3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
Knots found
sequence length
449
structure length
449
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Alkaline phosphatase
total genus 147
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
1HJKA 1EI6A 4KM4A 3M8ZA 5GOVA 5DLTA 1ED9A 3OT9A 3UO0A 3TX0A 2IUCB 3ED4A 3UN3A 3WBHA 1KHNA 4LRBA 1HDHA 4GTWA 3SZZA 5INHA 2IFYA 4NWJA 2G9YA 5IJSA 2ANHA 4UPIA 1P49A 2D1GA 5EGHA 3UN2A 1URBA 2W5TA 3BDFA 4FDIA 3BDGA 2GLQA 3LXQA 4LRDA 1ALKA 5TJ3A 1ELZA 5GRRA 1KH9A 1ANJA 4YR1A 1E1ZP 4LRFA 1FSUA 4CXSA 1AUKA 3UNYA 2W5WA 2RH6A 4QAXA 4KAYA 4LREA 2ZKTA 5LQQA 3NVLA 5AJ9A 2IUCA 3Q3QA 4ZG7A 1ALHA 3NKOA 3B5QA 3CMRA 1URAA 2GSUA 4KJDA 5L0KA 3DPCA 1ZEDA 1HQAA 2VQRA 4ZGAA 4LR7A 3E2DA 4MY4A 1KHKA 1KH4A 4CXUA 1EW9A 3DYCA 3NKMA 2W5RA 4CYRA 4KJGA 1ANIA 1E33P 1KH5A 5DLWA 4LR8A 4MHXA 1KHJA 3M7VA 4LQYA 1AJAA 3WAXA 3SZYA 5L0BA 2GSOA 1EW8A 4LR2A 5IJQA 1ED8A 4GTYA 4KAVA 1O99A 5K4PA 1ALJA 4LRAA 3BDHA 1E2SP 3MK2A 4LR9A 4LRCA 4UOPA 4UORA 2W5SA 1O98A 3NKRA 1SHNA 2W5QA 1EJJA 3T01A 4UOOA 2XR9A 4ZG6A 3TWZA 4UPLA 1E3CP 1ZEFA 3T02A 1ELYA 3MK1A 3IGZB 3IGYB 3WAWA 5EGEA 1AJCA 5DLVA 5LIAA 4ZG9A 5HRTA 3IDDA 1AJDA 2W8DA 1SHQA 3NKNA 2QZUA 4NWXA 2W8SA 3UN5A 5LRMA 4GTXA 1Y6VA 5C66A 5LRNA 4CXKA 3TG0A 3T00A 3WAYA 3WAVA 1B8JA 1ELXA 3M8WA 4FDJA 4UPHA 5L0EA 1KH7A 1KHLA 1AJBA 1EQJA 2X98A 2W5XA 1K7HA 4MIVA 4B56A 2XRGA 2GA3A 3BDGB 4GTZA 3NKPA 1ZEBA 1N2KA 3MK0A 3A52A 4N7TA 4TN0A 4CYSA 3NKQA 3M8YA 1EW2A 1ALIA 2GSNA 3KD8A 4UPKA 5KXAA 2W5VA 1Y7AA 1N2LA
chains in the Genus database with same CATH superfamily
1HJKA 1EI6A 4KM4A 3M8ZA 5GOVA 5DLTA 1ED9A 3OT9A 3UO0A 3TX0A 2IUCB 3ED4A 3UN3A 3WBHA 1KHNA 4LRBA 1HDHA 4GTWA 3SZZA 5INHA 2IFYA 4NWJA 2G9YA 5IJSA 2ANHA 4UPIA 1P49A 2D1GA 5EGHA 3UN2A 1URBA 2W5TA 3BDFA 4FDIA 3BDGA 2GLQA 3LXQA 4LRDA 1ALKA 5TJ3A 1ELZA 5GRRA 1KH9A 1ANJA 4YR1A 1E1ZP 4LRFA 1FSUA 4CXSA 1AUKA 3UNYA 2W5WA 2RH6A 4QAXA 4KAYA 4LREA 2ZKTA 5LQQA 3NVLA 5AJ9A 2IUCA 3Q3QA 4ZG7A 1ALHA 3NKOA 3B5QA 3CMRA 1URAA 2GSUA 4KJDA 5L0KA 3DPCA 1ZEDA 1HQAA 2VQRA 4ZGAA 4LR7A 3E2DA 4MY4A 1KHKA 1KH4A 4CXUA 1EW9A 3DYCA 3NKMA 2W5RA 4CYRA 4KJGA 1ANIA 1E33P 1KH5A 5DLWA 4LR8A 4MHXA 1KHJA 3M7VA 4LQYA 1AJAA 3WAXA 3SZYA 5L0BA 2GSOA 1EW8A 4LR2A 5IJQA 1ED8A 4GTYA 4KAVA 1O99A 5K4PA 1ALJA 4LRAA 3BDHA 1E2SP 3MK2A 4LR9A 4LRCA 4UOPA 4UORA 2W5SA 1O98A 3NKRA 1SHNA 2W5QA 1EJJA 3T01A 4UOOA 2XR9A 4ZG6A 3TWZA 4UPLA 1E3CP 1ZEFA 3T02A 1ELYA 3MK1A 3IGZB 3IGYB 3WAWA 5EGEA 1AJCA 5DLVA 5LIAA 4ZG9A 5HRTA 3IDDA 1AJDA 2W8DA 1SHQA 3NKNA 2QZUA 4NWXA 2W8SA 3UN5A 5LRMA 4GTXA 1Y6VA 5C66A 5LRNA 4CXKA 3TG0A 3T00A 3WAYA 3WAVA 1B8JA 1ELXA 3M8WA 4FDJA 4UPHA 5L0EA 1KH7A 1KHLA 1AJBA 1EQJA 2X98A 2W5XA 1K7HA 4MIVA 4B56A 2XRGA 2GA3A 3BDGB 4GTZA 3NKPA 1ZEBA 1N2KA 3MK0A 3A52A 4N7TA 4TN0A 4CYSA 3NKQA 3M8YA 1EW2A 1ALIA 2GSNA 3KD8A 4UPKA 5KXAA 2W5VA 1Y7AA 1N2LA
chains in the Genus database with same CATH topology
1HJKA 1EI6A 4KM4A 3M8ZA 5GOVA 5DLTA 1ED9A 3OT9A 3UO0A 3TX0A 2IUCB 3ED4A 3UN3A 3WBHA 1KHNA 4LRBA 1HDHA 4GTWA 3SZZA 5INHA 2IFYA 4NWJA 2G9YA 5IJSA 2ANHA 4UPIA 1P49A 2D1GA 5EGHA 3UN2A 1URBA 2W5TA 3BDFA 4FDIA 3BDGA 2GLQA 3LXQA 4LRDA 1ALKA 5TJ3A 1ELZA 5GRRA 1KH9A 1ANJA 4YR1A 1E1ZP 4LRFA 1FSUA 4CXSA 1AUKA 3UNYA 2W5WA 2RH6A 4QAXA 4KAYA 4LREA 2ZKTA 5LQQA 3NVLA 5AJ9A 2IUCA 3Q3QA 4ZG7A 1ALHA 3NKOA 3B5QA 3CMRA 1URAA 2GSUA 4KJDA 5L0KA 3DPCA 1ZEDA 1HQAA 2VQRA 4ZGAA 4LR7A 3E2DA 4MY4A 1KHKA 1KH4A 4CXUA 1EW9A 3DYCA 3NKMA 2W5RA 4CYRA 4KJGA 1ANIA 1E33P 1KH5A 5DLWA 4LR8A 4MHXA 1KHJA 3M7VA 4LQYA 1AJAA 3WAXA 3SZYA 5L0BA 2GSOA 1EW8A 4LR2A 5IJQA 1ED8A 4GTYA 4KAVA 1O99A 5K4PA 1ALJA 4LRAA 3BDHA 1E2SP 3MK2A 4LR9A 4LRCA 4UOPA 4UORA 2W5SA 1O98A 3NKRA 1SHNA 2W5QA 1EJJA 3T01A 4UOOA 2XR9A 4ZG6A 3TWZA 4UPLA 1E3CP 1ZEFA 3T02A 1ELYA 3MK1A 3IGZB 3IGYB 3WAWA 5EGEA 1AJCA 5DLVA 5LIAA 4ZG9A 5HRTA 3IDDA 1AJDA 2W8DA 1SHQA 3NKNA 2QZUA 4NWXA 2W8SA 3UN5A 5LRMA 4GTXA 1Y6VA 5C66A 5LRNA 4CXKA 3TG0A 3T00A 3WAYA 3WAVA 1B8JA 1ELXA 3M8WA 4FDJA 4UPHA 5L0EA 1KH7A 1KHLA 1AJBA 1EQJA 2X98A 2W5XA 1K7HA 4MIVA 4B56A 2XRGA 2GA3A 3BDGB 4GTZA 3NKPA 1ZEBA 1N2KA 3MK0A 3A52A 4N7TA 4TN0A 4CYSA 3NKQA 3M8YA 1EW2A 1ALIA 2GSNA 3KD8A 4UPKA 5KXAA 2W5VA 1Y7AA 1N2LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HJK A;  1EI6 A;  4KM4 A;  3M8Z A;  5GOV A;  5DLT A;  1ED9 A;  3OT9 A;  3UO0 A;  3TX0 A;  2IUC B;  3ED4 A;  3UN3 A;  3WBH A;  1KHN A;  4LRB A;  1HDH A;  4GTW A;  3SZZ A;  5INH A;  2IFY A;  4NWJ A;  2G9Y A;  5IJS A;  2ANH A;  4UPI A;  1P49 A;  2D1G A;  5EGH A;  3UN2 A;  1URB A;  2W5T A;  3BDF A;  4FDI A;  3BDG A;  2GLQ A;  3LXQ A;  4LRD A;  1ALK A;  5TJ3 A;  1ELZ A;  5GRR A;  1KH9 A;  1ANJ A;  4YR1 A;  1E1Z P;  4LRF A;  1FSU A;  4CXS A;  1AUK A;  3UNY A;  2W5W A;  2RH6 A;  4QAX A;  4KAY A;  4LRE A;  2ZKT A;  5LQQ A;  3NVL A;  5AJ9 A;  2IUC A;  3Q3Q A;  4ZG7 A;  1ALH A;  3NKO A;  3B5Q A;  3CMR A;  1URA A;  2GSU A;  4KJD A;  5L0K A;  3DPC A;  1ZED A;  1HQA A;  2VQR A;  4ZGA A;  4LR7 A;  3E2D A;  4MY4 A;  1KHK A;  1KH4 A;  4CXU A;  1EW9 A;  3DYC A;  3NKM A;  2W5R A;  4CYR A;  4KJG A;  1ANI A;  1E33 P;  1KH5 A;  5DLW A;  4LR8 A;  4MHX A;  1KHJ A;  3M7V A;  4LQY A;  1AJA A;  3WAX A;  3SZY A;  5L0B A;  2GSO A;  1EW8 A;  4LR2 A;  5IJQ A;  1ED8 A;  4GTY A;  4KAV A;  1O99 A;  5K4P A;  1ALJ A;  4LRA A;  3BDH A;  1E2S P;  3MK2 A;  4LR9 A;  4LRC A;  4UOP A;  4UOR A;  2W5S A;  1O98 A;  3NKR A;  1SHN A;  2W5Q A;  1EJJ A;  3T01 A;  4UOO A;  2XR9 A;  4ZG6 A;  3TWZ A;  4UPL A;  1E3C P;  1ZEF A;  3T02 A;  1ELY A;  3MK1 A;  3IGZ B;  3IGY B;  3WAW A;  5EGE A;  1AJC A;  5DLV A;  5LIA A;  4ZG9 A;  5HRT A;  3IDD A;  1AJD A;  2W8D A;  1SHQ A;  3NKN A;  2QZU A;  4NWX A;  2W8S A;  3UN5 A;  5LRM A;  4GTX A;  1Y6V A;  5C66 A;  5LRN A;  4CXK A;  3TG0 A;  3T00 A;  3WAY A;  3WAV A;  1B8J A;  1ELX A;  3M8W A;  4FDJ A;  4UPH A;  5L0E A;  1KH7 A;  1KHL A;  1AJB A;  1EQJ A;  2X98 A;  2W5X A;  1K7H A;  4MIV A;  4B56 A;  2XRG A;  2GA3 A;  3BDG B;  4GTZ A;  3NKP A;  1ZEB A;  1N2K A;  3MK0 A;  3A52 A;  4N7T A;  4TN0 A;  4CYS A;  3NKQ A;  3M8Y A;  1EW2 A;  1ALI A;  2GSN A;  3KD8 A;  4UPK A;  5KXA A;  2W5V A;  1Y7A A;  1N2L A; 
#chains in the Genus database with same CATH topology
 1HJK A;  1EI6 A;  4KM4 A;  3M8Z A;  5GOV A;  5DLT A;  1ED9 A;  3OT9 A;  3UO0 A;  3TX0 A;  2IUC B;  3ED4 A;  3UN3 A;  3WBH A;  1KHN A;  4LRB A;  1HDH A;  4GTW A;  3SZZ A;  5INH A;  2IFY A;  4NWJ A;  2G9Y A;  5IJS A;  2ANH A;  4UPI A;  1P49 A;  2D1G A;  5EGH A;  3UN2 A;  1URB A;  2W5T A;  3BDF A;  4FDI A;  3BDG A;  2GLQ A;  3LXQ A;  4LRD A;  1ALK A;  5TJ3 A;  1ELZ A;  5GRR A;  1KH9 A;  1ANJ A;  4YR1 A;  1E1Z P;  4LRF A;  1FSU A;  4CXS A;  1AUK A;  3UNY A;  2W5W A;  2RH6 A;  4QAX A;  4KAY A;  4LRE A;  2ZKT A;  5LQQ A;  3NVL A;  5AJ9 A;  2IUC A;  3Q3Q A;  4ZG7 A;  1ALH A;  3NKO A;  3B5Q A;  3CMR A;  1URA A;  2GSU A;  4KJD A;  5L0K A;  3DPC A;  1ZED A;  1HQA A;  2VQR A;  4ZGA A;  4LR7 A;  3E2D A;  4MY4 A;  1KHK A;  1KH4 A;  4CXU A;  1EW9 A;  3DYC A;  3NKM A;  2W5R A;  4CYR A;  4KJG A;  1ANI A;  1E33 P;  1KH5 A;  5DLW A;  4LR8 A;  4MHX A;  1KHJ A;  3M7V A;  4LQY A;  1AJA A;  3WAX A;  3SZY A;  5L0B A;  2GSO A;  1EW8 A;  4LR2 A;  5IJQ A;  1ED8 A;  4GTY A;  4KAV A;  1O99 A;  5K4P A;  1ALJ A;  4LRA A;  3BDH A;  1E2S P;  3MK2 A;  4LR9 A;  4LRC A;  4UOP A;  4UOR A;  2W5S A;  1O98 A;  3NKR A;  1SHN A;  2W5Q A;  1EJJ A;  3T01 A;  4UOO A;  2XR9 A;  4ZG6 A;  3TWZ A;  4UPL A;  1E3C P;  1ZEF A;  3T02 A;  1ELY A;  3MK1 A;  3IGZ B;  3IGY B;  3WAW A;  5EGE A;  1AJC A;  5DLV A;  5LIA A;  4ZG9 A;  5HRT A;  3IDD A;  1AJD A;  2W8D A;  1SHQ A;  3NKN A;  2QZU A;  4NWX A;  2W8S A;  3UN5 A;  5LRM A;  4GTX A;  1Y6V A;  5C66 A;  5LRN A;  4CXK A;  3TG0 A;  3T00 A;  3WAY A;  3WAV A;  1B8J A;  1ELX A;  3M8W A;  4FDJ A;  4UPH A;  5L0E A;  1KH7 A;  1KHL A;  1AJB A;  1EQJ A;  2X98 A;  2W5X A;  1K7H A;  4MIV A;  4B56 A;  2XRG A;  2GA3 A;  3BDG B;  4GTZ A;  3NKP A;  1ZEB A;  1N2K A;  3MK0 A;  3A52 A;  4N7T A;  4TN0 A;  4CYS A;  3NKQ A;  3M8Y A;  1EW2 A;  1ALI A;  2GSN A;  3KD8 A;  4UPK A;  5KXA A;  2W5V A;  1Y7A A;  1N2L A; 
#chains in the Genus database with same CATH homology
 1HJK A;  1EI6 A;  4KM4 A;  3M8Z A;  5GOV A;  5DLT A;  1ED9 A;  3OT9 A;  3UO0 A;  3TX0 A;  2IUC B;  3ED4 A;  3UN3 A;  3WBH A;  1KHN A;  4LRB A;  1HDH A;  4GTW A;  3SZZ A;  5INH A;  2IFY A;  4NWJ A;  2G9Y A;  5IJS A;  2ANH A;  4UPI A;  1P49 A;  2D1G A;  5EGH A;  3UN2 A;  1URB A;  2W5T A;  3BDF A;  4FDI A;  3BDG A;  2GLQ A;  3LXQ A;  4LRD A;  1ALK A;  5TJ3 A;  1ELZ A;  5GRR A;  1KH9 A;  1ANJ A;  4YR1 A;  1E1Z P;  4LRF A;  1FSU A;  4CXS A;  1AUK A;  3UNY A;  2W5W A;  2RH6 A;  4QAX A;  4KAY A;  4LRE A;  2ZKT A;  5LQQ A;  3NVL A;  5AJ9 A;  2IUC A;  3Q3Q A;  4ZG7 A;  1ALH A;  3NKO A;  3B5Q A;  3CMR A;  1URA A;  2GSU A;  4KJD A;  5L0K A;  3DPC A;  1ZED A;  1HQA A;  2VQR A;  4ZGA A;  4LR7 A;  3E2D A;  4MY4 A;  1KHK A;  1KH4 A;  4CXU A;  1EW9 A;  3DYC A;  3NKM A;  2W5R A;  4CYR A;  4KJG A;  1ANI A;  1E33 P;  1KH5 A;  5DLW A;  4LR8 A;  4MHX A;  1KHJ A;  3M7V A;  4LQY A;  1AJA A;  3WAX A;  3SZY A;  5L0B A;  2GSO A;  1EW8 A;  4LR2 A;  5IJQ A;  1ED8 A;  4GTY A;  4KAV A;  1O99 A;  5K4P A;  1ALJ A;  4LRA A;  3BDH A;  1E2S P;  3MK2 A;  4LR9 A;  4LRC A;  4UOP A;  4UOR A;  2W5S A;  1O98 A;  3NKR A;  1SHN A;  2W5Q A;  1EJJ A;  3T01 A;  4UOO A;  2XR9 A;  4ZG6 A;  3TWZ A;  4UPL A;  1E3C P;  1ZEF A;  3T02 A;  1ELY A;  3MK1 A;  3IGZ B;  3IGY B;  3WAW A;  5EGE A;  1AJC A;  5DLV A;  5LIA A;  4ZG9 A;  5HRT A;  3IDD A;  1AJD A;  2W8D A;  1SHQ A;  3NKN A;  2QZU A;  4NWX A;  2W8S A;  3UN5 A;  5LRM A;  4GTX A;  1Y6V A;  5C66 A;  5LRN A;  4CXK A;  3TG0 A;  3T00 A;  3WAY A;  3WAV A;  1B8J A;  1ELX A;  3M8W A;  4FDJ A;  4UPH A;  5L0E A;  1KH7 A;  1KHL A;  1AJB A;  1EQJ A;  2X98 A;  2W5X A;  1K7H A;  4MIV A;  4B56 A;  2XRG A;  2GA3 A;  3BDG B;  4GTZ A;  3NKP A;  1ZEB A;  1N2K A;  3MK0 A;  3A52 A;  4N7T A;  4TN0 A;  4CYS A;  3NKQ A;  3M8Y A;  1EW2 A;  1ALI A;  2GSN A;  3KD8 A;  4UPK A;  5KXA A;  2W5V A;  1Y7A A;  1N2L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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