4KJDA

Ratintestinal ap expressed in e. coli
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
Knots found
sequence length
478
structure length
407
Chain Sequence
VEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVTLRHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Intestinal-type alkaline phosphatase 1
total genus 148
structure length 407
sequence length 478
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2013-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4kjdA00
4LR9A 4KAVA 1E2SP 3NVLA 5TJ3A 3BDHA 1EI6A 1E3CP 1Y6VA 3M8ZA 1O99A 5DLWA 2IUCA 1KH4A 1URAA 3UNYA 4CXSA 2IUCB 3OT9A 3WAVA 4YR1A 1EQJA 2W5WA 3T01A 3TX0A 5LIAA 1ZEFA 3IDDA 4KAYA 4UPKA 2XR9A 1KH5A 2W5SA 1KHLA 4KM4A 1AJDA 4CYRA 2GSOA 1P49A 4LRBA 4MY4A 1ELXA 3DYCA 3M7VA 1HDHA 4UOPA 3UN5A 5AJ9A 2W5QA 2GLQA 1AJCA 1E1ZP 5KXAA 3M8WA 3NKQA 5LRMA 1HQAA 1K7HA 2GSNA 4KJGA 1ANJA 4N7TA 5IJSA 3WAWA 2RH6A 2W5VA 5EGEA 1N2LA 1EW9A 3T02A 3TG0A 1KHNA 4LR7A 4LR2A 3NKRA 1HJKA 4GTWA 4LR8A 3E2DA 4ZG7A 5IJQA 3A52A 4UPLA 4CXUA 3UN3A 1ALIA 4CYSA 2W5RA 3CMRA 5K4PA 4TN0A 1KHKA 4LQYA 1E33P 4ZG6A 3MK0A 3IGYB 2XRGA 1AUKA 1ELYA 5EGHA 4CXKA 3DPCA 5LQQA 5HRTA 4NWXA 3TWZA 3ED4A 3SZYA 3MK1A 4KJDA 3IGZB 2W5TA 5L0EA 2G9YA 2GSUA 5LRNA 3T00A 3KD8A 3NKPA 4FDJA 3B5QA 1KH9A 2W5XA 4GTYA 1ZEBA 4NWJA 5L0KA 1EJJA 2ANHA 4LRFA 1B8JA 4QAXA 4UORA 4UPIA 5GOVA 4MHXA 2W8SA 3M8YA 4LRDA 3WAXA 1EW8A 5DLTA 4ZG9A 4GTXA 4UOOA 3BDGA 1Y7AA 3BDGB 1ALJA 2W8DA 4MIVA 2QZUA 3UN2A 3MK2A 1ALKA 3SZZA 1ANIA 1SHQA 1KHJA 3NKOA 3NKMA 5DLVA 3UO0A 4UPHA 3NKNA 1KH7A 4GTZA 3Q3QA 1ALHA 1ED8A 4ZGAA 2VQRA 3LXQA 1ZEDA 5C66A 1EW2A 2X98A 1ED9A 1N2KA 1AJBA 4LREA 4LRCA 4LRAA 5INHA 2ZKTA 5L0BA 1O98A 1FSUA 2D1GA 3WBHA 3BDFA 1SHNA 4FDIA 1AJAA 5GRRA 2IFYA 3WAYA 2GA3A 4B56A 1URBA 1ELZA
chains in the Genus database with same CATH superfamily
4LR9A 4KAVA 1E2SP 3NVLA 5TJ3A 3BDHA 1EI6A 1E3CP 1Y6VA 3M8ZA 1O99A 5DLWA 2IUCA 1KH4A 1URAA 3UNYA 4CXSA 2IUCB 3OT9A 3WAVA 4YR1A 1EQJA 2W5WA 3T01A 3TX0A 5LIAA 1ZEFA 3IDDA 4KAYA 4UPKA 2XR9A 1KH5A 2W5SA 1KHLA 4KM4A 1AJDA 4CYRA 2GSOA 1P49A 4LRBA 4MY4A 1ELXA 3DYCA 3M7VA 1HDHA 4UOPA 3UN5A 5AJ9A 2W5QA 2GLQA 1AJCA 1E1ZP 5KXAA 3M8WA 3NKQA 5LRMA 1HQAA 1K7HA 2GSNA 4KJGA 1ANJA 4N7TA 5IJSA 3WAWA 2RH6A 2W5VA 5EGEA 1N2LA 1EW9A 3T02A 3TG0A 1KHNA 4LR7A 4LR2A 3NKRA 1HJKA 4GTWA 4LR8A 3E2DA 4ZG7A 5IJQA 3A52A 4UPLA 4CXUA 3UN3A 1ALIA 4CYSA 2W5RA 3CMRA 5K4PA 4TN0A 1KHKA 4LQYA 1E33P 4ZG6A 3MK0A 3IGYB 2XRGA 1AUKA 1ELYA 5EGHA 4CXKA 3DPCA 5LQQA 5HRTA 4NWXA 3TWZA 3ED4A 3SZYA 3MK1A 4KJDA 3IGZB 2W5TA 5L0EA 2G9YA 2GSUA 5LRNA 3T00A 3KD8A 3NKPA 4FDJA 3B5QA 1KH9A 2W5XA 4GTYA 1ZEBA 4NWJA 5L0KA 1EJJA 2ANHA 4LRFA 1B8JA 4QAXA 4UORA 4UPIA 5GOVA 4MHXA 2W8SA 3M8YA 4LRDA 3WAXA 1EW8A 5DLTA 4ZG9A 4GTXA 4UOOA 3BDGA 1Y7AA 3BDGB 1ALJA 2W8DA 4MIVA 2QZUA 3UN2A 3MK2A 1ALKA 3SZZA 1ANIA 1SHQA 1KHJA 3NKOA 3NKMA 5DLVA 3UO0A 4UPHA 3NKNA 1KH7A 4GTZA 3Q3QA 1ALHA 1ED8A 4ZGAA 2VQRA 3LXQA 1ZEDA 5C66A 1EW2A 2X98A 1ED9A 1N2KA 1AJBA 4LREA 4LRCA 4LRAA 5INHA 2ZKTA 5L0BA 1O98A 1FSUA 2D1GA 3WBHA 3BDFA 1SHNA 4FDIA 1AJAA 5GRRA 2IFYA 3WAYA 2GA3A 4B56A 1URBA 1ELZA
chains in the Genus database with same CATH topology
4LR9A 4KAVA 1E2SP 3NVLA 5TJ3A 3BDHA 1EI6A 1E3CP 1Y6VA 3M8ZA 1O99A 5DLWA 2IUCA 1KH4A 1URAA 3UNYA 4CXSA 2IUCB 3OT9A 3WAVA 4YR1A 1EQJA 2W5WA 3T01A 3TX0A 5LIAA 1ZEFA 3IDDA 4KAYA 4UPKA 2XR9A 1KH5A 2W5SA 1KHLA 4KM4A 1AJDA 4CYRA 2GSOA 1P49A 4LRBA 4MY4A 1ELXA 3DYCA 3M7VA 1HDHA 4UOPA 3UN5A 5AJ9A 2W5QA 2GLQA 1AJCA 1E1ZP 5KXAA 3M8WA 3NKQA 5LRMA 1HQAA 1K7HA 2GSNA 4KJGA 1ANJA 4N7TA 5IJSA 3WAWA 2RH6A 2W5VA 5EGEA 1N2LA 1EW9A 3T02A 3TG0A 1KHNA 4LR7A 4LR2A 3NKRA 1HJKA 4GTWA 4LR8A 3E2DA 4ZG7A 5IJQA 3A52A 4UPLA 4CXUA 3UN3A 1ALIA 4CYSA 2W5RA 3CMRA 5K4PA 4TN0A 1KHKA 4LQYA 1E33P 4ZG6A 3MK0A 3IGYB 2XRGA 1AUKA 1ELYA 5EGHA 4CXKA 3DPCA 5LQQA 5HRTA 4NWXA 3TWZA 3ED4A 3SZYA 3MK1A 4KJDA 3IGZB 2W5TA 5L0EA 2G9YA 2GSUA 5LRNA 3T00A 3KD8A 3NKPA 4FDJA 3B5QA 1KH9A 2W5XA 4GTYA 1ZEBA 4NWJA 5L0KA 1EJJA 2ANHA 4LRFA 1B8JA 4QAXA 4UORA 4UPIA 5GOVA 4MHXA 2W8SA 3M8YA 4LRDA 3WAXA 1EW8A 5DLTA 4ZG9A 4GTXA 4UOOA 3BDGA 1Y7AA 3BDGB 1ALJA 2W8DA 4MIVA 2QZUA 3UN2A 3MK2A 1ALKA 3SZZA 1ANIA 1SHQA 1KHJA 3NKOA 3NKMA 5DLVA 3UO0A 4UPHA 3NKNA 1KH7A 4GTZA 3Q3QA 1ALHA 1ED8A 4ZGAA 2VQRA 3LXQA 1ZEDA 5C66A 1EW2A 2X98A 1ED9A 1N2KA 1AJBA 4LREA 4LRCA 4LRAA 5INHA 2ZKTA 5L0BA 1O98A 1FSUA 2D1GA 3WBHA 3BDFA 1SHNA 4FDIA 1AJAA 5GRRA 2IFYA 3WAYA 2GA3A 4B56A 1URBA 1ELZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LR9 A;  4KAV A;  1E2S P;  3NVL A;  5TJ3 A;  3BDH A;  1EI6 A;  1E3C P;  1Y6V A;  3M8Z A;  1O99 A;  5DLW A;  2IUC A;  1KH4 A;  1URA A;  3UNY A;  4CXS A;  2IUC B;  3OT9 A;  3WAV A;  4YR1 A;  1EQJ A;  2W5W A;  3T01 A;  3TX0 A;  5LIA A;  1ZEF A;  3IDD A;  4KAY A;  4UPK A;  2XR9 A;  1KH5 A;  2W5S A;  1KHL A;  4KM4 A;  1AJD A;  4CYR A;  2GSO A;  1P49 A;  4LRB A;  4MY4 A;  1ELX A;  3DYC A;  3M7V A;  1HDH A;  4UOP A;  3UN5 A;  5AJ9 A;  2W5Q A;  2GLQ A;  1AJC A;  1E1Z P;  5KXA A;  3M8W A;  3NKQ A;  5LRM A;  1HQA A;  1K7H A;  2GSN A;  4KJG A;  1ANJ A;  4N7T A;  5IJS A;  3WAW A;  2RH6 A;  2W5V A;  5EGE A;  1N2L A;  1EW9 A;  3T02 A;  3TG0 A;  1KHN A;  4LR7 A;  4LR2 A;  3NKR A;  1HJK A;  4GTW A;  4LR8 A;  3E2D A;  4ZG7 A;  5IJQ A;  3A52 A;  4UPL A;  4CXU A;  3UN3 A;  1ALI A;  4CYS A;  2W5R A;  3CMR A;  5K4P A;  4TN0 A;  1KHK A;  4LQY A;  1E33 P;  4ZG6 A;  3MK0 A;  3IGY B;  2XRG A;  1AUK A;  1ELY A;  5EGH A;  4CXK A;  3DPC A;  5LQQ A;  5HRT A;  4NWX A;  3TWZ A;  3ED4 A;  3SZY A;  3MK1 A;  4KJD A;  3IGZ B;  2W5T A;  5L0E A;  2G9Y A;  2GSU A;  5LRN A;  3T00 A;  3KD8 A;  3NKP A;  4FDJ A;  3B5Q A;  1KH9 A;  2W5X A;  4GTY A;  1ZEB A;  4NWJ A;  5L0K A;  1EJJ A;  2ANH A;  4LRF A;  1B8J A;  4QAX A;  4UOR A;  4UPI A;  5GOV A;  4MHX A;  2W8S A;  3M8Y A;  4LRD A;  3WAX A;  1EW8 A;  5DLT A;  4ZG9 A;  4GTX A;  4UOO A;  3BDG A;  1Y7A A;  3BDG B;  1ALJ A;  2W8D A;  4MIV A;  2QZU A;  3UN2 A;  3MK2 A;  1ALK A;  3SZZ A;  1ANI A;  1SHQ A;  1KHJ A;  3NKO A;  3NKM A;  5DLV A;  3UO0 A;  4UPH A;  3NKN A;  1KH7 A;  4GTZ A;  3Q3Q A;  1ALH A;  1ED8 A;  4ZGA A;  2VQR A;  3LXQ A;  1ZED A;  5C66 A;  1EW2 A;  2X98 A;  1ED9 A;  1N2K A;  1AJB A;  4LRE A;  4LRC A;  4LRA A;  5INH A;  2ZKT A;  5L0B A;  1O98 A;  1FSU A;  2D1G A;  3WBH A;  3BDF A;  1SHN A;  4FDI A;  1AJA A;  5GRR A;  2IFY A;  3WAY A;  2GA3 A;  4B56 A;  1URB A;  1ELZ A; 
#chains in the Genus database with same CATH topology
 4LR9 A;  4KAV A;  1E2S P;  3NVL A;  5TJ3 A;  3BDH A;  1EI6 A;  1E3C P;  1Y6V A;  3M8Z A;  1O99 A;  5DLW A;  2IUC A;  1KH4 A;  1URA A;  3UNY A;  4CXS A;  2IUC B;  3OT9 A;  3WAV A;  4YR1 A;  1EQJ A;  2W5W A;  3T01 A;  3TX0 A;  5LIA A;  1ZEF A;  3IDD A;  4KAY A;  4UPK A;  2XR9 A;  1KH5 A;  2W5S A;  1KHL A;  4KM4 A;  1AJD A;  4CYR A;  2GSO A;  1P49 A;  4LRB A;  4MY4 A;  1ELX A;  3DYC A;  3M7V A;  1HDH A;  4UOP A;  3UN5 A;  5AJ9 A;  2W5Q A;  2GLQ A;  1AJC A;  1E1Z P;  5KXA A;  3M8W A;  3NKQ A;  5LRM A;  1HQA A;  1K7H A;  2GSN A;  4KJG A;  1ANJ A;  4N7T A;  5IJS A;  3WAW A;  2RH6 A;  2W5V A;  5EGE A;  1N2L A;  1EW9 A;  3T02 A;  3TG0 A;  1KHN A;  4LR7 A;  4LR2 A;  3NKR A;  1HJK A;  4GTW A;  4LR8 A;  3E2D A;  4ZG7 A;  5IJQ A;  3A52 A;  4UPL A;  4CXU A;  3UN3 A;  1ALI A;  4CYS A;  2W5R A;  3CMR A;  5K4P A;  4TN0 A;  1KHK A;  4LQY A;  1E33 P;  4ZG6 A;  3MK0 A;  3IGY B;  2XRG A;  1AUK A;  1ELY A;  5EGH A;  4CXK A;  3DPC A;  5LQQ A;  5HRT A;  4NWX A;  3TWZ A;  3ED4 A;  3SZY A;  3MK1 A;  4KJD A;  3IGZ B;  2W5T A;  5L0E A;  2G9Y A;  2GSU A;  5LRN A;  3T00 A;  3KD8 A;  3NKP A;  4FDJ A;  3B5Q A;  1KH9 A;  2W5X A;  4GTY A;  1ZEB A;  4NWJ A;  5L0K A;  1EJJ A;  2ANH A;  4LRF A;  1B8J A;  4QAX A;  4UOR A;  4UPI A;  5GOV A;  4MHX A;  2W8S A;  3M8Y A;  4LRD A;  3WAX A;  1EW8 A;  5DLT A;  4ZG9 A;  4GTX A;  4UOO A;  3BDG A;  1Y7A A;  3BDG B;  1ALJ A;  2W8D A;  4MIV A;  2QZU A;  3UN2 A;  3MK2 A;  1ALK A;  3SZZ A;  1ANI A;  1SHQ A;  1KHJ A;  3NKO A;  3NKM A;  5DLV A;  3UO0 A;  4UPH A;  3NKN A;  1KH7 A;  4GTZ A;  3Q3Q A;  1ALH A;  1ED8 A;  4ZGA A;  2VQR A;  3LXQ A;  1ZED A;  5C66 A;  1EW2 A;  2X98 A;  1ED9 A;  1N2K A;  1AJB A;  4LRE A;  4LRC A;  4LRA A;  5INH A;  2ZKT A;  5L0B A;  1O98 A;  1FSU A;  2D1G A;  3WBH A;  3BDF A;  1SHN A;  4FDI A;  1AJA A;  5GRR A;  2IFY A;  3WAY A;  2GA3 A;  4B56 A;  1URB A;  1ELZ A; 
#chains in the Genus database with same CATH homology
 4LR9 A;  4KAV A;  1E2S P;  3NVL A;  5TJ3 A;  3BDH A;  1EI6 A;  1E3C P;  1Y6V A;  3M8Z A;  1O99 A;  5DLW A;  2IUC A;  1KH4 A;  1URA A;  3UNY A;  4CXS A;  2IUC B;  3OT9 A;  3WAV A;  4YR1 A;  1EQJ A;  2W5W A;  3T01 A;  3TX0 A;  5LIA A;  1ZEF A;  3IDD A;  4KAY A;  4UPK A;  2XR9 A;  1KH5 A;  2W5S A;  1KHL A;  4KM4 A;  1AJD A;  4CYR A;  2GSO A;  1P49 A;  4LRB A;  4MY4 A;  1ELX A;  3DYC A;  3M7V A;  1HDH A;  4UOP A;  3UN5 A;  5AJ9 A;  2W5Q A;  2GLQ A;  1AJC A;  1E1Z P;  5KXA A;  3M8W A;  3NKQ A;  5LRM A;  1HQA A;  1K7H A;  2GSN A;  4KJG A;  1ANJ A;  4N7T A;  5IJS A;  3WAW A;  2RH6 A;  2W5V A;  5EGE A;  1N2L A;  1EW9 A;  3T02 A;  3TG0 A;  1KHN A;  4LR7 A;  4LR2 A;  3NKR A;  1HJK A;  4GTW A;  4LR8 A;  3E2D A;  4ZG7 A;  5IJQ A;  3A52 A;  4UPL A;  4CXU A;  3UN3 A;  1ALI A;  4CYS A;  2W5R A;  3CMR A;  5K4P A;  4TN0 A;  1KHK A;  4LQY A;  1E33 P;  4ZG6 A;  3MK0 A;  3IGY B;  2XRG A;  1AUK A;  1ELY A;  5EGH A;  4CXK A;  3DPC A;  5LQQ A;  5HRT A;  4NWX A;  3TWZ A;  3ED4 A;  3SZY A;  3MK1 A;  4KJD A;  3IGZ B;  2W5T A;  5L0E A;  2G9Y A;  2GSU A;  5LRN A;  3T00 A;  3KD8 A;  3NKP A;  4FDJ A;  3B5Q A;  1KH9 A;  2W5X A;  4GTY A;  1ZEB A;  4NWJ A;  5L0K A;  1EJJ A;  2ANH A;  4LRF A;  1B8J A;  4QAX A;  4UOR A;  4UPI A;  5GOV A;  4MHX A;  2W8S A;  3M8Y A;  4LRD A;  3WAX A;  1EW8 A;  5DLT A;  4ZG9 A;  4GTX A;  4UOO A;  3BDG A;  1Y7A A;  3BDG B;  1ALJ A;  2W8D A;  4MIV A;  2QZU A;  3UN2 A;  3MK2 A;  1ALK A;  3SZZ A;  1ANI A;  1SHQ A;  1KHJ A;  3NKO A;  3NKM A;  5DLV A;  3UO0 A;  4UPH A;  3NKN A;  1KH7 A;  4GTZ A;  3Q3Q A;  1ALH A;  1ED8 A;  4ZGA A;  2VQR A;  3LXQ A;  1ZED A;  5C66 A;  1EW2 A;  2X98 A;  1ED9 A;  1N2K A;  1AJB A;  4LRE A;  4LRC A;  4LRA A;  5INH A;  2ZKT A;  5L0B A;  1O98 A;  1FSU A;  2D1G A;  3WBH A;  3BDF A;  1SHN A;  4FDI A;  1AJA A;  5GRR A;  2IFY A;  3WAY A;  2GA3 A;  4B56 A;  1URB A;  1ELZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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