3TG0A

E. coli alkaline phosphatase with bound inorganic phosphate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
Knots found
sequence length
440
structure length
440
Chain Sequence
NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Alkaline phosphatase
total genus 164
structure length 440
sequence length 440
chains with identical sequence B, C, D
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3tg0A00
1ELZA 2W5RA 2W8SA 1Y6VA 1EI6A 5KXAA 2ANHA 1ALKA 4LR7A 3A52A 1KH9A 1E2SP 5AJ9A 3IGYB 1HJKA 4ZGAA 4ZG7A 1O99A 1FSUA 4CYRA 1AJDA 3T02A 1HDHA 5LIAA 2W5TA 4TN0A 3M8YA 4MHXA 4LR2A 3TX0A 4LRDA 5C66A 1KHKA 3BDFA 4ZG9A 3WAVA 4N7TA 1ZEFA 3IDDA 2G9YA 1ED9A 5IJQA 4KAYA 4CXKA 3B5QA 1K7HA 1E33P 3BDHA 1KH4A 4GTXA 1EQJA 3UN2A 2GSUA 2VQRA 1ZEDA 3NKOA 4FDJA 4KJDA 4UOPA 3BDGA 2ZKTA 5DLWA 4CYSA 1KHNA 3NKMA 1ANIA 2QZUA 2W8DA 3KD8A 3BDGB 3LXQA 3NKQA 5INHA 2W5XA 1ELYA 3M8ZA 3ED4A 5LRMA 4GTYA 2W5QA 2XRGA 2W5VA 1O98A 2W5SA 3DPCA 3WAXA 1KH7A 3MK2A 5K4PA 4YR1A 3UNYA 4CXSA 2X98A 2GSOA 3WAWA 1HQAA 5DLVA 3UN3A 3OT9A 3SZZA 4LR8A 5LQQA 1EW9A 3MK0A 4UORA 3SZYA 5L0KA 4LR9A 2XR9A 5TJ3A 3DYCA 1Y7AA 3TG0A 4FDIA 3NKNA 4CXUA 3WBHA 2W5WA 1ELXA 3UO0A 4MY4A 3E2DA 4NWXA 5GOVA 1AJAA 4KJGA 4ZG6A 3M8WA 4LRBA 5HRTA 5LRNA 1KHJA 2GA3A 4KM4A 1AUKA 3NKPA 1URAA 3UN5A 1AJCA 2IFYA 1EW8A 4LRCA 1P49A 3NVLA 1URBA 2D1GA 4UPKA 5EGHA 2GLQA 1ED8A 5L0BA 5IJSA 1ANJA 4GTWA 5GRRA 2GSNA 1AJBA 4MIVA 4NWJA 1ALJA 3TWZA 4UPLA 5EGEA 4UPHA 1N2KA 2IUCA 1KHLA 1N2LA 2RH6A 4GTZA 2IUCB 1SHNA 4LQYA 1EJJA 4UPIA 1E3CP 3IGZB 5DLTA 1EW2A 3NKRA 4KAVA 3CMRA 3T00A 4UOOA 3Q3QA 1SHQA 1ZEBA 1ALIA 3T01A 4LREA 1KH5A 4QAXA 4LRAA 4B56A 1B8JA 1E1ZP 4LRFA 3M7VA 3MK1A 5L0EA 3WAYA 1ALHA
chains in the Genus database with same CATH superfamily
1ELZA 2W5RA 2W8SA 1Y6VA 1EI6A 5KXAA 2ANHA 1ALKA 4LR7A 3A52A 1KH9A 1E2SP 5AJ9A 3IGYB 1HJKA 4ZGAA 4ZG7A 1O99A 1FSUA 4CYRA 1AJDA 3T02A 1HDHA 5LIAA 2W5TA 4TN0A 3M8YA 4MHXA 4LR2A 3TX0A 4LRDA 5C66A 1KHKA 3BDFA 4ZG9A 3WAVA 4N7TA 1ZEFA 3IDDA 2G9YA 1ED9A 5IJQA 4KAYA 4CXKA 3B5QA 1K7HA 1E33P 3BDHA 1KH4A 4GTXA 1EQJA 3UN2A 2GSUA 2VQRA 1ZEDA 3NKOA 4FDJA 4KJDA 4UOPA 3BDGA 2ZKTA 5DLWA 4CYSA 1KHNA 3NKMA 1ANIA 2QZUA 2W8DA 3KD8A 3BDGB 3LXQA 3NKQA 5INHA 2W5XA 1ELYA 3M8ZA 3ED4A 5LRMA 4GTYA 2W5QA 2XRGA 2W5VA 1O98A 2W5SA 3DPCA 3WAXA 1KH7A 3MK2A 5K4PA 4YR1A 3UNYA 4CXSA 2X98A 2GSOA 3WAWA 1HQAA 5DLVA 3UN3A 3OT9A 3SZZA 4LR8A 5LQQA 1EW9A 3MK0A 4UORA 3SZYA 5L0KA 4LR9A 2XR9A 5TJ3A 3DYCA 1Y7AA 3TG0A 4FDIA 3NKNA 4CXUA 3WBHA 2W5WA 1ELXA 3UO0A 4MY4A 3E2DA 4NWXA 5GOVA 1AJAA 4KJGA 4ZG6A 3M8WA 4LRBA 5HRTA 5LRNA 1KHJA 2GA3A 4KM4A 1AUKA 3NKPA 1URAA 3UN5A 1AJCA 2IFYA 1EW8A 4LRCA 1P49A 3NVLA 1URBA 2D1GA 4UPKA 5EGHA 2GLQA 1ED8A 5L0BA 5IJSA 1ANJA 4GTWA 5GRRA 2GSNA 1AJBA 4MIVA 4NWJA 1ALJA 3TWZA 4UPLA 5EGEA 4UPHA 1N2KA 2IUCA 1KHLA 1N2LA 2RH6A 4GTZA 2IUCB 1SHNA 4LQYA 1EJJA 4UPIA 1E3CP 3IGZB 5DLTA 1EW2A 3NKRA 4KAVA 3CMRA 3T00A 4UOOA 3Q3QA 1SHQA 1ZEBA 1ALIA 3T01A 4LREA 1KH5A 4QAXA 4LRAA 4B56A 1B8JA 1E1ZP 4LRFA 3M7VA 3MK1A 5L0EA 3WAYA 1ALHA
chains in the Genus database with same CATH topology
1ELZA 2W5RA 2W8SA 1Y6VA 1EI6A 5KXAA 2ANHA 1ALKA 4LR7A 3A52A 1KH9A 1E2SP 5AJ9A 3IGYB 1HJKA 4ZGAA 4ZG7A 1O99A 1FSUA 4CYRA 1AJDA 3T02A 1HDHA 5LIAA 2W5TA 4TN0A 3M8YA 4MHXA 4LR2A 3TX0A 4LRDA 5C66A 1KHKA 3BDFA 4ZG9A 3WAVA 4N7TA 1ZEFA 3IDDA 2G9YA 1ED9A 5IJQA 4KAYA 4CXKA 3B5QA 1K7HA 1E33P 3BDHA 1KH4A 4GTXA 1EQJA 3UN2A 2GSUA 2VQRA 1ZEDA 3NKOA 4FDJA 4KJDA 4UOPA 3BDGA 2ZKTA 5DLWA 4CYSA 1KHNA 3NKMA 1ANIA 2QZUA 2W8DA 3KD8A 3BDGB 3LXQA 3NKQA 5INHA 2W5XA 1ELYA 3M8ZA 3ED4A 5LRMA 4GTYA 2W5QA 2XRGA 2W5VA 1O98A 2W5SA 3DPCA 3WAXA 1KH7A 3MK2A 5K4PA 4YR1A 3UNYA 4CXSA 2X98A 2GSOA 3WAWA 1HQAA 5DLVA 3UN3A 3OT9A 3SZZA 4LR8A 5LQQA 1EW9A 3MK0A 4UORA 3SZYA 5L0KA 4LR9A 2XR9A 5TJ3A 3DYCA 1Y7AA 3TG0A 4FDIA 3NKNA 4CXUA 3WBHA 2W5WA 1ELXA 3UO0A 4MY4A 3E2DA 4NWXA 5GOVA 1AJAA 4KJGA 4ZG6A 3M8WA 4LRBA 5HRTA 5LRNA 1KHJA 2GA3A 4KM4A 1AUKA 3NKPA 1URAA 3UN5A 1AJCA 2IFYA 1EW8A 4LRCA 1P49A 3NVLA 1URBA 2D1GA 4UPKA 5EGHA 2GLQA 1ED8A 5L0BA 5IJSA 1ANJA 4GTWA 5GRRA 2GSNA 1AJBA 4MIVA 4NWJA 1ALJA 3TWZA 4UPLA 5EGEA 4UPHA 1N2KA 2IUCA 1KHLA 1N2LA 2RH6A 4GTZA 2IUCB 1SHNA 4LQYA 1EJJA 4UPIA 1E3CP 3IGZB 5DLTA 1EW2A 3NKRA 4KAVA 3CMRA 3T00A 4UOOA 3Q3QA 1SHQA 1ZEBA 1ALIA 3T01A 4LREA 1KH5A 4QAXA 4LRAA 4B56A 1B8JA 1E1ZP 4LRFA 3M7VA 3MK1A 5L0EA 3WAYA 1ALHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ELZ A;  2W5R A;  2W8S A;  1Y6V A;  1EI6 A;  5KXA A;  2ANH A;  1ALK A;  4LR7 A;  3A52 A;  1KH9 A;  1E2S P;  5AJ9 A;  3IGY B;  1HJK A;  4ZGA A;  4ZG7 A;  1O99 A;  1FSU A;  4CYR A;  1AJD A;  3T02 A;  1HDH A;  5LIA A;  2W5T A;  4TN0 A;  3M8Y A;  4MHX A;  4LR2 A;  3TX0 A;  4LRD A;  5C66 A;  1KHK A;  3BDF A;  4ZG9 A;  3WAV A;  4N7T A;  1ZEF A;  3IDD A;  2G9Y A;  1ED9 A;  5IJQ A;  4KAY A;  4CXK A;  3B5Q A;  1K7H A;  1E33 P;  3BDH A;  1KH4 A;  4GTX A;  1EQJ A;  3UN2 A;  2GSU A;  2VQR A;  1ZED A;  3NKO A;  4FDJ A;  4KJD A;  4UOP A;  3BDG A;  2ZKT A;  5DLW A;  4CYS A;  1KHN A;  3NKM A;  1ANI A;  2QZU A;  2W8D A;  3KD8 A;  3BDG B;  3LXQ A;  3NKQ A;  5INH A;  2W5X A;  1ELY A;  3M8Z A;  3ED4 A;  5LRM A;  4GTY A;  2W5Q A;  2XRG A;  2W5V A;  1O98 A;  2W5S A;  3DPC A;  3WAX A;  1KH7 A;  3MK2 A;  5K4P A;  4YR1 A;  3UNY A;  4CXS A;  2X98 A;  2GSO A;  3WAW A;  1HQA A;  5DLV A;  3UN3 A;  3OT9 A;  3SZZ A;  4LR8 A;  5LQQ A;  1EW9 A;  3MK0 A;  4UOR A;  3SZY A;  5L0K A;  4LR9 A;  2XR9 A;  5TJ3 A;  3DYC A;  1Y7A A;  3TG0 A;  4FDI A;  3NKN A;  4CXU A;  3WBH A;  2W5W A;  1ELX A;  3UO0 A;  4MY4 A;  3E2D A;  4NWX A;  5GOV A;  1AJA A;  4KJG A;  4ZG6 A;  3M8W A;  4LRB A;  5HRT A;  5LRN A;  1KHJ A;  2GA3 A;  4KM4 A;  1AUK A;  3NKP A;  1URA A;  3UN5 A;  1AJC A;  2IFY A;  1EW8 A;  4LRC A;  1P49 A;  3NVL A;  1URB A;  2D1G A;  4UPK A;  5EGH A;  2GLQ A;  1ED8 A;  5L0B A;  5IJS A;  1ANJ A;  4GTW A;  5GRR A;  2GSN A;  1AJB A;  4MIV A;  4NWJ A;  1ALJ A;  3TWZ A;  4UPL A;  5EGE A;  4UPH A;  1N2K A;  2IUC A;  1KHL A;  1N2L A;  2RH6 A;  4GTZ A;  2IUC B;  1SHN A;  4LQY A;  1EJJ A;  4UPI A;  1E3C P;  3IGZ B;  5DLT A;  1EW2 A;  3NKR A;  4KAV A;  3CMR A;  3T00 A;  4UOO A;  3Q3Q A;  1SHQ A;  1ZEB A;  1ALI A;  3T01 A;  4LRE A;  1KH5 A;  4QAX A;  4LRA A;  4B56 A;  1B8J A;  1E1Z P;  4LRF A;  3M7V A;  3MK1 A;  5L0E A;  3WAY A;  1ALH A; 
#chains in the Genus database with same CATH topology
 1ELZ A;  2W5R A;  2W8S A;  1Y6V A;  1EI6 A;  5KXA A;  2ANH A;  1ALK A;  4LR7 A;  3A52 A;  1KH9 A;  1E2S P;  5AJ9 A;  3IGY B;  1HJK A;  4ZGA A;  4ZG7 A;  1O99 A;  1FSU A;  4CYR A;  1AJD A;  3T02 A;  1HDH A;  5LIA A;  2W5T A;  4TN0 A;  3M8Y A;  4MHX A;  4LR2 A;  3TX0 A;  4LRD A;  5C66 A;  1KHK A;  3BDF A;  4ZG9 A;  3WAV A;  4N7T A;  1ZEF A;  3IDD A;  2G9Y A;  1ED9 A;  5IJQ A;  4KAY A;  4CXK A;  3B5Q A;  1K7H A;  1E33 P;  3BDH A;  1KH4 A;  4GTX A;  1EQJ A;  3UN2 A;  2GSU A;  2VQR A;  1ZED A;  3NKO A;  4FDJ A;  4KJD A;  4UOP A;  3BDG A;  2ZKT A;  5DLW A;  4CYS A;  1KHN A;  3NKM A;  1ANI A;  2QZU A;  2W8D A;  3KD8 A;  3BDG B;  3LXQ A;  3NKQ A;  5INH A;  2W5X A;  1ELY A;  3M8Z A;  3ED4 A;  5LRM A;  4GTY A;  2W5Q A;  2XRG A;  2W5V A;  1O98 A;  2W5S A;  3DPC A;  3WAX A;  1KH7 A;  3MK2 A;  5K4P A;  4YR1 A;  3UNY A;  4CXS A;  2X98 A;  2GSO A;  3WAW A;  1HQA A;  5DLV A;  3UN3 A;  3OT9 A;  3SZZ A;  4LR8 A;  5LQQ A;  1EW9 A;  3MK0 A;  4UOR A;  3SZY A;  5L0K A;  4LR9 A;  2XR9 A;  5TJ3 A;  3DYC A;  1Y7A A;  3TG0 A;  4FDI A;  3NKN A;  4CXU A;  3WBH A;  2W5W A;  1ELX A;  3UO0 A;  4MY4 A;  3E2D A;  4NWX A;  5GOV A;  1AJA A;  4KJG A;  4ZG6 A;  3M8W A;  4LRB A;  5HRT A;  5LRN A;  1KHJ A;  2GA3 A;  4KM4 A;  1AUK A;  3NKP A;  1URA A;  3UN5 A;  1AJC A;  2IFY A;  1EW8 A;  4LRC A;  1P49 A;  3NVL A;  1URB A;  2D1G A;  4UPK A;  5EGH A;  2GLQ A;  1ED8 A;  5L0B A;  5IJS A;  1ANJ A;  4GTW A;  5GRR A;  2GSN A;  1AJB A;  4MIV A;  4NWJ A;  1ALJ A;  3TWZ A;  4UPL A;  5EGE A;  4UPH A;  1N2K A;  2IUC A;  1KHL A;  1N2L A;  2RH6 A;  4GTZ A;  2IUC B;  1SHN A;  4LQY A;  1EJJ A;  4UPI A;  1E3C P;  3IGZ B;  5DLT A;  1EW2 A;  3NKR A;  4KAV A;  3CMR A;  3T00 A;  4UOO A;  3Q3Q A;  1SHQ A;  1ZEB A;  1ALI A;  3T01 A;  4LRE A;  1KH5 A;  4QAX A;  4LRA A;  4B56 A;  1B8J A;  1E1Z P;  4LRF A;  3M7V A;  3MK1 A;  5L0E A;  3WAY A;  1ALH A; 
#chains in the Genus database with same CATH homology
 1ELZ A;  2W5R A;  2W8S A;  1Y6V A;  1EI6 A;  5KXA A;  2ANH A;  1ALK A;  4LR7 A;  3A52 A;  1KH9 A;  1E2S P;  5AJ9 A;  3IGY B;  1HJK A;  4ZGA A;  4ZG7 A;  1O99 A;  1FSU A;  4CYR A;  1AJD A;  3T02 A;  1HDH A;  5LIA A;  2W5T A;  4TN0 A;  3M8Y A;  4MHX A;  4LR2 A;  3TX0 A;  4LRD A;  5C66 A;  1KHK A;  3BDF A;  4ZG9 A;  3WAV A;  4N7T A;  1ZEF A;  3IDD A;  2G9Y A;  1ED9 A;  5IJQ A;  4KAY A;  4CXK A;  3B5Q A;  1K7H A;  1E33 P;  3BDH A;  1KH4 A;  4GTX A;  1EQJ A;  3UN2 A;  2GSU A;  2VQR A;  1ZED A;  3NKO A;  4FDJ A;  4KJD A;  4UOP A;  3BDG A;  2ZKT A;  5DLW A;  4CYS A;  1KHN A;  3NKM A;  1ANI A;  2QZU A;  2W8D A;  3KD8 A;  3BDG B;  3LXQ A;  3NKQ A;  5INH A;  2W5X A;  1ELY A;  3M8Z A;  3ED4 A;  5LRM A;  4GTY A;  2W5Q A;  2XRG A;  2W5V A;  1O98 A;  2W5S A;  3DPC A;  3WAX A;  1KH7 A;  3MK2 A;  5K4P A;  4YR1 A;  3UNY A;  4CXS A;  2X98 A;  2GSO A;  3WAW A;  1HQA A;  5DLV A;  3UN3 A;  3OT9 A;  3SZZ A;  4LR8 A;  5LQQ A;  1EW9 A;  3MK0 A;  4UOR A;  3SZY A;  5L0K A;  4LR9 A;  2XR9 A;  5TJ3 A;  3DYC A;  1Y7A A;  3TG0 A;  4FDI A;  3NKN A;  4CXU A;  3WBH A;  2W5W A;  1ELX A;  3UO0 A;  4MY4 A;  3E2D A;  4NWX A;  5GOV A;  1AJA A;  4KJG A;  4ZG6 A;  3M8W A;  4LRB A;  5HRT A;  5LRN A;  1KHJ A;  2GA3 A;  4KM4 A;  1AUK A;  3NKP A;  1URA A;  3UN5 A;  1AJC A;  2IFY A;  1EW8 A;  4LRC A;  1P49 A;  3NVL A;  1URB A;  2D1G A;  4UPK A;  5EGH A;  2GLQ A;  1ED8 A;  5L0B A;  5IJS A;  1ANJ A;  4GTW A;  5GRR A;  2GSN A;  1AJB A;  4MIV A;  4NWJ A;  1ALJ A;  3TWZ A;  4UPL A;  5EGE A;  4UPH A;  1N2K A;  2IUC A;  1KHL A;  1N2L A;  2RH6 A;  4GTZ A;  2IUC B;  1SHN A;  4LQY A;  1EJJ A;  4UPI A;  1E3C P;  3IGZ B;  5DLT A;  1EW2 A;  3NKR A;  4KAV A;  3CMR A;  3T00 A;  4UOO A;  3Q3Q A;  1SHQ A;  1ZEB A;  1ALI A;  3T01 A;  4LRE A;  1KH5 A;  4QAX A;  4LRA A;  4B56 A;  1B8J A;  1E1Z P;  4LRF A;  3M7V A;  3MK1 A;  5L0E A;  3WAY A;  1ALH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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