1AJB A;  1ANI A;  2G9Y A;  3MK2 A;  1URA A;  1ED9 A;  4GTZ A;  3UO0 A;  5TJ3 A;  3NVL A;  4NWX A;  1KH5 A;  1EW8 A;  4GTX A;  4YR1 A;  5L0K A;  5L0B A;  1B8J A;  1Y7A A;  4GTY A;  4MIV A;  1EJJ A;  2RH6 A;  1ZED A;  3BDF A;  3T00 A;  4ZG7 A;  2W5S A;  5L0E A;  3BDG A;  5INH A;  4LRD A;  5EGH A;  4UPH A;  3A52 A;  2D1G A;  3BDG B;  2GA3 A;  3NKO A;  3NKM A;  1SHN A;  1E33 P;  1HQA A;  2GSU A;  3B5Q A;  5LIA A;  3WAW A;  1KH9 A;  2ANH A;  1O98 A;  1ANJ A;  2W5V A;  5DLT A;  1SHQ A;  4UOR A;  4UPL A;  2VQR A;  4UOO A;  2GSO A;  1KHN A;  3SZY A;  4NWJ A;  3NKN A;  3IDD A;  3SZZ A;  3TWZ A;  3DPC A;  4LR2 A;  4CYS A;  1KHK A;  1EW2 A;  5AJ9 A;  3WBH A;  2XR9 A;  5LRM A;  1AJA A;  3T01 A;  5HRT A;  1ELY A;  4ZG6 A;  4GTW A;  3MK0 A;  2XRG A;  3ED4 A;  1URB A;  3NKR A;  1ELX A;  1O99 A;  5GRR A;  2W8D A;  2W5W A;  4CXK A;  4LR8 A;  1P49 A;  4MHX A;  1EQJ A;  1KH4 A;  1AUK A;  4UPI A;  2GLQ A;  2W5Q A;  5KXA A;  1HDH A;  3M8W A;  3UN3 A;  4LR7 A;  4B56 A;  1ELZ A;  2X98 A;  3NKP A;  1AJD A;  4LRA A;  5IJQ A;  1ALI A;  3WAY A;  4CYR A;  1KH7 A;  4KAV A;  3T02 A;  4ZGA A;  4ZG9 A;  3OT9 A;  5DLV A;  1ALH A;  3UNY A;  4N7T A;  1ALK A;  1E1Z P;  4KAY A;  3CMR A;  2W5X A;  4LRB A;  5EGE A;  2QZU A;  4KM4 A;  1N2K A;  3KD8 A;  3M8Y A;  3LXQ A;  4KJG A;  3WAX A;  3WAV A;  3BDH A; 
#chains in the Genus database with same CATH topology
 1Y6V A;  3IGZ B;  2IUC A;  5C66 A;  1E3C P;  1KHJ A;  4UOP A;  5K4P A;  5IJS A;  2IUC B;  4LQY A;  1FSU A;  3M8Z A;  1EI6 A;  1ED8 A;  1AJC A;  1E2S P;  4LRF A;  3TG0 A;  3UN5 A;  4CXU A;  1K7H A;  2ZKT A;  4FDJ A;  3NKQ A;  4UPK A;  5LRN A;  3M7V A;  4FDI A;  1KHL A;  2IFY A;  4LR9 A;  3IGY B;  3UN2 A;  5DLW A;  4LRC A;  5LQQ A;  1N2L A;  1HJK A;  3Q3Q A;  1ZEB A;  4QAX A;  2W5R A;  3DYC A;  1ALJ A;  4LRE A;  3TX0 A;  4KJD A;  2GSN A;  3MK1 A;  1ZEF A;  1EW9 A;  3E2D A;  5GOV A;  4MY4 A;  2W8S A;  4TN0 A;  4CXS A;  2W5T A;  1AJB A;  1ANI A;  2G9Y A;  3MK2 A;  1URA A;  1ED9 A;  4GTZ A;  3UO0 A;  5TJ3 A;  3NVL A;  4NWX A;  1KH5 A;  1EW8 A;  4GTX A;  4YR1 A;  5L0K A;  5L0B A;  1B8J A;  1Y7A A;  4GTY A;  4MIV A;  1EJJ A;  2RH6 A;  1ZED A;  3BDF A;  3T00 A;  4ZG7 A;  2W5S A;  5L0E A;  3BDG A;  5INH A;  4LRD A;  5EGH A;  4UPH A;  3A52 A;  2D1G A;  3BDG B;  2GA3 A;  3NKO A;  3NKM A;  1SHN A;  1E33 P;  1HQA A;  2GSU A;  3B5Q A;  5LIA A;  3WAW A;  1KH9 A;  2ANH A;  1O98 A;  1ANJ A;  2W5V A;  5DLT A;  1SHQ A;  4UOR A;  4UPL A;  2VQR A;  4UOO A;  2GSO A;  1KHN A;  3SZY A;  4NWJ A;  3NKN A;  3IDD A;  3SZZ A;  3TWZ A;  3DPC A;  4LR2 A;  4CYS A;  1KHK A;  1EW2 A;  5AJ9 A;  3WBH A;  2XR9 A;  5LRM A;  1AJA A;  3T01 A;  5HRT A;  1ELY A;  4ZG6 A;  4GTW A;  3MK0 A;  2XRG A;  3ED4 A;  1URB A;  3NKR A;  1ELX A;  1O99 A;  5GRR A;  2W8D A;  2W5W A;  4CXK A;  4LR8 A;  1P49 A;  4MHX A;  1EQJ A;  1KH4 A;  1AUK A;  4UPI A;  2GLQ A;  2W5Q A;  5KXA A;  1HDH A;  3M8W A;  3UN3 A;  4LR7 A;  4B56 A;  1ELZ A;  2X98 A;  3NKP A;  1AJD A;  4LRA A;  5IJQ A;  1ALI A;  3WAY A;  4CYR A;  1KH7 A;  4KAV A;  3T02 A;  4ZGA A;  4ZG9 A;  3OT9 A;  5DLV A;  1ALH A;  3UNY A;  4N7T A;  1ALK A;  1E1Z P;  4KAY A;  3CMR A;  2W5X A;  4LRB A;  5EGE A;  2QZU A;  4KM4 A;  1N2K A;  3KD8 A;  3M8Y A;  3LXQ A;  4KJG A;  3WAX A;  3WAV A;  3BDH A; 
#chains in the Genus database with same CATH homology
 1Y6V A;  3IGZ B;  2IUC A;  5C66 A;  1E3C P;  1KHJ A;  4UOP A;  5K4P A;  5IJS A;  2IUC B;  4LQY A;  1FSU A;  3M8Z A;  1EI6 A;  1ED8 A;  1AJC A;  1E2S P;  4LRF A;  3TG0 A;  3UN5 A;  4CXU A;  1K7H A;  2ZKT A;  4FDJ A;  3NKQ A;  4UPK A;  5LRN A;  3M7V A;  4FDI A;  1KHL A;  2IFY A;  4LR9 A;  3IGY B;  3UN2 A;  5DLW A;  4LRC A;  5LQQ A;  1N2L A;  1HJK A;  3Q3Q A;  1ZEB A;  4QAX A;  2W5R A;  3DYC A;  1ALJ A;  4LRE A;  3TX0 A;  4KJD A;  2GSN A;  3MK1 A;  1ZEF A;  1EW9 A;  3E2D A;  5GOV A;  4MY4 A;  2W8S A;  4TN0 A;  4CXS A;  2W5T A;  1AJB A;  1ANI A;  2G9Y A;  3MK2 A;  1URA A;  1ED9 A;  4GTZ A;  3UO0 A;  5TJ3 A;  3NVL A;  4NWX A;  1KH5 A;  1EW8 A;  4GTX A;  4YR1 A;  5L0K A;  5L0B A;  1B8J A;  1Y7A A;  4GTY A;  4MIV A;  1EJJ A;  2RH6 A;  1ZED A;  3BDF A;  3T00 A;  4ZG7 A;  2W5S A;  5L0E A;  3BDG A;  5INH A;  4LRD A;  5EGH A;  4UPH A;  3A52 A;  2D1G A;  3BDG B;  2GA3 A;  3NKO A;  3NKM A;  1SHN A;  1E33 P;  1HQA A;  2GSU A;  3B5Q A;  5LIA A;  3WAW A;  1KH9 A;  2ANH A;  1O98 A;  1ANJ A;  2W5V A;  5DLT A;  1SHQ A;  4UOR A;  4UPL A;  2VQR A;  4UOO A;  2GSO A;  1KHN A;  3SZY A;  4NWJ A;  3NKN A;  3IDD A;  3SZZ A;  3TWZ A;  3DPC A;  4LR2 A;  4CYS A;  1KHK A;  1EW2 A;  5AJ9 A;  3WBH A;  2XR9 A;  5LRM A;  1AJA A;  3T01 A;  5HRT A;  1ELY A;  4ZG6 A;  4GTW A;  3MK0 A;  2XRG A;  3ED4 A;  1URB A;  3NKR A;  1ELX A;  1O99 A;  5GRR A;  2W8D A;  2W5W A;  4CXK A;  4LR8 A;  1P49 A;  4MHX A;  1EQJ A;  1KH4 A;  1AUK A;  4UPI A;  2GLQ A;  2W5Q A;  5KXA A;  1HDH A;  3M8W A;  3UN3 A;  4LR7 A;  4B56 A;  1ELZ A;  2X98 A;  3NKP A;  1AJD A;  4LRA A;  5IJQ A;  1ALI A;  3WAY A;  4CYR A;  1KH7 A;  4KAV A;  3T02 A;  4ZGA A;  4ZG9 A;  3OT9 A;  5DLV A;  1ALH A;  3UNY A;  4N7T A;  1ALK A;  1E1Z P;  4KAY A;  3CMR A;  2W5X A;  4LRB A;  5EGE A;  2QZU A;  4KM4 A;  1N2K A;  3KD8 A;  3M8Y A;  3LXQ A;  4KJG A;  3WAX A;  3WAV A;  3BDH A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1ELZA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations