1Y7AA

Structure of d153h/k328w e. coli alkaline phosphatase in presence of cobalt at 1.77 a resolution
Total Genus 162
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
162
Knots found
sequence length
449
structure length
449
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQHATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDWQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Metal Specificity Is Correlated with Two Crucial Active Site Residues in Escherichia coli Alkaline Phosphatase(,).
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 162
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1y7aA00
1URBA 4LREA 1ELXA 1ELZA 3UN5A 5INHA 2XRGA 3CMRA 4TN0A 2IUCB 3UN3A 4GTWA 4NWXA 4LR8A 4KJGA 3LXQA 4LR2A 1KHJA 4LRBA 1AUKA 4CXUA 2XR9A 3MK1A 3SZYA 5C66A 1AJBA 2RH6A 4LR9A 5HRTA 3TG0A 4CXSA 5L0KA 3A52A 4MY4A 2ZKTA 4N7TA 1ALJA 4UPIA 5AJ9A 3WAWA 5LRMA 3M8WA 3WBHA 3WAVA 1ZEDA 1KH7A 3T00A 1E33P 1SHNA 4ZG7A 3WAYA 4GTYA 2GLQA 2GA3A 5DLVA 1KH4A 1KHKA 1AJAA 1E3CP 3DPCA 2QZUA 1N2LA 1P49A 4LRDA 3SZZA 1O99A 2G9YA 3IGZB 4UPLA 3NKMA 1ALKA 1KH9A 1ANJA 1KHNA 1ED9A 3BDGB 5EGHA 4MHXA 5DLWA 4LQYA 2ANHA 1EW8A 3WAXA 4KAVA 4KJDA 3UO0A 4UOPA 5IJSA 1KHLA 2W5WA 3E2DA 1EW2A 3BDHA 1ANIA 2GSNA 2D1GA 2W5TA 3IDDA 2W5RA 4CXKA 3NKOA 1EQJA 2X98A 2W8DA 5EGEA 3OT9A 2W5XA 4GTZA 3NVLA 2IFYA 3NKQA 4QAXA 5DLTA 5L0EA 4LRCA 2W8SA 3IGYB 3KD8A 5LQQA 5TJ3A 1N2KA 3MK0A 3T01A 1SHQA 3MK2A 1ALHA 2GSUA 1EW9A 3NKRA 1K7HA 2W5SA 4ZGAA 4CYRA 2GSOA 1ELYA 4ZG9A 4UORA 3DYCA 3TWZA 4UPKA 4FDIA 1B8JA 5GRRA 1EJJA 3NKPA 5LIAA 4LR7A 5IJQA 5L0BA 1E2SP 3BDGA 4CYSA 2W5VA 1ZEFA 4FDJA 4KM4A 1ZEBA 1KH5A 5K4PA 1FSUA 4YR1A 4UOOA 3UNYA 3UN2A 1Y6VA 2IUCA 1URAA 1HJKA 2VQRA 4KAYA 1Y7AA 1HQAA 3B5QA 5KXAA 1ED8A 1HDHA 4B56A 3M8YA 4GTXA 1EI6A 3BDFA 3M7VA 4LRAA 4UPHA 3TX0A 4ZG6A 1O98A 3ED4A 4LRFA 3M8ZA 1E1ZP 3Q3QA 2W5QA 3T02A 5LRNA 1ALIA 4NWJA 4MIVA 3NKNA 1AJCA 5GOVA 1AJDA
chains in the Genus database with same CATH superfamily
1URBA 4LREA 1ELXA 1ELZA 3UN5A 5INHA 2XRGA 3CMRA 4TN0A 2IUCB 3UN3A 4GTWA 4NWXA 4LR8A 4KJGA 3LXQA 4LR2A 1KHJA 4LRBA 1AUKA 4CXUA 2XR9A 3MK1A 3SZYA 5C66A 1AJBA 2RH6A 4LR9A 5HRTA 3TG0A 4CXSA 5L0KA 3A52A 4MY4A 2ZKTA 4N7TA 1ALJA 4UPIA 5AJ9A 3WAWA 5LRMA 3M8WA 3WBHA 3WAVA 1ZEDA 1KH7A 3T00A 1E33P 1SHNA 4ZG7A 3WAYA 4GTYA 2GLQA 2GA3A 5DLVA 1KH4A 1KHKA 1AJAA 1E3CP 3DPCA 2QZUA 1N2LA 1P49A 4LRDA 3SZZA 1O99A 2G9YA 3IGZB 4UPLA 3NKMA 1ALKA 1KH9A 1ANJA 1KHNA 1ED9A 3BDGB 5EGHA 4MHXA 5DLWA 4LQYA 2ANHA 1EW8A 3WAXA 4KAVA 4KJDA 3UO0A 4UOPA 5IJSA 1KHLA 2W5WA 3E2DA 1EW2A 3BDHA 1ANIA 2GSNA 2D1GA 2W5TA 3IDDA 2W5RA 4CXKA 3NKOA 1EQJA 2X98A 2W8DA 5EGEA 3OT9A 2W5XA 4GTZA 3NVLA 2IFYA 3NKQA 4QAXA 5DLTA 5L0EA 4LRCA 2W8SA 3IGYB 3KD8A 5LQQA 5TJ3A 1N2KA 3MK0A 3T01A 1SHQA 3MK2A 1ALHA 2GSUA 1EW9A 3NKRA 1K7HA 2W5SA 4ZGAA 4CYRA 2GSOA 1ELYA 4ZG9A 4UORA 3DYCA 3TWZA 4UPKA 4FDIA 1B8JA 5GRRA 1EJJA 3NKPA 5LIAA 4LR7A 5IJQA 5L0BA 1E2SP 3BDGA 4CYSA 2W5VA 1ZEFA 4FDJA 4KM4A 1ZEBA 1KH5A 5K4PA 1FSUA 4YR1A 4UOOA 3UNYA 3UN2A 1Y6VA 2IUCA 1URAA 1HJKA 2VQRA 4KAYA 1Y7AA 1HQAA 3B5QA 5KXAA 1ED8A 1HDHA 4B56A 3M8YA 4GTXA 1EI6A 3BDFA 3M7VA 4LRAA 4UPHA 3TX0A 4ZG6A 1O98A 3ED4A 4LRFA 3M8ZA 1E1ZP 3Q3QA 2W5QA 3T02A 5LRNA 1ALIA 4NWJA 4MIVA 3NKNA 1AJCA 5GOVA 1AJDA
chains in the Genus database with same CATH topology
1URBA 4LREA 1ELXA 1ELZA 3UN5A 5INHA 2XRGA 3CMRA 4TN0A 2IUCB 3UN3A 4GTWA 4NWXA 4LR8A 4KJGA 3LXQA 4LR2A 1KHJA 4LRBA 1AUKA 4CXUA 2XR9A 3MK1A 3SZYA 5C66A 1AJBA 2RH6A 4LR9A 5HRTA 3TG0A 4CXSA 5L0KA 3A52A 4MY4A 2ZKTA 4N7TA 1ALJA 4UPIA 5AJ9A 3WAWA 5LRMA 3M8WA 3WBHA 3WAVA 1ZEDA 1KH7A 3T00A 1E33P 1SHNA 4ZG7A 3WAYA 4GTYA 2GLQA 2GA3A 5DLVA 1KH4A 1KHKA 1AJAA 1E3CP 3DPCA 2QZUA 1N2LA 1P49A 4LRDA 3SZZA 1O99A 2G9YA 3IGZB 4UPLA 3NKMA 1ALKA 1KH9A 1ANJA 1KHNA 1ED9A 3BDGB 5EGHA 4MHXA 5DLWA 4LQYA 2ANHA 1EW8A 3WAXA 4KAVA 4KJDA 3UO0A 4UOPA 5IJSA 1KHLA 2W5WA 3E2DA 1EW2A 3BDHA 1ANIA 2GSNA 2D1GA 2W5TA 3IDDA 2W5RA 4CXKA 3NKOA 1EQJA 2X98A 2W8DA 5EGEA 3OT9A 2W5XA 4GTZA 3NVLA 2IFYA 3NKQA 4QAXA 5DLTA 5L0EA 4LRCA 2W8SA 3IGYB 3KD8A 5LQQA 5TJ3A 1N2KA 3MK0A 3T01A 1SHQA 3MK2A 1ALHA 2GSUA 1EW9A 3NKRA 1K7HA 2W5SA 4ZGAA 4CYRA 2GSOA 1ELYA 4ZG9A 4UORA 3DYCA 3TWZA 4UPKA 4FDIA 1B8JA 5GRRA 1EJJA 3NKPA 5LIAA 4LR7A 5IJQA 5L0BA 1E2SP 3BDGA 4CYSA 2W5VA 1ZEFA 4FDJA 4KM4A 1ZEBA 1KH5A 5K4PA 1FSUA 4YR1A 4UOOA 3UNYA 3UN2A 1Y6VA 2IUCA 1URAA 1HJKA 2VQRA 4KAYA 1Y7AA 1HQAA 3B5QA 5KXAA 1ED8A 1HDHA 4B56A 3M8YA 4GTXA 1EI6A 3BDFA 3M7VA 4LRAA 4UPHA 3TX0A 4ZG6A 1O98A 3ED4A 4LRFA 3M8ZA 1E1ZP 3Q3QA 2W5QA 3T02A 5LRNA 1ALIA 4NWJA 4MIVA 3NKNA 1AJCA 5GOVA 1AJDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1URB A;  4LRE A;  1ELX A;  1ELZ A;  3UN5 A;  5INH A;  2XRG A;  3CMR A;  4TN0 A;  2IUC B;  3UN3 A;  4GTW A;  4NWX A;  4LR8 A;  4KJG A;  3LXQ A;  4LR2 A;  1KHJ A;  4LRB A;  1AUK A;  4CXU A;  2XR9 A;  3MK1 A;  3SZY A;  5C66 A;  1AJB A;  2RH6 A;  4LR9 A;  5HRT A;  3TG0 A;  4CXS A;  5L0K A;  3A52 A;  4MY4 A;  2ZKT A;  4N7T A;  1ALJ A;  4UPI A;  5AJ9 A;  3WAW A;  5LRM A;  3M8W A;  3WBH A;  3WAV A;  1ZED A;  1KH7 A;  3T00 A;  1E33 P;  1SHN A;  4ZG7 A;  3WAY A;  4GTY A;  2GLQ A;  2GA3 A;  5DLV A;  1KH4 A;  1KHK A;  1AJA A;  1E3C P;  3DPC A;  2QZU A;  1N2L A;  1P49 A;  4LRD A;  3SZZ A;  1O99 A;  2G9Y A;  3IGZ B;  4UPL A;  3NKM A;  1ALK A;  1KH9 A;  1ANJ A;  1KHN A;  1ED9 A;  3BDG B;  5EGH A;  4MHX A;  5DLW A;  4LQY A;  2ANH A;  1EW8 A;  3WAX A;  4KAV A;  4KJD A;  3UO0 A;  4UOP A;  5IJS A;  1KHL A;  2W5W A;  3E2D A;  1EW2 A;  3BDH A;  1ANI A;  2GSN A;  2D1G A;  2W5T A;  3IDD A;  2W5R A;  4CXK A;  3NKO A;  1EQJ A;  2X98 A;  2W8D A;  5EGE A;  3OT9 A;  2W5X A;  4GTZ A;  3NVL A;  2IFY A;  3NKQ A;  4QAX A;  5DLT A;  5L0E A;  4LRC A;  2W8S A;  3IGY B;  3KD8 A;  5LQQ A;  5TJ3 A;  1N2K A;  3MK0 A;  3T01 A;  1SHQ A;  3MK2 A;  1ALH A;  2GSU A;  1EW9 A;  3NKR A;  1K7H A;  2W5S A;  4ZGA A;  4CYR A;  2GSO A;  1ELY A;  4ZG9 A;  4UOR A;  3DYC A;  3TWZ A;  4UPK A;  4FDI A;  1B8J A;  5GRR A;  1EJJ A;  3NKP A;  5LIA A;  4LR7 A;  5IJQ A;  5L0B A;  1E2S P;  3BDG A;  4CYS A;  2W5V A;  1ZEF A;  4FDJ A;  4KM4 A;  1ZEB A;  1KH5 A;  5K4P A;  1FSU A;  4YR1 A;  4UOO A;  3UNY A;  3UN2 A;  1Y6V A;  2IUC A;  1URA A;  1HJK A;  2VQR A;  4KAY A;  1Y7A A;  1HQA A;  3B5Q A;  5KXA A;  1ED8 A;  1HDH A;  4B56 A;  3M8Y A;  4GTX A;  1EI6 A;  3BDF A;  3M7V A;  4LRA A;  4UPH A;  3TX0 A;  4ZG6 A;  1O98 A;  3ED4 A;  4LRF A;  3M8Z A;  1E1Z P;  3Q3Q A;  2W5Q A;  3T02 A;  5LRN A;  1ALI A;  4NWJ A;  4MIV A;  3NKN A;  1AJC A;  5GOV A;  1AJD A; 
#chains in the Genus database with same CATH topology
 1URB A;  4LRE A;  1ELX A;  1ELZ A;  3UN5 A;  5INH A;  2XRG A;  3CMR A;  4TN0 A;  2IUC B;  3UN3 A;  4GTW A;  4NWX A;  4LR8 A;  4KJG A;  3LXQ A;  4LR2 A;  1KHJ A;  4LRB A;  1AUK A;  4CXU A;  2XR9 A;  3MK1 A;  3SZY A;  5C66 A;  1AJB A;  2RH6 A;  4LR9 A;  5HRT A;  3TG0 A;  4CXS A;  5L0K A;  3A52 A;  4MY4 A;  2ZKT A;  4N7T A;  1ALJ A;  4UPI A;  5AJ9 A;  3WAW A;  5LRM A;  3M8W A;  3WBH A;  3WAV A;  1ZED A;  1KH7 A;  3T00 A;  1E33 P;  1SHN A;  4ZG7 A;  3WAY A;  4GTY A;  2GLQ A;  2GA3 A;  5DLV A;  1KH4 A;  1KHK A;  1AJA A;  1E3C P;  3DPC A;  2QZU A;  1N2L A;  1P49 A;  4LRD A;  3SZZ A;  1O99 A;  2G9Y A;  3IGZ B;  4UPL A;  3NKM A;  1ALK A;  1KH9 A;  1ANJ A;  1KHN A;  1ED9 A;  3BDG B;  5EGH A;  4MHX A;  5DLW A;  4LQY A;  2ANH A;  1EW8 A;  3WAX A;  4KAV A;  4KJD A;  3UO0 A;  4UOP A;  5IJS A;  1KHL A;  2W5W A;  3E2D A;  1EW2 A;  3BDH A;  1ANI A;  2GSN A;  2D1G A;  2W5T A;  3IDD A;  2W5R A;  4CXK A;  3NKO A;  1EQJ A;  2X98 A;  2W8D A;  5EGE A;  3OT9 A;  2W5X A;  4GTZ A;  3NVL A;  2IFY A;  3NKQ A;  4QAX A;  5DLT A;  5L0E A;  4LRC A;  2W8S A;  3IGY B;  3KD8 A;  5LQQ A;  5TJ3 A;  1N2K A;  3MK0 A;  3T01 A;  1SHQ A;  3MK2 A;  1ALH A;  2GSU A;  1EW9 A;  3NKR A;  1K7H A;  2W5S A;  4ZGA A;  4CYR A;  2GSO A;  1ELY A;  4ZG9 A;  4UOR A;  3DYC A;  3TWZ A;  4UPK A;  4FDI A;  1B8J A;  5GRR A;  1EJJ A;  3NKP A;  5LIA A;  4LR7 A;  5IJQ A;  5L0B A;  1E2S P;  3BDG A;  4CYS A;  2W5V A;  1ZEF A;  4FDJ A;  4KM4 A;  1ZEB A;  1KH5 A;  5K4P A;  1FSU A;  4YR1 A;  4UOO A;  3UNY A;  3UN2 A;  1Y6V A;  2IUC A;  1URA A;  1HJK A;  2VQR A;  4KAY A;  1Y7A A;  1HQA A;  3B5Q A;  5KXA A;  1ED8 A;  1HDH A;  4B56 A;  3M8Y A;  4GTX A;  1EI6 A;  3BDF A;  3M7V A;  4LRA A;  4UPH A;  3TX0 A;  4ZG6 A;  1O98 A;  3ED4 A;  4LRF A;  3M8Z A;  1E1Z P;  3Q3Q A;  2W5Q A;  3T02 A;  5LRN A;  1ALI A;  4NWJ A;  4MIV A;  3NKN A;  1AJC A;  5GOV A;  1AJD A; 
#chains in the Genus database with same CATH homology
 1URB A;  4LRE A;  1ELX A;  1ELZ A;  3UN5 A;  5INH A;  2XRG A;  3CMR A;  4TN0 A;  2IUC B;  3UN3 A;  4GTW A;  4NWX A;  4LR8 A;  4KJG A;  3LXQ A;  4LR2 A;  1KHJ A;  4LRB A;  1AUK A;  4CXU A;  2XR9 A;  3MK1 A;  3SZY A;  5C66 A;  1AJB A;  2RH6 A;  4LR9 A;  5HRT A;  3TG0 A;  4CXS A;  5L0K A;  3A52 A;  4MY4 A;  2ZKT A;  4N7T A;  1ALJ A;  4UPI A;  5AJ9 A;  3WAW A;  5LRM A;  3M8W A;  3WBH A;  3WAV A;  1ZED A;  1KH7 A;  3T00 A;  1E33 P;  1SHN A;  4ZG7 A;  3WAY A;  4GTY A;  2GLQ A;  2GA3 A;  5DLV A;  1KH4 A;  1KHK A;  1AJA A;  1E3C P;  3DPC A;  2QZU A;  1N2L A;  1P49 A;  4LRD A;  3SZZ A;  1O99 A;  2G9Y A;  3IGZ B;  4UPL A;  3NKM A;  1ALK A;  1KH9 A;  1ANJ A;  1KHN A;  1ED9 A;  3BDG B;  5EGH A;  4MHX A;  5DLW A;  4LQY A;  2ANH A;  1EW8 A;  3WAX A;  4KAV A;  4KJD A;  3UO0 A;  4UOP A;  5IJS A;  1KHL A;  2W5W A;  3E2D A;  1EW2 A;  3BDH A;  1ANI A;  2GSN A;  2D1G A;  2W5T A;  3IDD A;  2W5R A;  4CXK A;  3NKO A;  1EQJ A;  2X98 A;  2W8D A;  5EGE A;  3OT9 A;  2W5X A;  4GTZ A;  3NVL A;  2IFY A;  3NKQ A;  4QAX A;  5DLT A;  5L0E A;  4LRC A;  2W8S A;  3IGY B;  3KD8 A;  5LQQ A;  5TJ3 A;  1N2K A;  3MK0 A;  3T01 A;  1SHQ A;  3MK2 A;  1ALH A;  2GSU A;  1EW9 A;  3NKR A;  1K7H A;  2W5S A;  4ZGA A;  4CYR A;  2GSO A;  1ELY A;  4ZG9 A;  4UOR A;  3DYC A;  3TWZ A;  4UPK A;  4FDI A;  1B8J A;  5GRR A;  1EJJ A;  3NKP A;  5LIA A;  4LR7 A;  5IJQ A;  5L0B A;  1E2S P;  3BDG A;  4CYS A;  2W5V A;  1ZEF A;  4FDJ A;  4KM4 A;  1ZEB A;  1KH5 A;  5K4P A;  1FSU A;  4YR1 A;  4UOO A;  3UNY A;  3UN2 A;  1Y6V A;  2IUC A;  1URA A;  1HJK A;  2VQR A;  4KAY A;  1Y7A A;  1HQA A;  3B5Q A;  5KXA A;  1ED8 A;  1HDH A;  4B56 A;  3M8Y A;  4GTX A;  1EI6 A;  3BDF A;  3M7V A;  4LRA A;  4UPH A;  3TX0 A;  4ZG6 A;  1O98 A;  3ED4 A;  4LRF A;  3M8Z A;  1E1Z P;  3Q3Q A;  2W5Q A;  3T02 A;  5LRN A;  1ALI A;  4NWJ A;  4MIV A;  3NKN A;  1AJC A;  5GOV A;  1AJD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...