2IUCB

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
Knots found
sequence length
346
structure length
342
Chain Sequence
QLKTPKNVILLISDGAGLSQISSTFYFKSGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNSIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRSDSKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMEKGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKSDGNTLVIVTSDHETGGFTLAAKSNKSEYSDYTEIGPTFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
molecule tags Hydrolase
source organism Antarctic bacterium tab5
molecule keywords ALKALINE PHOSPHATASE
total genus 125
structure length 342
sequence length 346
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucB00
4ZG6A 1Y7AA 1ED8A 4UPKA 3T01A 5DLVA 3IGYB 1E1ZP 2GLQA 1KHJA 1KH7A 1URAA 3WAVA 2W8SA 4LRDA 2W5XA 3MK0A 1ALIA 4MIVA 1AJDA 5LQQA 1EW2A 4QAXA 1AJAA 1ANJA 5KXAA 4CYRA 1SHNA 5DLTA 2QZUA 1HDHA 3WAYA 1P49A 3BDGB 1EW9A 4KM4A 4YR1A 5HRTA 3TG0A 3BDGA 3BDHA 5AJ9A 4LR9A 1AJBA 1ALKA 1Y6VA 3WAXA 4N7TA 2VQRA 1HQAA 2D1GA 4ZG9A 2XR9A 1E3CP 2IUCB 3MK2A 1E33P 4LREA 1ELXA 1KH5A 5EGHA 3M8YA 4KAYA 2W8DA 3MK1A 4LRBA 5DLWA 1EJJA 5IJQA 3M7VA 3UN5A 3IGZB 3NKQA 1EI6A 2W5VA 1K7HA 4TN0A 3WAWA 3DPCA 1KHNA 4GTXA 3NKMA 5GOVA 5TJ3A 3IDDA 2W5TA 4LR7A 4GTYA 3LXQA 2GSNA 1ALHA 2G9YA 3B5QA 4CXKA 1B8JA 2XRGA 3M8WA 4LR8A 4UOOA 4MHXA 1ZEDA 4NWJA 3BDFA 1AJCA 2IUCA 2ANHA 2GSOA 1URBA 3NKRA 2IFYA 1KH9A 3UO0A 5EGEA 3M8ZA 4MY4A 4UPLA 1KHKA 4KJDA 4ZGAA 5L0EA 5IJSA 4CYSA 4LR2A 4KAVA 3NKPA 5C66A 1ZEFA 2X98A 1KH4A 4UPHA 3TX0A 3KD8A 2W5QA 3NKNA 5GRRA 2GSUA 5LRMA 1ZEBA 1SHQA 4B56A 1N2KA 5L0BA 3NKOA 1KHLA 4GTZA 1AUKA 2GA3A 3DYCA 4UOPA 3TWZA 4LRAA 4UPIA 5INHA 3UNYA 1EQJA 4CXSA 4LRCA 1O99A 4LRFA 3UN3A 4FDJA 4CXUA 3E2DA 3ED4A 1ELZA 2RH6A 1ELYA 4LQYA 3A52A 3NVLA 1ANIA 4NWXA 2W5SA 3WBHA 5LIAA 3OT9A 5L0KA 1O98A 4GTWA 2W5RA 3CMRA 4KJGA 3T02A 4ZG7A 3SZYA 2W5WA 3SZZA 1EW8A 5LRNA 3Q3QA 3UN2A 1ED9A 1ALJA 5K4PA 1N2LA 2ZKTA 4UORA 1E2SP 1FSUA 1HJKA 3T00A 4FDIA
chains in the Genus database with same CATH superfamily
4ZG6A 1Y7AA 1ED8A 4UPKA 3T01A 5DLVA 3IGYB 1E1ZP 2GLQA 1KHJA 1KH7A 1URAA 3WAVA 2W8SA 4LRDA 2W5XA 3MK0A 1ALIA 4MIVA 1AJDA 5LQQA 1EW2A 4QAXA 1AJAA 1ANJA 5KXAA 4CYRA 1SHNA 5DLTA 2QZUA 1HDHA 3WAYA 1P49A 3BDGB 1EW9A 4KM4A 4YR1A 5HRTA 3TG0A 3BDGA 3BDHA 5AJ9A 4LR9A 1AJBA 1ALKA 1Y6VA 3WAXA 4N7TA 2VQRA 1HQAA 2D1GA 4ZG9A 2XR9A 1E3CP 2IUCB 3MK2A 1E33P 4LREA 1ELXA 1KH5A 5EGHA 3M8YA 4KAYA 2W8DA 3MK1A 4LRBA 5DLWA 1EJJA 5IJQA 3M7VA 3UN5A 3IGZB 3NKQA 1EI6A 2W5VA 1K7HA 4TN0A 3WAWA 3DPCA 1KHNA 4GTXA 3NKMA 5GOVA 5TJ3A 3IDDA 2W5TA 4LR7A 4GTYA 3LXQA 2GSNA 1ALHA 2G9YA 3B5QA 4CXKA 1B8JA 2XRGA 3M8WA 4LR8A 4UOOA 4MHXA 1ZEDA 4NWJA 3BDFA 1AJCA 2IUCA 2ANHA 2GSOA 1URBA 3NKRA 2IFYA 1KH9A 3UO0A 5EGEA 3M8ZA 4MY4A 4UPLA 1KHKA 4KJDA 4ZGAA 5L0EA 5IJSA 4CYSA 4LR2A 4KAVA 3NKPA 5C66A 1ZEFA 2X98A 1KH4A 4UPHA 3TX0A 3KD8A 2W5QA 3NKNA 5GRRA 2GSUA 5LRMA 1ZEBA 1SHQA 4B56A 1N2KA 5L0BA 3NKOA 1KHLA 4GTZA 1AUKA 2GA3A 3DYCA 4UOPA 3TWZA 4LRAA 4UPIA 5INHA 3UNYA 1EQJA 4CXSA 4LRCA 1O99A 4LRFA 3UN3A 4FDJA 4CXUA 3E2DA 3ED4A 1ELZA 2RH6A 1ELYA 4LQYA 3A52A 3NVLA 1ANIA 4NWXA 2W5SA 3WBHA 5LIAA 3OT9A 5L0KA 1O98A 4GTWA 2W5RA 3CMRA 4KJGA 3T02A 4ZG7A 3SZYA 2W5WA 3SZZA 1EW8A 5LRNA 3Q3QA 3UN2A 1ED9A 1ALJA 5K4PA 1N2LA 2ZKTA 4UORA 1E2SP 1FSUA 1HJKA 3T00A 4FDIA
chains in the Genus database with same CATH topology
4ZG6A 1Y7AA 1ED8A 4UPKA 3T01A 5DLVA 3IGYB 1E1ZP 2GLQA 1KHJA 1KH7A 1URAA 3WAVA 2W8SA 4LRDA 2W5XA 3MK0A 1ALIA 4MIVA 1AJDA 5LQQA 1EW2A 4QAXA 1AJAA 1ANJA 5KXAA 4CYRA 1SHNA 5DLTA 2QZUA 1HDHA 3WAYA 1P49A 3BDGB 1EW9A 4KM4A 4YR1A 5HRTA 3TG0A 3BDGA 3BDHA 5AJ9A 4LR9A 1AJBA 1ALKA 1Y6VA 3WAXA 4N7TA 2VQRA 1HQAA 2D1GA 4ZG9A 2XR9A 1E3CP 2IUCB 3MK2A 1E33P 4LREA 1ELXA 1KH5A 5EGHA 3M8YA 4KAYA 2W8DA 3MK1A 4LRBA 5DLWA 1EJJA 5IJQA 3M7VA 3UN5A 3IGZB 3NKQA 1EI6A 2W5VA 1K7HA 4TN0A 3WAWA 3DPCA 1KHNA 4GTXA 3NKMA 5GOVA 5TJ3A 3IDDA 2W5TA 4LR7A 4GTYA 3LXQA 2GSNA 1ALHA 2G9YA 3B5QA 4CXKA 1B8JA 2XRGA 3M8WA 4LR8A 4UOOA 4MHXA 1ZEDA 4NWJA 3BDFA 1AJCA 2IUCA 2ANHA 2GSOA 1URBA 3NKRA 2IFYA 1KH9A 3UO0A 5EGEA 3M8ZA 4MY4A 4UPLA 1KHKA 4KJDA 4ZGAA 5L0EA 5IJSA 4CYSA 4LR2A 4KAVA 3NKPA 5C66A 1ZEFA 2X98A 1KH4A 4UPHA 3TX0A 3KD8A 2W5QA 3NKNA 5GRRA 2GSUA 5LRMA 1ZEBA 1SHQA 4B56A 1N2KA 5L0BA 3NKOA 1KHLA 4GTZA 1AUKA 2GA3A 3DYCA 4UOPA 3TWZA 4LRAA 4UPIA 5INHA 3UNYA 1EQJA 4CXSA 4LRCA 1O99A 4LRFA 3UN3A 4FDJA 4CXUA 3E2DA 3ED4A 1ELZA 2RH6A 1ELYA 4LQYA 3A52A 3NVLA 1ANIA 4NWXA 2W5SA 3WBHA 5LIAA 3OT9A 5L0KA 1O98A 4GTWA 2W5RA 3CMRA 4KJGA 3T02A 4ZG7A 3SZYA 2W5WA 3SZZA 1EW8A 5LRNA 3Q3QA 3UN2A 1ED9A 1ALJA 5K4PA 1N2LA 2ZKTA 4UORA 1E2SP 1FSUA 1HJKA 3T00A 4FDIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZG6 A;  1Y7A A;  1ED8 A;  4UPK A;  3T01 A;  5DLV A;  3IGY B;  1E1Z P;  2GLQ A;  1KHJ A;  1KH7 A;  1URA A;  3WAV A;  2W8S A;  4LRD A;  2W5X A;  3MK0 A;  1ALI A;  4MIV A;  1AJD A;  5LQQ A;  1EW2 A;  4QAX A;  1AJA A;  1ANJ A;  5KXA A;  4CYR A;  1SHN A;  5DLT A;  2QZU A;  1HDH A;  3WAY A;  1P49 A;  3BDG B;  1EW9 A;  4KM4 A;  4YR1 A;  5HRT A;  3TG0 A;  3BDG A;  3BDH A;  5AJ9 A;  4LR9 A;  1AJB A;  1ALK A;  1Y6V A;  3WAX A;  4N7T A;  2VQR A;  1HQA A;  2D1G A;  4ZG9 A;  2XR9 A;  1E3C P;  2IUC B;  3MK2 A;  1E33 P;  4LRE A;  1ELX A;  1KH5 A;  5EGH A;  3M8Y A;  4KAY A;  2W8D A;  3MK1 A;  4LRB A;  5DLW A;  1EJJ A;  5IJQ A;  3M7V A;  3UN5 A;  3IGZ B;  3NKQ A;  1EI6 A;  2W5V A;  1K7H A;  4TN0 A;  3WAW A;  3DPC A;  1KHN A;  4GTX A;  3NKM A;  5GOV A;  5TJ3 A;  3IDD A;  2W5T A;  4LR7 A;  4GTY A;  3LXQ A;  2GSN A;  1ALH A;  2G9Y A;  3B5Q A;  4CXK A;  1B8J A;  2XRG A;  3M8W A;  4LR8 A;  4UOO A;  4MHX A;  1ZED A;  4NWJ A;  3BDF A;  1AJC A;  2IUC A;  2ANH A;  2GSO A;  1URB A;  3NKR A;  2IFY A;  1KH9 A;  3UO0 A;  5EGE A;  3M8Z A;  4MY4 A;  4UPL A;  1KHK A;  4KJD A;  4ZGA A;  5L0E A;  5IJS A;  4CYS A;  4LR2 A;  4KAV A;  3NKP A;  5C66 A;  1ZEF A;  2X98 A;  1KH4 A;  4UPH A;  3TX0 A;  3KD8 A;  2W5Q A;  3NKN A;  5GRR A;  2GSU A;  5LRM A;  1ZEB A;  1SHQ A;  4B56 A;  1N2K A;  5L0B A;  3NKO A;  1KHL A;  4GTZ A;  1AUK A;  2GA3 A;  3DYC A;  4UOP A;  3TWZ A;  4LRA A;  4UPI A;  5INH A;  3UNY A;  1EQJ A;  4CXS A;  4LRC A;  1O99 A;  4LRF A;  3UN3 A;  4FDJ A;  4CXU A;  3E2D A;  3ED4 A;  1ELZ A;  2RH6 A;  1ELY A;  4LQY A;  3A52 A;  3NVL A;  1ANI A;  4NWX A;  2W5S A;  3WBH A;  5LIA A;  3OT9 A;  5L0K A;  1O98 A;  4GTW A;  2W5R A;  3CMR A;  4KJG A;  3T02 A;  4ZG7 A;  3SZY A;  2W5W A;  3SZZ A;  1EW8 A;  5LRN A;  3Q3Q A;  3UN2 A;  1ED9 A;  1ALJ A;  5K4P A;  1N2L A;  2ZKT A;  4UOR A;  1E2S P;  1FSU A;  1HJK A;  3T00 A;  4FDI A; 
#chains in the Genus database with same CATH topology
 4ZG6 A;  1Y7A A;  1ED8 A;  4UPK A;  3T01 A;  5DLV A;  3IGY B;  1E1Z P;  2GLQ A;  1KHJ A;  1KH7 A;  1URA A;  3WAV A;  2W8S A;  4LRD A;  2W5X A;  3MK0 A;  1ALI A;  4MIV A;  1AJD A;  5LQQ A;  1EW2 A;  4QAX A;  1AJA A;  1ANJ A;  5KXA A;  4CYR A;  1SHN A;  5DLT A;  2QZU A;  1HDH A;  3WAY A;  1P49 A;  3BDG B;  1EW9 A;  4KM4 A;  4YR1 A;  5HRT A;  3TG0 A;  3BDG A;  3BDH A;  5AJ9 A;  4LR9 A;  1AJB A;  1ALK A;  1Y6V A;  3WAX A;  4N7T A;  2VQR A;  1HQA A;  2D1G A;  4ZG9 A;  2XR9 A;  1E3C P;  2IUC B;  3MK2 A;  1E33 P;  4LRE A;  1ELX A;  1KH5 A;  5EGH A;  3M8Y A;  4KAY A;  2W8D A;  3MK1 A;  4LRB A;  5DLW A;  1EJJ A;  5IJQ A;  3M7V A;  3UN5 A;  3IGZ B;  3NKQ A;  1EI6 A;  2W5V A;  1K7H A;  4TN0 A;  3WAW A;  3DPC A;  1KHN A;  4GTX A;  3NKM A;  5GOV A;  5TJ3 A;  3IDD A;  2W5T A;  4LR7 A;  4GTY A;  3LXQ A;  2GSN A;  1ALH A;  2G9Y A;  3B5Q A;  4CXK A;  1B8J A;  2XRG A;  3M8W A;  4LR8 A;  4UOO A;  4MHX A;  1ZED A;  4NWJ A;  3BDF A;  1AJC A;  2IUC A;  2ANH A;  2GSO A;  1URB A;  3NKR A;  2IFY A;  1KH9 A;  3UO0 A;  5EGE A;  3M8Z A;  4MY4 A;  4UPL A;  1KHK A;  4KJD A;  4ZGA A;  5L0E A;  5IJS A;  4CYS A;  4LR2 A;  4KAV A;  3NKP A;  5C66 A;  1ZEF A;  2X98 A;  1KH4 A;  4UPH A;  3TX0 A;  3KD8 A;  2W5Q A;  3NKN A;  5GRR A;  2GSU A;  5LRM A;  1ZEB A;  1SHQ A;  4B56 A;  1N2K A;  5L0B A;  3NKO A;  1KHL A;  4GTZ A;  1AUK A;  2GA3 A;  3DYC A;  4UOP A;  3TWZ A;  4LRA A;  4UPI A;  5INH A;  3UNY A;  1EQJ A;  4CXS A;  4LRC A;  1O99 A;  4LRF A;  3UN3 A;  4FDJ A;  4CXU A;  3E2D A;  3ED4 A;  1ELZ A;  2RH6 A;  1ELY A;  4LQY A;  3A52 A;  3NVL A;  1ANI A;  4NWX A;  2W5S A;  3WBH A;  5LIA A;  3OT9 A;  5L0K A;  1O98 A;  4GTW A;  2W5R A;  3CMR A;  4KJG A;  3T02 A;  4ZG7 A;  3SZY A;  2W5W A;  3SZZ A;  1EW8 A;  5LRN A;  3Q3Q A;  3UN2 A;  1ED9 A;  1ALJ A;  5K4P A;  1N2L A;  2ZKT A;  4UOR A;  1E2S P;  1FSU A;  1HJK A;  3T00 A;  4FDI A; 
#chains in the Genus database with same CATH homology
 4ZG6 A;  1Y7A A;  1ED8 A;  4UPK A;  3T01 A;  5DLV A;  3IGY B;  1E1Z P;  2GLQ A;  1KHJ A;  1KH7 A;  1URA A;  3WAV A;  2W8S A;  4LRD A;  2W5X A;  3MK0 A;  1ALI A;  4MIV A;  1AJD A;  5LQQ A;  1EW2 A;  4QAX A;  1AJA A;  1ANJ A;  5KXA A;  4CYR A;  1SHN A;  5DLT A;  2QZU A;  1HDH A;  3WAY A;  1P49 A;  3BDG B;  1EW9 A;  4KM4 A;  4YR1 A;  5HRT A;  3TG0 A;  3BDG A;  3BDH A;  5AJ9 A;  4LR9 A;  1AJB A;  1ALK A;  1Y6V A;  3WAX A;  4N7T A;  2VQR A;  1HQA A;  2D1G A;  4ZG9 A;  2XR9 A;  1E3C P;  2IUC B;  3MK2 A;  1E33 P;  4LRE A;  1ELX A;  1KH5 A;  5EGH A;  3M8Y A;  4KAY A;  2W8D A;  3MK1 A;  4LRB A;  5DLW A;  1EJJ A;  5IJQ A;  3M7V A;  3UN5 A;  3IGZ B;  3NKQ A;  1EI6 A;  2W5V A;  1K7H A;  4TN0 A;  3WAW A;  3DPC A;  1KHN A;  4GTX A;  3NKM A;  5GOV A;  5TJ3 A;  3IDD A;  2W5T A;  4LR7 A;  4GTY A;  3LXQ A;  2GSN A;  1ALH A;  2G9Y A;  3B5Q A;  4CXK A;  1B8J A;  2XRG A;  3M8W A;  4LR8 A;  4UOO A;  4MHX A;  1ZED A;  4NWJ A;  3BDF A;  1AJC A;  2IUC A;  2ANH A;  2GSO A;  1URB A;  3NKR A;  2IFY A;  1KH9 A;  3UO0 A;  5EGE A;  3M8Z A;  4MY4 A;  4UPL A;  1KHK A;  4KJD A;  4ZGA A;  5L0E A;  5IJS A;  4CYS A;  4LR2 A;  4KAV A;  3NKP A;  5C66 A;  1ZEF A;  2X98 A;  1KH4 A;  4UPH A;  3TX0 A;  3KD8 A;  2W5Q A;  3NKN A;  5GRR A;  2GSU A;  5LRM A;  1ZEB A;  1SHQ A;  4B56 A;  1N2K A;  5L0B A;  3NKO A;  1KHL A;  4GTZ A;  1AUK A;  2GA3 A;  3DYC A;  4UOP A;  3TWZ A;  4LRA A;  4UPI A;  5INH A;  3UNY A;  1EQJ A;  4CXS A;  4LRC A;  1O99 A;  4LRF A;  3UN3 A;  4FDJ A;  4CXU A;  3E2D A;  3ED4 A;  1ELZ A;  2RH6 A;  1ELY A;  4LQY A;  3A52 A;  3NVL A;  1ANI A;  4NWX A;  2W5S A;  3WBH A;  5LIA A;  3OT9 A;  5L0K A;  1O98 A;  4GTW A;  2W5R A;  3CMR A;  4KJG A;  3T02 A;  4ZG7 A;  3SZY A;  2W5W A;  3SZZ A;  1EW8 A;  5LRN A;  3Q3Q A;  3UN2 A;  1ED9 A;  1ALJ A;  5K4P A;  1N2L A;  2ZKT A;  4UOR A;  1E2S P;  1FSU A;  1HJK A;  3T00 A;  4FDI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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