3KD8A

Cofactor-independent phosphoglycerate mutase from thermoplasma acidophilum dsm 1728
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
Knots found
sequence length
396
structure length
367
Chain Sequence
MKSIILIVLDGLGDRPGSDLQNRTPLQAAFRPNLNWLASHGINGIMHPISPDTSHMSLLGYDPKVYYPGRGPFEALGLGMDIRPGDLAFRANFATNRDGVIVDRRAGRENKGNEELADAISLDMGEYSFRVKSGVEHRAALVVSGPDLSDMIGDSDPHREGLPPEKIRPTDPSGDRTAEVMNAYLEEARRILSDHRVNKERVKNGRLPGNELLVRSAGKVPAIPSFTEKNRMKGACVVGSPWLKGLCRLLRMDVFDVPGSNYRGKIEKAVDLTSSHDFVLVNIKATGNYPLKRDVIEDIDRAMEPLKSIGDHAVICVTGDGDPVPIVFYTDGVMNDGVHLFDELSSASGSLRITSYNVMDILMQLAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cofactor-Independent Phosphoglycerate mutase from Thermoplasma Acidophilum DSM 1728
rcsb
molecule tags Isomerase
source organism Thermoplasma acidophilum
molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
total genus 115
structure length 367
sequence length 396
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2009-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF10143 PhosphMutase 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3kd8A01
1ELZA 1KH4A 4NWJA 5K4PA 3MK0A 2W8SA 4GTYA 3UN2A 4GTXA 3M8ZA 4LRBA 3Q3QA 4LR2A 3WAXA 1FSUA 1URBA 2W5TA 3LXQA 4FDJA 4UOPA 3IDDA 4CXUA 5LQQA 1AJDA 1ZEDA 1E33P 1KH5A 2W5SA 3BDGA 3NKOA 3BDGB 1K7HA 5LRNA 4LRDA 4LQYA 3UN5A 3WAWA 1HQAA 3NKNA 4LR8A 2RH6A 3M8WA 3WAVA 3MK2A 2IFYA 3DYCA 1ZEFA 1ELYA 2QZUA 1EQJA 1KH9A 2IUCA 5IJQA 3MK1A 2IUCB 3NKRA 3TWZA 5IJSA 2ANHA 1O99A 4FDIA 4TN0A 5GRRA 4CYSA 3UNYA 2ZKTA 1E2SP 4B56A 4UPLA 1E3CP 3KD8A 4ZG9A 2W5XA 1O98A 1AJBA 2GSNA 4MIVA 3NKPA 3NKMA 5EGHA 1ANJA 4KJGA 4ZG6A 4UPKA 1URAA 3DPCA 2W5RA 2XR9A 1AUKA 4LRAA 3T01A 4UOOA 5DLVA 1KHLA 1HJKA 5AJ9A 3BDFA 4N7TA 1SHQA 4CXSA 5LIAA 2GSOA 3B5QA 4KAVA 4UPHA 1AJAA 5DLTA 1ED9A 1Y6VA 4CYRA 3M8YA 4KAYA 4LR7A 3IGYB 4NWXA 5EGEA 4GTZA 3SZZA 4QAXA 2GLQA 4UPIA 3T02A 3NVLA 3TG0A 3OT9A 4LRFA 2X98A 4MY4A 4LRCA 1EW2A 1Y7AA 5L0BA 1EW9A 2W5WA 2G9YA 1B8JA 5HRTA 5L0EA 2GSUA 1SHNA 4ZGAA 1KHNA 1ELXA 3WAYA 1ALIA 1EI6A 2XRGA 3IGZB 4KJDA 3A52A 3BDHA 1ZEBA 1KHKA 3CMRA 4UORA 3TX0A 1HDHA 3UN3A 1EJJA 1ED8A 4ZG7A 4GTWA 5C66A 1ALHA 1AJCA 5L0KA 1ANIA 5KXAA 2W5QA 1KHJA 3NKQA 5DLWA 1EW8A 1ALKA 3UO0A 4CXKA 3WBHA 5LRMA 5GOVA 4LREA 1N2KA 3M7VA 2W5VA 4LR9A 4KM4A 1N2LA 1ALJA 2VQRA 4YR1A 1P49A 2W8DA 1KH7A 5INHA 1E1ZP 5TJ3A 3T00A 3ED4A 3E2DA 2GA3A 4MHXA 3SZYA 2D1GA
chains in the Genus database with same CATH superfamily
1ELZA 1KH4A 4NWJA 5K4PA 3MK0A 2W8SA 4GTYA 3UN2A 4GTXA 3M8ZA 4LRBA 3Q3QA 4LR2A 3WAXA 1FSUA 1URBA 2W5TA 3LXQA 4FDJA 4UOPA 3IDDA 4CXUA 5LQQA 1AJDA 1ZEDA 1E33P 1KH5A 2W5SA 3BDGA 3NKOA 3BDGB 1K7HA 5LRNA 4LRDA 4LQYA 3UN5A 3WAWA 1HQAA 3NKNA 4LR8A 2RH6A 3M8WA 3WAVA 3MK2A 2IFYA 3DYCA 1ZEFA 1ELYA 2QZUA 1EQJA 1KH9A 2IUCA 5IJQA 3MK1A 2IUCB 3NKRA 3TWZA 5IJSA 2ANHA 1O99A 4FDIA 4TN0A 5GRRA 4CYSA 3UNYA 2ZKTA 1E2SP 4B56A 4UPLA 1E3CP 3KD8A 4ZG9A 2W5XA 1O98A 1AJBA 2GSNA 4MIVA 3NKPA 3NKMA 5EGHA 1ANJA 4KJGA 4ZG6A 4UPKA 1URAA 3DPCA 2W5RA 2XR9A 1AUKA 4LRAA 3T01A 4UOOA 5DLVA 1KHLA 1HJKA 5AJ9A 3BDFA 4N7TA 1SHQA 4CXSA 5LIAA 2GSOA 3B5QA 4KAVA 4UPHA 1AJAA 5DLTA 1ED9A 1Y6VA 4CYRA 3M8YA 4KAYA 4LR7A 3IGYB 4NWXA 5EGEA 4GTZA 3SZZA 4QAXA 2GLQA 4UPIA 3T02A 3NVLA 3TG0A 3OT9A 4LRFA 2X98A 4MY4A 4LRCA 1EW2A 1Y7AA 5L0BA 1EW9A 2W5WA 2G9YA 1B8JA 5HRTA 5L0EA 2GSUA 1SHNA 4ZGAA 1KHNA 1ELXA 3WAYA 1ALIA 1EI6A 2XRGA 3IGZB 4KJDA 3A52A 3BDHA 1ZEBA 1KHKA 3CMRA 4UORA 3TX0A 1HDHA 3UN3A 1EJJA 1ED8A 4ZG7A 4GTWA 5C66A 1ALHA 1AJCA 5L0KA 1ANIA 5KXAA 2W5QA 1KHJA 3NKQA 5DLWA 1EW8A 1ALKA 3UO0A 4CXKA 3WBHA 5LRMA 5GOVA 4LREA 1N2KA 3M7VA 2W5VA 4LR9A 4KM4A 1N2LA 1ALJA 2VQRA 4YR1A 1P49A 2W8DA 1KH7A 5INHA 1E1ZP 5TJ3A 3T00A 3ED4A 3E2DA 2GA3A 4MHXA 3SZYA 2D1GA
chains in the Genus database with same CATH topology
1ELZA 1KH4A 4NWJA 5K4PA 3MK0A 2W8SA 4GTYA 3UN2A 4GTXA 3M8ZA 4LRBA 3Q3QA 4LR2A 3WAXA 1FSUA 1URBA 2W5TA 3LXQA 4FDJA 4UOPA 3IDDA 4CXUA 5LQQA 1AJDA 1ZEDA 1E33P 1KH5A 2W5SA 3BDGA 3NKOA 3BDGB 1K7HA 5LRNA 4LRDA 4LQYA 3UN5A 3WAWA 1HQAA 3NKNA 4LR8A 2RH6A 3M8WA 3WAVA 3MK2A 2IFYA 3DYCA 1ZEFA 1ELYA 2QZUA 1EQJA 1KH9A 2IUCA 5IJQA 3MK1A 2IUCB 3NKRA 3TWZA 5IJSA 2ANHA 1O99A 4FDIA 4TN0A 5GRRA 4CYSA 3UNYA 2ZKTA 1E2SP 4B56A 4UPLA 1E3CP 3KD8A 4ZG9A 2W5XA 1O98A 1AJBA 2GSNA 4MIVA 3NKPA 3NKMA 5EGHA 1ANJA 4KJGA 4ZG6A 4UPKA 1URAA 3DPCA 2W5RA 2XR9A 1AUKA 4LRAA 3T01A 4UOOA 5DLVA 1KHLA 1HJKA 5AJ9A 3BDFA 4N7TA 1SHQA 4CXSA 5LIAA 2GSOA 3B5QA 4KAVA 4UPHA 1AJAA 5DLTA 1ED9A 1Y6VA 4CYRA 3M8YA 4KAYA 4LR7A 3IGYB 4NWXA 5EGEA 4GTZA 3SZZA 4QAXA 2GLQA 4UPIA 3T02A 3NVLA 3TG0A 3OT9A 4LRFA 2X98A 4MY4A 4LRCA 1EW2A 1Y7AA 5L0BA 1EW9A 2W5WA 2G9YA 1B8JA 5HRTA 5L0EA 2GSUA 1SHNA 4ZGAA 1KHNA 1ELXA 3WAYA 1ALIA 1EI6A 2XRGA 3IGZB 4KJDA 3A52A 3BDHA 1ZEBA 1KHKA 3CMRA 4UORA 3TX0A 1HDHA 3UN3A 1EJJA 1ED8A 4ZG7A 4GTWA 5C66A 1ALHA 1AJCA 5L0KA 1ANIA 5KXAA 2W5QA 1KHJA 3NKQA 5DLWA 1EW8A 1ALKA 3UO0A 4CXKA 3WBHA 5LRMA 5GOVA 4LREA 1N2KA 3M7VA 2W5VA 4LR9A 4KM4A 1N2LA 1ALJA 2VQRA 4YR1A 1P49A 2W8DA 1KH7A 5INHA 1E1ZP 5TJ3A 3T00A 3ED4A 3E2DA 2GA3A 4MHXA 3SZYA 2D1GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ELZ A;  1KH4 A;  4NWJ A;  5K4P A;  3MK0 A;  2W8S A;  4GTY A;  3UN2 A;  4GTX A;  3M8Z A;  4LRB A;  3Q3Q A;  4LR2 A;  3WAX A;  1FSU A;  1URB A;  2W5T A;  3LXQ A;  4FDJ A;  4UOP A;  3IDD A;  4CXU A;  5LQQ A;  1AJD A;  1ZED A;  1E33 P;  1KH5 A;  2W5S A;  3BDG A;  3NKO A;  3BDG B;  1K7H A;  5LRN A;  4LRD A;  4LQY A;  3UN5 A;  3WAW A;  1HQA A;  3NKN A;  4LR8 A;  2RH6 A;  3M8W A;  3WAV A;  3MK2 A;  2IFY A;  3DYC A;  1ZEF A;  1ELY A;  2QZU A;  1EQJ A;  1KH9 A;  2IUC A;  5IJQ A;  3MK1 A;  2IUC B;  3NKR A;  3TWZ A;  5IJS A;  2ANH A;  1O99 A;  4FDI A;  4TN0 A;  5GRR A;  4CYS A;  3UNY A;  2ZKT A;  1E2S P;  4B56 A;  4UPL A;  1E3C P;  3KD8 A;  4ZG9 A;  2W5X A;  1O98 A;  1AJB A;  2GSN A;  4MIV A;  3NKP A;  3NKM A;  5EGH A;  1ANJ A;  4KJG A;  4ZG6 A;  4UPK A;  1URA A;  3DPC A;  2W5R A;  2XR9 A;  1AUK A;  4LRA A;  3T01 A;  4UOO A;  5DLV A;  1KHL A;  1HJK A;  5AJ9 A;  3BDF A;  4N7T A;  1SHQ A;  4CXS A;  5LIA A;  2GSO A;  3B5Q A;  4KAV A;  4UPH A;  1AJA A;  5DLT A;  1ED9 A;  1Y6V A;  4CYR A;  3M8Y A;  4KAY A;  4LR7 A;  3IGY B;  4NWX A;  5EGE A;  4GTZ A;  3SZZ A;  4QAX A;  2GLQ A;  4UPI A;  3T02 A;  3NVL A;  3TG0 A;  3OT9 A;  4LRF A;  2X98 A;  4MY4 A;  4LRC A;  1EW2 A;  1Y7A A;  5L0B A;  1EW9 A;  2W5W A;  2G9Y A;  1B8J A;  5HRT A;  5L0E A;  2GSU A;  1SHN A;  4ZGA A;  1KHN A;  1ELX A;  3WAY A;  1ALI A;  1EI6 A;  2XRG A;  3IGZ B;  4KJD A;  3A52 A;  3BDH A;  1ZEB A;  1KHK A;  3CMR A;  4UOR A;  3TX0 A;  1HDH A;  3UN3 A;  1EJJ A;  1ED8 A;  4ZG7 A;  4GTW A;  5C66 A;  1ALH A;  1AJC A;  5L0K A;  1ANI A;  5KXA A;  2W5Q A;  1KHJ A;  3NKQ A;  5DLW A;  1EW8 A;  1ALK A;  3UO0 A;  4CXK A;  3WBH A;  5LRM A;  5GOV A;  4LRE A;  1N2K A;  3M7V A;  2W5V A;  4LR9 A;  4KM4 A;  1N2L A;  1ALJ A;  2VQR A;  4YR1 A;  1P49 A;  2W8D A;  1KH7 A;  5INH A;  1E1Z P;  5TJ3 A;  3T00 A;  3ED4 A;  3E2D A;  2GA3 A;  4MHX A;  3SZY A;  2D1G A; 
#chains in the Genus database with same CATH topology
 1ELZ A;  1KH4 A;  4NWJ A;  5K4P A;  3MK0 A;  2W8S A;  4GTY A;  3UN2 A;  4GTX A;  3M8Z A;  4LRB A;  3Q3Q A;  4LR2 A;  3WAX A;  1FSU A;  1URB A;  2W5T A;  3LXQ A;  4FDJ A;  4UOP A;  3IDD A;  4CXU A;  5LQQ A;  1AJD A;  1ZED A;  1E33 P;  1KH5 A;  2W5S A;  3BDG A;  3NKO A;  3BDG B;  1K7H A;  5LRN A;  4LRD A;  4LQY A;  3UN5 A;  3WAW A;  1HQA A;  3NKN A;  4LR8 A;  2RH6 A;  3M8W A;  3WAV A;  3MK2 A;  2IFY A;  3DYC A;  1ZEF A;  1ELY A;  2QZU A;  1EQJ A;  1KH9 A;  2IUC A;  5IJQ A;  3MK1 A;  2IUC B;  3NKR A;  3TWZ A;  5IJS A;  2ANH A;  1O99 A;  4FDI A;  4TN0 A;  5GRR A;  4CYS A;  3UNY A;  2ZKT A;  1E2S P;  4B56 A;  4UPL A;  1E3C P;  3KD8 A;  4ZG9 A;  2W5X A;  1O98 A;  1AJB A;  2GSN A;  4MIV A;  3NKP A;  3NKM A;  5EGH A;  1ANJ A;  4KJG A;  4ZG6 A;  4UPK A;  1URA A;  3DPC A;  2W5R A;  2XR9 A;  1AUK A;  4LRA A;  3T01 A;  4UOO A;  5DLV A;  1KHL A;  1HJK A;  5AJ9 A;  3BDF A;  4N7T A;  1SHQ A;  4CXS A;  5LIA A;  2GSO A;  3B5Q A;  4KAV A;  4UPH A;  1AJA A;  5DLT A;  1ED9 A;  1Y6V A;  4CYR A;  3M8Y A;  4KAY A;  4LR7 A;  3IGY B;  4NWX A;  5EGE A;  4GTZ A;  3SZZ A;  4QAX A;  2GLQ A;  4UPI A;  3T02 A;  3NVL A;  3TG0 A;  3OT9 A;  4LRF A;  2X98 A;  4MY4 A;  4LRC A;  1EW2 A;  1Y7A A;  5L0B A;  1EW9 A;  2W5W A;  2G9Y A;  1B8J A;  5HRT A;  5L0E A;  2GSU A;  1SHN A;  4ZGA A;  1KHN A;  1ELX A;  3WAY A;  1ALI A;  1EI6 A;  2XRG A;  3IGZ B;  4KJD A;  3A52 A;  3BDH A;  1ZEB A;  1KHK A;  3CMR A;  4UOR A;  3TX0 A;  1HDH A;  3UN3 A;  1EJJ A;  1ED8 A;  4ZG7 A;  4GTW A;  5C66 A;  1ALH A;  1AJC A;  5L0K A;  1ANI A;  5KXA A;  2W5Q A;  1KHJ A;  3NKQ A;  5DLW A;  1EW8 A;  1ALK A;  3UO0 A;  4CXK A;  3WBH A;  5LRM A;  5GOV A;  4LRE A;  1N2K A;  3M7V A;  2W5V A;  4LR9 A;  4KM4 A;  1N2L A;  1ALJ A;  2VQR A;  4YR1 A;  1P49 A;  2W8D A;  1KH7 A;  5INH A;  1E1Z P;  5TJ3 A;  3T00 A;  3ED4 A;  3E2D A;  2GA3 A;  4MHX A;  3SZY A;  2D1G A; 
#chains in the Genus database with same CATH homology
 1ELZ A;  1KH4 A;  4NWJ A;  5K4P A;  3MK0 A;  2W8S A;  4GTY A;  3UN2 A;  4GTX A;  3M8Z A;  4LRB A;  3Q3Q A;  4LR2 A;  3WAX A;  1FSU A;  1URB A;  2W5T A;  3LXQ A;  4FDJ A;  4UOP A;  3IDD A;  4CXU A;  5LQQ A;  1AJD A;  1ZED A;  1E33 P;  1KH5 A;  2W5S A;  3BDG A;  3NKO A;  3BDG B;  1K7H A;  5LRN A;  4LRD A;  4LQY A;  3UN5 A;  3WAW A;  1HQA A;  3NKN A;  4LR8 A;  2RH6 A;  3M8W A;  3WAV A;  3MK2 A;  2IFY A;  3DYC A;  1ZEF A;  1ELY A;  2QZU A;  1EQJ A;  1KH9 A;  2IUC A;  5IJQ A;  3MK1 A;  2IUC B;  3NKR A;  3TWZ A;  5IJS A;  2ANH A;  1O99 A;  4FDI A;  4TN0 A;  5GRR A;  4CYS A;  3UNY A;  2ZKT A;  1E2S P;  4B56 A;  4UPL A;  1E3C P;  3KD8 A;  4ZG9 A;  2W5X A;  1O98 A;  1AJB A;  2GSN A;  4MIV A;  3NKP A;  3NKM A;  5EGH A;  1ANJ A;  4KJG A;  4ZG6 A;  4UPK A;  1URA A;  3DPC A;  2W5R A;  2XR9 A;  1AUK A;  4LRA A;  3T01 A;  4UOO A;  5DLV A;  1KHL A;  1HJK A;  5AJ9 A;  3BDF A;  4N7T A;  1SHQ A;  4CXS A;  5LIA A;  2GSO A;  3B5Q A;  4KAV A;  4UPH A;  1AJA A;  5DLT A;  1ED9 A;  1Y6V A;  4CYR A;  3M8Y A;  4KAY A;  4LR7 A;  3IGY B;  4NWX A;  5EGE A;  4GTZ A;  3SZZ A;  4QAX A;  2GLQ A;  4UPI A;  3T02 A;  3NVL A;  3TG0 A;  3OT9 A;  4LRF A;  2X98 A;  4MY4 A;  4LRC A;  1EW2 A;  1Y7A A;  5L0B A;  1EW9 A;  2W5W A;  2G9Y A;  1B8J A;  5HRT A;  5L0E A;  2GSU A;  1SHN A;  4ZGA A;  1KHN A;  1ELX A;  3WAY A;  1ALI A;  1EI6 A;  2XRG A;  3IGZ B;  4KJD A;  3A52 A;  3BDH A;  1ZEB A;  1KHK A;  3CMR A;  4UOR A;  3TX0 A;  1HDH A;  3UN3 A;  1EJJ A;  1ED8 A;  4ZG7 A;  4GTW A;  5C66 A;  1ALH A;  1AJC A;  5L0K A;  1ANI A;  5KXA A;  2W5Q A;  1KHJ A;  3NKQ A;  5DLW A;  1EW8 A;  1ALK A;  3UO0 A;  4CXK A;  3WBH A;  5LRM A;  5GOV A;  4LRE A;  1N2K A;  3M7V A;  2W5V A;  4LR9 A;  4KM4 A;  1N2L A;  1ALJ A;  2VQR A;  4YR1 A;  1P49 A;  2W8D A;  1KH7 A;  5INH A;  1E1Z P;  5TJ3 A;  3T00 A;  3ED4 A;  3E2D A;  2GA3 A;  4MHX A;  3SZY A;  2D1G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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