3TG0 | Genus

Total Genus 164

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	164
Knots found	KnotProt 2.0: S +3₁
sequence length	440
structure length	440
Chain Sequence	NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography. pubmed doi rcsb
molecule keywords	Alkaline phosphatase
molecule tags	Hydrolase
source organism	Escherichia coli
total genus	164
structure length	440
sequence length	440
chains with identical sequence	B, C, D
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	2011-08-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	3tg0A00

3KD8A 2G9YA 4GTZA 1SHNA 4MHXA 4YR1A 3TG0A 3M8ZA 3NKNA 2GA3A 4CXUA 1ANJA 4UOOA 2GSOA 3A52A 4KM4A 4LRCA 4NWJA 3UO0A 5K4PA 1EJJA 1ALHA 4LRFA 5LRMA 4LRDA 3IGYB 3IGZB 1Y6VA 4CYSA 1ELYA 3T02A 3WAYA 2W8DA 3NKOA 5KXAA 4FDJA 1ZEDA 2W5SA 4GTXA 3T00A 2XRGA 1EW8A 5GOVA 4GTWA 4LR8A 1E33P 2W5WA 1ELZA 1N2KA 4KAVA 1ED8A 1KHLA 5INHA 3B5QA 1AJAA 1EQJA 1FSUA 1O99A 4N7TA 5IJQA 1SHQA 1KH4A 1K7HA 3IDDA 4KAYA 3WBHA 3NKQA 5DLTA 2IUCA 2W5RA 1EW9A 4LQYA 2W5XA 4KJDA 2XR9A 5DLWA 1KH9A 4ZGAA 4ZG6A 4FDIA 1Y7AA 1ED9A 5EGHA 3BDHA 3M7VA 2D1GA 4MIVA 3NKMA 5C66A 1ELXA 2IUCB 4LR9A 5L0EA 5LQQA 3MK2A 4QAXA 3SZYA 1KHKA 4LRAA 3M8WA 4NWXA 2QZUA 1HQAA 1HJKA 3TWZA 2X98A 2ANHA 1ALKA 4CXSA 1AUKA 4UOPA 4UPKA 1KHJA 4UPLA 2W5VA 1O98A 3MK1A 3Q3QA 3TX0A 1URBA 5HRTA 4UORA 2GSNA 3WAVA 4TN0A 4ZG7A 1HDHA 5LIAA 2W5TA 3BDGA 3M8YA 5LRNA 1EW2A 1AJCA 1P49A 2RH6A 1URAA 4KJGA 4UPHA 1AJBA 5AJ9A 3WAWA 4GTYA 1ZEBA 3NKPA 3MK0A 3UN3A 5L0KA 1ZEFA 3UN5A 3NVLA 4MY4A 3LXQA 1KH5A 3DYCA 1KHNA 3BDGB 1E1ZP 1AJDA 3ED4A 4CYRA 4LREA 1ALIA 4B56A 2VQRA 5GRRA 3UNYA 4CXKA 5DLVA 5TJ3A 1E2SP 4UPIA 1ALJA 3SZZA 2W5QA 3BDFA 3UN2A 5IJSA 2ZKTA 1B8JA 2IFYA 2GLQA 3E2DA 1KH7A 1E3CP 1ANIA 3OT9A 1EI6A 4ZG9A 4LRBA 3WAXA 1N2LA 3CMRA 3DPCA 5EGEA 2W8SA 2GSUA 3NKRA 5L0BA 4LR2A 3T01A 4LR7A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3KD8 A;  2G9Y A;  4GTZ A;  1SHN A;  4MHX A;  4YR1 A;  3TG0 A;  3M8Z A;  3NKN A;  2GA3 A;  4CXU A;  1ANJ A;  4UOO A;  2GSO A;  3A52 A;  4KM4 A;  4LRC A;  4NWJ A;  3UO0 A;  5K4P A;  1EJJ A;  1ALH A;  4LRF A;  5LRM A;  4LRD A;  3IGY B;  3IGZ B;  1Y6V A;  4CYS A;  1ELY A;  3T02 A;  3WAY A;  2W8D A;  3NKO A;  5KXA A;  4FDJ A;  1ZED A;  2W5S A;  4GTX A;  3T00 A;  2XRG A;  1EW8 A;  5GOV A;  4GTW A;  4LR8 A;  1E33 P;  2W5W A;  1ELZ A;  1N2K A;  4KAV A;  1ED8 A;  1KHL A;  5INH A;  3B5Q A;  1AJA A;  1EQJ A;  1FSU A;  1O99 A;  4N7T A;  5IJQ A;  1SHQ A;  1KH4 A;  1K7H A;  3IDD A;  4KAY A;  3WBH A;  3NKQ A;  5DLT A;  2IUC A;  2W5R A;  1EW9 A;  4LQY A;  2W5X A;  4KJD A;  2XR9 A;  5DLW A;  1KH9 A;  4ZGA A;  4ZG6 A;  4FDI A;  1Y7A A;  1ED9 A;  5EGH A;  3BDH A;  3M7V A;  2D1G A;  4MIV A;  3NKM A;  5C66 A;  1ELX A;  2IUC B;  4LR9 A;  5L0E A;  5LQQ A;  3MK2 A;  4QAX A;  3SZY A;  1KHK A;  4LRA A;  3M8W A;  4NWX A;  2QZU A;  1HQA A;  1HJK A;  3TWZ A;  2X98 A;  2ANH A;  1ALK A;  4CXS A;  1AUK A;  4UOP A;  4UPK A;  1KHJ A;  4UPL A;  2W5V A;  1O98 A;  3MK1 A;  3Q3Q A;  3TX0 A;  1URB A;  5HRT A;  4UOR A;  2GSN A;  3WAV A;  4TN0 A;  4ZG7 A;  1HDH A;  5LIA A;  2W5T A;  3BDG A;  3M8Y A;  5LRN A;  1EW2 A;  1AJC A;  1P49 A;  2RH6 A;  1URA A;  4KJG A;  4UPH A;  1AJB A;  5AJ9 A;  3WAW A;  4GTY A;  1ZEB A;  3NKP A;  3MK0 A;  3UN3 A;  5L0K A;  1ZEF A;  3UN5 A;  3NVL A;  4MY4 A;  3LXQ A;  1KH5 A;  3DYC A;  1KHN A;  3BDG B;  1E1Z P;  1AJD A;  3ED4 A;  4CYR A;  4LRE A;  1ALI A;  4B56 A;  2VQR A;  5GRR A;  3UNY A;  4CXK A;  5DLV A;  5TJ3 A;  1E2S P;  4UPI A;  1ALJ A;  3SZZ A;  2W5Q A;  3BDF A;  3UN2 A;  5IJS A;  2ZKT A;  1B8J A;  2IFY A;  2GLQ A;  3E2D A;  1KH7 A;  1E3C P;  1ANI A;  3OT9 A;  1EI6 A;  4ZG9 A;  4LRB A;  3WAX A;  1N2L A;  3CMR A;  3DPC A;  5EGE A;  2W8S A;  2GSU A;  3NKR A;  5L0B A;  4LR2 A;  3T01 A;  4LR7 A; 
#chains in the Genus database with same CATH topology
 3KD8 A;  2G9Y A;  4GTZ A;  1SHN A;  4MHX A;  4YR1 A;  3TG0 A;  3M8Z A;  3NKN A;  2GA3 A;  4CXU A;  1ANJ A;  4UOO A;  2GSO A;  3A52 A;  4KM4 A;  4LRC A;  4NWJ A;  3UO0 A;  5K4P A;  1EJJ A;  1ALH A;  4LRF A;  5LRM A;  4LRD A;  3IGY B;  3IGZ B;  1Y6V A;  4CYS A;  1ELY A;  3T02 A;  3WAY A;  2W8D A;  3NKO A;  5KXA A;  4FDJ A;  1ZED A;  2W5S A;  4GTX A;  3T00 A;  2XRG A;  1EW8 A;  5GOV A;  4GTW A;  4LR8 A;  1E33 P;  2W5W A;  1ELZ A;  1N2K A;  4KAV A;  1ED8 A;  1KHL A;  5INH A;  3B5Q A;  1AJA A;  1EQJ A;  1FSU A;  1O99 A;  4N7T A;  5IJQ A;  1SHQ A;  1KH4 A;  1K7H A;  3IDD A;  4KAY A;  3WBH A;  3NKQ A;  5DLT A;  2IUC A;  2W5R A;  1EW9 A;  4LQY A;  2W5X A;  4KJD A;  2XR9 A;  5DLW A;  1KH9 A;  4ZGA A;  4ZG6 A;  4FDI A;  1Y7A A;  1ED9 A;  5EGH A;  3BDH A;  3M7V A;  2D1G A;  4MIV A;  3NKM A;  5C66 A;  1ELX A;  2IUC B;  4LR9 A;  5L0E A;  5LQQ A;  3MK2 A;  4QAX A;  3SZY A;  1KHK A;  4LRA A;  3M8W A;  4NWX A;  2QZU A;  1HQA A;  1HJK A;  3TWZ A;  2X98 A;  2ANH A;  1ALK A;  4CXS A;  1AUK A;  4UOP A;  4UPK A;  1KHJ A;  4UPL A;  2W5V A;  1O98 A;  3MK1 A;  3Q3Q A;  3TX0 A;  1URB A;  5HRT A;  4UOR A;  2GSN A;  3WAV A;  4TN0 A;  4ZG7 A;  1HDH A;  5LIA A;  2W5T A;  3BDG A;  3M8Y A;  5LRN A;  1EW2 A;  1AJC A;  1P49 A;  2RH6 A;  1URA A;  4KJG A;  4UPH A;  1AJB A;  5AJ9 A;  3WAW A;  4GTY A;  1ZEB A;  3NKP A;  3MK0 A;  3UN3 A;  5L0K A;  1ZEF A;  3UN5 A;  3NVL A;  4MY4 A;  3LXQ A;  1KH5 A;  3DYC A;  1KHN A;  3BDG B;  1E1Z P;  1AJD A;  3ED4 A;  4CYR A;  4LRE A;  1ALI A;  4B56 A;  2VQR A;  5GRR A;  3UNY A;  4CXK A;  5DLV A;  5TJ3 A;  1E2S P;  4UPI A;  1ALJ A;  3SZZ A;  2W5Q A;  3BDF A;  3UN2 A;  5IJS A;  2ZKT A;  1B8J A;  2IFY A;  2GLQ A;  3E2D A;  1KH7 A;  1E3C P;  1ANI A;  3OT9 A;  1EI6 A;  4ZG9 A;  4LRB A;  3WAX A;  1N2L A;  3CMR A;  3DPC A;  5EGE A;  2W8S A;  2GSU A;  3NKR A;  5L0B A;  4LR2 A;  3T01 A;  4LR7 A; 
#chains in the Genus database with same CATH homology
 3KD8 A;  2G9Y A;  4GTZ A;  1SHN A;  4MHX A;  4YR1 A;  3TG0 A;  3M8Z A;  3NKN A;  2GA3 A;  4CXU A;  1ANJ A;  4UOO A;  2GSO A;  3A52 A;  4KM4 A;  4LRC A;  4NWJ A;  3UO0 A;  5K4P A;  1EJJ A;  1ALH A;  4LRF A;  5LRM A;  4LRD A;  3IGY B;  3IGZ B;  1Y6V A;  4CYS A;  1ELY A;  3T02 A;  3WAY A;  2W8D A;  3NKO A;  5KXA A;  4FDJ A;  1ZED A;  2W5S A;  4GTX A;  3T00 A;  2XRG A;  1EW8 A;  5GOV A;  4GTW A;  4LR8 A;  1E33 P;  2W5W A;  1ELZ A;  1N2K A;  4KAV A;  1ED8 A;  1KHL A;  5INH A;  3B5Q A;  1AJA A;  1EQJ A;  1FSU A;  1O99 A;  4N7T A;  5IJQ A;  1SHQ A;  1KH4 A;  1K7H A;  3IDD A;  4KAY A;  3WBH A;  3NKQ A;  5DLT A;  2IUC A;  2W5R A;  1EW9 A;  4LQY A;  2W5X A;  4KJD A;  2XR9 A;  5DLW A;  1KH9 A;  4ZGA A;  4ZG6 A;  4FDI A;  1Y7A A;  1ED9 A;  5EGH A;  3BDH A;  3M7V A;  2D1G A;  4MIV A;  3NKM A;  5C66 A;  1ELX A;  2IUC B;  4LR9 A;  5L0E A;  5LQQ A;  3MK2 A;  4QAX A;  3SZY A;  1KHK A;  4LRA A;  3M8W A;  4NWX A;  2QZU A;  1HQA A;  1HJK A;  3TWZ A;  2X98 A;  2ANH A;  1ALK A;  4CXS A;  1AUK A;  4UOP A;  4UPK A;  1KHJ A;  4UPL A;  2W5V A;  1O98 A;  3MK1 A;  3Q3Q A;  3TX0 A;  1URB A;  5HRT A;  4UOR A;  2GSN A;  3WAV A;  4TN0 A;  4ZG7 A;  1HDH A;  5LIA A;  2W5T A;  3BDG A;  3M8Y A;  5LRN A;  1EW2 A;  1AJC A;  1P49 A;  2RH6 A;  1URA A;  4KJG A;  4UPH A;  1AJB A;  5AJ9 A;  3WAW A;  4GTY A;  1ZEB A;  3NKP A;  3MK0 A;  3UN3 A;  5L0K A;  1ZEF A;  3UN5 A;  3NVL A;  4MY4 A;  3LXQ A;  1KH5 A;  3DYC A;  1KHN A;  3BDG B;  1E1Z P;  1AJD A;  3ED4 A;  4CYR A;  4LRE A;  1ALI A;  4B56 A;  2VQR A;  5GRR A;  3UNY A;  4CXK A;  5DLV A;  5TJ3 A;  1E2S P;  4UPI A;  1ALJ A;  3SZZ A;  2W5Q A;  3BDF A;  3UN2 A;  5IJS A;  2ZKT A;  1B8J A;  2IFY A;  2GLQ A;  3E2D A;  1KH7 A;  1E3C P;  1ANI A;  3OT9 A;  1EI6 A;  4ZG9 A;  4LRB A;  3WAX A;  1N2L A;  3CMR A;  3DPC A;  5EGE A;  2W8S A;  2GSU A;  3NKR A;  5L0B A;  4LR2 A;  3T01 A;  4LR7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3TG0A

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations