1ELZ | Genus

Total Genus 157

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	157
Knots found	KnotProt 2.0: S +3₁
sequence length	449
structure length	449
Chain Sequence	TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDGAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5cfb147a56e559ced255c098/pdb.gz

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The Resolver thinks Pdb

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Time for openFile(/file/5cfb147a56e559ced255c098/pdb.gz): 1834 ms

reading 449 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

449 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 36 ms

Adding embedded #jmolscript: select ({0:448});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102. pubmed doi rcsb
molecule keywords	ALKALINE PHOSPHATASE
molecule tags	Hydrolase
source organism	Escherichia coli
total genus	157
structure length	449
sequence length	449
chains with identical sequence	B
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	1998-02-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1elzA00

3NKMA 1AJBA 4LR7A 2GA3A 1AJDA 1ZEFA 2ZKTA 1KHJA 4LRBA 4LRDA 2W5SA 1E1ZP 4GTWA 3IGZB 1KH5A 3B5QA 1ALKA 1E33P 3NKOA 1AJAA 3NVLA 4LQYA 5HRTA 4UOOA 2W5QA 2G9YA 5L0EA 2W5TA 4ZG9A 2GSUA 3IGYB 1ELYA 3OT9A 1EW8A 3MK1A 4N7TA 4MIVA 5LIAA 5DLTA 5LRMA 4LR2A 3M7VA 5EGHA 1ALHA 2GSOA 4GTYA 3TX0A 4YR1A 1ELXA 5IJSA 3WBHA 3UN5A 3TWZA 4KAVA 4KM4A 5DLWA 4UPKA 3NKNA 1EQJA 5L0BA 3UNYA 4QAXA 1ANJA 2IFYA 1AUKA 1P49A 1ZEBA 1E3CP 2RH6A 5IJQA 3T00A 2D1GA 1HQAA 2W5XA 3BDFA 3MK2A 2W8DA 5AJ9A 3KD8A 4UPHA 4FDIA 1ELZA 3SZYA 2X98A 3M8YA 3NKRA 1KH9A 2XRGA 3SZZA 1HDHA 4CXKA 1AJCA 1URBA 3WAVA 4KJDA 2GLQA 4LRFA 2IUCA 4FDJA 4MHXA 2VQRA 3A52A 1KHKA 3BDHA 1HJKA 4UOPA 1EI6A 4CYSA 1SHNA 1Y7AA 5EGEA 4LRCA 4MY4A 1O99A 1EW2A 4ZG7A 3M8ZA 4KJGA 3T02A 3DPCA 4UORA 1ALIA 4UPLA 4B56A 5C66A 5DLVA 1ED8A 3BDGA 1KHNA 2QZUA 1Y6VA 3E2DA 1O98A 4LRAA 1KH4A 1N2KA 4LR8A 3ED4A 1EJJA 3M8WA 3Q3QA 5GOVA 1ED9A 4ZGAA 3UO0A 1N2LA 3NKQA 4CXUA 5TJ3A 3WAXA 1KHLA 2IUCB 2W8SA 5INHA 1B8JA 1FSUA 3T01A 2XR9A 4TN0A 1K7HA 1KH7A 4GTZA 5GRRA 1ALJA 3WAWA 1ANIA 1ZEDA 2W5RA 4ZG6A 3UN3A 4CXSA 4LR9A 4UPIA 4GTXA 4LREA 1SHQA 3TG0A 3IDDA 5L0KA 1URAA 3LXQA 3DYCA 5KXAA 3BDGB 2GSNA 4KAYA 1EW9A 5K4PA 3MK0A 3UN2A 5LRNA 2W5VA 3WAYA 3NKPA 2W5WA 4NWXA 2ANHA 3CMRA 4CYRA 5LQQA 4NWJA 1E2SP
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3NKM A;  1AJB A;  4LR7 A;  2GA3 A;  1AJD A;  1ZEF A;  2ZKT A;  1KHJ A;  4LRB A;  4LRD A;  2W5S A;  1E1Z P;  4GTW A;  3IGZ B;  1KH5 A;  3B5Q A;  1ALK A;  1E33 P;  3NKO A;  1AJA A;  3NVL A;  4LQY A;  5HRT A;  4UOO A;  2W5Q A;  2G9Y A;  5L0E A;  2W5T A;  4ZG9 A;  2GSU A;  3IGY B;  1ELY A;  3OT9 A;  1EW8 A;  3MK1 A;  4N7T A;  4MIV A;  5LIA A;  5DLT A;  5LRM A;  4LR2 A;  3M7V A;  5EGH A;  1ALH A;  2GSO A;  4GTY A;  3TX0 A;  4YR1 A;  1ELX A;  5IJS A;  3WBH A;  3UN5 A;  3TWZ A;  4KAV A;  4KM4 A;  5DLW A;  4UPK A;  3NKN A;  1EQJ A;  5L0B A;  3UNY A;  4QAX A;  1ANJ A;  2IFY A;  1AUK A;  1P49 A;  1ZEB A;  1E3C P;  2RH6 A;  5IJQ A;  3T00 A;  2D1G A;  1HQA A;  2W5X A;  3BDF A;  3MK2 A;  2W8D A;  5AJ9 A;  3KD8 A;  4UPH A;  4FDI A;  1ELZ A;  3SZY A;  2X98 A;  3M8Y A;  3NKR A;  1KH9 A;  2XRG A;  3SZZ A;  1HDH A;  4CXK A;  1AJC A;  1URB A;  3WAV A;  4KJD A;  2GLQ A;  4LRF A;  2IUC A;  4FDJ A;  4MHX A;  2VQR A;  3A52 A;  1KHK A;  3BDH A;  1HJK A;  4UOP A;  1EI6 A;  4CYS A;  1SHN A;  1Y7A A;  5EGE A;  4LRC A;  4MY4 A;  1O99 A;  1EW2 A;  4ZG7 A;  3M8Z A;  4KJG A;  3T02 A;  3DPC A;  4UOR A;  1ALI A;  4UPL A;  4B56 A;  5C66 A;  5DLV A;  1ED8 A;  3BDG A;  1KHN A;  2QZU A;  1Y6V A;  3E2D A;  1O98 A;  4LRA A;  1KH4 A;  1N2K A;  4LR8 A;  3ED4 A;  1EJJ A;  3M8W A;  3Q3Q A;  5GOV A;  1ED9 A;  4ZGA A;  3UO0 A;  1N2L A;  3NKQ A;  4CXU A;  5TJ3 A;  3WAX A;  1KHL A;  2IUC B;  2W8S A;  5INH A;  1B8J A;  1FSU A;  3T01 A;  2XR9 A;  4TN0 A;  1K7H A;  1KH7 A;  4GTZ A;  5GRR A;  1ALJ A;  3WAW A;  1ANI A;  1ZED A;  2W5R A;  4ZG6 A;  3UN3 A;  4CXS A;  4LR9 A;  4UPI A;  4GTX A;  4LRE A;  1SHQ A;  3TG0 A;  3IDD A;  5L0K A;  1URA A;  3LXQ A;  3DYC A;  5KXA A;  3BDG B;  2GSN A;  4KAY A;  1EW9 A;  5K4P A;  3MK0 A;  3UN2 A;  5LRN A;  2W5V A;  3WAY A;  3NKP A;  2W5W A;  4NWX A;  2ANH A;  3CMR A;  4CYR A;  5LQQ A;  4NWJ A;  1E2S P; 
#chains in the Genus database with same CATH topology
 3NKM A;  1AJB A;  4LR7 A;  2GA3 A;  1AJD A;  1ZEF A;  2ZKT A;  1KHJ A;  4LRB A;  4LRD A;  2W5S A;  1E1Z P;  4GTW A;  3IGZ B;  1KH5 A;  3B5Q A;  1ALK A;  1E33 P;  3NKO A;  1AJA A;  3NVL A;  4LQY A;  5HRT A;  4UOO A;  2W5Q A;  2G9Y A;  5L0E A;  2W5T A;  4ZG9 A;  2GSU A;  3IGY B;  1ELY A;  3OT9 A;  1EW8 A;  3MK1 A;  4N7T A;  4MIV A;  5LIA A;  5DLT A;  5LRM A;  4LR2 A;  3M7V A;  5EGH A;  1ALH A;  2GSO A;  4GTY A;  3TX0 A;  4YR1 A;  1ELX A;  5IJS A;  3WBH A;  3UN5 A;  3TWZ A;  4KAV A;  4KM4 A;  5DLW A;  4UPK A;  3NKN A;  1EQJ A;  5L0B A;  3UNY A;  4QAX A;  1ANJ A;  2IFY A;  1AUK A;  1P49 A;  1ZEB A;  1E3C P;  2RH6 A;  5IJQ A;  3T00 A;  2D1G A;  1HQA A;  2W5X A;  3BDF A;  3MK2 A;  2W8D A;  5AJ9 A;  3KD8 A;  4UPH A;  4FDI A;  1ELZ A;  3SZY A;  2X98 A;  3M8Y A;  3NKR A;  1KH9 A;  2XRG A;  3SZZ A;  1HDH A;  4CXK A;  1AJC A;  1URB A;  3WAV A;  4KJD A;  2GLQ A;  4LRF A;  2IUC A;  4FDJ A;  4MHX A;  2VQR A;  3A52 A;  1KHK A;  3BDH A;  1HJK A;  4UOP A;  1EI6 A;  4CYS A;  1SHN A;  1Y7A A;  5EGE A;  4LRC A;  4MY4 A;  1O99 A;  1EW2 A;  4ZG7 A;  3M8Z A;  4KJG A;  3T02 A;  3DPC A;  4UOR A;  1ALI A;  4UPL A;  4B56 A;  5C66 A;  5DLV A;  1ED8 A;  3BDG A;  1KHN A;  2QZU A;  1Y6V A;  3E2D A;  1O98 A;  4LRA A;  1KH4 A;  1N2K A;  4LR8 A;  3ED4 A;  1EJJ A;  3M8W A;  3Q3Q A;  5GOV A;  1ED9 A;  4ZGA A;  3UO0 A;  1N2L A;  3NKQ A;  4CXU A;  5TJ3 A;  3WAX A;  1KHL A;  2IUC B;  2W8S A;  5INH A;  1B8J A;  1FSU A;  3T01 A;  2XR9 A;  4TN0 A;  1K7H A;  1KH7 A;  4GTZ A;  5GRR A;  1ALJ A;  3WAW A;  1ANI A;  1ZED A;  2W5R A;  4ZG6 A;  3UN3 A;  4CXS A;  4LR9 A;  4UPI A;  4GTX A;  4LRE A;  1SHQ A;  3TG0 A;  3IDD A;  5L0K A;  1URA A;  3LXQ A;  3DYC A;  5KXA A;  3BDG B;  2GSN A;  4KAY A;  1EW9 A;  5K4P A;  3MK0 A;  3UN2 A;  5LRN A;  2W5V A;  3WAY A;  3NKP A;  2W5W A;  4NWX A;  2ANH A;  3CMR A;  4CYR A;  5LQQ A;  4NWJ A;  1E2S P; 
#chains in the Genus database with same CATH homology
 3NKM A;  1AJB A;  4LR7 A;  2GA3 A;  1AJD A;  1ZEF A;  2ZKT A;  1KHJ A;  4LRB A;  4LRD A;  2W5S A;  1E1Z P;  4GTW A;  3IGZ B;  1KH5 A;  3B5Q A;  1ALK A;  1E33 P;  3NKO A;  1AJA A;  3NVL A;  4LQY A;  5HRT A;  4UOO A;  2W5Q A;  2G9Y A;  5L0E A;  2W5T A;  4ZG9 A;  2GSU A;  3IGY B;  1ELY A;  3OT9 A;  1EW8 A;  3MK1 A;  4N7T A;  4MIV A;  5LIA A;  5DLT A;  5LRM A;  4LR2 A;  3M7V A;  5EGH A;  1ALH A;  2GSO A;  4GTY A;  3TX0 A;  4YR1 A;  1ELX A;  5IJS A;  3WBH A;  3UN5 A;  3TWZ A;  4KAV A;  4KM4 A;  5DLW A;  4UPK A;  3NKN A;  1EQJ A;  5L0B A;  3UNY A;  4QAX A;  1ANJ A;  2IFY A;  1AUK A;  1P49 A;  1ZEB A;  1E3C P;  2RH6 A;  5IJQ A;  3T00 A;  2D1G A;  1HQA A;  2W5X A;  3BDF A;  3MK2 A;  2W8D A;  5AJ9 A;  3KD8 A;  4UPH A;  4FDI A;  1ELZ A;  3SZY A;  2X98 A;  3M8Y A;  3NKR A;  1KH9 A;  2XRG A;  3SZZ A;  1HDH A;  4CXK A;  1AJC A;  1URB A;  3WAV A;  4KJD A;  2GLQ A;  4LRF A;  2IUC A;  4FDJ A;  4MHX A;  2VQR A;  3A52 A;  1KHK A;  3BDH A;  1HJK A;  4UOP A;  1EI6 A;  4CYS A;  1SHN A;  1Y7A A;  5EGE A;  4LRC A;  4MY4 A;  1O99 A;  1EW2 A;  4ZG7 A;  3M8Z A;  4KJG A;  3T02 A;  3DPC A;  4UOR A;  1ALI A;  4UPL A;  4B56 A;  5C66 A;  5DLV A;  1ED8 A;  3BDG A;  1KHN A;  2QZU A;  1Y6V A;  3E2D A;  1O98 A;  4LRA A;  1KH4 A;  1N2K A;  4LR8 A;  3ED4 A;  1EJJ A;  3M8W A;  3Q3Q A;  5GOV A;  1ED9 A;  4ZGA A;  3UO0 A;  1N2L A;  3NKQ A;  4CXU A;  5TJ3 A;  3WAX A;  1KHL A;  2IUC B;  2W8S A;  5INH A;  1B8J A;  1FSU A;  3T01 A;  2XR9 A;  4TN0 A;  1K7H A;  1KH7 A;  4GTZ A;  5GRR A;  1ALJ A;  3WAW A;  1ANI A;  1ZED A;  2W5R A;  4ZG6 A;  3UN3 A;  4CXS A;  4LR9 A;  4UPI A;  4GTX A;  4LRE A;  1SHQ A;  3TG0 A;  3IDD A;  5L0K A;  1URA A;  3LXQ A;  3DYC A;  5KXA A;  3BDG B;  2GSN A;  4KAY A;  1EW9 A;  5K4P A;  3MK0 A;  3UN2 A;  5LRN A;  2W5V A;  3WAY A;  3NKP A;  2W5W A;  4NWX A;  2ANH A;  3CMR A;  4CYR A;  5LQQ A;  4NWJ A;  1E2S P;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1ELZA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations