1SHQA

Crystal structure of shrimp alkaline phosphatase with magnesium in m3
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords alkaline phosphatase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shqA00
1KH5A 5LQQA 4LRAA 3M8WA 4LR8A 5EGEA 5IJQA 2ANHA 4LRFA 3SZYA 3WBHA 3CMRA 3TG0A 3KD8A 1HDHA 4LRBA 1ALHA 3A52A 3WAWA 2W5RA 5GRRA 1ED9A 4KM4A 2GSUA 1ZEBA 4KJDA 1ELYA 4UORA 4ZG6A 1FSUA 2XR9A 5AJ9A 5LRMA 4MY4A 1HQAA 2VQRA 1N2KA 3NVLA 4LR9A 3T00A 1EI6A 1EW8A 3NKOA 3UN2A 4CYSA 1E3CP 2IUCA 3BDGB 3WAXA 1ZEFA 2W5QA 3UN5A 4KJGA 1Y6VA 1ANJA 3TWZA 3IDDA 1KH7A 2W8SA 4FDJA 2D1GA 3M8YA 4GTXA 4UPIA 4CXUA 4B56A 4ZG7A 4LR7A 1KHKA 4MIVA 4UOPA 4ZGAA 4LRCA 3B5QA 3DPCA 3T02A 4ZG9A 1EW9A 5GOVA 2W8DA 3BDFA 5IJSA 1AJAA 5KXAA 2IFYA 3OT9A 2GLQA 3E2DA 1AJDA 1SHNA 3WAYA 4LREA 1URBA 4KAVA 5L0EA 2XRGA 2X98A 5K4PA 4LRDA 3Q3QA 4UPLA 5C66A 2RH6A 1EQJA 2IUCB 4NWJA 1AUKA 2ZKTA 1URAA 2GSNA 3IGYB 2GA3A 4UPHA 3WAVA 2W5VA 1KHNA 3M7VA 3NKNA 1E1ZP 4GTZA 5INHA 5LIAA 1AJBA 4LQYA 2G9YA 4NWXA 4CXSA 1ZEDA 3NKRA 1ALIA 2GSOA 4GTYA 4UPKA 4YR1A 1KHJA 3MK1A 5L0BA 1ED8A 3DYCA 2W5SA 4N7TA 1O98A 4KAYA 1ANIA 1ALJA 1EW2A 4LR2A 1E33P 4MHXA 4UOOA 2W5TA 3BDGA 5EGHA 1B8JA 5DLWA 5L0KA 5DLTA 4QAXA 3NKMA 5DLVA 1O99A 1EJJA 1P49A 1HJKA 4GTWA 5HRTA 3SZZA 1ELXA 1ALKA 3LXQA 3IGZB 1Y7AA 3M8ZA 4CYRA 3MK0A 3UN3A 3TX0A 4TN0A 2W5XA 2QZUA 5TJ3A 1ELZA 3UNYA 5LRNA 4FDIA 3BDHA 1K7HA 3ED4A 1SHQA 1E2SP 3T01A 1N2LA 4CXKA 3MK2A 3NKQA 3NKPA 3UO0A 1AJCA 1KHLA 1KH4A 2W5WA 1KH9A
chains in the Genus database with same CATH superfamily
1KH5A 5LQQA 4LRAA 3M8WA 4LR8A 5EGEA 5IJQA 2ANHA 4LRFA 3SZYA 3WBHA 3CMRA 3TG0A 3KD8A 1HDHA 4LRBA 1ALHA 3A52A 3WAWA 2W5RA 5GRRA 1ED9A 4KM4A 2GSUA 1ZEBA 4KJDA 1ELYA 4UORA 4ZG6A 1FSUA 2XR9A 5AJ9A 5LRMA 4MY4A 1HQAA 2VQRA 1N2KA 3NVLA 4LR9A 3T00A 1EI6A 1EW8A 3NKOA 3UN2A 4CYSA 1E3CP 2IUCA 3BDGB 3WAXA 1ZEFA 2W5QA 3UN5A 4KJGA 1Y6VA 1ANJA 3TWZA 3IDDA 1KH7A 2W8SA 4FDJA 2D1GA 3M8YA 4GTXA 4UPIA 4CXUA 4B56A 4ZG7A 4LR7A 1KHKA 4MIVA 4UOPA 4ZGAA 4LRCA 3B5QA 3DPCA 3T02A 4ZG9A 1EW9A 5GOVA 2W8DA 3BDFA 5IJSA 1AJAA 5KXAA 2IFYA 3OT9A 2GLQA 3E2DA 1AJDA 1SHNA 3WAYA 4LREA 1URBA 4KAVA 5L0EA 2XRGA 2X98A 5K4PA 4LRDA 3Q3QA 4UPLA 5C66A 2RH6A 1EQJA 2IUCB 4NWJA 1AUKA 2ZKTA 1URAA 2GSNA 3IGYB 2GA3A 4UPHA 3WAVA 2W5VA 1KHNA 3M7VA 3NKNA 1E1ZP 4GTZA 5INHA 5LIAA 1AJBA 4LQYA 2G9YA 4NWXA 4CXSA 1ZEDA 3NKRA 1ALIA 2GSOA 4GTYA 4UPKA 4YR1A 1KHJA 3MK1A 5L0BA 1ED8A 3DYCA 2W5SA 4N7TA 1O98A 4KAYA 1ANIA 1ALJA 1EW2A 4LR2A 1E33P 4MHXA 4UOOA 2W5TA 3BDGA 5EGHA 1B8JA 5DLWA 5L0KA 5DLTA 4QAXA 3NKMA 5DLVA 1O99A 1EJJA 1P49A 1HJKA 4GTWA 5HRTA 3SZZA 1ELXA 1ALKA 3LXQA 3IGZB 1Y7AA 3M8ZA 4CYRA 3MK0A 3UN3A 3TX0A 4TN0A 2W5XA 2QZUA 5TJ3A 1ELZA 3UNYA 5LRNA 4FDIA 3BDHA 1K7HA 3ED4A 1SHQA 1E2SP 3T01A 1N2LA 4CXKA 3MK2A 3NKQA 3NKPA 3UO0A 1AJCA 1KHLA 1KH4A 2W5WA 1KH9A
chains in the Genus database with same CATH topology
1KH5A 5LQQA 4LRAA 3M8WA 4LR8A 5EGEA 5IJQA 2ANHA 4LRFA 3SZYA 3WBHA 3CMRA 3TG0A 3KD8A 1HDHA 4LRBA 1ALHA 3A52A 3WAWA 2W5RA 5GRRA 1ED9A 4KM4A 2GSUA 1ZEBA 4KJDA 1ELYA 4UORA 4ZG6A 1FSUA 2XR9A 5AJ9A 5LRMA 4MY4A 1HQAA 2VQRA 1N2KA 3NVLA 4LR9A 3T00A 1EI6A 1EW8A 3NKOA 3UN2A 4CYSA 1E3CP 2IUCA 3BDGB 3WAXA 1ZEFA 2W5QA 3UN5A 4KJGA 1Y6VA 1ANJA 3TWZA 3IDDA 1KH7A 2W8SA 4FDJA 2D1GA 3M8YA 4GTXA 4UPIA 4CXUA 4B56A 4ZG7A 4LR7A 1KHKA 4MIVA 4UOPA 4ZGAA 4LRCA 3B5QA 3DPCA 3T02A 4ZG9A 1EW9A 5GOVA 2W8DA 3BDFA 5IJSA 1AJAA 5KXAA 2IFYA 3OT9A 2GLQA 3E2DA 1AJDA 1SHNA 3WAYA 4LREA 1URBA 4KAVA 5L0EA 2XRGA 2X98A 5K4PA 4LRDA 3Q3QA 4UPLA 5C66A 2RH6A 1EQJA 2IUCB 4NWJA 1AUKA 2ZKTA 1URAA 2GSNA 3IGYB 2GA3A 4UPHA 3WAVA 2W5VA 1KHNA 3M7VA 3NKNA 1E1ZP 4GTZA 5INHA 5LIAA 1AJBA 4LQYA 2G9YA 4NWXA 4CXSA 1ZEDA 3NKRA 1ALIA 2GSOA 4GTYA 4UPKA 4YR1A 1KHJA 3MK1A 5L0BA 1ED8A 3DYCA 2W5SA 4N7TA 1O98A 4KAYA 1ANIA 1ALJA 1EW2A 4LR2A 1E33P 4MHXA 4UOOA 2W5TA 3BDGA 5EGHA 1B8JA 5DLWA 5L0KA 5DLTA 4QAXA 3NKMA 5DLVA 1O99A 1EJJA 1P49A 1HJKA 4GTWA 5HRTA 3SZZA 1ELXA 1ALKA 3LXQA 3IGZB 1Y7AA 3M8ZA 4CYRA 3MK0A 3UN3A 3TX0A 4TN0A 2W5XA 2QZUA 5TJ3A 1ELZA 3UNYA 5LRNA 4FDIA 3BDHA 1K7HA 3ED4A 1SHQA 1E2SP 3T01A 1N2LA 4CXKA 3MK2A 3NKQA 3NKPA 3UO0A 1AJCA 1KHLA 1KH4A 2W5WA 1KH9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KH5 A;  5LQQ A;  4LRA A;  3M8W A;  4LR8 A;  5EGE A;  5IJQ A;  2ANH A;  4LRF A;  3SZY A;  3WBH A;  3CMR A;  3TG0 A;  3KD8 A;  1HDH A;  4LRB A;  1ALH A;  3A52 A;  3WAW A;  2W5R A;  5GRR A;  1ED9 A;  4KM4 A;  2GSU A;  1ZEB A;  4KJD A;  1ELY A;  4UOR A;  4ZG6 A;  1FSU A;  2XR9 A;  5AJ9 A;  5LRM A;  4MY4 A;  1HQA A;  2VQR A;  1N2K A;  3NVL A;  4LR9 A;  3T00 A;  1EI6 A;  1EW8 A;  3NKO A;  3UN2 A;  4CYS A;  1E3C P;  2IUC A;  3BDG B;  3WAX A;  1ZEF A;  2W5Q A;  3UN5 A;  4KJG A;  1Y6V A;  1ANJ A;  3TWZ A;  3IDD A;  1KH7 A;  2W8S A;  4FDJ A;  2D1G A;  3M8Y A;  4GTX A;  4UPI A;  4CXU A;  4B56 A;  4ZG7 A;  4LR7 A;  1KHK A;  4MIV A;  4UOP A;  4ZGA A;  4LRC A;  3B5Q A;  3DPC A;  3T02 A;  4ZG9 A;  1EW9 A;  5GOV A;  2W8D A;  3BDF A;  5IJS A;  1AJA A;  5KXA A;  2IFY A;  3OT9 A;  2GLQ A;  3E2D A;  1AJD A;  1SHN A;  3WAY A;  4LRE A;  1URB A;  4KAV A;  5L0E A;  2XRG A;  2X98 A;  5K4P A;  4LRD A;  3Q3Q A;  4UPL A;  5C66 A;  2RH6 A;  1EQJ A;  2IUC B;  4NWJ A;  1AUK A;  2ZKT A;  1URA A;  2GSN A;  3IGY B;  2GA3 A;  4UPH A;  3WAV A;  2W5V A;  1KHN A;  3M7V A;  3NKN A;  1E1Z P;  4GTZ A;  5INH A;  5LIA A;  1AJB A;  4LQY A;  2G9Y A;  4NWX A;  4CXS A;  1ZED A;  3NKR A;  1ALI A;  2GSO A;  4GTY A;  4UPK A;  4YR1 A;  1KHJ A;  3MK1 A;  5L0B A;  1ED8 A;  3DYC A;  2W5S A;  4N7T A;  1O98 A;  4KAY A;  1ANI A;  1ALJ A;  1EW2 A;  4LR2 A;  1E33 P;  4MHX A;  4UOO A;  2W5T A;  3BDG A;  5EGH A;  1B8J A;  5DLW A;  5L0K A;  5DLT A;  4QAX A;  3NKM A;  5DLV A;  1O99 A;  1EJJ A;  1P49 A;  1HJK A;  4GTW A;  5HRT A;  3SZZ A;  1ELX A;  1ALK A;  3LXQ A;  3IGZ B;  1Y7A A;  3M8Z A;  4CYR A;  3MK0 A;  3UN3 A;  3TX0 A;  4TN0 A;  2W5X A;  2QZU A;  5TJ3 A;  1ELZ A;  3UNY A;  5LRN A;  4FDI A;  3BDH A;  1K7H A;  3ED4 A;  1SHQ A;  1E2S P;  3T01 A;  1N2L A;  4CXK A;  3MK2 A;  3NKQ A;  3NKP A;  3UO0 A;  1AJC A;  1KHL A;  1KH4 A;  2W5W A;  1KH9 A; 
#chains in the Genus database with same CATH topology
 1KH5 A;  5LQQ A;  4LRA A;  3M8W A;  4LR8 A;  5EGE A;  5IJQ A;  2ANH A;  4LRF A;  3SZY A;  3WBH A;  3CMR A;  3TG0 A;  3KD8 A;  1HDH A;  4LRB A;  1ALH A;  3A52 A;  3WAW A;  2W5R A;  5GRR A;  1ED9 A;  4KM4 A;  2GSU A;  1ZEB A;  4KJD A;  1ELY A;  4UOR A;  4ZG6 A;  1FSU A;  2XR9 A;  5AJ9 A;  5LRM A;  4MY4 A;  1HQA A;  2VQR A;  1N2K A;  3NVL A;  4LR9 A;  3T00 A;  1EI6 A;  1EW8 A;  3NKO A;  3UN2 A;  4CYS A;  1E3C P;  2IUC A;  3BDG B;  3WAX A;  1ZEF A;  2W5Q A;  3UN5 A;  4KJG A;  1Y6V A;  1ANJ A;  3TWZ A;  3IDD A;  1KH7 A;  2W8S A;  4FDJ A;  2D1G A;  3M8Y A;  4GTX A;  4UPI A;  4CXU A;  4B56 A;  4ZG7 A;  4LR7 A;  1KHK A;  4MIV A;  4UOP A;  4ZGA A;  4LRC A;  3B5Q A;  3DPC A;  3T02 A;  4ZG9 A;  1EW9 A;  5GOV A;  2W8D A;  3BDF A;  5IJS A;  1AJA A;  5KXA A;  2IFY A;  3OT9 A;  2GLQ A;  3E2D A;  1AJD A;  1SHN A;  3WAY A;  4LRE A;  1URB A;  4KAV A;  5L0E A;  2XRG A;  2X98 A;  5K4P A;  4LRD A;  3Q3Q A;  4UPL A;  5C66 A;  2RH6 A;  1EQJ A;  2IUC B;  4NWJ A;  1AUK A;  2ZKT A;  1URA A;  2GSN A;  3IGY B;  2GA3 A;  4UPH A;  3WAV A;  2W5V A;  1KHN A;  3M7V A;  3NKN A;  1E1Z P;  4GTZ A;  5INH A;  5LIA A;  1AJB A;  4LQY A;  2G9Y A;  4NWX A;  4CXS A;  1ZED A;  3NKR A;  1ALI A;  2GSO A;  4GTY A;  4UPK A;  4YR1 A;  1KHJ A;  3MK1 A;  5L0B A;  1ED8 A;  3DYC A;  2W5S A;  4N7T A;  1O98 A;  4KAY A;  1ANI A;  1ALJ A;  1EW2 A;  4LR2 A;  1E33 P;  4MHX A;  4UOO A;  2W5T A;  3BDG A;  5EGH A;  1B8J A;  5DLW A;  5L0K A;  5DLT A;  4QAX A;  3NKM A;  5DLV A;  1O99 A;  1EJJ A;  1P49 A;  1HJK A;  4GTW A;  5HRT A;  3SZZ A;  1ELX A;  1ALK A;  3LXQ A;  3IGZ B;  1Y7A A;  3M8Z A;  4CYR A;  3MK0 A;  3UN3 A;  3TX0 A;  4TN0 A;  2W5X A;  2QZU A;  5TJ3 A;  1ELZ A;  3UNY A;  5LRN A;  4FDI A;  3BDH A;  1K7H A;  3ED4 A;  1SHQ A;  1E2S P;  3T01 A;  1N2L A;  4CXK A;  3MK2 A;  3NKQ A;  3NKP A;  3UO0 A;  1AJC A;  1KHL A;  1KH4 A;  2W5W A;  1KH9 A; 
#chains in the Genus database with same CATH homology
 1KH5 A;  5LQQ A;  4LRA A;  3M8W A;  4LR8 A;  5EGE A;  5IJQ A;  2ANH A;  4LRF A;  3SZY A;  3WBH A;  3CMR A;  3TG0 A;  3KD8 A;  1HDH A;  4LRB A;  1ALH A;  3A52 A;  3WAW A;  2W5R A;  5GRR A;  1ED9 A;  4KM4 A;  2GSU A;  1ZEB A;  4KJD A;  1ELY A;  4UOR A;  4ZG6 A;  1FSU A;  2XR9 A;  5AJ9 A;  5LRM A;  4MY4 A;  1HQA A;  2VQR A;  1N2K A;  3NVL A;  4LR9 A;  3T00 A;  1EI6 A;  1EW8 A;  3NKO A;  3UN2 A;  4CYS A;  1E3C P;  2IUC A;  3BDG B;  3WAX A;  1ZEF A;  2W5Q A;  3UN5 A;  4KJG A;  1Y6V A;  1ANJ A;  3TWZ A;  3IDD A;  1KH7 A;  2W8S A;  4FDJ A;  2D1G A;  3M8Y A;  4GTX A;  4UPI A;  4CXU A;  4B56 A;  4ZG7 A;  4LR7 A;  1KHK A;  4MIV A;  4UOP A;  4ZGA A;  4LRC A;  3B5Q A;  3DPC A;  3T02 A;  4ZG9 A;  1EW9 A;  5GOV A;  2W8D A;  3BDF A;  5IJS A;  1AJA A;  5KXA A;  2IFY A;  3OT9 A;  2GLQ A;  3E2D A;  1AJD A;  1SHN A;  3WAY A;  4LRE A;  1URB A;  4KAV A;  5L0E A;  2XRG A;  2X98 A;  5K4P A;  4LRD A;  3Q3Q A;  4UPL A;  5C66 A;  2RH6 A;  1EQJ A;  2IUC B;  4NWJ A;  1AUK A;  2ZKT A;  1URA A;  2GSN A;  3IGY B;  2GA3 A;  4UPH A;  3WAV A;  2W5V A;  1KHN A;  3M7V A;  3NKN A;  1E1Z P;  4GTZ A;  5INH A;  5LIA A;  1AJB A;  4LQY A;  2G9Y A;  4NWX A;  4CXS A;  1ZED A;  3NKR A;  1ALI A;  2GSO A;  4GTY A;  4UPK A;  4YR1 A;  1KHJ A;  3MK1 A;  5L0B A;  1ED8 A;  3DYC A;  2W5S A;  4N7T A;  1O98 A;  4KAY A;  1ANI A;  1ALJ A;  1EW2 A;  4LR2 A;  1E33 P;  4MHX A;  4UOO A;  2W5T A;  3BDG A;  5EGH A;  1B8J A;  5DLW A;  5L0K A;  5DLT A;  4QAX A;  3NKM A;  5DLV A;  1O99 A;  1EJJ A;  1P49 A;  1HJK A;  4GTW A;  5HRT A;  3SZZ A;  1ELX A;  1ALK A;  3LXQ A;  3IGZ B;  1Y7A A;  3M8Z A;  4CYR A;  3MK0 A;  3UN3 A;  3TX0 A;  4TN0 A;  2W5X A;  2QZU A;  5TJ3 A;  1ELZ A;  3UNY A;  5LRN A;  4FDI A;  3BDH A;  1K7H A;  3ED4 A;  1SHQ A;  1E2S P;  3T01 A;  1N2L A;  4CXK A;  3MK2 A;  3NKQ A;  3NKP A;  3UO0 A;  1AJC A;  1KHL A;  1KH4 A;  2W5W A;  1KH9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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