1ZEB | Genus

Total Genus 173

Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	173
Knots found	KnotProt 2.0: S +3₁
sequence length	480
structure length	479
Chain Sequence	IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPA

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__529376224072221__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__529376224072221__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/1zeb/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__529376224072221__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"529376224072221","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/1zeb/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__529376224072221__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands. pubmed doi rcsb
molecule keywords	Alkaline phosphatase
molecule tags	Hydrolase
total genus	173
structure length	479
sequence length	480
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	2005-04-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1zebA00

4LR9A 1ZEFA 4ZG9A 3M8ZA 4B56A 2RH6A 4CYSA 5L0BA 1KHKA 1ELZA 2GLQA 4KJDA 4KJGA 4TN0A 3UO0A 3NKQA 1E3CP 1N2LA 1EQJA 1AJCA 1URAA 4CXUA 2GSUA 3DPCA 3SZYA 3TG0A 1B8JA 2W8SA 3M8YA 4ZG6A 4CXSA 1EW2A 1ANJA 3MK1A 4LRDA 3BDFA 3TX0A 2IUCA 4FDIA 2ZKTA 4UORA 3TWZA 1ANIA 3MK2A 4QAXA 2W5TA 4NWJA 3UNYA 4UPLA 1AUKA 2W5WA 3T00A 4UPKA 3WAVA 1ZEBA 1ZEDA 2X98A 4UOPA 3MK0A 3Q3QA 3T02A 4GTWA 4UOOA 5HRTA 1E2SP 5KXAA 4FDJA 4KM4A 4GTZA 4LR7A 1HQAA 5LRNA 3B5QA 3UN3A 3BDGB 2VQRA 1KH7A 5DLVA 5IJSA 1ALHA 3WAXA 1ELXA 5EGHA 1P49A 3CMRA 5C66A 4UPHA 1KHLA 4GTXA 2GA3A 1Y7AA 4ZG7A 2W5VA 5L0EA 3IGZB 4GTYA 4LREA 1EW8A 1EJJA 3NKMA 3UN5A 1FSUA 1HDHA 4UPIA 1ELYA 3SZZA 1AJDA 1KHJA 2D1GA 5AJ9A 5INHA 3NKNA 4LR2A 4LRAA 2W5RA 3WBHA 1O99A 1KH4A 1SHNA 2W5QA 4LQYA 3LXQA 3UN2A 2XRGA 5LRMA 1EI6A 5DLTA 3T01A 5K4PA 1ED8A 3NVLA 4N7TA 1HJKA 2GSNA 2W8DA 2XR9A 3ED4A 4NWXA 4YR1A 4CYRA 1K7HA 1KH5A 2ANHA 1ALJA 3OT9A 4MY4A 3IGYB 2G9YA 4KAVA 4LRBA 3WAWA 1O98A 3KD8A 4LRCA 1ED9A 1E33P 5IJQA 2IFYA 3DYCA 2IUCB 3NKRA 1ALIA 2GSOA 4KAYA 3WAYA 5LIAA 5GOVA 2W5XA 2W5SA 4LRFA 5GRRA 1KH9A 1URBA 3M7VA 1EW9A 3A52A 3BDGA 4LR8A 1KHNA 5EGEA 4MIVA 4ZGAA 1AJBA 3NKPA 4MHXA 3M8WA 3E2DA 1E1ZP 1Y6VA 5L0KA 2QZUA 5DLWA 1ALKA 4CXKA 3BDHA 5LQQA 1SHQA 3IDDA 1N2KA 1AJAA 5TJ3A 3NKOA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4LR9 A;  1ZEF A;  4ZG9 A;  3M8Z A;  4B56 A;  2RH6 A;  4CYS A;  5L0B A;  1KHK A;  1ELZ A;  2GLQ A;  4KJD A;  4KJG A;  4TN0 A;  3UO0 A;  3NKQ A;  1E3C P;  1N2L A;  1EQJ A;  1AJC A;  1URA A;  4CXU A;  2GSU A;  3DPC A;  3SZY A;  3TG0 A;  1B8J A;  2W8S A;  3M8Y A;  4ZG6 A;  4CXS A;  1EW2 A;  1ANJ A;  3MK1 A;  4LRD A;  3BDF A;  3TX0 A;  2IUC A;  4FDI A;  2ZKT A;  4UOR A;  3TWZ A;  1ANI A;  3MK2 A;  4QAX A;  2W5T A;  4NWJ A;  3UNY A;  4UPL A;  1AUK A;  2W5W A;  3T00 A;  4UPK A;  3WAV A;  1ZEB A;  1ZED A;  2X98 A;  4UOP A;  3MK0 A;  3Q3Q A;  3T02 A;  4GTW A;  4UOO A;  5HRT A;  1E2S P;  5KXA A;  4FDJ A;  4KM4 A;  4GTZ A;  4LR7 A;  1HQA A;  5LRN A;  3B5Q A;  3UN3 A;  3BDG B;  2VQR A;  1KH7 A;  5DLV A;  5IJS A;  1ALH A;  3WAX A;  1ELX A;  5EGH A;  1P49 A;  3CMR A;  5C66 A;  4UPH A;  1KHL A;  4GTX A;  2GA3 A;  1Y7A A;  4ZG7 A;  2W5V A;  5L0E A;  3IGZ B;  4GTY A;  4LRE A;  1EW8 A;  1EJJ A;  3NKM A;  3UN5 A;  1FSU A;  1HDH A;  4UPI A;  1ELY A;  3SZZ A;  1AJD A;  1KHJ A;  2D1G A;  5AJ9 A;  5INH A;  3NKN A;  4LR2 A;  4LRA A;  2W5R A;  3WBH A;  1O99 A;  1KH4 A;  1SHN A;  2W5Q A;  4LQY A;  3LXQ A;  3UN2 A;  2XRG A;  5LRM A;  1EI6 A;  5DLT A;  3T01 A;  5K4P A;  1ED8 A;  3NVL A;  4N7T A;  1HJK A;  2GSN A;  2W8D A;  2XR9 A;  3ED4 A;  4NWX A;  4YR1 A;  4CYR A;  1K7H A;  1KH5 A;  2ANH A;  1ALJ A;  3OT9 A;  4MY4 A;  3IGY B;  2G9Y A;  4KAV A;  4LRB A;  3WAW A;  1O98 A;  3KD8 A;  4LRC A;  1ED9 A;  1E33 P;  5IJQ A;  2IFY A;  3DYC A;  2IUC B;  3NKR A;  1ALI A;  2GSO A;  4KAY A;  3WAY A;  5LIA A;  5GOV A;  2W5X A;  2W5S A;  4LRF A;  5GRR A;  1KH9 A;  1URB A;  3M7V A;  1EW9 A;  3A52 A;  3BDG A;  4LR8 A;  1KHN A;  5EGE A;  4MIV A;  4ZGA A;  1AJB A;  3NKP A;  4MHX A;  3M8W A;  3E2D A;  1E1Z P;  1Y6V A;  5L0K A;  2QZU A;  5DLW A;  1ALK A;  4CXK A;  3BDH A;  5LQQ A;  1SHQ A;  3IDD A;  1N2K A;  1AJA A;  5TJ3 A;  3NKO A; 
#chains in the Genus database with same CATH topology
 4LR9 A;  1ZEF A;  4ZG9 A;  3M8Z A;  4B56 A;  2RH6 A;  4CYS A;  5L0B A;  1KHK A;  1ELZ A;  2GLQ A;  4KJD A;  4KJG A;  4TN0 A;  3UO0 A;  3NKQ A;  1E3C P;  1N2L A;  1EQJ A;  1AJC A;  1URA A;  4CXU A;  2GSU A;  3DPC A;  3SZY A;  3TG0 A;  1B8J A;  2W8S A;  3M8Y A;  4ZG6 A;  4CXS A;  1EW2 A;  1ANJ A;  3MK1 A;  4LRD A;  3BDF A;  3TX0 A;  2IUC A;  4FDI A;  2ZKT A;  4UOR A;  3TWZ A;  1ANI A;  3MK2 A;  4QAX A;  2W5T A;  4NWJ A;  3UNY A;  4UPL A;  1AUK A;  2W5W A;  3T00 A;  4UPK A;  3WAV A;  1ZEB A;  1ZED A;  2X98 A;  4UOP A;  3MK0 A;  3Q3Q A;  3T02 A;  4GTW A;  4UOO A;  5HRT A;  1E2S P;  5KXA A;  4FDJ A;  4KM4 A;  4GTZ A;  4LR7 A;  1HQA A;  5LRN A;  3B5Q A;  3UN3 A;  3BDG B;  2VQR A;  1KH7 A;  5DLV A;  5IJS A;  1ALH A;  3WAX A;  1ELX A;  5EGH A;  1P49 A;  3CMR A;  5C66 A;  4UPH A;  1KHL A;  4GTX A;  2GA3 A;  1Y7A A;  4ZG7 A;  2W5V A;  5L0E A;  3IGZ B;  4GTY A;  4LRE A;  1EW8 A;  1EJJ A;  3NKM A;  3UN5 A;  1FSU A;  1HDH A;  4UPI A;  1ELY A;  3SZZ A;  1AJD A;  1KHJ A;  2D1G A;  5AJ9 A;  5INH A;  3NKN A;  4LR2 A;  4LRA A;  2W5R A;  3WBH A;  1O99 A;  1KH4 A;  1SHN A;  2W5Q A;  4LQY A;  3LXQ A;  3UN2 A;  2XRG A;  5LRM A;  1EI6 A;  5DLT A;  3T01 A;  5K4P A;  1ED8 A;  3NVL A;  4N7T A;  1HJK A;  2GSN A;  2W8D A;  2XR9 A;  3ED4 A;  4NWX A;  4YR1 A;  4CYR A;  1K7H A;  1KH5 A;  2ANH A;  1ALJ A;  3OT9 A;  4MY4 A;  3IGY B;  2G9Y A;  4KAV A;  4LRB A;  3WAW A;  1O98 A;  3KD8 A;  4LRC A;  1ED9 A;  1E33 P;  5IJQ A;  2IFY A;  3DYC A;  2IUC B;  3NKR A;  1ALI A;  2GSO A;  4KAY A;  3WAY A;  5LIA A;  5GOV A;  2W5X A;  2W5S A;  4LRF A;  5GRR A;  1KH9 A;  1URB A;  3M7V A;  1EW9 A;  3A52 A;  3BDG A;  4LR8 A;  1KHN A;  5EGE A;  4MIV A;  4ZGA A;  1AJB A;  3NKP A;  4MHX A;  3M8W A;  3E2D A;  1E1Z P;  1Y6V A;  5L0K A;  2QZU A;  5DLW A;  1ALK A;  4CXK A;  3BDH A;  5LQQ A;  1SHQ A;  3IDD A;  1N2K A;  1AJA A;  5TJ3 A;  3NKO A; 
#chains in the Genus database with same CATH homology
 4LR9 A;  1ZEF A;  4ZG9 A;  3M8Z A;  4B56 A;  2RH6 A;  4CYS A;  5L0B A;  1KHK A;  1ELZ A;  2GLQ A;  4KJD A;  4KJG A;  4TN0 A;  3UO0 A;  3NKQ A;  1E3C P;  1N2L A;  1EQJ A;  1AJC A;  1URA A;  4CXU A;  2GSU A;  3DPC A;  3SZY A;  3TG0 A;  1B8J A;  2W8S A;  3M8Y A;  4ZG6 A;  4CXS A;  1EW2 A;  1ANJ A;  3MK1 A;  4LRD A;  3BDF A;  3TX0 A;  2IUC A;  4FDI A;  2ZKT A;  4UOR A;  3TWZ A;  1ANI A;  3MK2 A;  4QAX A;  2W5T A;  4NWJ A;  3UNY A;  4UPL A;  1AUK A;  2W5W A;  3T00 A;  4UPK A;  3WAV A;  1ZEB A;  1ZED A;  2X98 A;  4UOP A;  3MK0 A;  3Q3Q A;  3T02 A;  4GTW A;  4UOO A;  5HRT A;  1E2S P;  5KXA A;  4FDJ A;  4KM4 A;  4GTZ A;  4LR7 A;  1HQA A;  5LRN A;  3B5Q A;  3UN3 A;  3BDG B;  2VQR A;  1KH7 A;  5DLV A;  5IJS A;  1ALH A;  3WAX A;  1ELX A;  5EGH A;  1P49 A;  3CMR A;  5C66 A;  4UPH A;  1KHL A;  4GTX A;  2GA3 A;  1Y7A A;  4ZG7 A;  2W5V A;  5L0E A;  3IGZ B;  4GTY A;  4LRE A;  1EW8 A;  1EJJ A;  3NKM A;  3UN5 A;  1FSU A;  1HDH A;  4UPI A;  1ELY A;  3SZZ A;  1AJD A;  1KHJ A;  2D1G A;  5AJ9 A;  5INH A;  3NKN A;  4LR2 A;  4LRA A;  2W5R A;  3WBH A;  1O99 A;  1KH4 A;  1SHN A;  2W5Q A;  4LQY A;  3LXQ A;  3UN2 A;  2XRG A;  5LRM A;  1EI6 A;  5DLT A;  3T01 A;  5K4P A;  1ED8 A;  3NVL A;  4N7T A;  1HJK A;  2GSN A;  2W8D A;  2XR9 A;  3ED4 A;  4NWX A;  4YR1 A;  4CYR A;  1K7H A;  1KH5 A;  2ANH A;  1ALJ A;  3OT9 A;  4MY4 A;  3IGY B;  2G9Y A;  4KAV A;  4LRB A;  3WAW A;  1O98 A;  3KD8 A;  4LRC A;  1ED9 A;  1E33 P;  5IJQ A;  2IFY A;  3DYC A;  2IUC B;  3NKR A;  1ALI A;  2GSO A;  4KAY A;  3WAY A;  5LIA A;  5GOV A;  2W5X A;  2W5S A;  4LRF A;  5GRR A;  1KH9 A;  1URB A;  3M7V A;  1EW9 A;  3A52 A;  3BDG A;  4LR8 A;  1KHN A;  5EGE A;  4MIV A;  4ZGA A;  1AJB A;  3NKP A;  4MHX A;  3M8W A;  3E2D A;  1E1Z P;  1Y6V A;  5L0K A;  2QZU A;  5DLW A;  1ALK A;  4CXK A;  3BDH A;  5LQQ A;  1SHQ A;  3IDD A;  1N2K A;  1AJA A;  5TJ3 A;  3NKO A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

1ZEBA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations