3TG0A

E. coli alkaline phosphatase with bound inorganic phosphate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
Knots found
sequence length
440
structure length
440
Chain Sequence
NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Alkaline phosphatase
total genus 164
structure length 440
sequence length 440
chains with identical sequence B, C, D
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3tg0A00
4LR9A 1ED9A 1SHQA 5TJ3A 1KH4A 4CYSA 1N2KA 4LREA 3BDFA 1EW9A 3TG0A 1EW2A 2ANHA 4LRDA 5GOVA 4YR1A 3MK1A 1N2LA 3M8ZA 1KHKA 3NKNA 1SHNA 4LRFA 1EQJA 3SZZA 4UORA 5LRNA 4LR7A 3E2DA 3UN3A 4CYRA 2W5VA 4KM4A 2G9YA 1E33P 4CXSA 2W5WA 4LQYA 5EGHA 1K7HA 1ALIA 1P49A 4N7TA 4UOPA 3BDGA 2XRGA 3ED4A 2W5TA 4FDJA 4LRAA 5AJ9A 1EW8A 1HDHA 3IGYB 4GTYA 1B8JA 4LR2A 4LRCA 4UPLA 5IJSA 5L0BA 4NWXA 2GSOA 3NKPA 3NVLA 1ELYA 1HQAA 1ELZA 1HJKA 2W8SA 4UPHA 5LRMA 5L0EA 2W8DA 4TN0A 3B5QA 3IGZB 3A52A 1AUKA 3DYCA 3T01A 4UPIA 1KHLA 4ZG9A 3SZYA 1E2SP 4CXUA 5LQQA 4NWJA 5KXAA 3T00A 4GTWA 5K4PA 4ZGAA 3WBHA 3WAXA 1ED8A 1ZEBA 5GRRA 1ANIA 1URAA 3NKQA 2RH6A 2IUCB 4UPKA 4KAVA 3OT9A 1KHJA 3M8YA 1ANJA 1URBA 5IJQA 4FDIA 3KD8A 4MIVA 5C66A 1AJBA 5DLTA 1ZEDA 4LRBA 2IUCA 3T02A 3NKMA 4MY4A 2VQRA 5DLWA 2D1GA 1ALHA 1E3CP 1FSUA 4KAYA 2XR9A 5EGEA 4GTZA 3BDHA 1EJJA 2W5QA 1KH5A 1AJCA 5LIAA 1KHNA 3TWZA 2W5RA 1KH7A 3IDDA 3UNYA 3UO0A 4KJGA 4KJDA 4LR8A 3M8WA 3LXQA 2GA3A 4CXKA 3WAVA 2W5SA 2X98A 3WAYA 1KH9A 3UN5A 2ZKTA 3DPCA 1ELXA 3CMRA 4QAXA 4ZG6A 5DLVA 4ZG7A 3UN2A 1E1ZP 1ALKA 5L0KA 3M7VA 3TX0A 2GSUA 2GLQA 5INHA 3BDGB 2QZUA 4UOOA 1AJDA 1Y7AA 3NKRA 1EI6A 4MHXA 5HRTA 1Y6VA 3MK0A 3NKOA 1ALJA 3WAWA 4B56A 1AJAA 1O98A 1ZEFA 2GSNA 2W5XA 1O99A 2IFYA 4GTXA 3MK2A 3Q3QA
chains in the Genus database with same CATH superfamily
4LR9A 1ED9A 1SHQA 5TJ3A 1KH4A 4CYSA 1N2KA 4LREA 3BDFA 1EW9A 3TG0A 1EW2A 2ANHA 4LRDA 5GOVA 4YR1A 3MK1A 1N2LA 3M8ZA 1KHKA 3NKNA 1SHNA 4LRFA 1EQJA 3SZZA 4UORA 5LRNA 4LR7A 3E2DA 3UN3A 4CYRA 2W5VA 4KM4A 2G9YA 1E33P 4CXSA 2W5WA 4LQYA 5EGHA 1K7HA 1ALIA 1P49A 4N7TA 4UOPA 3BDGA 2XRGA 3ED4A 2W5TA 4FDJA 4LRAA 5AJ9A 1EW8A 1HDHA 3IGYB 4GTYA 1B8JA 4LR2A 4LRCA 4UPLA 5IJSA 5L0BA 4NWXA 2GSOA 3NKPA 3NVLA 1ELYA 1HQAA 1ELZA 1HJKA 2W8SA 4UPHA 5LRMA 5L0EA 2W8DA 4TN0A 3B5QA 3IGZB 3A52A 1AUKA 3DYCA 3T01A 4UPIA 1KHLA 4ZG9A 3SZYA 1E2SP 4CXUA 5LQQA 4NWJA 5KXAA 3T00A 4GTWA 5K4PA 4ZGAA 3WBHA 3WAXA 1ED8A 1ZEBA 5GRRA 1ANIA 1URAA 3NKQA 2RH6A 2IUCB 4UPKA 4KAVA 3OT9A 1KHJA 3M8YA 1ANJA 1URBA 5IJQA 4FDIA 3KD8A 4MIVA 5C66A 1AJBA 5DLTA 1ZEDA 4LRBA 2IUCA 3T02A 3NKMA 4MY4A 2VQRA 5DLWA 2D1GA 1ALHA 1E3CP 1FSUA 4KAYA 2XR9A 5EGEA 4GTZA 3BDHA 1EJJA 2W5QA 1KH5A 1AJCA 5LIAA 1KHNA 3TWZA 2W5RA 1KH7A 3IDDA 3UNYA 3UO0A 4KJGA 4KJDA 4LR8A 3M8WA 3LXQA 2GA3A 4CXKA 3WAVA 2W5SA 2X98A 3WAYA 1KH9A 3UN5A 2ZKTA 3DPCA 1ELXA 3CMRA 4QAXA 4ZG6A 5DLVA 4ZG7A 3UN2A 1E1ZP 1ALKA 5L0KA 3M7VA 3TX0A 2GSUA 2GLQA 5INHA 3BDGB 2QZUA 4UOOA 1AJDA 1Y7AA 3NKRA 1EI6A 4MHXA 5HRTA 1Y6VA 3MK0A 3NKOA 1ALJA 3WAWA 4B56A 1AJAA 1O98A 1ZEFA 2GSNA 2W5XA 1O99A 2IFYA 4GTXA 3MK2A 3Q3QA
chains in the Genus database with same CATH topology
4LR9A 1ED9A 1SHQA 5TJ3A 1KH4A 4CYSA 1N2KA 4LREA 3BDFA 1EW9A 3TG0A 1EW2A 2ANHA 4LRDA 5GOVA 4YR1A 3MK1A 1N2LA 3M8ZA 1KHKA 3NKNA 1SHNA 4LRFA 1EQJA 3SZZA 4UORA 5LRNA 4LR7A 3E2DA 3UN3A 4CYRA 2W5VA 4KM4A 2G9YA 1E33P 4CXSA 2W5WA 4LQYA 5EGHA 1K7HA 1ALIA 1P49A 4N7TA 4UOPA 3BDGA 2XRGA 3ED4A 2W5TA 4FDJA 4LRAA 5AJ9A 1EW8A 1HDHA 3IGYB 4GTYA 1B8JA 4LR2A 4LRCA 4UPLA 5IJSA 5L0BA 4NWXA 2GSOA 3NKPA 3NVLA 1ELYA 1HQAA 1ELZA 1HJKA 2W8SA 4UPHA 5LRMA 5L0EA 2W8DA 4TN0A 3B5QA 3IGZB 3A52A 1AUKA 3DYCA 3T01A 4UPIA 1KHLA 4ZG9A 3SZYA 1E2SP 4CXUA 5LQQA 4NWJA 5KXAA 3T00A 4GTWA 5K4PA 4ZGAA 3WBHA 3WAXA 1ED8A 1ZEBA 5GRRA 1ANIA 1URAA 3NKQA 2RH6A 2IUCB 4UPKA 4KAVA 3OT9A 1KHJA 3M8YA 1ANJA 1URBA 5IJQA 4FDIA 3KD8A 4MIVA 5C66A 1AJBA 5DLTA 1ZEDA 4LRBA 2IUCA 3T02A 3NKMA 4MY4A 2VQRA 5DLWA 2D1GA 1ALHA 1E3CP 1FSUA 4KAYA 2XR9A 5EGEA 4GTZA 3BDHA 1EJJA 2W5QA 1KH5A 1AJCA 5LIAA 1KHNA 3TWZA 2W5RA 1KH7A 3IDDA 3UNYA 3UO0A 4KJGA 4KJDA 4LR8A 3M8WA 3LXQA 2GA3A 4CXKA 3WAVA 2W5SA 2X98A 3WAYA 1KH9A 3UN5A 2ZKTA 3DPCA 1ELXA 3CMRA 4QAXA 4ZG6A 5DLVA 4ZG7A 3UN2A 1E1ZP 1ALKA 5L0KA 3M7VA 3TX0A 2GSUA 2GLQA 5INHA 3BDGB 2QZUA 4UOOA 1AJDA 1Y7AA 3NKRA 1EI6A 4MHXA 5HRTA 1Y6VA 3MK0A 3NKOA 1ALJA 3WAWA 4B56A 1AJAA 1O98A 1ZEFA 2GSNA 2W5XA 1O99A 2IFYA 4GTXA 3MK2A 3Q3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LR9 A;  1ED9 A;  1SHQ A;  5TJ3 A;  1KH4 A;  4CYS A;  1N2K A;  4LRE A;  3BDF A;  1EW9 A;  3TG0 A;  1EW2 A;  2ANH A;  4LRD A;  5GOV A;  4YR1 A;  3MK1 A;  1N2L A;  3M8Z A;  1KHK A;  3NKN A;  1SHN A;  4LRF A;  1EQJ A;  3SZZ A;  4UOR A;  5LRN A;  4LR7 A;  3E2D A;  3UN3 A;  4CYR A;  2W5V A;  4KM4 A;  2G9Y A;  1E33 P;  4CXS A;  2W5W A;  4LQY A;  5EGH A;  1K7H A;  1ALI A;  1P49 A;  4N7T A;  4UOP A;  3BDG A;  2XRG A;  3ED4 A;  2W5T A;  4FDJ A;  4LRA A;  5AJ9 A;  1EW8 A;  1HDH A;  3IGY B;  4GTY A;  1B8J A;  4LR2 A;  4LRC A;  4UPL A;  5IJS A;  5L0B A;  4NWX A;  2GSO A;  3NKP A;  3NVL A;  1ELY A;  1HQA A;  1ELZ A;  1HJK A;  2W8S A;  4UPH A;  5LRM A;  5L0E A;  2W8D A;  4TN0 A;  3B5Q A;  3IGZ B;  3A52 A;  1AUK A;  3DYC A;  3T01 A;  4UPI A;  1KHL A;  4ZG9 A;  3SZY A;  1E2S P;  4CXU A;  5LQQ A;  4NWJ A;  5KXA A;  3T00 A;  4GTW A;  5K4P A;  4ZGA A;  3WBH A;  3WAX A;  1ED8 A;  1ZEB A;  5GRR A;  1ANI A;  1URA A;  3NKQ A;  2RH6 A;  2IUC B;  4UPK A;  4KAV A;  3OT9 A;  1KHJ A;  3M8Y A;  1ANJ A;  1URB A;  5IJQ A;  4FDI A;  3KD8 A;  4MIV A;  5C66 A;  1AJB A;  5DLT A;  1ZED A;  4LRB A;  2IUC A;  3T02 A;  3NKM A;  4MY4 A;  2VQR A;  5DLW A;  2D1G A;  1ALH A;  1E3C P;  1FSU A;  4KAY A;  2XR9 A;  5EGE A;  4GTZ A;  3BDH A;  1EJJ A;  2W5Q A;  1KH5 A;  1AJC A;  5LIA A;  1KHN A;  3TWZ A;  2W5R A;  1KH7 A;  3IDD A;  3UNY A;  3UO0 A;  4KJG A;  4KJD A;  4LR8 A;  3M8W A;  3LXQ A;  2GA3 A;  4CXK A;  3WAV A;  2W5S A;  2X98 A;  3WAY A;  1KH9 A;  3UN5 A;  2ZKT A;  3DPC A;  1ELX A;  3CMR A;  4QAX A;  4ZG6 A;  5DLV A;  4ZG7 A;  3UN2 A;  1E1Z P;  1ALK A;  5L0K A;  3M7V A;  3TX0 A;  2GSU A;  2GLQ A;  5INH A;  3BDG B;  2QZU A;  4UOO A;  1AJD A;  1Y7A A;  3NKR A;  1EI6 A;  4MHX A;  5HRT A;  1Y6V A;  3MK0 A;  3NKO A;  1ALJ A;  3WAW A;  4B56 A;  1AJA A;  1O98 A;  1ZEF A;  2GSN A;  2W5X A;  1O99 A;  2IFY A;  4GTX A;  3MK2 A;  3Q3Q A; 
#chains in the Genus database with same CATH topology
 4LR9 A;  1ED9 A;  1SHQ A;  5TJ3 A;  1KH4 A;  4CYS A;  1N2K A;  4LRE A;  3BDF A;  1EW9 A;  3TG0 A;  1EW2 A;  2ANH A;  4LRD A;  5GOV A;  4YR1 A;  3MK1 A;  1N2L A;  3M8Z A;  1KHK A;  3NKN A;  1SHN A;  4LRF A;  1EQJ A;  3SZZ A;  4UOR A;  5LRN A;  4LR7 A;  3E2D A;  3UN3 A;  4CYR A;  2W5V A;  4KM4 A;  2G9Y A;  1E33 P;  4CXS A;  2W5W A;  4LQY A;  5EGH A;  1K7H A;  1ALI A;  1P49 A;  4N7T A;  4UOP A;  3BDG A;  2XRG A;  3ED4 A;  2W5T A;  4FDJ A;  4LRA A;  5AJ9 A;  1EW8 A;  1HDH A;  3IGY B;  4GTY A;  1B8J A;  4LR2 A;  4LRC A;  4UPL A;  5IJS A;  5L0B A;  4NWX A;  2GSO A;  3NKP A;  3NVL A;  1ELY A;  1HQA A;  1ELZ A;  1HJK A;  2W8S A;  4UPH A;  5LRM A;  5L0E A;  2W8D A;  4TN0 A;  3B5Q A;  3IGZ B;  3A52 A;  1AUK A;  3DYC A;  3T01 A;  4UPI A;  1KHL A;  4ZG9 A;  3SZY A;  1E2S P;  4CXU A;  5LQQ A;  4NWJ A;  5KXA A;  3T00 A;  4GTW A;  5K4P A;  4ZGA A;  3WBH A;  3WAX A;  1ED8 A;  1ZEB A;  5GRR A;  1ANI A;  1URA A;  3NKQ A;  2RH6 A;  2IUC B;  4UPK A;  4KAV A;  3OT9 A;  1KHJ A;  3M8Y A;  1ANJ A;  1URB A;  5IJQ A;  4FDI A;  3KD8 A;  4MIV A;  5C66 A;  1AJB A;  5DLT A;  1ZED A;  4LRB A;  2IUC A;  3T02 A;  3NKM A;  4MY4 A;  2VQR A;  5DLW A;  2D1G A;  1ALH A;  1E3C P;  1FSU A;  4KAY A;  2XR9 A;  5EGE A;  4GTZ A;  3BDH A;  1EJJ A;  2W5Q A;  1KH5 A;  1AJC A;  5LIA A;  1KHN A;  3TWZ A;  2W5R A;  1KH7 A;  3IDD A;  3UNY A;  3UO0 A;  4KJG A;  4KJD A;  4LR8 A;  3M8W A;  3LXQ A;  2GA3 A;  4CXK A;  3WAV A;  2W5S A;  2X98 A;  3WAY A;  1KH9 A;  3UN5 A;  2ZKT A;  3DPC A;  1ELX A;  3CMR A;  4QAX A;  4ZG6 A;  5DLV A;  4ZG7 A;  3UN2 A;  1E1Z P;  1ALK A;  5L0K A;  3M7V A;  3TX0 A;  2GSU A;  2GLQ A;  5INH A;  3BDG B;  2QZU A;  4UOO A;  1AJD A;  1Y7A A;  3NKR A;  1EI6 A;  4MHX A;  5HRT A;  1Y6V A;  3MK0 A;  3NKO A;  1ALJ A;  3WAW A;  4B56 A;  1AJA A;  1O98 A;  1ZEF A;  2GSN A;  2W5X A;  1O99 A;  2IFY A;  4GTX A;  3MK2 A;  3Q3Q A; 
#chains in the Genus database with same CATH homology
 4LR9 A;  1ED9 A;  1SHQ A;  5TJ3 A;  1KH4 A;  4CYS A;  1N2K A;  4LRE A;  3BDF A;  1EW9 A;  3TG0 A;  1EW2 A;  2ANH A;  4LRD A;  5GOV A;  4YR1 A;  3MK1 A;  1N2L A;  3M8Z A;  1KHK A;  3NKN A;  1SHN A;  4LRF A;  1EQJ A;  3SZZ A;  4UOR A;  5LRN A;  4LR7 A;  3E2D A;  3UN3 A;  4CYR A;  2W5V A;  4KM4 A;  2G9Y A;  1E33 P;  4CXS A;  2W5W A;  4LQY A;  5EGH A;  1K7H A;  1ALI A;  1P49 A;  4N7T A;  4UOP A;  3BDG A;  2XRG A;  3ED4 A;  2W5T A;  4FDJ A;  4LRA A;  5AJ9 A;  1EW8 A;  1HDH A;  3IGY B;  4GTY A;  1B8J A;  4LR2 A;  4LRC A;  4UPL A;  5IJS A;  5L0B A;  4NWX A;  2GSO A;  3NKP A;  3NVL A;  1ELY A;  1HQA A;  1ELZ A;  1HJK A;  2W8S A;  4UPH A;  5LRM A;  5L0E A;  2W8D A;  4TN0 A;  3B5Q A;  3IGZ B;  3A52 A;  1AUK A;  3DYC A;  3T01 A;  4UPI A;  1KHL A;  4ZG9 A;  3SZY A;  1E2S P;  4CXU A;  5LQQ A;  4NWJ A;  5KXA A;  3T00 A;  4GTW A;  5K4P A;  4ZGA A;  3WBH A;  3WAX A;  1ED8 A;  1ZEB A;  5GRR A;  1ANI A;  1URA A;  3NKQ A;  2RH6 A;  2IUC B;  4UPK A;  4KAV A;  3OT9 A;  1KHJ A;  3M8Y A;  1ANJ A;  1URB A;  5IJQ A;  4FDI A;  3KD8 A;  4MIV A;  5C66 A;  1AJB A;  5DLT A;  1ZED A;  4LRB A;  2IUC A;  3T02 A;  3NKM A;  4MY4 A;  2VQR A;  5DLW A;  2D1G A;  1ALH A;  1E3C P;  1FSU A;  4KAY A;  2XR9 A;  5EGE A;  4GTZ A;  3BDH A;  1EJJ A;  2W5Q A;  1KH5 A;  1AJC A;  5LIA A;  1KHN A;  3TWZ A;  2W5R A;  1KH7 A;  3IDD A;  3UNY A;  3UO0 A;  4KJG A;  4KJD A;  4LR8 A;  3M8W A;  3LXQ A;  2GA3 A;  4CXK A;  3WAV A;  2W5S A;  2X98 A;  3WAY A;  1KH9 A;  3UN5 A;  2ZKT A;  3DPC A;  1ELX A;  3CMR A;  4QAX A;  4ZG6 A;  5DLV A;  4ZG7 A;  3UN2 A;  1E1Z P;  1ALK A;  5L0K A;  3M7V A;  3TX0 A;  2GSU A;  2GLQ A;  5INH A;  3BDG B;  2QZU A;  4UOO A;  1AJD A;  1Y7A A;  3NKR A;  1EI6 A;  4MHX A;  5HRT A;  1Y6V A;  3MK0 A;  3NKO A;  1ALJ A;  3WAW A;  4B56 A;  1AJA A;  1O98 A;  1ZEF A;  2GSN A;  2W5X A;  1O99 A;  2IFY A;  4GTX A;  3MK2 A;  3Q3Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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