3DYCA

Structure of e322y alkaline phosphatase in complex with inorganic phosphate
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
Knots found
sequence length
446
structure length
446
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVYGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Alkaline phosphatase
total genus 156
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dycA00
2GSOA 4UOPA 1EQJA 4UPIA 3NKRA 3TX0A 5KXAA 2W5SA 4LRAA 2QZUA 4LRFA 1EJJA 4GTYA 3UN3A 4CXUA 3NKMA 2G9YA 4B56A 1Y6VA 3SZYA 1ELZA 5EGHA 2D1GA 5DLVA 2GLQA 4LRCA 5EGEA 3BDFA 3MK0A 4KJGA 5L0EA 3DYCA 3M8ZA 3ED4A 5HRTA 3SZZA 3Q3QA 3T01A 3M8WA 3NVLA 1E1ZP 1AJAA 1ED8A 4LRBA 3WBHA 1E2SP 2IFYA 3NKOA 1ZEFA 1ALKA 3BDGB 3T00A 3IGZB 1B8JA 4LR7A 1ALHA 3UNYA 4TN0A 1KHKA 1Y7AA 3NKNA 4GTXA 3LXQA 4CYSA 5DLTA 3IGYB 3UN2A 1ELXA 1O99A 4FDJA 2X98A 3MK1A 1HDHA 4ZG7A 5GRRA 2W5VA 1AJBA 1SHNA 4LRDA 2GSUA 3DPCA 4MY4A 5K4PA 5LRMA 1E33P 4KJDA 4LQYA 1ANIA 3B5QA 5C66A 5DLWA 1ALJA 1ANJA 2W5QA 2W8SA 4KM4A 3UN5A 2RH6A 2IUCA 4KAVA 4LR2A 3TWZA 3CMRA 3WAVA 4UOOA 1KHNA 1N2LA 2GSNA 5LQQA 4N7TA 4FDIA 5IJSA 2XRGA 4NWXA 1KH9A 4ZG9A 4KAYA 2GA3A 4MIVA 1EW2A 3IDDA 4MHXA 4ZGAA 1ALIA 5LIAA 2W5XA 1P49A 3E2DA 3TG0A 4UPLA 4LR8A 1URAA 4ZG6A 3BDHA 1ELYA 1AJCA 1HQAA 4CYRA 5IJQA 5INHA 3NKPA 3MK2A 3OT9A 3M7VA 3A52A 4UPHA 5GOVA 3M8YA 5LRNA 5L0KA 1EI6A 4LREA 5AJ9A 5TJ3A 2ZKTA 2W5TA 1KHJA 3UO0A 1E3CP 1AJDA 1ZEDA 1KH7A 1EW9A 3WAYA 4CXKA 3NKQA 1AUKA 1K7HA 3BDGA 1URBA 2W8DA 2IUCB 1KHLA 2VQRA 4UORA 4NWJA 4QAXA 2ANHA 2W5WA 1EW8A 1HJKA 3KD8A 2XR9A 2W5RA 4YR1A 4LR9A 5L0BA 1ZEBA 1FSUA 3T02A 1O98A 4UPKA 4GTZA 4CXSA 1KH4A 4GTWA 3WAXA 3WAWA 1ED9A 1N2KA 1KH5A 1SHQA
chains in the Genus database with same CATH superfamily
2GSOA 4UOPA 1EQJA 4UPIA 3NKRA 3TX0A 5KXAA 2W5SA 4LRAA 2QZUA 4LRFA 1EJJA 4GTYA 3UN3A 4CXUA 3NKMA 2G9YA 4B56A 1Y6VA 3SZYA 1ELZA 5EGHA 2D1GA 5DLVA 2GLQA 4LRCA 5EGEA 3BDFA 3MK0A 4KJGA 5L0EA 3DYCA 3M8ZA 3ED4A 5HRTA 3SZZA 3Q3QA 3T01A 3M8WA 3NVLA 1E1ZP 1AJAA 1ED8A 4LRBA 3WBHA 1E2SP 2IFYA 3NKOA 1ZEFA 1ALKA 3BDGB 3T00A 3IGZB 1B8JA 4LR7A 1ALHA 3UNYA 4TN0A 1KHKA 1Y7AA 3NKNA 4GTXA 3LXQA 4CYSA 5DLTA 3IGYB 3UN2A 1ELXA 1O99A 4FDJA 2X98A 3MK1A 1HDHA 4ZG7A 5GRRA 2W5VA 1AJBA 1SHNA 4LRDA 2GSUA 3DPCA 4MY4A 5K4PA 5LRMA 1E33P 4KJDA 4LQYA 1ANIA 3B5QA 5C66A 5DLWA 1ALJA 1ANJA 2W5QA 2W8SA 4KM4A 3UN5A 2RH6A 2IUCA 4KAVA 4LR2A 3TWZA 3CMRA 3WAVA 4UOOA 1KHNA 1N2LA 2GSNA 5LQQA 4N7TA 4FDIA 5IJSA 2XRGA 4NWXA 1KH9A 4ZG9A 4KAYA 2GA3A 4MIVA 1EW2A 3IDDA 4MHXA 4ZGAA 1ALIA 5LIAA 2W5XA 1P49A 3E2DA 3TG0A 4UPLA 4LR8A 1URAA 4ZG6A 3BDHA 1ELYA 1AJCA 1HQAA 4CYRA 5IJQA 5INHA 3NKPA 3MK2A 3OT9A 3M7VA 3A52A 4UPHA 5GOVA 3M8YA 5LRNA 5L0KA 1EI6A 4LREA 5AJ9A 5TJ3A 2ZKTA 2W5TA 1KHJA 3UO0A 1E3CP 1AJDA 1ZEDA 1KH7A 1EW9A 3WAYA 4CXKA 3NKQA 1AUKA 1K7HA 3BDGA 1URBA 2W8DA 2IUCB 1KHLA 2VQRA 4UORA 4NWJA 4QAXA 2ANHA 2W5WA 1EW8A 1HJKA 3KD8A 2XR9A 2W5RA 4YR1A 4LR9A 5L0BA 1ZEBA 1FSUA 3T02A 1O98A 4UPKA 4GTZA 4CXSA 1KH4A 4GTWA 3WAXA 3WAWA 1ED9A 1N2KA 1KH5A 1SHQA
chains in the Genus database with same CATH topology
2GSOA 4UOPA 1EQJA 4UPIA 3NKRA 3TX0A 5KXAA 2W5SA 4LRAA 2QZUA 4LRFA 1EJJA 4GTYA 3UN3A 4CXUA 3NKMA 2G9YA 4B56A 1Y6VA 3SZYA 1ELZA 5EGHA 2D1GA 5DLVA 2GLQA 4LRCA 5EGEA 3BDFA 3MK0A 4KJGA 5L0EA 3DYCA 3M8ZA 3ED4A 5HRTA 3SZZA 3Q3QA 3T01A 3M8WA 3NVLA 1E1ZP 1AJAA 1ED8A 4LRBA 3WBHA 1E2SP 2IFYA 3NKOA 1ZEFA 1ALKA 3BDGB 3T00A 3IGZB 1B8JA 4LR7A 1ALHA 3UNYA 4TN0A 1KHKA 1Y7AA 3NKNA 4GTXA 3LXQA 4CYSA 5DLTA 3IGYB 3UN2A 1ELXA 1O99A 4FDJA 2X98A 3MK1A 1HDHA 4ZG7A 5GRRA 2W5VA 1AJBA 1SHNA 4LRDA 2GSUA 3DPCA 4MY4A 5K4PA 5LRMA 1E33P 4KJDA 4LQYA 1ANIA 3B5QA 5C66A 5DLWA 1ALJA 1ANJA 2W5QA 2W8SA 4KM4A 3UN5A 2RH6A 2IUCA 4KAVA 4LR2A 3TWZA 3CMRA 3WAVA 4UOOA 1KHNA 1N2LA 2GSNA 5LQQA 4N7TA 4FDIA 5IJSA 2XRGA 4NWXA 1KH9A 4ZG9A 4KAYA 2GA3A 4MIVA 1EW2A 3IDDA 4MHXA 4ZGAA 1ALIA 5LIAA 2W5XA 1P49A 3E2DA 3TG0A 4UPLA 4LR8A 1URAA 4ZG6A 3BDHA 1ELYA 1AJCA 1HQAA 4CYRA 5IJQA 5INHA 3NKPA 3MK2A 3OT9A 3M7VA 3A52A 4UPHA 5GOVA 3M8YA 5LRNA 5L0KA 1EI6A 4LREA 5AJ9A 5TJ3A 2ZKTA 2W5TA 1KHJA 3UO0A 1E3CP 1AJDA 1ZEDA 1KH7A 1EW9A 3WAYA 4CXKA 3NKQA 1AUKA 1K7HA 3BDGA 1URBA 2W8DA 2IUCB 1KHLA 2VQRA 4UORA 4NWJA 4QAXA 2ANHA 2W5WA 1EW8A 1HJKA 3KD8A 2XR9A 2W5RA 4YR1A 4LR9A 5L0BA 1ZEBA 1FSUA 3T02A 1O98A 4UPKA 4GTZA 4CXSA 1KH4A 4GTWA 3WAXA 3WAWA 1ED9A 1N2KA 1KH5A 1SHQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GSO A;  4UOP A;  1EQJ A;  4UPI A;  3NKR A;  3TX0 A;  5KXA A;  2W5S A;  4LRA A;  2QZU A;  4LRF A;  1EJJ A;  4GTY A;  3UN3 A;  4CXU A;  3NKM A;  2G9Y A;  4B56 A;  1Y6V A;  3SZY A;  1ELZ A;  5EGH A;  2D1G A;  5DLV A;  2GLQ A;  4LRC A;  5EGE A;  3BDF A;  3MK0 A;  4KJG A;  5L0E A;  3DYC A;  3M8Z A;  3ED4 A;  5HRT A;  3SZZ A;  3Q3Q A;  3T01 A;  3M8W A;  3NVL A;  1E1Z P;  1AJA A;  1ED8 A;  4LRB A;  3WBH A;  1E2S P;  2IFY A;  3NKO A;  1ZEF A;  1ALK A;  3BDG B;  3T00 A;  3IGZ B;  1B8J A;  4LR7 A;  1ALH A;  3UNY A;  4TN0 A;  1KHK A;  1Y7A A;  3NKN A;  4GTX A;  3LXQ A;  4CYS A;  5DLT A;  3IGY B;  3UN2 A;  1ELX A;  1O99 A;  4FDJ A;  2X98 A;  3MK1 A;  1HDH A;  4ZG7 A;  5GRR A;  2W5V A;  1AJB A;  1SHN A;  4LRD A;  2GSU A;  3DPC A;  4MY4 A;  5K4P A;  5LRM A;  1E33 P;  4KJD A;  4LQY A;  1ANI A;  3B5Q A;  5C66 A;  5DLW A;  1ALJ A;  1ANJ A;  2W5Q A;  2W8S A;  4KM4 A;  3UN5 A;  2RH6 A;  2IUC A;  4KAV A;  4LR2 A;  3TWZ A;  3CMR A;  3WAV A;  4UOO A;  1KHN A;  1N2L A;  2GSN A;  5LQQ A;  4N7T A;  4FDI A;  5IJS A;  2XRG A;  4NWX A;  1KH9 A;  4ZG9 A;  4KAY A;  2GA3 A;  4MIV A;  1EW2 A;  3IDD A;  4MHX A;  4ZGA A;  1ALI A;  5LIA A;  2W5X A;  1P49 A;  3E2D A;  3TG0 A;  4UPL A;  4LR8 A;  1URA A;  4ZG6 A;  3BDH A;  1ELY A;  1AJC A;  1HQA A;  4CYR A;  5IJQ A;  5INH A;  3NKP A;  3MK2 A;  3OT9 A;  3M7V A;  3A52 A;  4UPH A;  5GOV A;  3M8Y A;  5LRN A;  5L0K A;  1EI6 A;  4LRE A;  5AJ9 A;  5TJ3 A;  2ZKT A;  2W5T A;  1KHJ A;  3UO0 A;  1E3C P;  1AJD A;  1ZED A;  1KH7 A;  1EW9 A;  3WAY A;  4CXK A;  3NKQ A;  1AUK A;  1K7H A;  3BDG A;  1URB A;  2W8D A;  2IUC B;  1KHL A;  2VQR A;  4UOR A;  4NWJ A;  4QAX A;  2ANH A;  2W5W A;  1EW8 A;  1HJK A;  3KD8 A;  2XR9 A;  2W5R A;  4YR1 A;  4LR9 A;  5L0B A;  1ZEB A;  1FSU A;  3T02 A;  1O98 A;  4UPK A;  4GTZ A;  4CXS A;  1KH4 A;  4GTW A;  3WAX A;  3WAW A;  1ED9 A;  1N2K A;  1KH5 A;  1SHQ A; 
#chains in the Genus database with same CATH topology
 2GSO A;  4UOP A;  1EQJ A;  4UPI A;  3NKR A;  3TX0 A;  5KXA A;  2W5S A;  4LRA A;  2QZU A;  4LRF A;  1EJJ A;  4GTY A;  3UN3 A;  4CXU A;  3NKM A;  2G9Y A;  4B56 A;  1Y6V A;  3SZY A;  1ELZ A;  5EGH A;  2D1G A;  5DLV A;  2GLQ A;  4LRC A;  5EGE A;  3BDF A;  3MK0 A;  4KJG A;  5L0E A;  3DYC A;  3M8Z A;  3ED4 A;  5HRT A;  3SZZ A;  3Q3Q A;  3T01 A;  3M8W A;  3NVL A;  1E1Z P;  1AJA A;  1ED8 A;  4LRB A;  3WBH A;  1E2S P;  2IFY A;  3NKO A;  1ZEF A;  1ALK A;  3BDG B;  3T00 A;  3IGZ B;  1B8J A;  4LR7 A;  1ALH A;  3UNY A;  4TN0 A;  1KHK A;  1Y7A A;  3NKN A;  4GTX A;  3LXQ A;  4CYS A;  5DLT A;  3IGY B;  3UN2 A;  1ELX A;  1O99 A;  4FDJ A;  2X98 A;  3MK1 A;  1HDH A;  4ZG7 A;  5GRR A;  2W5V A;  1AJB A;  1SHN A;  4LRD A;  2GSU A;  3DPC A;  4MY4 A;  5K4P A;  5LRM A;  1E33 P;  4KJD A;  4LQY A;  1ANI A;  3B5Q A;  5C66 A;  5DLW A;  1ALJ A;  1ANJ A;  2W5Q A;  2W8S A;  4KM4 A;  3UN5 A;  2RH6 A;  2IUC A;  4KAV A;  4LR2 A;  3TWZ A;  3CMR A;  3WAV A;  4UOO A;  1KHN A;  1N2L A;  2GSN A;  5LQQ A;  4N7T A;  4FDI A;  5IJS A;  2XRG A;  4NWX A;  1KH9 A;  4ZG9 A;  4KAY A;  2GA3 A;  4MIV A;  1EW2 A;  3IDD A;  4MHX A;  4ZGA A;  1ALI A;  5LIA A;  2W5X A;  1P49 A;  3E2D A;  3TG0 A;  4UPL A;  4LR8 A;  1URA A;  4ZG6 A;  3BDH A;  1ELY A;  1AJC A;  1HQA A;  4CYR A;  5IJQ A;  5INH A;  3NKP A;  3MK2 A;  3OT9 A;  3M7V A;  3A52 A;  4UPH A;  5GOV A;  3M8Y A;  5LRN A;  5L0K A;  1EI6 A;  4LRE A;  5AJ9 A;  5TJ3 A;  2ZKT A;  2W5T A;  1KHJ A;  3UO0 A;  1E3C P;  1AJD A;  1ZED A;  1KH7 A;  1EW9 A;  3WAY A;  4CXK A;  3NKQ A;  1AUK A;  1K7H A;  3BDG A;  1URB A;  2W8D A;  2IUC B;  1KHL A;  2VQR A;  4UOR A;  4NWJ A;  4QAX A;  2ANH A;  2W5W A;  1EW8 A;  1HJK A;  3KD8 A;  2XR9 A;  2W5R A;  4YR1 A;  4LR9 A;  5L0B A;  1ZEB A;  1FSU A;  3T02 A;  1O98 A;  4UPK A;  4GTZ A;  4CXS A;  1KH4 A;  4GTW A;  3WAX A;  3WAW A;  1ED9 A;  1N2K A;  1KH5 A;  1SHQ A; 
#chains in the Genus database with same CATH homology
 2GSO A;  4UOP A;  1EQJ A;  4UPI A;  3NKR A;  3TX0 A;  5KXA A;  2W5S A;  4LRA A;  2QZU A;  4LRF A;  1EJJ A;  4GTY A;  3UN3 A;  4CXU A;  3NKM A;  2G9Y A;  4B56 A;  1Y6V A;  3SZY A;  1ELZ A;  5EGH A;  2D1G A;  5DLV A;  2GLQ A;  4LRC A;  5EGE A;  3BDF A;  3MK0 A;  4KJG A;  5L0E A;  3DYC A;  3M8Z A;  3ED4 A;  5HRT A;  3SZZ A;  3Q3Q A;  3T01 A;  3M8W A;  3NVL A;  1E1Z P;  1AJA A;  1ED8 A;  4LRB A;  3WBH A;  1E2S P;  2IFY A;  3NKO A;  1ZEF A;  1ALK A;  3BDG B;  3T00 A;  3IGZ B;  1B8J A;  4LR7 A;  1ALH A;  3UNY A;  4TN0 A;  1KHK A;  1Y7A A;  3NKN A;  4GTX A;  3LXQ A;  4CYS A;  5DLT A;  3IGY B;  3UN2 A;  1ELX A;  1O99 A;  4FDJ A;  2X98 A;  3MK1 A;  1HDH A;  4ZG7 A;  5GRR A;  2W5V A;  1AJB A;  1SHN A;  4LRD A;  2GSU A;  3DPC A;  4MY4 A;  5K4P A;  5LRM A;  1E33 P;  4KJD A;  4LQY A;  1ANI A;  3B5Q A;  5C66 A;  5DLW A;  1ALJ A;  1ANJ A;  2W5Q A;  2W8S A;  4KM4 A;  3UN5 A;  2RH6 A;  2IUC A;  4KAV A;  4LR2 A;  3TWZ A;  3CMR A;  3WAV A;  4UOO A;  1KHN A;  1N2L A;  2GSN A;  5LQQ A;  4N7T A;  4FDI A;  5IJS A;  2XRG A;  4NWX A;  1KH9 A;  4ZG9 A;  4KAY A;  2GA3 A;  4MIV A;  1EW2 A;  3IDD A;  4MHX A;  4ZGA A;  1ALI A;  5LIA A;  2W5X A;  1P49 A;  3E2D A;  3TG0 A;  4UPL A;  4LR8 A;  1URA A;  4ZG6 A;  3BDH A;  1ELY A;  1AJC A;  1HQA A;  4CYR A;  5IJQ A;  5INH A;  3NKP A;  3MK2 A;  3OT9 A;  3M7V A;  3A52 A;  4UPH A;  5GOV A;  3M8Y A;  5LRN A;  5L0K A;  1EI6 A;  4LRE A;  5AJ9 A;  5TJ3 A;  2ZKT A;  2W5T A;  1KHJ A;  3UO0 A;  1E3C P;  1AJD A;  1ZED A;  1KH7 A;  1EW9 A;  3WAY A;  4CXK A;  3NKQ A;  1AUK A;  1K7H A;  3BDG A;  1URB A;  2W8D A;  2IUC B;  1KHL A;  2VQR A;  4UOR A;  4NWJ A;  4QAX A;  2ANH A;  2W5W A;  1EW8 A;  1HJK A;  3KD8 A;  2XR9 A;  2W5R A;  4YR1 A;  4LR9 A;  5L0B A;  1ZEB A;  1FSU A;  3T02 A;  1O98 A;  4UPK A;  4GTZ A;  4CXS A;  1KH4 A;  4GTW A;  3WAX A;  3WAW A;  1ED9 A;  1N2K A;  1KH5 A;  1SHQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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