3DYCA

Structure of e322y alkaline phosphatase in complex with inorganic phosphate
Total Genus 156
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
156
Knots found
sequence length
446
structure length
446
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVYGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Alkaline phosphatase
total genus 156
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dycA00
2IFYA 2GSUA 1ALIA 4CXSA 5GRRA 3B5QA 1K7HA 4KJGA 4CYSA 2ANHA 3SZZA 2IUCB 3NKOA 3NKMA 5KXAA 5LQQA 4GTZA 3TG0A 4KAVA 2GSNA 3TX0A 2GLQA 1FSUA 2W5RA 4UOOA 5DLVA 4NWJA 1ELYA 1AJBA 4MHXA 1ED8A 2QZUA 5L0KA 1URAA 1ALJA 5EGEA 1ANJA 3DPCA 1EQJA 1ZEFA 1N2KA 1EI6A 3M8WA 3SZYA 4CXUA 1P49A 4LRFA 3UNYA 1E33P 2W5VA 2W5XA 4UORA 2G9YA 3WAWA 2W5TA 2D1GA 5IJQA 3WAVA 4LREA 1HQAA 5GOVA 3NKQA 1B8JA 1AUKA 4LQYA 3BDHA 3OT9A 1Y6VA 5EGHA 1ZEDA 1ELZA 1EW9A 1KHLA 2XRGA 4GTYA 1HDHA 3A52A 2X98A 3TWZA 3WAYA 3BDGB 5IJSA 2W5SA 3E2DA 1N2LA 4UPLA 3NKPA 1O98A 4NWXA 3NKNA 4LRDA 1ELXA 1E2SP 3T01A 3KD8A 2W5QA 3T00A 4LRBA 4UPHA 4B56A 3M8ZA 3LXQA 1ED9A 2W8DA 3NVLA 5LRMA 1EJJA 4LR8A 4ZG9A 2IUCA 3IGYB 1ALHA 1KHKA 4LR2A 3T02A 3IDDA 1Y7AA 1SHNA 3ED4A 5K4PA 5TJ3A 4GTWA 4ZG7A 3UN2A 1EW2A 1ALKA 4UPIA 5C66A 4YR1A 2VQRA 2GA3A 3M8YA 4ZG6A 1ANIA 4LR7A 5AJ9A 5DLWA 3IGZB 1KHJA 1E1ZP 2ZKTA 3NKRA 5LIAA 1KHNA 2RH6A 5L0BA 1AJDA 4FDJA 4KAYA 3UO0A 1AJAA 3UN5A 4CYRA 3CMRA 1EW8A 1SHQA 3Q3QA 3BDFA 3M7VA 4QAXA 3MK2A 4GTXA 1O99A 1HJKA 4LR9A 4N7TA 3MK0A 4MY4A 5INHA 4TN0A 4LRCA 1ZEBA 3DYCA 5HRTA 4CXKA 1KH5A 4KM4A 5DLTA 2W5WA 1KH9A 3WAXA 4ZGAA 1E3CP 1KH4A 4MIVA 4UPKA 2GSOA 1KH7A 3BDGA 3MK1A 4KJDA 4UOPA 2XR9A 5LRNA 5L0EA 4FDIA 4LRAA 1AJCA 1URBA 3WBHA 3UN3A 2W8SA
chains in the Genus database with same CATH superfamily
2IFYA 2GSUA 1ALIA 4CXSA 5GRRA 3B5QA 1K7HA 4KJGA 4CYSA 2ANHA 3SZZA 2IUCB 3NKOA 3NKMA 5KXAA 5LQQA 4GTZA 3TG0A 4KAVA 2GSNA 3TX0A 2GLQA 1FSUA 2W5RA 4UOOA 5DLVA 4NWJA 1ELYA 1AJBA 4MHXA 1ED8A 2QZUA 5L0KA 1URAA 1ALJA 5EGEA 1ANJA 3DPCA 1EQJA 1ZEFA 1N2KA 1EI6A 3M8WA 3SZYA 4CXUA 1P49A 4LRFA 3UNYA 1E33P 2W5VA 2W5XA 4UORA 2G9YA 3WAWA 2W5TA 2D1GA 5IJQA 3WAVA 4LREA 1HQAA 5GOVA 3NKQA 1B8JA 1AUKA 4LQYA 3BDHA 3OT9A 1Y6VA 5EGHA 1ZEDA 1ELZA 1EW9A 1KHLA 2XRGA 4GTYA 1HDHA 3A52A 2X98A 3TWZA 3WAYA 3BDGB 5IJSA 2W5SA 3E2DA 1N2LA 4UPLA 3NKPA 1O98A 4NWXA 3NKNA 4LRDA 1ELXA 1E2SP 3T01A 3KD8A 2W5QA 3T00A 4LRBA 4UPHA 4B56A 3M8ZA 3LXQA 1ED9A 2W8DA 3NVLA 5LRMA 1EJJA 4LR8A 4ZG9A 2IUCA 3IGYB 1ALHA 1KHKA 4LR2A 3T02A 3IDDA 1Y7AA 1SHNA 3ED4A 5K4PA 5TJ3A 4GTWA 4ZG7A 3UN2A 1EW2A 1ALKA 4UPIA 5C66A 4YR1A 2VQRA 2GA3A 3M8YA 4ZG6A 1ANIA 4LR7A 5AJ9A 5DLWA 3IGZB 1KHJA 1E1ZP 2ZKTA 3NKRA 5LIAA 1KHNA 2RH6A 5L0BA 1AJDA 4FDJA 4KAYA 3UO0A 1AJAA 3UN5A 4CYRA 3CMRA 1EW8A 1SHQA 3Q3QA 3BDFA 3M7VA 4QAXA 3MK2A 4GTXA 1O99A 1HJKA 4LR9A 4N7TA 3MK0A 4MY4A 5INHA 4TN0A 4LRCA 1ZEBA 3DYCA 5HRTA 4CXKA 1KH5A 4KM4A 5DLTA 2W5WA 1KH9A 3WAXA 4ZGAA 1E3CP 1KH4A 4MIVA 4UPKA 2GSOA 1KH7A 3BDGA 3MK1A 4KJDA 4UOPA 2XR9A 5LRNA 5L0EA 4FDIA 4LRAA 1AJCA 1URBA 3WBHA 3UN3A 2W8SA
chains in the Genus database with same CATH topology
2IFYA 2GSUA 1ALIA 4CXSA 5GRRA 3B5QA 1K7HA 4KJGA 4CYSA 2ANHA 3SZZA 2IUCB 3NKOA 3NKMA 5KXAA 5LQQA 4GTZA 3TG0A 4KAVA 2GSNA 3TX0A 2GLQA 1FSUA 2W5RA 4UOOA 5DLVA 4NWJA 1ELYA 1AJBA 4MHXA 1ED8A 2QZUA 5L0KA 1URAA 1ALJA 5EGEA 1ANJA 3DPCA 1EQJA 1ZEFA 1N2KA 1EI6A 3M8WA 3SZYA 4CXUA 1P49A 4LRFA 3UNYA 1E33P 2W5VA 2W5XA 4UORA 2G9YA 3WAWA 2W5TA 2D1GA 5IJQA 3WAVA 4LREA 1HQAA 5GOVA 3NKQA 1B8JA 1AUKA 4LQYA 3BDHA 3OT9A 1Y6VA 5EGHA 1ZEDA 1ELZA 1EW9A 1KHLA 2XRGA 4GTYA 1HDHA 3A52A 2X98A 3TWZA 3WAYA 3BDGB 5IJSA 2W5SA 3E2DA 1N2LA 4UPLA 3NKPA 1O98A 4NWXA 3NKNA 4LRDA 1ELXA 1E2SP 3T01A 3KD8A 2W5QA 3T00A 4LRBA 4UPHA 4B56A 3M8ZA 3LXQA 1ED9A 2W8DA 3NVLA 5LRMA 1EJJA 4LR8A 4ZG9A 2IUCA 3IGYB 1ALHA 1KHKA 4LR2A 3T02A 3IDDA 1Y7AA 1SHNA 3ED4A 5K4PA 5TJ3A 4GTWA 4ZG7A 3UN2A 1EW2A 1ALKA 4UPIA 5C66A 4YR1A 2VQRA 2GA3A 3M8YA 4ZG6A 1ANIA 4LR7A 5AJ9A 5DLWA 3IGZB 1KHJA 1E1ZP 2ZKTA 3NKRA 5LIAA 1KHNA 2RH6A 5L0BA 1AJDA 4FDJA 4KAYA 3UO0A 1AJAA 3UN5A 4CYRA 3CMRA 1EW8A 1SHQA 3Q3QA 3BDFA 3M7VA 4QAXA 3MK2A 4GTXA 1O99A 1HJKA 4LR9A 4N7TA 3MK0A 4MY4A 5INHA 4TN0A 4LRCA 1ZEBA 3DYCA 5HRTA 4CXKA 1KH5A 4KM4A 5DLTA 2W5WA 1KH9A 3WAXA 4ZGAA 1E3CP 1KH4A 4MIVA 4UPKA 2GSOA 1KH7A 3BDGA 3MK1A 4KJDA 4UOPA 2XR9A 5LRNA 5L0EA 4FDIA 4LRAA 1AJCA 1URBA 3WBHA 3UN3A 2W8SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IFY A;  2GSU A;  1ALI A;  4CXS A;  5GRR A;  3B5Q A;  1K7H A;  4KJG A;  4CYS A;  2ANH A;  3SZZ A;  2IUC B;  3NKO A;  3NKM A;  5KXA A;  5LQQ A;  4GTZ A;  3TG0 A;  4KAV A;  2GSN A;  3TX0 A;  2GLQ A;  1FSU A;  2W5R A;  4UOO A;  5DLV A;  4NWJ A;  1ELY A;  1AJB A;  4MHX A;  1ED8 A;  2QZU A;  5L0K A;  1URA A;  1ALJ A;  5EGE A;  1ANJ A;  3DPC A;  1EQJ A;  1ZEF A;  1N2K A;  1EI6 A;  3M8W A;  3SZY A;  4CXU A;  1P49 A;  4LRF A;  3UNY A;  1E33 P;  2W5V A;  2W5X A;  4UOR A;  2G9Y A;  3WAW A;  2W5T A;  2D1G A;  5IJQ A;  3WAV A;  4LRE A;  1HQA A;  5GOV A;  3NKQ A;  1B8J A;  1AUK A;  4LQY A;  3BDH A;  3OT9 A;  1Y6V A;  5EGH A;  1ZED A;  1ELZ A;  1EW9 A;  1KHL A;  2XRG A;  4GTY A;  1HDH A;  3A52 A;  2X98 A;  3TWZ A;  3WAY A;  3BDG B;  5IJS A;  2W5S A;  3E2D A;  1N2L A;  4UPL A;  3NKP A;  1O98 A;  4NWX A;  3NKN A;  4LRD A;  1ELX A;  1E2S P;  3T01 A;  3KD8 A;  2W5Q A;  3T00 A;  4LRB A;  4UPH A;  4B56 A;  3M8Z A;  3LXQ A;  1ED9 A;  2W8D A;  3NVL A;  5LRM A;  1EJJ A;  4LR8 A;  4ZG9 A;  2IUC A;  3IGY B;  1ALH A;  1KHK A;  4LR2 A;  3T02 A;  3IDD A;  1Y7A A;  1SHN A;  3ED4 A;  5K4P A;  5TJ3 A;  4GTW A;  4ZG7 A;  3UN2 A;  1EW2 A;  1ALK A;  4UPI A;  5C66 A;  4YR1 A;  2VQR A;  2GA3 A;  3M8Y A;  4ZG6 A;  1ANI A;  4LR7 A;  5AJ9 A;  5DLW A;  3IGZ B;  1KHJ A;  1E1Z P;  2ZKT A;  3NKR A;  5LIA A;  1KHN A;  2RH6 A;  5L0B A;  1AJD A;  4FDJ A;  4KAY A;  3UO0 A;  1AJA A;  3UN5 A;  4CYR A;  3CMR A;  1EW8 A;  1SHQ A;  3Q3Q A;  3BDF A;  3M7V A;  4QAX A;  3MK2 A;  4GTX A;  1O99 A;  1HJK A;  4LR9 A;  4N7T A;  3MK0 A;  4MY4 A;  5INH A;  4TN0 A;  4LRC A;  1ZEB A;  3DYC A;  5HRT A;  4CXK A;  1KH5 A;  4KM4 A;  5DLT A;  2W5W A;  1KH9 A;  3WAX A;  4ZGA A;  1E3C P;  1KH4 A;  4MIV A;  4UPK A;  2GSO A;  1KH7 A;  3BDG A;  3MK1 A;  4KJD A;  4UOP A;  2XR9 A;  5LRN A;  5L0E A;  4FDI A;  4LRA A;  1AJC A;  1URB A;  3WBH A;  3UN3 A;  2W8S A; 
#chains in the Genus database with same CATH topology
 2IFY A;  2GSU A;  1ALI A;  4CXS A;  5GRR A;  3B5Q A;  1K7H A;  4KJG A;  4CYS A;  2ANH A;  3SZZ A;  2IUC B;  3NKO A;  3NKM A;  5KXA A;  5LQQ A;  4GTZ A;  3TG0 A;  4KAV A;  2GSN A;  3TX0 A;  2GLQ A;  1FSU A;  2W5R A;  4UOO A;  5DLV A;  4NWJ A;  1ELY A;  1AJB A;  4MHX A;  1ED8 A;  2QZU A;  5L0K A;  1URA A;  1ALJ A;  5EGE A;  1ANJ A;  3DPC A;  1EQJ A;  1ZEF A;  1N2K A;  1EI6 A;  3M8W A;  3SZY A;  4CXU A;  1P49 A;  4LRF A;  3UNY A;  1E33 P;  2W5V A;  2W5X A;  4UOR A;  2G9Y A;  3WAW A;  2W5T A;  2D1G A;  5IJQ A;  3WAV A;  4LRE A;  1HQA A;  5GOV A;  3NKQ A;  1B8J A;  1AUK A;  4LQY A;  3BDH A;  3OT9 A;  1Y6V A;  5EGH A;  1ZED A;  1ELZ A;  1EW9 A;  1KHL A;  2XRG A;  4GTY A;  1HDH A;  3A52 A;  2X98 A;  3TWZ A;  3WAY A;  3BDG B;  5IJS A;  2W5S A;  3E2D A;  1N2L A;  4UPL A;  3NKP A;  1O98 A;  4NWX A;  3NKN A;  4LRD A;  1ELX A;  1E2S P;  3T01 A;  3KD8 A;  2W5Q A;  3T00 A;  4LRB A;  4UPH A;  4B56 A;  3M8Z A;  3LXQ A;  1ED9 A;  2W8D A;  3NVL A;  5LRM A;  1EJJ A;  4LR8 A;  4ZG9 A;  2IUC A;  3IGY B;  1ALH A;  1KHK A;  4LR2 A;  3T02 A;  3IDD A;  1Y7A A;  1SHN A;  3ED4 A;  5K4P A;  5TJ3 A;  4GTW A;  4ZG7 A;  3UN2 A;  1EW2 A;  1ALK A;  4UPI A;  5C66 A;  4YR1 A;  2VQR A;  2GA3 A;  3M8Y A;  4ZG6 A;  1ANI A;  4LR7 A;  5AJ9 A;  5DLW A;  3IGZ B;  1KHJ A;  1E1Z P;  2ZKT A;  3NKR A;  5LIA A;  1KHN A;  2RH6 A;  5L0B A;  1AJD A;  4FDJ A;  4KAY A;  3UO0 A;  1AJA A;  3UN5 A;  4CYR A;  3CMR A;  1EW8 A;  1SHQ A;  3Q3Q A;  3BDF A;  3M7V A;  4QAX A;  3MK2 A;  4GTX A;  1O99 A;  1HJK A;  4LR9 A;  4N7T A;  3MK0 A;  4MY4 A;  5INH A;  4TN0 A;  4LRC A;  1ZEB A;  3DYC A;  5HRT A;  4CXK A;  1KH5 A;  4KM4 A;  5DLT A;  2W5W A;  1KH9 A;  3WAX A;  4ZGA A;  1E3C P;  1KH4 A;  4MIV A;  4UPK A;  2GSO A;  1KH7 A;  3BDG A;  3MK1 A;  4KJD A;  4UOP A;  2XR9 A;  5LRN A;  5L0E A;  4FDI A;  4LRA A;  1AJC A;  1URB A;  3WBH A;  3UN3 A;  2W8S A; 
#chains in the Genus database with same CATH homology
 2IFY A;  2GSU A;  1ALI A;  4CXS A;  5GRR A;  3B5Q A;  1K7H A;  4KJG A;  4CYS A;  2ANH A;  3SZZ A;  2IUC B;  3NKO A;  3NKM A;  5KXA A;  5LQQ A;  4GTZ A;  3TG0 A;  4KAV A;  2GSN A;  3TX0 A;  2GLQ A;  1FSU A;  2W5R A;  4UOO A;  5DLV A;  4NWJ A;  1ELY A;  1AJB A;  4MHX A;  1ED8 A;  2QZU A;  5L0K A;  1URA A;  1ALJ A;  5EGE A;  1ANJ A;  3DPC A;  1EQJ A;  1ZEF A;  1N2K A;  1EI6 A;  3M8W A;  3SZY A;  4CXU A;  1P49 A;  4LRF A;  3UNY A;  1E33 P;  2W5V A;  2W5X A;  4UOR A;  2G9Y A;  3WAW A;  2W5T A;  2D1G A;  5IJQ A;  3WAV A;  4LRE A;  1HQA A;  5GOV A;  3NKQ A;  1B8J A;  1AUK A;  4LQY A;  3BDH A;  3OT9 A;  1Y6V A;  5EGH A;  1ZED A;  1ELZ A;  1EW9 A;  1KHL A;  2XRG A;  4GTY A;  1HDH A;  3A52 A;  2X98 A;  3TWZ A;  3WAY A;  3BDG B;  5IJS A;  2W5S A;  3E2D A;  1N2L A;  4UPL A;  3NKP A;  1O98 A;  4NWX A;  3NKN A;  4LRD A;  1ELX A;  1E2S P;  3T01 A;  3KD8 A;  2W5Q A;  3T00 A;  4LRB A;  4UPH A;  4B56 A;  3M8Z A;  3LXQ A;  1ED9 A;  2W8D A;  3NVL A;  5LRM A;  1EJJ A;  4LR8 A;  4ZG9 A;  2IUC A;  3IGY B;  1ALH A;  1KHK A;  4LR2 A;  3T02 A;  3IDD A;  1Y7A A;  1SHN A;  3ED4 A;  5K4P A;  5TJ3 A;  4GTW A;  4ZG7 A;  3UN2 A;  1EW2 A;  1ALK A;  4UPI A;  5C66 A;  4YR1 A;  2VQR A;  2GA3 A;  3M8Y A;  4ZG6 A;  1ANI A;  4LR7 A;  5AJ9 A;  5DLW A;  3IGZ B;  1KHJ A;  1E1Z P;  2ZKT A;  3NKR A;  5LIA A;  1KHN A;  2RH6 A;  5L0B A;  1AJD A;  4FDJ A;  4KAY A;  3UO0 A;  1AJA A;  3UN5 A;  4CYR A;  3CMR A;  1EW8 A;  1SHQ A;  3Q3Q A;  3BDF A;  3M7V A;  4QAX A;  3MK2 A;  4GTX A;  1O99 A;  1HJK A;  4LR9 A;  4N7T A;  3MK0 A;  4MY4 A;  5INH A;  4TN0 A;  4LRC A;  1ZEB A;  3DYC A;  5HRT A;  4CXK A;  1KH5 A;  4KM4 A;  5DLT A;  2W5W A;  1KH9 A;  3WAX A;  4ZGA A;  1E3C P;  1KH4 A;  4MIV A;  4UPK A;  2GSO A;  1KH7 A;  3BDG A;  3MK1 A;  4KJD A;  4UOP A;  2XR9 A;  5LRN A;  5L0E A;  4FDI A;  4LRA A;  1AJC A;  1URB A;  3WBH A;  3UN3 A;  2W8S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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