3TG0 | Genus

Total Genus 164

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	164
Knots found	KnotProt 2.0: S +3₁
sequence length	440
structure length	440
Chain Sequence	NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5d10a2789b70752d6443d575/pdb.gz

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The Resolver thinks Pdb

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Time for openFile(/file/5d10a2789b70752d6443d575/pdb.gz): 1643 ms

reading 440 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

440 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 29 ms

Adding embedded #jmolscript: select ({0:439});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography. pubmed doi rcsb
molecule keywords	Alkaline phosphatase
molecule tags	Hydrolase
source organism	Escherichia coli
total genus	164
structure length	440
sequence length	440
chains with identical sequence	B, C, D
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date	2011-08-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00245	Alk_phosphatase	Alkaline phosphatase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	3tg0A00

4UPLA 3SZYA 1ALKA 1KH9A 1O99A 4UPHA 4GTXA 1O98A 3M8WA 5L0KA 4LREA 5EGHA 2XR9A 3LXQA 3BDHA 2W5RA 4MHXA 2ZKTA 4B56A 3CMRA 1Y7AA 4NWXA 3UNYA 3NKMA 2W5WA 1Y6VA 4CYRA 1ANJA 1EI6A 2IUCA 3NKRA 1N2LA 3M8ZA 5L0EA 1AJDA 1HDHA 2GSOA 3M8YA 4MIVA 5IJSA 3NVLA 1ALJA 1ED8A 3BDGB 3WAYA 1E3CP 1KHKA 5TJ3A 2GSNA 5GOVA 3T02A 3UN3A 3TG0A 2QZUA 1SHNA 3MK1A 1ALIA 3DYCA 5LRMA 2GLQA 3Q3QA 3TWZA 3TX0A 1ELYA 4ZG7A 5DLVA 1FSUA 4KJGA 2X98A 2IUCB 1K7HA 2ANHA 3E2DA 3BDFA 1ZEDA 2RH6A 1ELZA 2D1GA 1AJBA 3B5QA 5EGEA 4CXKA 1KH5A 3IGZB 1ANIA 5AJ9A 2GA3A 2XRGA 5HRTA 3IDDA 1P49A 4FDJA 3WAXA 3SZZA 4LQYA 5INHA 1HQAA 5LRNA 1EJJA 3WAVA 1ED9A 4UOOA 4ZGAA 3UN2A 4KJDA 2W5SA 4LR8A 3T00A 4FDIA 1N2KA 3MK2A 4GTYA 1E2SP 3OT9A 2VQRA 1B8JA 2GSUA 1SHQA 1KH4A 3M7VA 4LRCA 4CYSA 2IFYA 3T01A 4LRBA 4MY4A 4LRFA 4ZG6A 4ZG9A 4UPIA 1E1ZP 4GTWA 3WAWA 4NWJA 3ED4A 1EW8A 3NKNA 2G9YA 4UOPA 1KH7A 4N7TA 3A52A 4KAVA 5IJQA 4LRDA 4TN0A 3DPCA 1AUKA 4UORA 4UPKA 1URBA 4KM4A 5GRRA 3MK0A 1KHLA 1EW2A 5L0BA 1ALHA 4QAXA 4KAYA 1ELXA 1ZEFA 5K4PA 2W8SA 3IGYB 4LR9A 3NKOA 5C66A 1AJAA 5KXAA 1EW9A 3WBHA 1KHNA 1EQJA 2W8DA 4CXSA 2W5TA 4GTZA 4LR7A 3NKPA 5DLTA 4YR1A 5LQQA 5LIAA 4CXUA 2W5QA 1ZEBA 4LR2A 3UN5A 1AJCA 3KD8A 3UO0A 3BDGA 1KHJA 1URAA 3NKQA 5DLWA 1HJKA 1E33P 2W5VA 4LRAA 2W5XA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4UPL A;  3SZY A;  1ALK A;  1KH9 A;  1O99 A;  4UPH A;  4GTX A;  1O98 A;  3M8W A;  5L0K A;  4LRE A;  5EGH A;  2XR9 A;  3LXQ A;  3BDH A;  2W5R A;  4MHX A;  2ZKT A;  4B56 A;  3CMR A;  1Y7A A;  4NWX A;  3UNY A;  3NKM A;  2W5W A;  1Y6V A;  4CYR A;  1ANJ A;  1EI6 A;  2IUC A;  3NKR A;  1N2L A;  3M8Z A;  5L0E A;  1AJD A;  1HDH A;  2GSO A;  3M8Y A;  4MIV A;  5IJS A;  3NVL A;  1ALJ A;  1ED8 A;  3BDG B;  3WAY A;  1E3C P;  1KHK A;  5TJ3 A;  2GSN A;  5GOV A;  3T02 A;  3UN3 A;  3TG0 A;  2QZU A;  1SHN A;  3MK1 A;  1ALI A;  3DYC A;  5LRM A;  2GLQ A;  3Q3Q A;  3TWZ A;  3TX0 A;  1ELY A;  4ZG7 A;  5DLV A;  1FSU A;  4KJG A;  2X98 A;  2IUC B;  1K7H A;  2ANH A;  3E2D A;  3BDF A;  1ZED A;  2RH6 A;  1ELZ A;  2D1G A;  1AJB A;  3B5Q A;  5EGE A;  4CXK A;  1KH5 A;  3IGZ B;  1ANI A;  5AJ9 A;  2GA3 A;  2XRG A;  5HRT A;  3IDD A;  1P49 A;  4FDJ A;  3WAX A;  3SZZ A;  4LQY A;  5INH A;  1HQA A;  5LRN A;  1EJJ A;  3WAV A;  1ED9 A;  4UOO A;  4ZGA A;  3UN2 A;  4KJD A;  2W5S A;  4LR8 A;  3T00 A;  4FDI A;  1N2K A;  3MK2 A;  4GTY A;  1E2S P;  3OT9 A;  2VQR A;  1B8J A;  2GSU A;  1SHQ A;  1KH4 A;  3M7V A;  4LRC A;  4CYS A;  2IFY A;  3T01 A;  4LRB A;  4MY4 A;  4LRF A;  4ZG6 A;  4ZG9 A;  4UPI A;  1E1Z P;  4GTW A;  3WAW A;  4NWJ A;  3ED4 A;  1EW8 A;  3NKN A;  2G9Y A;  4UOP A;  1KH7 A;  4N7T A;  3A52 A;  4KAV A;  5IJQ A;  4LRD A;  4TN0 A;  3DPC A;  1AUK A;  4UOR A;  4UPK A;  1URB A;  4KM4 A;  5GRR A;  3MK0 A;  1KHL A;  1EW2 A;  5L0B A;  1ALH A;  4QAX A;  4KAY A;  1ELX A;  1ZEF A;  5K4P A;  2W8S A;  3IGY B;  4LR9 A;  3NKO A;  5C66 A;  1AJA A;  5KXA A;  1EW9 A;  3WBH A;  1KHN A;  1EQJ A;  2W8D A;  4CXS A;  2W5T A;  4GTZ A;  4LR7 A;  3NKP A;  5DLT A;  4YR1 A;  5LQQ A;  5LIA A;  4CXU A;  2W5Q A;  1ZEB A;  4LR2 A;  3UN5 A;  1AJC A;  3KD8 A;  3UO0 A;  3BDG A;  1KHJ A;  1URA A;  3NKQ A;  5DLW A;  1HJK A;  1E33 P;  2W5V A;  4LRA A;  2W5X A; 
#chains in the Genus database with same CATH topology
 4UPL A;  3SZY A;  1ALK A;  1KH9 A;  1O99 A;  4UPH A;  4GTX A;  1O98 A;  3M8W A;  5L0K A;  4LRE A;  5EGH A;  2XR9 A;  3LXQ A;  3BDH A;  2W5R A;  4MHX A;  2ZKT A;  4B56 A;  3CMR A;  1Y7A A;  4NWX A;  3UNY A;  3NKM A;  2W5W A;  1Y6V A;  4CYR A;  1ANJ A;  1EI6 A;  2IUC A;  3NKR A;  1N2L A;  3M8Z A;  5L0E A;  1AJD A;  1HDH A;  2GSO A;  3M8Y A;  4MIV A;  5IJS A;  3NVL A;  1ALJ A;  1ED8 A;  3BDG B;  3WAY A;  1E3C P;  1KHK A;  5TJ3 A;  2GSN A;  5GOV A;  3T02 A;  3UN3 A;  3TG0 A;  2QZU A;  1SHN A;  3MK1 A;  1ALI A;  3DYC A;  5LRM A;  2GLQ A;  3Q3Q A;  3TWZ A;  3TX0 A;  1ELY A;  4ZG7 A;  5DLV A;  1FSU A;  4KJG A;  2X98 A;  2IUC B;  1K7H A;  2ANH A;  3E2D A;  3BDF A;  1ZED A;  2RH6 A;  1ELZ A;  2D1G A;  1AJB A;  3B5Q A;  5EGE A;  4CXK A;  1KH5 A;  3IGZ B;  1ANI A;  5AJ9 A;  2GA3 A;  2XRG A;  5HRT A;  3IDD A;  1P49 A;  4FDJ A;  3WAX A;  3SZZ A;  4LQY A;  5INH A;  1HQA A;  5LRN A;  1EJJ A;  3WAV A;  1ED9 A;  4UOO A;  4ZGA A;  3UN2 A;  4KJD A;  2W5S A;  4LR8 A;  3T00 A;  4FDI A;  1N2K A;  3MK2 A;  4GTY A;  1E2S P;  3OT9 A;  2VQR A;  1B8J A;  2GSU A;  1SHQ A;  1KH4 A;  3M7V A;  4LRC A;  4CYS A;  2IFY A;  3T01 A;  4LRB A;  4MY4 A;  4LRF A;  4ZG6 A;  4ZG9 A;  4UPI A;  1E1Z P;  4GTW A;  3WAW A;  4NWJ A;  3ED4 A;  1EW8 A;  3NKN A;  2G9Y A;  4UOP A;  1KH7 A;  4N7T A;  3A52 A;  4KAV A;  5IJQ A;  4LRD A;  4TN0 A;  3DPC A;  1AUK A;  4UOR A;  4UPK A;  1URB A;  4KM4 A;  5GRR A;  3MK0 A;  1KHL A;  1EW2 A;  5L0B A;  1ALH A;  4QAX A;  4KAY A;  1ELX A;  1ZEF A;  5K4P A;  2W8S A;  3IGY B;  4LR9 A;  3NKO A;  5C66 A;  1AJA A;  5KXA A;  1EW9 A;  3WBH A;  1KHN A;  1EQJ A;  2W8D A;  4CXS A;  2W5T A;  4GTZ A;  4LR7 A;  3NKP A;  5DLT A;  4YR1 A;  5LQQ A;  5LIA A;  4CXU A;  2W5Q A;  1ZEB A;  4LR2 A;  3UN5 A;  1AJC A;  3KD8 A;  3UO0 A;  3BDG A;  1KHJ A;  1URA A;  3NKQ A;  5DLW A;  1HJK A;  1E33 P;  2W5V A;  4LRA A;  2W5X A; 
#chains in the Genus database with same CATH homology
 4UPL A;  3SZY A;  1ALK A;  1KH9 A;  1O99 A;  4UPH A;  4GTX A;  1O98 A;  3M8W A;  5L0K A;  4LRE A;  5EGH A;  2XR9 A;  3LXQ A;  3BDH A;  2W5R A;  4MHX A;  2ZKT A;  4B56 A;  3CMR A;  1Y7A A;  4NWX A;  3UNY A;  3NKM A;  2W5W A;  1Y6V A;  4CYR A;  1ANJ A;  1EI6 A;  2IUC A;  3NKR A;  1N2L A;  3M8Z A;  5L0E A;  1AJD A;  1HDH A;  2GSO A;  3M8Y A;  4MIV A;  5IJS A;  3NVL A;  1ALJ A;  1ED8 A;  3BDG B;  3WAY A;  1E3C P;  1KHK A;  5TJ3 A;  2GSN A;  5GOV A;  3T02 A;  3UN3 A;  3TG0 A;  2QZU A;  1SHN A;  3MK1 A;  1ALI A;  3DYC A;  5LRM A;  2GLQ A;  3Q3Q A;  3TWZ A;  3TX0 A;  1ELY A;  4ZG7 A;  5DLV A;  1FSU A;  4KJG A;  2X98 A;  2IUC B;  1K7H A;  2ANH A;  3E2D A;  3BDF A;  1ZED A;  2RH6 A;  1ELZ A;  2D1G A;  1AJB A;  3B5Q A;  5EGE A;  4CXK A;  1KH5 A;  3IGZ B;  1ANI A;  5AJ9 A;  2GA3 A;  2XRG A;  5HRT A;  3IDD A;  1P49 A;  4FDJ A;  3WAX A;  3SZZ A;  4LQY A;  5INH A;  1HQA A;  5LRN A;  1EJJ A;  3WAV A;  1ED9 A;  4UOO A;  4ZGA A;  3UN2 A;  4KJD A;  2W5S A;  4LR8 A;  3T00 A;  4FDI A;  1N2K A;  3MK2 A;  4GTY A;  1E2S P;  3OT9 A;  2VQR A;  1B8J A;  2GSU A;  1SHQ A;  1KH4 A;  3M7V A;  4LRC A;  4CYS A;  2IFY A;  3T01 A;  4LRB A;  4MY4 A;  4LRF A;  4ZG6 A;  4ZG9 A;  4UPI A;  1E1Z P;  4GTW A;  3WAW A;  4NWJ A;  3ED4 A;  1EW8 A;  3NKN A;  2G9Y A;  4UOP A;  1KH7 A;  4N7T A;  3A52 A;  4KAV A;  5IJQ A;  4LRD A;  4TN0 A;  3DPC A;  1AUK A;  4UOR A;  4UPK A;  1URB A;  4KM4 A;  5GRR A;  3MK0 A;  1KHL A;  1EW2 A;  5L0B A;  1ALH A;  4QAX A;  4KAY A;  1ELX A;  1ZEF A;  5K4P A;  2W8S A;  3IGY B;  4LR9 A;  3NKO A;  5C66 A;  1AJA A;  5KXA A;  1EW9 A;  3WBH A;  1KHN A;  1EQJ A;  2W8D A;  4CXS A;  2W5T A;  4GTZ A;  4LR7 A;  3NKP A;  5DLT A;  4YR1 A;  5LQQ A;  5LIA A;  4CXU A;  2W5Q A;  1ZEB A;  4LR2 A;  3UN5 A;  1AJC A;  3KD8 A;  3UO0 A;  3BDG A;  1KHJ A;  1URA A;  3NKQ A;  5DLW A;  1HJK A;  1E33 P;  2W5V A;  4LRA A;  2W5X A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3TG0A

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations