2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
molecule tags Hydrolase
source organism Francisella tularensis subsp. novicida
molecule keywords acid phosphatase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
2ANHA 2W8DA 1ED8A 3M8ZA 1AJBA 4LRDA 4CXKA 3WBHA 1EW8A 4NWJA 4UPIA 2G9YA 2RH6A 3SZZA 3UNYA 3TX0A 5GRRA 3NKMA 2GLQA 4KAVA 4KM4A 1KH5A 3T00A 1KHJA 4ZG9A 3MK2A 4NWXA 5K4PA 4LRAA 1URAA 2IUCB 3UO0A 4LR8A 4MIVA 1AJAA 3NKPA 4LRBA 4B56A 5IJQA 4LQYA 2W5XA 1ALJA 1ANJA 1EW9A 2W5TA 3M7VA 3NKQA 4LREA 1HQAA 5L0KA 1AUKA 4MHXA 1KHNA 2W8SA 1ED9A 1ZEBA 2IFYA 2D1GA 4QAXA 2XRGA 4ZG6A 4LRFA 1N2KA 1O98A 5IJSA 4KJDA 3WAWA 3KD8A 4KJGA 3WAXA 5L0EA 5L0BA 5HRTA 2GSUA 5EGHA 5DLTA 3UN3A 4LRCA 3A52A 1KH7A 3CMRA 3IGZB 3OT9A 2VQRA 1ZEFA 3MK0A 3M8YA 1EJJA 2QZUA 3IGYB 3IDDA 4LR9A 3BDGA 3E2DA 1ALKA 1SHNA 1EQJA 2XR9A 2GSNA 1E2SP 4MY4A 2W5QA 3T01A 1K7HA 1ALHA 5C66A 3LXQA 2W5RA 3MK1A 1FSUA 4ZGAA 4UOOA 1P49A 1E33P 1KHKA 3DPCA 2IUCA 2GSOA 5EGEA 2W5SA 4GTYA 4KAYA 1Y7AA 3TWZA 3UN5A 4UOPA 1AJDA 3BDHA 3Q3QA 3TG0A 4YR1A 1Y6VA 5DLWA 4GTXA 1EI6A 5GOVA 1AJCA 5LRNA 4CYSA 3B5QA 3SZYA 3NKNA 5DLVA 3ED4A 4FDIA 3NVLA 4GTZA 4LR2A 5LRMA 1ALIA 2ZKTA 3M8WA 5LIAA 1HJKA 4CXUA 3UN2A 5AJ9A 4CYRA 2X98A 1KHLA 3BDGB 3NKOA 1ELZA 5KXAA 1O99A 2W5WA 1E1ZP 3T02A 2W5VA 1KH4A 1N2LA 1B8JA 1ANIA 4UPKA 1ZEDA 3WAYA 4ZG7A 1E3CP 1KH9A 1SHQA 3WAVA 4FDJA 5LQQA 4LR7A 4UPLA 4UPHA 3NKRA 4GTWA 1URBA 5TJ3A 4TN0A 4CXSA 2GA3A 3BDFA 3DYCA 1ELYA 4UORA 5INHA 1EW2A 4N7TA 1HDHA 1ELXA
chains in the Genus database with same CATH superfamily
2ANHA 2W8DA 1ED8A 3M8ZA 1AJBA 4LRDA 4CXKA 3WBHA 1EW8A 4NWJA 4UPIA 2G9YA 2RH6A 3SZZA 3UNYA 3TX0A 5GRRA 3NKMA 2GLQA 4KAVA 4KM4A 1KH5A 3T00A 1KHJA 4ZG9A 3MK2A 4NWXA 5K4PA 4LRAA 1URAA 2IUCB 3UO0A 4LR8A 4MIVA 1AJAA 3NKPA 4LRBA 4B56A 5IJQA 4LQYA 2W5XA 1ALJA 1ANJA 1EW9A 2W5TA 3M7VA 3NKQA 4LREA 1HQAA 5L0KA 1AUKA 4MHXA 1KHNA 2W8SA 1ED9A 1ZEBA 2IFYA 2D1GA 4QAXA 2XRGA 4ZG6A 4LRFA 1N2KA 1O98A 5IJSA 4KJDA 3WAWA 3KD8A 4KJGA 3WAXA 5L0EA 5L0BA 5HRTA 2GSUA 5EGHA 5DLTA 3UN3A 4LRCA 3A52A 1KH7A 3CMRA 3IGZB 3OT9A 2VQRA 1ZEFA 3MK0A 3M8YA 1EJJA 2QZUA 3IGYB 3IDDA 4LR9A 3BDGA 3E2DA 1ALKA 1SHNA 1EQJA 2XR9A 2GSNA 1E2SP 4MY4A 2W5QA 3T01A 1K7HA 1ALHA 5C66A 3LXQA 2W5RA 3MK1A 1FSUA 4ZGAA 4UOOA 1P49A 1E33P 1KHKA 3DPCA 2IUCA 2GSOA 5EGEA 2W5SA 4GTYA 4KAYA 1Y7AA 3TWZA 3UN5A 4UOPA 1AJDA 3BDHA 3Q3QA 3TG0A 4YR1A 1Y6VA 5DLWA 4GTXA 1EI6A 5GOVA 1AJCA 5LRNA 4CYSA 3B5QA 3SZYA 3NKNA 5DLVA 3ED4A 4FDIA 3NVLA 4GTZA 4LR2A 5LRMA 1ALIA 2ZKTA 3M8WA 5LIAA 1HJKA 4CXUA 3UN2A 5AJ9A 4CYRA 2X98A 1KHLA 3BDGB 3NKOA 1ELZA 5KXAA 1O99A 2W5WA 1E1ZP 3T02A 2W5VA 1KH4A 1N2LA 1B8JA 1ANIA 4UPKA 1ZEDA 3WAYA 4ZG7A 1E3CP 1KH9A 1SHQA 3WAVA 4FDJA 5LQQA 4LR7A 4UPLA 4UPHA 3NKRA 4GTWA 1URBA 5TJ3A 4TN0A 4CXSA 2GA3A 3BDFA 3DYCA 1ELYA 4UORA 5INHA 1EW2A 4N7TA 1HDHA 1ELXA
chains in the Genus database with same CATH topology
2ANHA 2W8DA 1ED8A 3M8ZA 1AJBA 4LRDA 4CXKA 3WBHA 1EW8A 4NWJA 4UPIA 2G9YA 2RH6A 3SZZA 3UNYA 3TX0A 5GRRA 3NKMA 2GLQA 4KAVA 4KM4A 1KH5A 3T00A 1KHJA 4ZG9A 3MK2A 4NWXA 5K4PA 4LRAA 1URAA 2IUCB 3UO0A 4LR8A 4MIVA 1AJAA 3NKPA 4LRBA 4B56A 5IJQA 4LQYA 2W5XA 1ALJA 1ANJA 1EW9A 2W5TA 3M7VA 3NKQA 4LREA 1HQAA 5L0KA 1AUKA 4MHXA 1KHNA 2W8SA 1ED9A 1ZEBA 2IFYA 2D1GA 4QAXA 2XRGA 4ZG6A 4LRFA 1N2KA 1O98A 5IJSA 4KJDA 3WAWA 3KD8A 4KJGA 3WAXA 5L0EA 5L0BA 5HRTA 2GSUA 5EGHA 5DLTA 3UN3A 4LRCA 3A52A 1KH7A 3CMRA 3IGZB 3OT9A 2VQRA 1ZEFA 3MK0A 3M8YA 1EJJA 2QZUA 3IGYB 3IDDA 4LR9A 3BDGA 3E2DA 1ALKA 1SHNA 1EQJA 2XR9A 2GSNA 1E2SP 4MY4A 2W5QA 3T01A 1K7HA 1ALHA 5C66A 3LXQA 2W5RA 3MK1A 1FSUA 4ZGAA 4UOOA 1P49A 1E33P 1KHKA 3DPCA 2IUCA 2GSOA 5EGEA 2W5SA 4GTYA 4KAYA 1Y7AA 3TWZA 3UN5A 4UOPA 1AJDA 3BDHA 3Q3QA 3TG0A 4YR1A 1Y6VA 5DLWA 4GTXA 1EI6A 5GOVA 1AJCA 5LRNA 4CYSA 3B5QA 3SZYA 3NKNA 5DLVA 3ED4A 4FDIA 3NVLA 4GTZA 4LR2A 5LRMA 1ALIA 2ZKTA 3M8WA 5LIAA 1HJKA 4CXUA 3UN2A 5AJ9A 4CYRA 2X98A 1KHLA 3BDGB 3NKOA 1ELZA 5KXAA 1O99A 2W5WA 1E1ZP 3T02A 2W5VA 1KH4A 1N2LA 1B8JA 1ANIA 4UPKA 1ZEDA 3WAYA 4ZG7A 1E3CP 1KH9A 1SHQA 3WAVA 4FDJA 5LQQA 4LR7A 4UPLA 4UPHA 3NKRA 4GTWA 1URBA 5TJ3A 4TN0A 4CXSA 2GA3A 3BDFA 3DYCA 1ELYA 4UORA 5INHA 1EW2A 4N7TA 1HDHA 1ELXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ANH A;  2W8D A;  1ED8 A;  3M8Z A;  1AJB A;  4LRD A;  4CXK A;  3WBH A;  1EW8 A;  4NWJ A;  4UPI A;  2G9Y A;  2RH6 A;  3SZZ A;  3UNY A;  3TX0 A;  5GRR A;  3NKM A;  2GLQ A;  4KAV A;  4KM4 A;  1KH5 A;  3T00 A;  1KHJ A;  4ZG9 A;  3MK2 A;  4NWX A;  5K4P A;  4LRA A;  1URA A;  2IUC B;  3UO0 A;  4LR8 A;  4MIV A;  1AJA A;  3NKP A;  4LRB A;  4B56 A;  5IJQ A;  4LQY A;  2W5X A;  1ALJ A;  1ANJ A;  1EW9 A;  2W5T A;  3M7V A;  3NKQ A;  4LRE A;  1HQA A;  5L0K A;  1AUK A;  4MHX A;  1KHN A;  2W8S A;  1ED9 A;  1ZEB A;  2IFY A;  2D1G A;  4QAX A;  2XRG A;  4ZG6 A;  4LRF A;  1N2K A;  1O98 A;  5IJS A;  4KJD A;  3WAW A;  3KD8 A;  4KJG A;  3WAX A;  5L0E A;  5L0B A;  5HRT A;  2GSU A;  5EGH A;  5DLT A;  3UN3 A;  4LRC A;  3A52 A;  1KH7 A;  3CMR A;  3IGZ B;  3OT9 A;  2VQR A;  1ZEF A;  3MK0 A;  3M8Y A;  1EJJ A;  2QZU A;  3IGY B;  3IDD A;  4LR9 A;  3BDG A;  3E2D A;  1ALK A;  1SHN A;  1EQJ A;  2XR9 A;  2GSN A;  1E2S P;  4MY4 A;  2W5Q A;  3T01 A;  1K7H A;  1ALH A;  5C66 A;  3LXQ A;  2W5R A;  3MK1 A;  1FSU A;  4ZGA A;  4UOO A;  1P49 A;  1E33 P;  1KHK A;  3DPC A;  2IUC A;  2GSO A;  5EGE A;  2W5S A;  4GTY A;  4KAY A;  1Y7A A;  3TWZ A;  3UN5 A;  4UOP A;  1AJD A;  3BDH A;  3Q3Q A;  3TG0 A;  4YR1 A;  1Y6V A;  5DLW A;  4GTX A;  1EI6 A;  5GOV A;  1AJC A;  5LRN A;  4CYS A;  3B5Q A;  3SZY A;  3NKN A;  5DLV A;  3ED4 A;  4FDI A;  3NVL A;  4GTZ A;  4LR2 A;  5LRM A;  1ALI A;  2ZKT A;  3M8W A;  5LIA A;  1HJK A;  4CXU A;  3UN2 A;  5AJ9 A;  4CYR A;  2X98 A;  1KHL A;  3BDG B;  3NKO A;  1ELZ A;  5KXA A;  1O99 A;  2W5W A;  1E1Z P;  3T02 A;  2W5V A;  1KH4 A;  1N2L A;  1B8J A;  1ANI A;  4UPK A;  1ZED A;  3WAY A;  4ZG7 A;  1E3C P;  1KH9 A;  1SHQ A;  3WAV A;  4FDJ A;  5LQQ A;  4LR7 A;  4UPL A;  4UPH A;  3NKR A;  4GTW A;  1URB A;  5TJ3 A;  4TN0 A;  4CXS A;  2GA3 A;  3BDF A;  3DYC A;  1ELY A;  4UOR A;  5INH A;  1EW2 A;  4N7T A;  1HDH A;  1ELX A; 
#chains in the Genus database with same CATH topology
 2ANH A;  2W8D A;  1ED8 A;  3M8Z A;  1AJB A;  4LRD A;  4CXK A;  3WBH A;  1EW8 A;  4NWJ A;  4UPI A;  2G9Y A;  2RH6 A;  3SZZ A;  3UNY A;  3TX0 A;  5GRR A;  3NKM A;  2GLQ A;  4KAV A;  4KM4 A;  1KH5 A;  3T00 A;  1KHJ A;  4ZG9 A;  3MK2 A;  4NWX A;  5K4P A;  4LRA A;  1URA A;  2IUC B;  3UO0 A;  4LR8 A;  4MIV A;  1AJA A;  3NKP A;  4LRB A;  4B56 A;  5IJQ A;  4LQY A;  2W5X A;  1ALJ A;  1ANJ A;  1EW9 A;  2W5T A;  3M7V A;  3NKQ A;  4LRE A;  1HQA A;  5L0K A;  1AUK A;  4MHX A;  1KHN A;  2W8S A;  1ED9 A;  1ZEB A;  2IFY A;  2D1G A;  4QAX A;  2XRG A;  4ZG6 A;  4LRF A;  1N2K A;  1O98 A;  5IJS A;  4KJD A;  3WAW A;  3KD8 A;  4KJG A;  3WAX A;  5L0E A;  5L0B A;  5HRT A;  2GSU A;  5EGH A;  5DLT A;  3UN3 A;  4LRC A;  3A52 A;  1KH7 A;  3CMR A;  3IGZ B;  3OT9 A;  2VQR A;  1ZEF A;  3MK0 A;  3M8Y A;  1EJJ A;  2QZU A;  3IGY B;  3IDD A;  4LR9 A;  3BDG A;  3E2D A;  1ALK A;  1SHN A;  1EQJ A;  2XR9 A;  2GSN A;  1E2S P;  4MY4 A;  2W5Q A;  3T01 A;  1K7H A;  1ALH A;  5C66 A;  3LXQ A;  2W5R A;  3MK1 A;  1FSU A;  4ZGA A;  4UOO A;  1P49 A;  1E33 P;  1KHK A;  3DPC A;  2IUC A;  2GSO A;  5EGE A;  2W5S A;  4GTY A;  4KAY A;  1Y7A A;  3TWZ A;  3UN5 A;  4UOP A;  1AJD A;  3BDH A;  3Q3Q A;  3TG0 A;  4YR1 A;  1Y6V A;  5DLW A;  4GTX A;  1EI6 A;  5GOV A;  1AJC A;  5LRN A;  4CYS A;  3B5Q A;  3SZY A;  3NKN A;  5DLV A;  3ED4 A;  4FDI A;  3NVL A;  4GTZ A;  4LR2 A;  5LRM A;  1ALI A;  2ZKT A;  3M8W A;  5LIA A;  1HJK A;  4CXU A;  3UN2 A;  5AJ9 A;  4CYR A;  2X98 A;  1KHL A;  3BDG B;  3NKO A;  1ELZ A;  5KXA A;  1O99 A;  2W5W A;  1E1Z P;  3T02 A;  2W5V A;  1KH4 A;  1N2L A;  1B8J A;  1ANI A;  4UPK A;  1ZED A;  3WAY A;  4ZG7 A;  1E3C P;  1KH9 A;  1SHQ A;  3WAV A;  4FDJ A;  5LQQ A;  4LR7 A;  4UPL A;  4UPH A;  3NKR A;  4GTW A;  1URB A;  5TJ3 A;  4TN0 A;  4CXS A;  2GA3 A;  3BDF A;  3DYC A;  1ELY A;  4UOR A;  5INH A;  1EW2 A;  4N7T A;  1HDH A;  1ELX A; 
#chains in the Genus database with same CATH homology
 2ANH A;  2W8D A;  1ED8 A;  3M8Z A;  1AJB A;  4LRD A;  4CXK A;  3WBH A;  1EW8 A;  4NWJ A;  4UPI A;  2G9Y A;  2RH6 A;  3SZZ A;  3UNY A;  3TX0 A;  5GRR A;  3NKM A;  2GLQ A;  4KAV A;  4KM4 A;  1KH5 A;  3T00 A;  1KHJ A;  4ZG9 A;  3MK2 A;  4NWX A;  5K4P A;  4LRA A;  1URA A;  2IUC B;  3UO0 A;  4LR8 A;  4MIV A;  1AJA A;  3NKP A;  4LRB A;  4B56 A;  5IJQ A;  4LQY A;  2W5X A;  1ALJ A;  1ANJ A;  1EW9 A;  2W5T A;  3M7V A;  3NKQ A;  4LRE A;  1HQA A;  5L0K A;  1AUK A;  4MHX A;  1KHN A;  2W8S A;  1ED9 A;  1ZEB A;  2IFY A;  2D1G A;  4QAX A;  2XRG A;  4ZG6 A;  4LRF A;  1N2K A;  1O98 A;  5IJS A;  4KJD A;  3WAW A;  3KD8 A;  4KJG A;  3WAX A;  5L0E A;  5L0B A;  5HRT A;  2GSU A;  5EGH A;  5DLT A;  3UN3 A;  4LRC A;  3A52 A;  1KH7 A;  3CMR A;  3IGZ B;  3OT9 A;  2VQR A;  1ZEF A;  3MK0 A;  3M8Y A;  1EJJ A;  2QZU A;  3IGY B;  3IDD A;  4LR9 A;  3BDG A;  3E2D A;  1ALK A;  1SHN A;  1EQJ A;  2XR9 A;  2GSN A;  1E2S P;  4MY4 A;  2W5Q A;  3T01 A;  1K7H A;  1ALH A;  5C66 A;  3LXQ A;  2W5R A;  3MK1 A;  1FSU A;  4ZGA A;  4UOO A;  1P49 A;  1E33 P;  1KHK A;  3DPC A;  2IUC A;  2GSO A;  5EGE A;  2W5S A;  4GTY A;  4KAY A;  1Y7A A;  3TWZ A;  3UN5 A;  4UOP A;  1AJD A;  3BDH A;  3Q3Q A;  3TG0 A;  4YR1 A;  1Y6V A;  5DLW A;  4GTX A;  1EI6 A;  5GOV A;  1AJC A;  5LRN A;  4CYS A;  3B5Q A;  3SZY A;  3NKN A;  5DLV A;  3ED4 A;  4FDI A;  3NVL A;  4GTZ A;  4LR2 A;  5LRM A;  1ALI A;  2ZKT A;  3M8W A;  5LIA A;  1HJK A;  4CXU A;  3UN2 A;  5AJ9 A;  4CYR A;  2X98 A;  1KHL A;  3BDG B;  3NKO A;  1ELZ A;  5KXA A;  1O99 A;  2W5W A;  1E1Z P;  3T02 A;  2W5V A;  1KH4 A;  1N2L A;  1B8J A;  1ANI A;  4UPK A;  1ZED A;  3WAY A;  4ZG7 A;  1E3C P;  1KH9 A;  1SHQ A;  3WAV A;  4FDJ A;  5LQQ A;  4LR7 A;  4UPL A;  4UPH A;  3NKR A;  4GTW A;  1URB A;  5TJ3 A;  4TN0 A;  4CXS A;  2GA3 A;  3BDF A;  3DYC A;  1ELY A;  4UOR A;  5INH A;  1EW2 A;  4N7T A;  1HDH A;  1ELX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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