1SHNA

Crystal structure of shrimp alkaline phosphatase with phosphate bound
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords alkaline phosphatase
publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shnA00
1EI6A 4MY4A 4CYSA 2ANHA 5KXAA 3SZZA 3OT9A 1EW2A 4LR2A 4KM4A 4KAVA 3T02A 1KH7A 3WAVA 1ALIA 3UO0A 4N7TA 4GTZA 3NKMA 1AJCA 5AJ9A 3WAWA 1KHKA 5L0KA 2XR9A 1N2KA 3BDGB 3UN5A 4KJDA 3M8YA 4LRDA 2W5WA 1B8JA 5DLVA 3Q3QA 1FSUA 3SZYA 1Y6VA 1Y7AA 2IFYA 1URAA 4LR7A 4ZG6A 4CXSA 1SHQA 2GSNA 5LRNA 5DLTA 4YR1A 4LRCA 1ALHA 4LR9A 5INHA 4QAXA 2X98A 3IGZB 1EW8A 3NKRA 3E2DA 4LRBA 5EGHA 3UN2A 3TWZA 3MK2A 3WAYA 4MHXA 1ZEBA 4LRFA 3A52A 4MIVA 1E3CP 1ED9A 4UOOA 4UPKA 1EW9A 3TG0A 5L0BA 1ELZA 1O98A 4UPIA 1EQJA 1ZEDA 4FDIA 1ED8A 1ANIA 3T00A 3T01A 4GTXA 4UPLA 5LIAA 5L0EA 2GLQA 3BDGA 3ED4A 2G9YA 1SHNA 4ZG9A 4KAYA 5HRTA 1O99A 4CXUA 1KHJA 4GTWA 3CMRA 4NWJA 1ELXA 2W5RA 3BDFA 1E1ZP 1ZEFA 4LQYA 5GOVA 3NKOA 1HJKA 2GA3A 1ELYA 4LREA 4LRAA 4FDJA 5DLWA 1P49A 2ZKTA 2GSOA 3DPCA 2GSUA 3BDHA 1ANJA 2QZUA 3LXQA 4CXKA 2D1GA 3M7VA 4ZG7A 1ALJA 1E33P 5TJ3A 1HDHA 1AJBA 1AJAA 4UOPA 3MK0A 2W5TA 1N2LA 3IDDA 4UPHA 5C66A 3IGYB 2W5XA 3TX0A 1ALKA 4LR8A 1KH9A 4B56A 4TN0A 3M8WA 4KJGA 1E2SP 1EJJA 5IJQA 3NKNA 2W5QA 3UN3A 1AJDA 3KD8A 3WBHA 1KH5A 2W8DA 4UORA 5GRRA 3B5QA 4GTYA 5K4PA 5IJSA 3DYCA 1AUKA 3WAXA 3UNYA 1URBA 2W5VA 1KHNA 1HQAA 2W5SA 5EGEA 3MK1A 1KHLA 4ZGAA 4NWXA 2IUCB 2W8SA 3NKPA 2XRGA 2VQRA 1KH4A 5LQQA 2IUCA 1K7HA 2RH6A 3M8ZA 4CYRA 3NVLA 5LRMA 3NKQA
chains in the Genus database with same CATH superfamily
1EI6A 4MY4A 4CYSA 2ANHA 5KXAA 3SZZA 3OT9A 1EW2A 4LR2A 4KM4A 4KAVA 3T02A 1KH7A 3WAVA 1ALIA 3UO0A 4N7TA 4GTZA 3NKMA 1AJCA 5AJ9A 3WAWA 1KHKA 5L0KA 2XR9A 1N2KA 3BDGB 3UN5A 4KJDA 3M8YA 4LRDA 2W5WA 1B8JA 5DLVA 3Q3QA 1FSUA 3SZYA 1Y6VA 1Y7AA 2IFYA 1URAA 4LR7A 4ZG6A 4CXSA 1SHQA 2GSNA 5LRNA 5DLTA 4YR1A 4LRCA 1ALHA 4LR9A 5INHA 4QAXA 2X98A 3IGZB 1EW8A 3NKRA 3E2DA 4LRBA 5EGHA 3UN2A 3TWZA 3MK2A 3WAYA 4MHXA 1ZEBA 4LRFA 3A52A 4MIVA 1E3CP 1ED9A 4UOOA 4UPKA 1EW9A 3TG0A 5L0BA 1ELZA 1O98A 4UPIA 1EQJA 1ZEDA 4FDIA 1ED8A 1ANIA 3T00A 3T01A 4GTXA 4UPLA 5LIAA 5L0EA 2GLQA 3BDGA 3ED4A 2G9YA 1SHNA 4ZG9A 4KAYA 5HRTA 1O99A 4CXUA 1KHJA 4GTWA 3CMRA 4NWJA 1ELXA 2W5RA 3BDFA 1E1ZP 1ZEFA 4LQYA 5GOVA 3NKOA 1HJKA 2GA3A 1ELYA 4LREA 4LRAA 4FDJA 5DLWA 1P49A 2ZKTA 2GSOA 3DPCA 2GSUA 3BDHA 1ANJA 2QZUA 3LXQA 4CXKA 2D1GA 3M7VA 4ZG7A 1ALJA 1E33P 5TJ3A 1HDHA 1AJBA 1AJAA 4UOPA 3MK0A 2W5TA 1N2LA 3IDDA 4UPHA 5C66A 3IGYB 2W5XA 3TX0A 1ALKA 4LR8A 1KH9A 4B56A 4TN0A 3M8WA 4KJGA 1E2SP 1EJJA 5IJQA 3NKNA 2W5QA 3UN3A 1AJDA 3KD8A 3WBHA 1KH5A 2W8DA 4UORA 5GRRA 3B5QA 4GTYA 5K4PA 5IJSA 3DYCA 1AUKA 3WAXA 3UNYA 1URBA 2W5VA 1KHNA 1HQAA 2W5SA 5EGEA 3MK1A 1KHLA 4ZGAA 4NWXA 2IUCB 2W8SA 3NKPA 2XRGA 2VQRA 1KH4A 5LQQA 2IUCA 1K7HA 2RH6A 3M8ZA 4CYRA 3NVLA 5LRMA 3NKQA
chains in the Genus database with same CATH topology
1EI6A 4MY4A 4CYSA 2ANHA 5KXAA 3SZZA 3OT9A 1EW2A 4LR2A 4KM4A 4KAVA 3T02A 1KH7A 3WAVA 1ALIA 3UO0A 4N7TA 4GTZA 3NKMA 1AJCA 5AJ9A 3WAWA 1KHKA 5L0KA 2XR9A 1N2KA 3BDGB 3UN5A 4KJDA 3M8YA 4LRDA 2W5WA 1B8JA 5DLVA 3Q3QA 1FSUA 3SZYA 1Y6VA 1Y7AA 2IFYA 1URAA 4LR7A 4ZG6A 4CXSA 1SHQA 2GSNA 5LRNA 5DLTA 4YR1A 4LRCA 1ALHA 4LR9A 5INHA 4QAXA 2X98A 3IGZB 1EW8A 3NKRA 3E2DA 4LRBA 5EGHA 3UN2A 3TWZA 3MK2A 3WAYA 4MHXA 1ZEBA 4LRFA 3A52A 4MIVA 1E3CP 1ED9A 4UOOA 4UPKA 1EW9A 3TG0A 5L0BA 1ELZA 1O98A 4UPIA 1EQJA 1ZEDA 4FDIA 1ED8A 1ANIA 3T00A 3T01A 4GTXA 4UPLA 5LIAA 5L0EA 2GLQA 3BDGA 3ED4A 2G9YA 1SHNA 4ZG9A 4KAYA 5HRTA 1O99A 4CXUA 1KHJA 4GTWA 3CMRA 4NWJA 1ELXA 2W5RA 3BDFA 1E1ZP 1ZEFA 4LQYA 5GOVA 3NKOA 1HJKA 2GA3A 1ELYA 4LREA 4LRAA 4FDJA 5DLWA 1P49A 2ZKTA 2GSOA 3DPCA 2GSUA 3BDHA 1ANJA 2QZUA 3LXQA 4CXKA 2D1GA 3M7VA 4ZG7A 1ALJA 1E33P 5TJ3A 1HDHA 1AJBA 1AJAA 4UOPA 3MK0A 2W5TA 1N2LA 3IDDA 4UPHA 5C66A 3IGYB 2W5XA 3TX0A 1ALKA 4LR8A 1KH9A 4B56A 4TN0A 3M8WA 4KJGA 1E2SP 1EJJA 5IJQA 3NKNA 2W5QA 3UN3A 1AJDA 3KD8A 3WBHA 1KH5A 2W8DA 4UORA 5GRRA 3B5QA 4GTYA 5K4PA 5IJSA 3DYCA 1AUKA 3WAXA 3UNYA 1URBA 2W5VA 1KHNA 1HQAA 2W5SA 5EGEA 3MK1A 1KHLA 4ZGAA 4NWXA 2IUCB 2W8SA 3NKPA 2XRGA 2VQRA 1KH4A 5LQQA 2IUCA 1K7HA 2RH6A 3M8ZA 4CYRA 3NVLA 5LRMA 3NKQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EI6 A;  4MY4 A;  4CYS A;  2ANH A;  5KXA A;  3SZZ A;  3OT9 A;  1EW2 A;  4LR2 A;  4KM4 A;  4KAV A;  3T02 A;  1KH7 A;  3WAV A;  1ALI A;  3UO0 A;  4N7T A;  4GTZ A;  3NKM A;  1AJC A;  5AJ9 A;  3WAW A;  1KHK A;  5L0K A;  2XR9 A;  1N2K A;  3BDG B;  3UN5 A;  4KJD A;  3M8Y A;  4LRD A;  2W5W A;  1B8J A;  5DLV A;  3Q3Q A;  1FSU A;  3SZY A;  1Y6V A;  1Y7A A;  2IFY A;  1URA A;  4LR7 A;  4ZG6 A;  4CXS A;  1SHQ A;  2GSN A;  5LRN A;  5DLT A;  4YR1 A;  4LRC A;  1ALH A;  4LR9 A;  5INH A;  4QAX A;  2X98 A;  3IGZ B;  1EW8 A;  3NKR A;  3E2D A;  4LRB A;  5EGH A;  3UN2 A;  3TWZ A;  3MK2 A;  3WAY A;  4MHX A;  1ZEB A;  4LRF A;  3A52 A;  4MIV A;  1E3C P;  1ED9 A;  4UOO A;  4UPK A;  1EW9 A;  3TG0 A;  5L0B A;  1ELZ A;  1O98 A;  4UPI A;  1EQJ A;  1ZED A;  4FDI A;  1ED8 A;  1ANI A;  3T00 A;  3T01 A;  4GTX A;  4UPL A;  5LIA A;  5L0E A;  2GLQ A;  3BDG A;  3ED4 A;  2G9Y A;  1SHN A;  4ZG9 A;  4KAY A;  5HRT A;  1O99 A;  4CXU A;  1KHJ A;  4GTW A;  3CMR A;  4NWJ A;  1ELX A;  2W5R A;  3BDF A;  1E1Z P;  1ZEF A;  4LQY A;  5GOV A;  3NKO A;  1HJK A;  2GA3 A;  1ELY A;  4LRE A;  4LRA A;  4FDJ A;  5DLW A;  1P49 A;  2ZKT A;  2GSO A;  3DPC A;  2GSU A;  3BDH A;  1ANJ A;  2QZU A;  3LXQ A;  4CXK A;  2D1G A;  3M7V A;  4ZG7 A;  1ALJ A;  1E33 P;  5TJ3 A;  1HDH A;  1AJB A;  1AJA A;  4UOP A;  3MK0 A;  2W5T A;  1N2L A;  3IDD A;  4UPH A;  5C66 A;  3IGY B;  2W5X A;  3TX0 A;  1ALK A;  4LR8 A;  1KH9 A;  4B56 A;  4TN0 A;  3M8W A;  4KJG A;  1E2S P;  1EJJ A;  5IJQ A;  3NKN A;  2W5Q A;  3UN3 A;  1AJD A;  3KD8 A;  3WBH A;  1KH5 A;  2W8D A;  4UOR A;  5GRR A;  3B5Q A;  4GTY A;  5K4P A;  5IJS A;  3DYC A;  1AUK A;  3WAX A;  3UNY A;  1URB A;  2W5V A;  1KHN A;  1HQA A;  2W5S A;  5EGE A;  3MK1 A;  1KHL A;  4ZGA A;  4NWX A;  2IUC B;  2W8S A;  3NKP A;  2XRG A;  2VQR A;  1KH4 A;  5LQQ A;  2IUC A;  1K7H A;  2RH6 A;  3M8Z A;  4CYR A;  3NVL A;  5LRM A;  3NKQ A; 
#chains in the Genus database with same CATH topology
 1EI6 A;  4MY4 A;  4CYS A;  2ANH A;  5KXA A;  3SZZ A;  3OT9 A;  1EW2 A;  4LR2 A;  4KM4 A;  4KAV A;  3T02 A;  1KH7 A;  3WAV A;  1ALI A;  3UO0 A;  4N7T A;  4GTZ A;  3NKM A;  1AJC A;  5AJ9 A;  3WAW A;  1KHK A;  5L0K A;  2XR9 A;  1N2K A;  3BDG B;  3UN5 A;  4KJD A;  3M8Y A;  4LRD A;  2W5W A;  1B8J A;  5DLV A;  3Q3Q A;  1FSU A;  3SZY A;  1Y6V A;  1Y7A A;  2IFY A;  1URA A;  4LR7 A;  4ZG6 A;  4CXS A;  1SHQ A;  2GSN A;  5LRN A;  5DLT A;  4YR1 A;  4LRC A;  1ALH A;  4LR9 A;  5INH A;  4QAX A;  2X98 A;  3IGZ B;  1EW8 A;  3NKR A;  3E2D A;  4LRB A;  5EGH A;  3UN2 A;  3TWZ A;  3MK2 A;  3WAY A;  4MHX A;  1ZEB A;  4LRF A;  3A52 A;  4MIV A;  1E3C P;  1ED9 A;  4UOO A;  4UPK A;  1EW9 A;  3TG0 A;  5L0B A;  1ELZ A;  1O98 A;  4UPI A;  1EQJ A;  1ZED A;  4FDI A;  1ED8 A;  1ANI A;  3T00 A;  3T01 A;  4GTX A;  4UPL A;  5LIA A;  5L0E A;  2GLQ A;  3BDG A;  3ED4 A;  2G9Y A;  1SHN A;  4ZG9 A;  4KAY A;  5HRT A;  1O99 A;  4CXU A;  1KHJ A;  4GTW A;  3CMR A;  4NWJ A;  1ELX A;  2W5R A;  3BDF A;  1E1Z P;  1ZEF A;  4LQY A;  5GOV A;  3NKO A;  1HJK A;  2GA3 A;  1ELY A;  4LRE A;  4LRA A;  4FDJ A;  5DLW A;  1P49 A;  2ZKT A;  2GSO A;  3DPC A;  2GSU A;  3BDH A;  1ANJ A;  2QZU A;  3LXQ A;  4CXK A;  2D1G A;  3M7V A;  4ZG7 A;  1ALJ A;  1E33 P;  5TJ3 A;  1HDH A;  1AJB A;  1AJA A;  4UOP A;  3MK0 A;  2W5T A;  1N2L A;  3IDD A;  4UPH A;  5C66 A;  3IGY B;  2W5X A;  3TX0 A;  1ALK A;  4LR8 A;  1KH9 A;  4B56 A;  4TN0 A;  3M8W A;  4KJG A;  1E2S P;  1EJJ A;  5IJQ A;  3NKN A;  2W5Q A;  3UN3 A;  1AJD A;  3KD8 A;  3WBH A;  1KH5 A;  2W8D A;  4UOR A;  5GRR A;  3B5Q A;  4GTY A;  5K4P A;  5IJS A;  3DYC A;  1AUK A;  3WAX A;  3UNY A;  1URB A;  2W5V A;  1KHN A;  1HQA A;  2W5S A;  5EGE A;  3MK1 A;  1KHL A;  4ZGA A;  4NWX A;  2IUC B;  2W8S A;  3NKP A;  2XRG A;  2VQR A;  1KH4 A;  5LQQ A;  2IUC A;  1K7H A;  2RH6 A;  3M8Z A;  4CYR A;  3NVL A;  5LRM A;  3NKQ A; 
#chains in the Genus database with same CATH homology
 1EI6 A;  4MY4 A;  4CYS A;  2ANH A;  5KXA A;  3SZZ A;  3OT9 A;  1EW2 A;  4LR2 A;  4KM4 A;  4KAV A;  3T02 A;  1KH7 A;  3WAV A;  1ALI A;  3UO0 A;  4N7T A;  4GTZ A;  3NKM A;  1AJC A;  5AJ9 A;  3WAW A;  1KHK A;  5L0K A;  2XR9 A;  1N2K A;  3BDG B;  3UN5 A;  4KJD A;  3M8Y A;  4LRD A;  2W5W A;  1B8J A;  5DLV A;  3Q3Q A;  1FSU A;  3SZY A;  1Y6V A;  1Y7A A;  2IFY A;  1URA A;  4LR7 A;  4ZG6 A;  4CXS A;  1SHQ A;  2GSN A;  5LRN A;  5DLT A;  4YR1 A;  4LRC A;  1ALH A;  4LR9 A;  5INH A;  4QAX A;  2X98 A;  3IGZ B;  1EW8 A;  3NKR A;  3E2D A;  4LRB A;  5EGH A;  3UN2 A;  3TWZ A;  3MK2 A;  3WAY A;  4MHX A;  1ZEB A;  4LRF A;  3A52 A;  4MIV A;  1E3C P;  1ED9 A;  4UOO A;  4UPK A;  1EW9 A;  3TG0 A;  5L0B A;  1ELZ A;  1O98 A;  4UPI A;  1EQJ A;  1ZED A;  4FDI A;  1ED8 A;  1ANI A;  3T00 A;  3T01 A;  4GTX A;  4UPL A;  5LIA A;  5L0E A;  2GLQ A;  3BDG A;  3ED4 A;  2G9Y A;  1SHN A;  4ZG9 A;  4KAY A;  5HRT A;  1O99 A;  4CXU A;  1KHJ A;  4GTW A;  3CMR A;  4NWJ A;  1ELX A;  2W5R A;  3BDF A;  1E1Z P;  1ZEF A;  4LQY A;  5GOV A;  3NKO A;  1HJK A;  2GA3 A;  1ELY A;  4LRE A;  4LRA A;  4FDJ A;  5DLW A;  1P49 A;  2ZKT A;  2GSO A;  3DPC A;  2GSU A;  3BDH A;  1ANJ A;  2QZU A;  3LXQ A;  4CXK A;  2D1G A;  3M7V A;  4ZG7 A;  1ALJ A;  1E33 P;  5TJ3 A;  1HDH A;  1AJB A;  1AJA A;  4UOP A;  3MK0 A;  2W5T A;  1N2L A;  3IDD A;  4UPH A;  5C66 A;  3IGY B;  2W5X A;  3TX0 A;  1ALK A;  4LR8 A;  1KH9 A;  4B56 A;  4TN0 A;  3M8W A;  4KJG A;  1E2S P;  1EJJ A;  5IJQ A;  3NKN A;  2W5Q A;  3UN3 A;  1AJD A;  3KD8 A;  3WBH A;  1KH5 A;  2W8D A;  4UOR A;  5GRR A;  3B5Q A;  4GTY A;  5K4P A;  5IJS A;  3DYC A;  1AUK A;  3WAX A;  3UNY A;  1URB A;  2W5V A;  1KHN A;  1HQA A;  2W5S A;  5EGE A;  3MK1 A;  1KHL A;  4ZGA A;  4NWX A;  2IUC B;  2W8S A;  3NKP A;  2XRG A;  2VQR A;  1KH4 A;  5LQQ A;  2IUC A;  1K7H A;  2RH6 A;  3M8Z A;  4CYR A;  3NVL A;  5LRM A;  3NKQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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