1K7H | Genus

Total Genus 188

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	188
Knots found	KnotProt 2.0: S +3₁
sequence length	476
structure length	476
Chain Sequence	EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIANTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSATHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Hydrolase
publication title	The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase pubmed doi rcsb
molecule keywords	ALKALINE PHOSPHATASE
total genus	188
structure length	476
sequence length	476
chains with identical sequence	B
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	2001-10-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1k7hA00

3DPCA 2W5TA 4LR2A 3KD8A 5LRNA 2W5RA 3LXQA 5GOVA 2GA3A 1E2SP 1ED9A 1URBA 3NVLA 4UPIA 3T01A 2W5SA 1ZEFA 4UOOA 1HDHA 1KH7A 4CYRA 3TWZA 1HQAA 3UO0A 1ALJA 4KM4A 4LRCA 3IGYB 2IUCB 2W5VA 3BDGA 3MK0A 1Y7AA 2GSNA 1KHNA 1ZEDA 4UPHA 5AJ9A 3UNYA 2IFYA 1E1ZP 3NKQA 4LR9A 3MK1A 2X98A 3WAVA 1AJBA 1KH9A 4CXUA 2W5WA 3WAXA 2ZKTA 3T00A 3TG0A 3BDHA 1N2LA 3NKNA 4MIVA 2W5XA 5IJSA 3T02A 1B8JA 3SZZA 5C66A 3NKPA 5INHA 1ALIA 3UN3A 4KJDA 4MHXA 3M7VA 1SHNA 4N7TA 5DLWA 3WBHA 4GTZA 3NKRA 5L0EA 3UN5A 3DYCA 5LRMA 2QZUA 4LRBA 2GSOA 3TX0A 1ELZA 1KH5A 4NWXA 3IGZB 5IJQA 3ED4A 2RH6A 1HJKA 4UPKA 1EI6A 5DLTA 4ZGAA 1AJDA 5GRRA 4TN0A 2XRGA 1ANIA 4FDJA 5EGEA 3OT9A 1AJCA 2G9YA 1ZEBA 1Y6VA 1E3CP 4ZG9A 3SZYA 4KAYA 2XR9A 1EJJA 4KJGA 2D1GA 3M8YA 5KXAA 3CMRA 3IDDA 1EQJA 4UOPA 2W8DA 1KHLA 1EW2A 4LR8A 5LQQA 1N2KA 4UPLA 3A52A 1SHQA 1FSUA 1ED8A 4CXSA 1EW9A 3NKOA 1ELXA 1ELYA 4MY4A 4YR1A 3UN2A 4NWJA 1AJAA 2ANHA 2W8SA 1URAA 2W5QA 5TJ3A 2IUCA 4GTWA 1O98A 4LREA 2GSUA 4UORA 5DLVA 3Q3QA 4GTXA 4LRAA 4ZG6A 4ZG7A 3E2DA 5K4PA 3MK2A 2VQRA 1EW8A 5L0BA 4FDIA 3BDFA 4GTYA 4LRDA 1AUKA 4KAVA 4CXKA 1KH4A 4LQYA 5L0KA 1ALHA 3B5QA 3M8WA 3NKMA 1KHKA 1O99A 1E33P 3BDGB 5LIAA 1KHJA 1ANJA 5EGHA 5HRTA 1ALKA 3WAYA 4LR7A 3M8ZA 3WAWA 1P49A 4QAXA 1K7HA 4CYSA 4B56A 4LRFA 2GLQA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3DPC A;  2W5T A;  4LR2 A;  3KD8 A;  5LRN A;  2W5R A;  3LXQ A;  5GOV A;  2GA3 A;  1E2S P;  1ED9 A;  1URB A;  3NVL A;  4UPI A;  3T01 A;  2W5S A;  1ZEF A;  4UOO A;  1HDH A;  1KH7 A;  4CYR A;  3TWZ A;  1HQA A;  3UO0 A;  1ALJ A;  4KM4 A;  4LRC A;  3IGY B;  2IUC B;  2W5V A;  3BDG A;  3MK0 A;  1Y7A A;  2GSN A;  1KHN A;  1ZED A;  4UPH A;  5AJ9 A;  3UNY A;  2IFY A;  1E1Z P;  3NKQ A;  4LR9 A;  3MK1 A;  2X98 A;  3WAV A;  1AJB A;  1KH9 A;  4CXU A;  2W5W A;  3WAX A;  2ZKT A;  3T00 A;  3TG0 A;  3BDH A;  1N2L A;  3NKN A;  4MIV A;  2W5X A;  5IJS A;  3T02 A;  1B8J A;  3SZZ A;  5C66 A;  3NKP A;  5INH A;  1ALI A;  3UN3 A;  4KJD A;  4MHX A;  3M7V A;  1SHN A;  4N7T A;  5DLW A;  3WBH A;  4GTZ A;  3NKR A;  5L0E A;  3UN5 A;  3DYC A;  5LRM A;  2QZU A;  4LRB A;  2GSO A;  3TX0 A;  1ELZ A;  1KH5 A;  4NWX A;  3IGZ B;  5IJQ A;  3ED4 A;  2RH6 A;  1HJK A;  4UPK A;  1EI6 A;  5DLT A;  4ZGA A;  1AJD A;  5GRR A;  4TN0 A;  2XRG A;  1ANI A;  4FDJ A;  5EGE A;  3OT9 A;  1AJC A;  2G9Y A;  1ZEB A;  1Y6V A;  1E3C P;  4ZG9 A;  3SZY A;  4KAY A;  2XR9 A;  1EJJ A;  4KJG A;  2D1G A;  3M8Y A;  5KXA A;  3CMR A;  3IDD A;  1EQJ A;  4UOP A;  2W8D A;  1KHL A;  1EW2 A;  4LR8 A;  5LQQ A;  1N2K A;  4UPL A;  3A52 A;  1SHQ A;  1FSU A;  1ED8 A;  4CXS A;  1EW9 A;  3NKO A;  1ELX A;  1ELY A;  4MY4 A;  4YR1 A;  3UN2 A;  4NWJ A;  1AJA A;  2ANH A;  2W8S A;  1URA A;  2W5Q A;  5TJ3 A;  2IUC A;  4GTW A;  1O98 A;  4LRE A;  2GSU A;  4UOR A;  5DLV A;  3Q3Q A;  4GTX A;  4LRA A;  4ZG6 A;  4ZG7 A;  3E2D A;  5K4P A;  3MK2 A;  2VQR A;  1EW8 A;  5L0B A;  4FDI A;  3BDF A;  4GTY A;  4LRD A;  1AUK A;  4KAV A;  4CXK A;  1KH4 A;  4LQY A;  5L0K A;  1ALH A;  3B5Q A;  3M8W A;  3NKM A;  1KHK A;  1O99 A;  1E33 P;  3BDG B;  5LIA A;  1KHJ A;  1ANJ A;  5EGH A;  5HRT A;  1ALK A;  3WAY A;  4LR7 A;  3M8Z A;  3WAW A;  1P49 A;  4QAX A;  1K7H A;  4CYS A;  4B56 A;  4LRF A;  2GLQ A; 
#chains in the Genus database with same CATH topology
 3DPC A;  2W5T A;  4LR2 A;  3KD8 A;  5LRN A;  2W5R A;  3LXQ A;  5GOV A;  2GA3 A;  1E2S P;  1ED9 A;  1URB A;  3NVL A;  4UPI A;  3T01 A;  2W5S A;  1ZEF A;  4UOO A;  1HDH A;  1KH7 A;  4CYR A;  3TWZ A;  1HQA A;  3UO0 A;  1ALJ A;  4KM4 A;  4LRC A;  3IGY B;  2IUC B;  2W5V A;  3BDG A;  3MK0 A;  1Y7A A;  2GSN A;  1KHN A;  1ZED A;  4UPH A;  5AJ9 A;  3UNY A;  2IFY A;  1E1Z P;  3NKQ A;  4LR9 A;  3MK1 A;  2X98 A;  3WAV A;  1AJB A;  1KH9 A;  4CXU A;  2W5W A;  3WAX A;  2ZKT A;  3T00 A;  3TG0 A;  3BDH A;  1N2L A;  3NKN A;  4MIV A;  2W5X A;  5IJS A;  3T02 A;  1B8J A;  3SZZ A;  5C66 A;  3NKP A;  5INH A;  1ALI A;  3UN3 A;  4KJD A;  4MHX A;  3M7V A;  1SHN A;  4N7T A;  5DLW A;  3WBH A;  4GTZ A;  3NKR A;  5L0E A;  3UN5 A;  3DYC A;  5LRM A;  2QZU A;  4LRB A;  2GSO A;  3TX0 A;  1ELZ A;  1KH5 A;  4NWX A;  3IGZ B;  5IJQ A;  3ED4 A;  2RH6 A;  1HJK A;  4UPK A;  1EI6 A;  5DLT A;  4ZGA A;  1AJD A;  5GRR A;  4TN0 A;  2XRG A;  1ANI A;  4FDJ A;  5EGE A;  3OT9 A;  1AJC A;  2G9Y A;  1ZEB A;  1Y6V A;  1E3C P;  4ZG9 A;  3SZY A;  4KAY A;  2XR9 A;  1EJJ A;  4KJG A;  2D1G A;  3M8Y A;  5KXA A;  3CMR A;  3IDD A;  1EQJ A;  4UOP A;  2W8D A;  1KHL A;  1EW2 A;  4LR8 A;  5LQQ A;  1N2K A;  4UPL A;  3A52 A;  1SHQ A;  1FSU A;  1ED8 A;  4CXS A;  1EW9 A;  3NKO A;  1ELX A;  1ELY A;  4MY4 A;  4YR1 A;  3UN2 A;  4NWJ A;  1AJA A;  2ANH A;  2W8S A;  1URA A;  2W5Q A;  5TJ3 A;  2IUC A;  4GTW A;  1O98 A;  4LRE A;  2GSU A;  4UOR A;  5DLV A;  3Q3Q A;  4GTX A;  4LRA A;  4ZG6 A;  4ZG7 A;  3E2D A;  5K4P A;  3MK2 A;  2VQR A;  1EW8 A;  5L0B A;  4FDI A;  3BDF A;  4GTY A;  4LRD A;  1AUK A;  4KAV A;  4CXK A;  1KH4 A;  4LQY A;  5L0K A;  1ALH A;  3B5Q A;  3M8W A;  3NKM A;  1KHK A;  1O99 A;  1E33 P;  3BDG B;  5LIA A;  1KHJ A;  1ANJ A;  5EGH A;  5HRT A;  1ALK A;  3WAY A;  4LR7 A;  3M8Z A;  3WAW A;  1P49 A;  4QAX A;  1K7H A;  4CYS A;  4B56 A;  4LRF A;  2GLQ A; 
#chains in the Genus database with same CATH homology
 3DPC A;  2W5T A;  4LR2 A;  3KD8 A;  5LRN A;  2W5R A;  3LXQ A;  5GOV A;  2GA3 A;  1E2S P;  1ED9 A;  1URB A;  3NVL A;  4UPI A;  3T01 A;  2W5S A;  1ZEF A;  4UOO A;  1HDH A;  1KH7 A;  4CYR A;  3TWZ A;  1HQA A;  3UO0 A;  1ALJ A;  4KM4 A;  4LRC A;  3IGY B;  2IUC B;  2W5V A;  3BDG A;  3MK0 A;  1Y7A A;  2GSN A;  1KHN A;  1ZED A;  4UPH A;  5AJ9 A;  3UNY A;  2IFY A;  1E1Z P;  3NKQ A;  4LR9 A;  3MK1 A;  2X98 A;  3WAV A;  1AJB A;  1KH9 A;  4CXU A;  2W5W A;  3WAX A;  2ZKT A;  3T00 A;  3TG0 A;  3BDH A;  1N2L A;  3NKN A;  4MIV A;  2W5X A;  5IJS A;  3T02 A;  1B8J A;  3SZZ A;  5C66 A;  3NKP A;  5INH A;  1ALI A;  3UN3 A;  4KJD A;  4MHX A;  3M7V A;  1SHN A;  4N7T A;  5DLW A;  3WBH A;  4GTZ A;  3NKR A;  5L0E A;  3UN5 A;  3DYC A;  5LRM A;  2QZU A;  4LRB A;  2GSO A;  3TX0 A;  1ELZ A;  1KH5 A;  4NWX A;  3IGZ B;  5IJQ A;  3ED4 A;  2RH6 A;  1HJK A;  4UPK A;  1EI6 A;  5DLT A;  4ZGA A;  1AJD A;  5GRR A;  4TN0 A;  2XRG A;  1ANI A;  4FDJ A;  5EGE A;  3OT9 A;  1AJC A;  2G9Y A;  1ZEB A;  1Y6V A;  1E3C P;  4ZG9 A;  3SZY A;  4KAY A;  2XR9 A;  1EJJ A;  4KJG A;  2D1G A;  3M8Y A;  5KXA A;  3CMR A;  3IDD A;  1EQJ A;  4UOP A;  2W8D A;  1KHL A;  1EW2 A;  4LR8 A;  5LQQ A;  1N2K A;  4UPL A;  3A52 A;  1SHQ A;  1FSU A;  1ED8 A;  4CXS A;  1EW9 A;  3NKO A;  1ELX A;  1ELY A;  4MY4 A;  4YR1 A;  3UN2 A;  4NWJ A;  1AJA A;  2ANH A;  2W8S A;  1URA A;  2W5Q A;  5TJ3 A;  2IUC A;  4GTW A;  1O98 A;  4LRE A;  2GSU A;  4UOR A;  5DLV A;  3Q3Q A;  4GTX A;  4LRA A;  4ZG6 A;  4ZG7 A;  3E2D A;  5K4P A;  3MK2 A;  2VQR A;  1EW8 A;  5L0B A;  4FDI A;  3BDF A;  4GTY A;  4LRD A;  1AUK A;  4KAV A;  4CXK A;  1KH4 A;  4LQY A;  5L0K A;  1ALH A;  3B5Q A;  3M8W A;  3NKM A;  1KHK A;  1O99 A;  1E33 P;  3BDG B;  5LIA A;  1KHJ A;  1ANJ A;  5EGH A;  5HRT A;  1ALK A;  3WAY A;  4LR7 A;  3M8Z A;  3WAW A;  1P49 A;  4QAX A;  1K7H A;  4CYS A;  4B56 A;  4LRF A;  2GLQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1K7HA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations