1SHQA

Crystal structure of shrimp alkaline phosphatase with magnesium in m3
Total Genus 187
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords alkaline phosphatase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shqA00
2W5QA 4FDIA 1EW2A 5DLVA 1AJAA 5KXAA 5L0BA 1ALJA 1KHJA 2W5SA 3NKMA 1O98A 2W5WA 5INHA 2IUCA 3BDHA 3E2DA 3A52A 3LXQA 2GLQA 4LREA 5LIAA 1ALKA 4LRFA 4TN0A 1O99A 2IUCB 1KH9A 5EGHA 4MY4A 4B56A 3TWZA 4LR2A 1EW8A 1Y6VA 3NVLA 4ZG7A 4KAVA 4ZG6A 2QZUA 3MK1A 2W5XA 3SZYA 2XRGA 4KJGA 3TX0A 3IGYB 3M8YA 3IGZB 2GSUA 3UNYA 1ALIA 1ZEBA 1KHLA 4LQYA 3NKQA 1K7HA 4UOPA 1EI6A 1EQJA 2W8DA 1HDHA 3KD8A 3Q3QA 4UPIA 3T02A 3NKPA 3UN2A 1ANIA 1AJDA 1B8JA 4LRCA 4CYRA 3WAVA 1ELZA 5DLTA 3WAWA 4LRDA 3M8ZA 1ED9A 4KJDA 4UOOA 4GTYA 4LRAA 2GA3A 4UORA 5K4PA 1ALHA 1KH7A 3SZZA 1E1ZP 1N2LA 3BDGA 5GOVA 1KH4A 3NKNA 2VQRA 1E3CP 4N7TA 4LR7A 1P49A 3DYCA 5AJ9A 4MHXA 2ANHA 3UN5A 5C66A 3WAYA 3BDGB 5LRNA 3UO0A 4GTZA 3UN3A 5GRRA 3TG0A 5LQQA 1ELYA 4LR8A 5HRTA 4KAYA 3WAXA 3B5QA 3OT9A 2W5TA 1EW9A 3M7VA 4QAXA 5TJ3A 4ZG9A 2W5VA 1KHNA 4UPKA 4CYSA 1KHKA 1ZEFA 4MIVA 4NWXA 5IJQA 3T01A 5DLWA 2GSOA 4CXUA 3NKRA 2D1GA 1ANJA 2XR9A 3DPCA 4FDJA 2ZKTA 5IJSA 1E33P 2RH6A 1Y7AA 1SHQA 1ZEDA 1EJJA 1AJBA 2IFYA 3ED4A 4YR1A 1SHNA 4ZGAA 3MK2A 3MK0A 1KH5A 4KM4A 3IDDA 3BDFA 4GTWA 4NWJA 1HQAA 1E2SP 3WBHA 1URAA 4GTXA 3M8WA 1ELXA 1AUKA 3NKOA 1AJCA 2X98A 4LRBA 3T00A 5EGEA 2GSNA 5L0EA 4LR9A 4CXKA 4UPHA 2W5RA 5L0KA 1N2KA 1ED8A 2G9YA 1HJKA 2W8SA 4UPLA 5LRMA 4CXSA 3CMRA 1URBA 1FSUA
chains in the Genus database with same CATH superfamily
2W5QA 4FDIA 1EW2A 5DLVA 1AJAA 5KXAA 5L0BA 1ALJA 1KHJA 2W5SA 3NKMA 1O98A 2W5WA 5INHA 2IUCA 3BDHA 3E2DA 3A52A 3LXQA 2GLQA 4LREA 5LIAA 1ALKA 4LRFA 4TN0A 1O99A 2IUCB 1KH9A 5EGHA 4MY4A 4B56A 3TWZA 4LR2A 1EW8A 1Y6VA 3NVLA 4ZG7A 4KAVA 4ZG6A 2QZUA 3MK1A 2W5XA 3SZYA 2XRGA 4KJGA 3TX0A 3IGYB 3M8YA 3IGZB 2GSUA 3UNYA 1ALIA 1ZEBA 1KHLA 4LQYA 3NKQA 1K7HA 4UOPA 1EI6A 1EQJA 2W8DA 1HDHA 3KD8A 3Q3QA 4UPIA 3T02A 3NKPA 3UN2A 1ANIA 1AJDA 1B8JA 4LRCA 4CYRA 3WAVA 1ELZA 5DLTA 3WAWA 4LRDA 3M8ZA 1ED9A 4KJDA 4UOOA 4GTYA 4LRAA 2GA3A 4UORA 5K4PA 1ALHA 1KH7A 3SZZA 1E1ZP 1N2LA 3BDGA 5GOVA 1KH4A 3NKNA 2VQRA 1E3CP 4N7TA 4LR7A 1P49A 3DYCA 5AJ9A 4MHXA 2ANHA 3UN5A 5C66A 3WAYA 3BDGB 5LRNA 3UO0A 4GTZA 3UN3A 5GRRA 3TG0A 5LQQA 1ELYA 4LR8A 5HRTA 4KAYA 3WAXA 3B5QA 3OT9A 2W5TA 1EW9A 3M7VA 4QAXA 5TJ3A 4ZG9A 2W5VA 1KHNA 4UPKA 4CYSA 1KHKA 1ZEFA 4MIVA 4NWXA 5IJQA 3T01A 5DLWA 2GSOA 4CXUA 3NKRA 2D1GA 1ANJA 2XR9A 3DPCA 4FDJA 2ZKTA 5IJSA 1E33P 2RH6A 1Y7AA 1SHQA 1ZEDA 1EJJA 1AJBA 2IFYA 3ED4A 4YR1A 1SHNA 4ZGAA 3MK2A 3MK0A 1KH5A 4KM4A 3IDDA 3BDFA 4GTWA 4NWJA 1HQAA 1E2SP 3WBHA 1URAA 4GTXA 3M8WA 1ELXA 1AUKA 3NKOA 1AJCA 2X98A 4LRBA 3T00A 5EGEA 2GSNA 5L0EA 4LR9A 4CXKA 4UPHA 2W5RA 5L0KA 1N2KA 1ED8A 2G9YA 1HJKA 2W8SA 4UPLA 5LRMA 4CXSA 3CMRA 1URBA 1FSUA
chains in the Genus database with same CATH topology
2W5QA 4FDIA 1EW2A 5DLVA 1AJAA 5KXAA 5L0BA 1ALJA 1KHJA 2W5SA 3NKMA 1O98A 2W5WA 5INHA 2IUCA 3BDHA 3E2DA 3A52A 3LXQA 2GLQA 4LREA 5LIAA 1ALKA 4LRFA 4TN0A 1O99A 2IUCB 1KH9A 5EGHA 4MY4A 4B56A 3TWZA 4LR2A 1EW8A 1Y6VA 3NVLA 4ZG7A 4KAVA 4ZG6A 2QZUA 3MK1A 2W5XA 3SZYA 2XRGA 4KJGA 3TX0A 3IGYB 3M8YA 3IGZB 2GSUA 3UNYA 1ALIA 1ZEBA 1KHLA 4LQYA 3NKQA 1K7HA 4UOPA 1EI6A 1EQJA 2W8DA 1HDHA 3KD8A 3Q3QA 4UPIA 3T02A 3NKPA 3UN2A 1ANIA 1AJDA 1B8JA 4LRCA 4CYRA 3WAVA 1ELZA 5DLTA 3WAWA 4LRDA 3M8ZA 1ED9A 4KJDA 4UOOA 4GTYA 4LRAA 2GA3A 4UORA 5K4PA 1ALHA 1KH7A 3SZZA 1E1ZP 1N2LA 3BDGA 5GOVA 1KH4A 3NKNA 2VQRA 1E3CP 4N7TA 4LR7A 1P49A 3DYCA 5AJ9A 4MHXA 2ANHA 3UN5A 5C66A 3WAYA 3BDGB 5LRNA 3UO0A 4GTZA 3UN3A 5GRRA 3TG0A 5LQQA 1ELYA 4LR8A 5HRTA 4KAYA 3WAXA 3B5QA 3OT9A 2W5TA 1EW9A 3M7VA 4QAXA 5TJ3A 4ZG9A 2W5VA 1KHNA 4UPKA 4CYSA 1KHKA 1ZEFA 4MIVA 4NWXA 5IJQA 3T01A 5DLWA 2GSOA 4CXUA 3NKRA 2D1GA 1ANJA 2XR9A 3DPCA 4FDJA 2ZKTA 5IJSA 1E33P 2RH6A 1Y7AA 1SHQA 1ZEDA 1EJJA 1AJBA 2IFYA 3ED4A 4YR1A 1SHNA 4ZGAA 3MK2A 3MK0A 1KH5A 4KM4A 3IDDA 3BDFA 4GTWA 4NWJA 1HQAA 1E2SP 3WBHA 1URAA 4GTXA 3M8WA 1ELXA 1AUKA 3NKOA 1AJCA 2X98A 4LRBA 3T00A 5EGEA 2GSNA 5L0EA 4LR9A 4CXKA 4UPHA 2W5RA 5L0KA 1N2KA 1ED8A 2G9YA 1HJKA 2W8SA 4UPLA 5LRMA 4CXSA 3CMRA 1URBA 1FSUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W5Q A;  4FDI A;  1EW2 A;  5DLV A;  1AJA A;  5KXA A;  5L0B A;  1ALJ A;  1KHJ A;  2W5S A;  3NKM A;  1O98 A;  2W5W A;  5INH A;  2IUC A;  3BDH A;  3E2D A;  3A52 A;  3LXQ A;  2GLQ A;  4LRE A;  5LIA A;  1ALK A;  4LRF A;  4TN0 A;  1O99 A;  2IUC B;  1KH9 A;  5EGH A;  4MY4 A;  4B56 A;  3TWZ A;  4LR2 A;  1EW8 A;  1Y6V A;  3NVL A;  4ZG7 A;  4KAV A;  4ZG6 A;  2QZU A;  3MK1 A;  2W5X A;  3SZY A;  2XRG A;  4KJG A;  3TX0 A;  3IGY B;  3M8Y A;  3IGZ B;  2GSU A;  3UNY A;  1ALI A;  1ZEB A;  1KHL A;  4LQY A;  3NKQ A;  1K7H A;  4UOP A;  1EI6 A;  1EQJ A;  2W8D A;  1HDH A;  3KD8 A;  3Q3Q A;  4UPI A;  3T02 A;  3NKP A;  3UN2 A;  1ANI A;  1AJD A;  1B8J A;  4LRC A;  4CYR A;  3WAV A;  1ELZ A;  5DLT A;  3WAW A;  4LRD A;  3M8Z A;  1ED9 A;  4KJD A;  4UOO A;  4GTY A;  4LRA A;  2GA3 A;  4UOR A;  5K4P A;  1ALH A;  1KH7 A;  3SZZ A;  1E1Z P;  1N2L A;  3BDG A;  5GOV A;  1KH4 A;  3NKN A;  2VQR A;  1E3C P;  4N7T A;  4LR7 A;  1P49 A;  3DYC A;  5AJ9 A;  4MHX A;  2ANH A;  3UN5 A;  5C66 A;  3WAY A;  3BDG B;  5LRN A;  3UO0 A;  4GTZ A;  3UN3 A;  5GRR A;  3TG0 A;  5LQQ A;  1ELY A;  4LR8 A;  5HRT A;  4KAY A;  3WAX A;  3B5Q A;  3OT9 A;  2W5T A;  1EW9 A;  3M7V A;  4QAX A;  5TJ3 A;  4ZG9 A;  2W5V A;  1KHN A;  4UPK A;  4CYS A;  1KHK A;  1ZEF A;  4MIV A;  4NWX A;  5IJQ A;  3T01 A;  5DLW A;  2GSO A;  4CXU A;  3NKR A;  2D1G A;  1ANJ A;  2XR9 A;  3DPC A;  4FDJ A;  2ZKT A;  5IJS A;  1E33 P;  2RH6 A;  1Y7A A;  1SHQ A;  1ZED A;  1EJJ A;  1AJB A;  2IFY A;  3ED4 A;  4YR1 A;  1SHN A;  4ZGA A;  3MK2 A;  3MK0 A;  1KH5 A;  4KM4 A;  3IDD A;  3BDF A;  4GTW A;  4NWJ A;  1HQA A;  1E2S P;  3WBH A;  1URA A;  4GTX A;  3M8W A;  1ELX A;  1AUK A;  3NKO A;  1AJC A;  2X98 A;  4LRB A;  3T00 A;  5EGE A;  2GSN A;  5L0E A;  4LR9 A;  4CXK A;  4UPH A;  2W5R A;  5L0K A;  1N2K A;  1ED8 A;  2G9Y A;  1HJK A;  2W8S A;  4UPL A;  5LRM A;  4CXS A;  3CMR A;  1URB A;  1FSU A; 
#chains in the Genus database with same CATH topology
 2W5Q A;  4FDI A;  1EW2 A;  5DLV A;  1AJA A;  5KXA A;  5L0B A;  1ALJ A;  1KHJ A;  2W5S A;  3NKM A;  1O98 A;  2W5W A;  5INH A;  2IUC A;  3BDH A;  3E2D A;  3A52 A;  3LXQ A;  2GLQ A;  4LRE A;  5LIA A;  1ALK A;  4LRF A;  4TN0 A;  1O99 A;  2IUC B;  1KH9 A;  5EGH A;  4MY4 A;  4B56 A;  3TWZ A;  4LR2 A;  1EW8 A;  1Y6V A;  3NVL A;  4ZG7 A;  4KAV A;  4ZG6 A;  2QZU A;  3MK1 A;  2W5X A;  3SZY A;  2XRG A;  4KJG A;  3TX0 A;  3IGY B;  3M8Y A;  3IGZ B;  2GSU A;  3UNY A;  1ALI A;  1ZEB A;  1KHL A;  4LQY A;  3NKQ A;  1K7H A;  4UOP A;  1EI6 A;  1EQJ A;  2W8D A;  1HDH A;  3KD8 A;  3Q3Q A;  4UPI A;  3T02 A;  3NKP A;  3UN2 A;  1ANI A;  1AJD A;  1B8J A;  4LRC A;  4CYR A;  3WAV A;  1ELZ A;  5DLT A;  3WAW A;  4LRD A;  3M8Z A;  1ED9 A;  4KJD A;  4UOO A;  4GTY A;  4LRA A;  2GA3 A;  4UOR A;  5K4P A;  1ALH A;  1KH7 A;  3SZZ A;  1E1Z P;  1N2L A;  3BDG A;  5GOV A;  1KH4 A;  3NKN A;  2VQR A;  1E3C P;  4N7T A;  4LR7 A;  1P49 A;  3DYC A;  5AJ9 A;  4MHX A;  2ANH A;  3UN5 A;  5C66 A;  3WAY A;  3BDG B;  5LRN A;  3UO0 A;  4GTZ A;  3UN3 A;  5GRR A;  3TG0 A;  5LQQ A;  1ELY A;  4LR8 A;  5HRT A;  4KAY A;  3WAX A;  3B5Q A;  3OT9 A;  2W5T A;  1EW9 A;  3M7V A;  4QAX A;  5TJ3 A;  4ZG9 A;  2W5V A;  1KHN A;  4UPK A;  4CYS A;  1KHK A;  1ZEF A;  4MIV A;  4NWX A;  5IJQ A;  3T01 A;  5DLW A;  2GSO A;  4CXU A;  3NKR A;  2D1G A;  1ANJ A;  2XR9 A;  3DPC A;  4FDJ A;  2ZKT A;  5IJS A;  1E33 P;  2RH6 A;  1Y7A A;  1SHQ A;  1ZED A;  1EJJ A;  1AJB A;  2IFY A;  3ED4 A;  4YR1 A;  1SHN A;  4ZGA A;  3MK2 A;  3MK0 A;  1KH5 A;  4KM4 A;  3IDD A;  3BDF A;  4GTW A;  4NWJ A;  1HQA A;  1E2S P;  3WBH A;  1URA A;  4GTX A;  3M8W A;  1ELX A;  1AUK A;  3NKO A;  1AJC A;  2X98 A;  4LRB A;  3T00 A;  5EGE A;  2GSN A;  5L0E A;  4LR9 A;  4CXK A;  4UPH A;  2W5R A;  5L0K A;  1N2K A;  1ED8 A;  2G9Y A;  1HJK A;  2W8S A;  4UPL A;  5LRM A;  4CXS A;  3CMR A;  1URB A;  1FSU A; 
#chains in the Genus database with same CATH homology
 2W5Q A;  4FDI A;  1EW2 A;  5DLV A;  1AJA A;  5KXA A;  5L0B A;  1ALJ A;  1KHJ A;  2W5S A;  3NKM A;  1O98 A;  2W5W A;  5INH A;  2IUC A;  3BDH A;  3E2D A;  3A52 A;  3LXQ A;  2GLQ A;  4LRE A;  5LIA A;  1ALK A;  4LRF A;  4TN0 A;  1O99 A;  2IUC B;  1KH9 A;  5EGH A;  4MY4 A;  4B56 A;  3TWZ A;  4LR2 A;  1EW8 A;  1Y6V A;  3NVL A;  4ZG7 A;  4KAV A;  4ZG6 A;  2QZU A;  3MK1 A;  2W5X A;  3SZY A;  2XRG A;  4KJG A;  3TX0 A;  3IGY B;  3M8Y A;  3IGZ B;  2GSU A;  3UNY A;  1ALI A;  1ZEB A;  1KHL A;  4LQY A;  3NKQ A;  1K7H A;  4UOP A;  1EI6 A;  1EQJ A;  2W8D A;  1HDH A;  3KD8 A;  3Q3Q A;  4UPI A;  3T02 A;  3NKP A;  3UN2 A;  1ANI A;  1AJD A;  1B8J A;  4LRC A;  4CYR A;  3WAV A;  1ELZ A;  5DLT A;  3WAW A;  4LRD A;  3M8Z A;  1ED9 A;  4KJD A;  4UOO A;  4GTY A;  4LRA A;  2GA3 A;  4UOR A;  5K4P A;  1ALH A;  1KH7 A;  3SZZ A;  1E1Z P;  1N2L A;  3BDG A;  5GOV A;  1KH4 A;  3NKN A;  2VQR A;  1E3C P;  4N7T A;  4LR7 A;  1P49 A;  3DYC A;  5AJ9 A;  4MHX A;  2ANH A;  3UN5 A;  5C66 A;  3WAY A;  3BDG B;  5LRN A;  3UO0 A;  4GTZ A;  3UN3 A;  5GRR A;  3TG0 A;  5LQQ A;  1ELY A;  4LR8 A;  5HRT A;  4KAY A;  3WAX A;  3B5Q A;  3OT9 A;  2W5T A;  1EW9 A;  3M7V A;  4QAX A;  5TJ3 A;  4ZG9 A;  2W5V A;  1KHN A;  4UPK A;  4CYS A;  1KHK A;  1ZEF A;  4MIV A;  4NWX A;  5IJQ A;  3T01 A;  5DLW A;  2GSO A;  4CXU A;  3NKR A;  2D1G A;  1ANJ A;  2XR9 A;  3DPC A;  4FDJ A;  2ZKT A;  5IJS A;  1E33 P;  2RH6 A;  1Y7A A;  1SHQ A;  1ZED A;  1EJJ A;  1AJB A;  2IFY A;  3ED4 A;  4YR1 A;  1SHN A;  4ZGA A;  3MK2 A;  3MK0 A;  1KH5 A;  4KM4 A;  3IDD A;  3BDF A;  4GTW A;  4NWJ A;  1HQA A;  1E2S P;  3WBH A;  1URA A;  4GTX A;  3M8W A;  1ELX A;  1AUK A;  3NKO A;  1AJC A;  2X98 A;  4LRB A;  3T00 A;  5EGE A;  2GSN A;  5L0E A;  4LR9 A;  4CXK A;  4UPH A;  2W5R A;  5L0K A;  1N2K A;  1ED8 A;  2G9Y A;  1HJK A;  2W8S A;  4UPL A;  5LRM A;  4CXS A;  3CMR A;  1URB A;  1FSU A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...