1K7HA

Crystal structure of shrimp alkaline phosphatase
Total Genus 188
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
188
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIANTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSATHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ALKALINE PHOSPHATASE
total genus 188
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2001-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1k7hA00
3IGZB 3T01A 4KAYA 5LQQA 2W5WA 3DYCA 5EGHA 1ZEBA 3ED4A 4GTYA 5DLWA 1Y7AA 2W5TA 3B5QA 1E2SP 1E1ZP 3MK1A 3TX0A 3A52A 1AJCA 5IJQA 1AJDA 4CXUA 3WAWA 3SZZA 1N2LA 4NWXA 3NKNA 1KH4A 4CYSA 4NWJA 3WBHA 2IUCA 1ED9A 3TWZA 1HDHA 4LRFA 4LRDA 4MY4A 5IJSA 5LRNA 4KAVA 5L0BA 4LQYA 4CXKA 1B8JA 1KH9A 1N2KA 2W8SA 4UPIA 3M7VA 3T00A 5DLTA 2IUCB 4FDIA 4TN0A 4UOOA 3WAVA 2XRGA 3T02A 4GTXA 2W5RA 5GOVA 4UPHA 3NKRA 3NKQA 5GRRA 4ZG6A 4ZG9A 3WAYA 2XR9A 1KHLA 3M8YA 3UO0A 4LR8A 3UN2A 3WAXA 4KM4A 5LRMA 4YR1A 2GA3A 2ANHA 4KJGA 5LIAA 2W5VA 3NKMA 4LR7A 1P49A 3KD8A 1ELZA 4GTWA 1ELXA 1HQAA 1SHQA 1ZEFA 2RH6A 4ZG7A 1O99A 2G9YA 2GLQA 1K7HA 5KXAA 5HRTA 4LR2A 4UPLA 4MHXA 3BDFA 3MK0A 1EI6A 4CYRA 3M8ZA 3UN3A 4LRCA 1EW8A 4UOPA 3UNYA 2W5QA 2X98A 4LRAA 1ED8A 5TJ3A 1HJKA 4UPKA 3IGYB 1ALIA 1ALKA 4LRBA 3BDHA 4MIVA 4ZGAA 1KHJA 3Q3QA 1URAA 1URBA 2GSOA 5L0KA 1KH7A 5AJ9A 1FSUA 4KJDA 1EJJA 3LXQA 3DPCA 2W5XA 3NKPA 4FDJA 4B56A 1AJBA 2QZUA 3TG0A 4CXSA 5L0EA 3UN5A 2D1GA 1KHKA 3CMRA 2ZKTA 1KH5A 1EQJA 5EGEA 5INHA 3NVLA 1O98A 1AUKA 3BDGA 1AJAA 1EW2A 4N7TA 1ANIA 1ALHA 4GTZA 4UORA 3OT9A 4LREA 3SZYA 1Y6VA 2VQRA 1ANJA 5C66A 3E2DA 2GSUA 3IDDA 3BDGB 2W8DA 1SHNA 3NKOA 4QAXA 5DLVA 1ELYA 1ALJA 3MK2A 1KHNA 2GSNA 3M8WA 2IFYA 4LR9A 1E3CP 2W5SA 1EW9A 1E33P 5K4PA 1ZEDA
chains in the Genus database with same CATH superfamily
3IGZB 3T01A 4KAYA 5LQQA 2W5WA 3DYCA 5EGHA 1ZEBA 3ED4A 4GTYA 5DLWA 1Y7AA 2W5TA 3B5QA 1E2SP 1E1ZP 3MK1A 3TX0A 3A52A 1AJCA 5IJQA 1AJDA 4CXUA 3WAWA 3SZZA 1N2LA 4NWXA 3NKNA 1KH4A 4CYSA 4NWJA 3WBHA 2IUCA 1ED9A 3TWZA 1HDHA 4LRFA 4LRDA 4MY4A 5IJSA 5LRNA 4KAVA 5L0BA 4LQYA 4CXKA 1B8JA 1KH9A 1N2KA 2W8SA 4UPIA 3M7VA 3T00A 5DLTA 2IUCB 4FDIA 4TN0A 4UOOA 3WAVA 2XRGA 3T02A 4GTXA 2W5RA 5GOVA 4UPHA 3NKRA 3NKQA 5GRRA 4ZG6A 4ZG9A 3WAYA 2XR9A 1KHLA 3M8YA 3UO0A 4LR8A 3UN2A 3WAXA 4KM4A 5LRMA 4YR1A 2GA3A 2ANHA 4KJGA 5LIAA 2W5VA 3NKMA 4LR7A 1P49A 3KD8A 1ELZA 4GTWA 1ELXA 1HQAA 1SHQA 1ZEFA 2RH6A 4ZG7A 1O99A 2G9YA 2GLQA 1K7HA 5KXAA 5HRTA 4LR2A 4UPLA 4MHXA 3BDFA 3MK0A 1EI6A 4CYRA 3M8ZA 3UN3A 4LRCA 1EW8A 4UOPA 3UNYA 2W5QA 2X98A 4LRAA 1ED8A 5TJ3A 1HJKA 4UPKA 3IGYB 1ALIA 1ALKA 4LRBA 3BDHA 4MIVA 4ZGAA 1KHJA 3Q3QA 1URAA 1URBA 2GSOA 5L0KA 1KH7A 5AJ9A 1FSUA 4KJDA 1EJJA 3LXQA 3DPCA 2W5XA 3NKPA 4FDJA 4B56A 1AJBA 2QZUA 3TG0A 4CXSA 5L0EA 3UN5A 2D1GA 1KHKA 3CMRA 2ZKTA 1KH5A 1EQJA 5EGEA 5INHA 3NVLA 1O98A 1AUKA 3BDGA 1AJAA 1EW2A 4N7TA 1ANIA 1ALHA 4GTZA 4UORA 3OT9A 4LREA 3SZYA 1Y6VA 2VQRA 1ANJA 5C66A 3E2DA 2GSUA 3IDDA 3BDGB 2W8DA 1SHNA 3NKOA 4QAXA 5DLVA 1ELYA 1ALJA 3MK2A 1KHNA 2GSNA 3M8WA 2IFYA 4LR9A 1E3CP 2W5SA 1EW9A 1E33P 5K4PA 1ZEDA
chains in the Genus database with same CATH topology
3IGZB 3T01A 4KAYA 5LQQA 2W5WA 3DYCA 5EGHA 1ZEBA 3ED4A 4GTYA 5DLWA 1Y7AA 2W5TA 3B5QA 1E2SP 1E1ZP 3MK1A 3TX0A 3A52A 1AJCA 5IJQA 1AJDA 4CXUA 3WAWA 3SZZA 1N2LA 4NWXA 3NKNA 1KH4A 4CYSA 4NWJA 3WBHA 2IUCA 1ED9A 3TWZA 1HDHA 4LRFA 4LRDA 4MY4A 5IJSA 5LRNA 4KAVA 5L0BA 4LQYA 4CXKA 1B8JA 1KH9A 1N2KA 2W8SA 4UPIA 3M7VA 3T00A 5DLTA 2IUCB 4FDIA 4TN0A 4UOOA 3WAVA 2XRGA 3T02A 4GTXA 2W5RA 5GOVA 4UPHA 3NKRA 3NKQA 5GRRA 4ZG6A 4ZG9A 3WAYA 2XR9A 1KHLA 3M8YA 3UO0A 4LR8A 3UN2A 3WAXA 4KM4A 5LRMA 4YR1A 2GA3A 2ANHA 4KJGA 5LIAA 2W5VA 3NKMA 4LR7A 1P49A 3KD8A 1ELZA 4GTWA 1ELXA 1HQAA 1SHQA 1ZEFA 2RH6A 4ZG7A 1O99A 2G9YA 2GLQA 1K7HA 5KXAA 5HRTA 4LR2A 4UPLA 4MHXA 3BDFA 3MK0A 1EI6A 4CYRA 3M8ZA 3UN3A 4LRCA 1EW8A 4UOPA 3UNYA 2W5QA 2X98A 4LRAA 1ED8A 5TJ3A 1HJKA 4UPKA 3IGYB 1ALIA 1ALKA 4LRBA 3BDHA 4MIVA 4ZGAA 1KHJA 3Q3QA 1URAA 1URBA 2GSOA 5L0KA 1KH7A 5AJ9A 1FSUA 4KJDA 1EJJA 3LXQA 3DPCA 2W5XA 3NKPA 4FDJA 4B56A 1AJBA 2QZUA 3TG0A 4CXSA 5L0EA 3UN5A 2D1GA 1KHKA 3CMRA 2ZKTA 1KH5A 1EQJA 5EGEA 5INHA 3NVLA 1O98A 1AUKA 3BDGA 1AJAA 1EW2A 4N7TA 1ANIA 1ALHA 4GTZA 4UORA 3OT9A 4LREA 3SZYA 1Y6VA 2VQRA 1ANJA 5C66A 3E2DA 2GSUA 3IDDA 3BDGB 2W8DA 1SHNA 3NKOA 4QAXA 5DLVA 1ELYA 1ALJA 3MK2A 1KHNA 2GSNA 3M8WA 2IFYA 4LR9A 1E3CP 2W5SA 1EW9A 1E33P 5K4PA 1ZEDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IGZ B;  3T01 A;  4KAY A;  5LQQ A;  2W5W A;  3DYC A;  5EGH A;  1ZEB A;  3ED4 A;  4GTY A;  5DLW A;  1Y7A A;  2W5T A;  3B5Q A;  1E2S P;  1E1Z P;  3MK1 A;  3TX0 A;  3A52 A;  1AJC A;  5IJQ A;  1AJD A;  4CXU A;  3WAW A;  3SZZ A;  1N2L A;  4NWX A;  3NKN A;  1KH4 A;  4CYS A;  4NWJ A;  3WBH A;  2IUC A;  1ED9 A;  3TWZ A;  1HDH A;  4LRF A;  4LRD A;  4MY4 A;  5IJS A;  5LRN A;  4KAV A;  5L0B A;  4LQY A;  4CXK A;  1B8J A;  1KH9 A;  1N2K A;  2W8S A;  4UPI A;  3M7V A;  3T00 A;  5DLT A;  2IUC B;  4FDI A;  4TN0 A;  4UOO A;  3WAV A;  2XRG A;  3T02 A;  4GTX A;  2W5R A;  5GOV A;  4UPH A;  3NKR A;  3NKQ A;  5GRR A;  4ZG6 A;  4ZG9 A;  3WAY A;  2XR9 A;  1KHL A;  3M8Y A;  3UO0 A;  4LR8 A;  3UN2 A;  3WAX A;  4KM4 A;  5LRM A;  4YR1 A;  2GA3 A;  2ANH A;  4KJG A;  5LIA A;  2W5V A;  3NKM A;  4LR7 A;  1P49 A;  3KD8 A;  1ELZ A;  4GTW A;  1ELX A;  1HQA A;  1SHQ A;  1ZEF A;  2RH6 A;  4ZG7 A;  1O99 A;  2G9Y A;  2GLQ A;  1K7H A;  5KXA A;  5HRT A;  4LR2 A;  4UPL A;  4MHX A;  3BDF A;  3MK0 A;  1EI6 A;  4CYR A;  3M8Z A;  3UN3 A;  4LRC A;  1EW8 A;  4UOP A;  3UNY A;  2W5Q A;  2X98 A;  4LRA A;  1ED8 A;  5TJ3 A;  1HJK A;  4UPK A;  3IGY B;  1ALI A;  1ALK A;  4LRB A;  3BDH A;  4MIV A;  4ZGA A;  1KHJ A;  3Q3Q A;  1URA A;  1URB A;  2GSO A;  5L0K A;  1KH7 A;  5AJ9 A;  1FSU A;  4KJD A;  1EJJ A;  3LXQ A;  3DPC A;  2W5X A;  3NKP A;  4FDJ A;  4B56 A;  1AJB A;  2QZU A;  3TG0 A;  4CXS A;  5L0E A;  3UN5 A;  2D1G A;  1KHK A;  3CMR A;  2ZKT A;  1KH5 A;  1EQJ A;  5EGE A;  5INH A;  3NVL A;  1O98 A;  1AUK A;  3BDG A;  1AJA A;  1EW2 A;  4N7T A;  1ANI A;  1ALH A;  4GTZ A;  4UOR A;  3OT9 A;  4LRE A;  3SZY A;  1Y6V A;  2VQR A;  1ANJ A;  5C66 A;  3E2D A;  2GSU A;  3IDD A;  3BDG B;  2W8D A;  1SHN A;  3NKO A;  4QAX A;  5DLV A;  1ELY A;  1ALJ A;  3MK2 A;  1KHN A;  2GSN A;  3M8W A;  2IFY A;  4LR9 A;  1E3C P;  2W5S A;  1EW9 A;  1E33 P;  5K4P A;  1ZED A; 
#chains in the Genus database with same CATH topology
 3IGZ B;  3T01 A;  4KAY A;  5LQQ A;  2W5W A;  3DYC A;  5EGH A;  1ZEB A;  3ED4 A;  4GTY A;  5DLW A;  1Y7A A;  2W5T A;  3B5Q A;  1E2S P;  1E1Z P;  3MK1 A;  3TX0 A;  3A52 A;  1AJC A;  5IJQ A;  1AJD A;  4CXU A;  3WAW A;  3SZZ A;  1N2L A;  4NWX A;  3NKN A;  1KH4 A;  4CYS A;  4NWJ A;  3WBH A;  2IUC A;  1ED9 A;  3TWZ A;  1HDH A;  4LRF A;  4LRD A;  4MY4 A;  5IJS A;  5LRN A;  4KAV A;  5L0B A;  4LQY A;  4CXK A;  1B8J A;  1KH9 A;  1N2K A;  2W8S A;  4UPI A;  3M7V A;  3T00 A;  5DLT A;  2IUC B;  4FDI A;  4TN0 A;  4UOO A;  3WAV A;  2XRG A;  3T02 A;  4GTX A;  2W5R A;  5GOV A;  4UPH A;  3NKR A;  3NKQ A;  5GRR A;  4ZG6 A;  4ZG9 A;  3WAY A;  2XR9 A;  1KHL A;  3M8Y A;  3UO0 A;  4LR8 A;  3UN2 A;  3WAX A;  4KM4 A;  5LRM A;  4YR1 A;  2GA3 A;  2ANH A;  4KJG A;  5LIA A;  2W5V A;  3NKM A;  4LR7 A;  1P49 A;  3KD8 A;  1ELZ A;  4GTW A;  1ELX A;  1HQA A;  1SHQ A;  1ZEF A;  2RH6 A;  4ZG7 A;  1O99 A;  2G9Y A;  2GLQ A;  1K7H A;  5KXA A;  5HRT A;  4LR2 A;  4UPL A;  4MHX A;  3BDF A;  3MK0 A;  1EI6 A;  4CYR A;  3M8Z A;  3UN3 A;  4LRC A;  1EW8 A;  4UOP A;  3UNY A;  2W5Q A;  2X98 A;  4LRA A;  1ED8 A;  5TJ3 A;  1HJK A;  4UPK A;  3IGY B;  1ALI A;  1ALK A;  4LRB A;  3BDH A;  4MIV A;  4ZGA A;  1KHJ A;  3Q3Q A;  1URA A;  1URB A;  2GSO A;  5L0K A;  1KH7 A;  5AJ9 A;  1FSU A;  4KJD A;  1EJJ A;  3LXQ A;  3DPC A;  2W5X A;  3NKP A;  4FDJ A;  4B56 A;  1AJB A;  2QZU A;  3TG0 A;  4CXS A;  5L0E A;  3UN5 A;  2D1G A;  1KHK A;  3CMR A;  2ZKT A;  1KH5 A;  1EQJ A;  5EGE A;  5INH A;  3NVL A;  1O98 A;  1AUK A;  3BDG A;  1AJA A;  1EW2 A;  4N7T A;  1ANI A;  1ALH A;  4GTZ A;  4UOR A;  3OT9 A;  4LRE A;  3SZY A;  1Y6V A;  2VQR A;  1ANJ A;  5C66 A;  3E2D A;  2GSU A;  3IDD A;  3BDG B;  2W8D A;  1SHN A;  3NKO A;  4QAX A;  5DLV A;  1ELY A;  1ALJ A;  3MK2 A;  1KHN A;  2GSN A;  3M8W A;  2IFY A;  4LR9 A;  1E3C P;  2W5S A;  1EW9 A;  1E33 P;  5K4P A;  1ZED A; 
#chains in the Genus database with same CATH homology
 3IGZ B;  3T01 A;  4KAY A;  5LQQ A;  2W5W A;  3DYC A;  5EGH A;  1ZEB A;  3ED4 A;  4GTY A;  5DLW A;  1Y7A A;  2W5T A;  3B5Q A;  1E2S P;  1E1Z P;  3MK1 A;  3TX0 A;  3A52 A;  1AJC A;  5IJQ A;  1AJD A;  4CXU A;  3WAW A;  3SZZ A;  1N2L A;  4NWX A;  3NKN A;  1KH4 A;  4CYS A;  4NWJ A;  3WBH A;  2IUC A;  1ED9 A;  3TWZ A;  1HDH A;  4LRF A;  4LRD A;  4MY4 A;  5IJS A;  5LRN A;  4KAV A;  5L0B A;  4LQY A;  4CXK A;  1B8J A;  1KH9 A;  1N2K A;  2W8S A;  4UPI A;  3M7V A;  3T00 A;  5DLT A;  2IUC B;  4FDI A;  4TN0 A;  4UOO A;  3WAV A;  2XRG A;  3T02 A;  4GTX A;  2W5R A;  5GOV A;  4UPH A;  3NKR A;  3NKQ A;  5GRR A;  4ZG6 A;  4ZG9 A;  3WAY A;  2XR9 A;  1KHL A;  3M8Y A;  3UO0 A;  4LR8 A;  3UN2 A;  3WAX A;  4KM4 A;  5LRM A;  4YR1 A;  2GA3 A;  2ANH A;  4KJG A;  5LIA A;  2W5V A;  3NKM A;  4LR7 A;  1P49 A;  3KD8 A;  1ELZ A;  4GTW A;  1ELX A;  1HQA A;  1SHQ A;  1ZEF A;  2RH6 A;  4ZG7 A;  1O99 A;  2G9Y A;  2GLQ A;  1K7H A;  5KXA A;  5HRT A;  4LR2 A;  4UPL A;  4MHX A;  3BDF A;  3MK0 A;  1EI6 A;  4CYR A;  3M8Z A;  3UN3 A;  4LRC A;  1EW8 A;  4UOP A;  3UNY A;  2W5Q A;  2X98 A;  4LRA A;  1ED8 A;  5TJ3 A;  1HJK A;  4UPK A;  3IGY B;  1ALI A;  1ALK A;  4LRB A;  3BDH A;  4MIV A;  4ZGA A;  1KHJ A;  3Q3Q A;  1URA A;  1URB A;  2GSO A;  5L0K A;  1KH7 A;  5AJ9 A;  1FSU A;  4KJD A;  1EJJ A;  3LXQ A;  3DPC A;  2W5X A;  3NKP A;  4FDJ A;  4B56 A;  1AJB A;  2QZU A;  3TG0 A;  4CXS A;  5L0E A;  3UN5 A;  2D1G A;  1KHK A;  3CMR A;  2ZKT A;  1KH5 A;  1EQJ A;  5EGE A;  5INH A;  3NVL A;  1O98 A;  1AUK A;  3BDG A;  1AJA A;  1EW2 A;  4N7T A;  1ANI A;  1ALH A;  4GTZ A;  4UOR A;  3OT9 A;  4LRE A;  3SZY A;  1Y6V A;  2VQR A;  1ANJ A;  5C66 A;  3E2D A;  2GSU A;  3IDD A;  3BDG B;  2W8D A;  1SHN A;  3NKO A;  4QAX A;  5DLV A;  1ELY A;  1ALJ A;  3MK2 A;  1KHN A;  2GSN A;  3M8W A;  2IFY A;  4LR9 A;  1E3C P;  2W5S A;  1EW9 A;  1E33 P;  5K4P A;  1ZED A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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