4KJDA

Ratintestinal ap expressed in e. coli
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
Knots found
sequence length
478
structure length
407
Chain Sequence
VEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVTLRHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Intestinal-type alkaline phosphatase 1
total genus 148
structure length 407
sequence length 478
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2013-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4kjdA00
1ANJA 2ZKTA 4UPHA 3E2DA 5GRRA 3M7VA 3TWZA 3SZZA 1KH7A 1ALJA 3MK1A 1N2KA 3SZYA 2D1GA 3NKOA 1SHQA 3NKMA 1ELYA 1EW2A 1E1ZP 2VQRA 4KAYA 4LRDA 3T02A 3A52A 5L0KA 1EW9A 4KJGA 4MY4A 3NKNA 4UORA 5EGEA 4KJDA 3WAVA 3UN5A 4NWJA 2XR9A 1KH5A 3NKPA 5K4PA 1ANIA 1K7HA 4LR9A 5KXAA 4LR7A 4CYRA 3OT9A 4LRAA 1EJJA 5AJ9A 1FSUA 4GTXA 1KHJA 4MHXA 1E33P 2W8DA 4NWXA 2W5TA 4CXKA 1Y7AA 3B5QA 1ELXA 2W8SA 4GTZA 1URAA 2IUCB 3T01A 1P49A 4MIVA 4KM4A 3BDGA 1EI6A 3NVLA 4ZG6A 5DLVA 3IDDA 2GSNA 2W5XA 2IFYA 5DLWA 4FDJA 3ED4A 1ZEBA 5LIAA 3UN2A 2GSOA 1ALHA 4GTWA 4GTYA 5LRMA 4ZG7A 1AJAA 3WBHA 4UOOA 3DPCA 3UNYA 5LQQA 5TJ3A 3WAXA 1KH4A 3M8YA 4QAXA 1KHLA 4N7TA 1E3CP 4LRBA 3UO0A 5C66A 3LXQA 5HRTA 1SHNA 1HQAA 2GLQA 4ZG9A 4LR8A 3DYCA 1AJCA 1URBA 2G9YA 1Y6VA 3Q3QA 4CXSA 1HDHA 1O98A 4CXUA 1ED9A 2GA3A 1B8JA 4LRFA 4TN0A 3MK0A 1KH9A 4CYSA 4KAVA 1N2LA 4LRCA 5L0EA 5L0BA 1O99A 5IJQA 5DLTA 2X98A 2QZUA 3NKQA 4ZGAA 1AUKA 1ALKA 3BDHA 1ED8A 3T00A 4LQYA 3IGYB 3M8ZA 1HJKA 2W5WA 4UPLA 3TX0A 3WAYA 2W5VA 3NKRA 2ANHA 4FDIA 2IUCA 1EQJA 2W5QA 2XRGA 1ZEDA 3WAWA 1AJBA 4YR1A 5LRNA 1ALIA 3TG0A 1KHNA 3MK2A 4B56A 1ZEFA 3KD8A 4UPIA 3CMRA 2GSUA 2W5SA 3BDFA 3BDGB 3IGZB 4UOPA 2RH6A 1KHKA 4LR2A 5IJSA 5INHA 4LREA 4UPKA 1EW8A 2W5RA 3M8WA 5GOVA 5EGHA 1E2SP 3UN3A 1AJDA 1ELZA
chains in the Genus database with same CATH superfamily
1ANJA 2ZKTA 4UPHA 3E2DA 5GRRA 3M7VA 3TWZA 3SZZA 1KH7A 1ALJA 3MK1A 1N2KA 3SZYA 2D1GA 3NKOA 1SHQA 3NKMA 1ELYA 1EW2A 1E1ZP 2VQRA 4KAYA 4LRDA 3T02A 3A52A 5L0KA 1EW9A 4KJGA 4MY4A 3NKNA 4UORA 5EGEA 4KJDA 3WAVA 3UN5A 4NWJA 2XR9A 1KH5A 3NKPA 5K4PA 1ANIA 1K7HA 4LR9A 5KXAA 4LR7A 4CYRA 3OT9A 4LRAA 1EJJA 5AJ9A 1FSUA 4GTXA 1KHJA 4MHXA 1E33P 2W8DA 4NWXA 2W5TA 4CXKA 1Y7AA 3B5QA 1ELXA 2W8SA 4GTZA 1URAA 2IUCB 3T01A 1P49A 4MIVA 4KM4A 3BDGA 1EI6A 3NVLA 4ZG6A 5DLVA 3IDDA 2GSNA 2W5XA 2IFYA 5DLWA 4FDJA 3ED4A 1ZEBA 5LIAA 3UN2A 2GSOA 1ALHA 4GTWA 4GTYA 5LRMA 4ZG7A 1AJAA 3WBHA 4UOOA 3DPCA 3UNYA 5LQQA 5TJ3A 3WAXA 1KH4A 3M8YA 4QAXA 1KHLA 4N7TA 1E3CP 4LRBA 3UO0A 5C66A 3LXQA 5HRTA 1SHNA 1HQAA 2GLQA 4ZG9A 4LR8A 3DYCA 1AJCA 1URBA 2G9YA 1Y6VA 3Q3QA 4CXSA 1HDHA 1O98A 4CXUA 1ED9A 2GA3A 1B8JA 4LRFA 4TN0A 3MK0A 1KH9A 4CYSA 4KAVA 1N2LA 4LRCA 5L0EA 5L0BA 1O99A 5IJQA 5DLTA 2X98A 2QZUA 3NKQA 4ZGAA 1AUKA 1ALKA 3BDHA 1ED8A 3T00A 4LQYA 3IGYB 3M8ZA 1HJKA 2W5WA 4UPLA 3TX0A 3WAYA 2W5VA 3NKRA 2ANHA 4FDIA 2IUCA 1EQJA 2W5QA 2XRGA 1ZEDA 3WAWA 1AJBA 4YR1A 5LRNA 1ALIA 3TG0A 1KHNA 3MK2A 4B56A 1ZEFA 3KD8A 4UPIA 3CMRA 2GSUA 2W5SA 3BDFA 3BDGB 3IGZB 4UOPA 2RH6A 1KHKA 4LR2A 5IJSA 5INHA 4LREA 4UPKA 1EW8A 2W5RA 3M8WA 5GOVA 5EGHA 1E2SP 3UN3A 1AJDA 1ELZA
chains in the Genus database with same CATH topology
1ANJA 2ZKTA 4UPHA 3E2DA 5GRRA 3M7VA 3TWZA 3SZZA 1KH7A 1ALJA 3MK1A 1N2KA 3SZYA 2D1GA 3NKOA 1SHQA 3NKMA 1ELYA 1EW2A 1E1ZP 2VQRA 4KAYA 4LRDA 3T02A 3A52A 5L0KA 1EW9A 4KJGA 4MY4A 3NKNA 4UORA 5EGEA 4KJDA 3WAVA 3UN5A 4NWJA 2XR9A 1KH5A 3NKPA 5K4PA 1ANIA 1K7HA 4LR9A 5KXAA 4LR7A 4CYRA 3OT9A 4LRAA 1EJJA 5AJ9A 1FSUA 4GTXA 1KHJA 4MHXA 1E33P 2W8DA 4NWXA 2W5TA 4CXKA 1Y7AA 3B5QA 1ELXA 2W8SA 4GTZA 1URAA 2IUCB 3T01A 1P49A 4MIVA 4KM4A 3BDGA 1EI6A 3NVLA 4ZG6A 5DLVA 3IDDA 2GSNA 2W5XA 2IFYA 5DLWA 4FDJA 3ED4A 1ZEBA 5LIAA 3UN2A 2GSOA 1ALHA 4GTWA 4GTYA 5LRMA 4ZG7A 1AJAA 3WBHA 4UOOA 3DPCA 3UNYA 5LQQA 5TJ3A 3WAXA 1KH4A 3M8YA 4QAXA 1KHLA 4N7TA 1E3CP 4LRBA 3UO0A 5C66A 3LXQA 5HRTA 1SHNA 1HQAA 2GLQA 4ZG9A 4LR8A 3DYCA 1AJCA 1URBA 2G9YA 1Y6VA 3Q3QA 4CXSA 1HDHA 1O98A 4CXUA 1ED9A 2GA3A 1B8JA 4LRFA 4TN0A 3MK0A 1KH9A 4CYSA 4KAVA 1N2LA 4LRCA 5L0EA 5L0BA 1O99A 5IJQA 5DLTA 2X98A 2QZUA 3NKQA 4ZGAA 1AUKA 1ALKA 3BDHA 1ED8A 3T00A 4LQYA 3IGYB 3M8ZA 1HJKA 2W5WA 4UPLA 3TX0A 3WAYA 2W5VA 3NKRA 2ANHA 4FDIA 2IUCA 1EQJA 2W5QA 2XRGA 1ZEDA 3WAWA 1AJBA 4YR1A 5LRNA 1ALIA 3TG0A 1KHNA 3MK2A 4B56A 1ZEFA 3KD8A 4UPIA 3CMRA 2GSUA 2W5SA 3BDFA 3BDGB 3IGZB 4UOPA 2RH6A 1KHKA 4LR2A 5IJSA 5INHA 4LREA 4UPKA 1EW8A 2W5RA 3M8WA 5GOVA 5EGHA 1E2SP 3UN3A 1AJDA 1ELZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ANJ A;  2ZKT A;  4UPH A;  3E2D A;  5GRR A;  3M7V A;  3TWZ A;  3SZZ A;  1KH7 A;  1ALJ A;  3MK1 A;  1N2K A;  3SZY A;  2D1G A;  3NKO A;  1SHQ A;  3NKM A;  1ELY A;  1EW2 A;  1E1Z P;  2VQR A;  4KAY A;  4LRD A;  3T02 A;  3A52 A;  5L0K A;  1EW9 A;  4KJG A;  4MY4 A;  3NKN A;  4UOR A;  5EGE A;  4KJD A;  3WAV A;  3UN5 A;  4NWJ A;  2XR9 A;  1KH5 A;  3NKP A;  5K4P A;  1ANI A;  1K7H A;  4LR9 A;  5KXA A;  4LR7 A;  4CYR A;  3OT9 A;  4LRA A;  1EJJ A;  5AJ9 A;  1FSU A;  4GTX A;  1KHJ A;  4MHX A;  1E33 P;  2W8D A;  4NWX A;  2W5T A;  4CXK A;  1Y7A A;  3B5Q A;  1ELX A;  2W8S A;  4GTZ A;  1URA A;  2IUC B;  3T01 A;  1P49 A;  4MIV A;  4KM4 A;  3BDG A;  1EI6 A;  3NVL A;  4ZG6 A;  5DLV A;  3IDD A;  2GSN A;  2W5X A;  2IFY A;  5DLW A;  4FDJ A;  3ED4 A;  1ZEB A;  5LIA A;  3UN2 A;  2GSO A;  1ALH A;  4GTW A;  4GTY A;  5LRM A;  4ZG7 A;  1AJA A;  3WBH A;  4UOO A;  3DPC A;  3UNY A;  5LQQ A;  5TJ3 A;  3WAX A;  1KH4 A;  3M8Y A;  4QAX A;  1KHL A;  4N7T A;  1E3C P;  4LRB A;  3UO0 A;  5C66 A;  3LXQ A;  5HRT A;  1SHN A;  1HQA A;  2GLQ A;  4ZG9 A;  4LR8 A;  3DYC A;  1AJC A;  1URB A;  2G9Y A;  1Y6V A;  3Q3Q A;  4CXS A;  1HDH A;  1O98 A;  4CXU A;  1ED9 A;  2GA3 A;  1B8J A;  4LRF A;  4TN0 A;  3MK0 A;  1KH9 A;  4CYS A;  4KAV A;  1N2L A;  4LRC A;  5L0E A;  5L0B A;  1O99 A;  5IJQ A;  5DLT A;  2X98 A;  2QZU A;  3NKQ A;  4ZGA A;  1AUK A;  1ALK A;  3BDH A;  1ED8 A;  3T00 A;  4LQY A;  3IGY B;  3M8Z A;  1HJK A;  2W5W A;  4UPL A;  3TX0 A;  3WAY A;  2W5V A;  3NKR A;  2ANH A;  4FDI A;  2IUC A;  1EQJ A;  2W5Q A;  2XRG A;  1ZED A;  3WAW A;  1AJB A;  4YR1 A;  5LRN A;  1ALI A;  3TG0 A;  1KHN A;  3MK2 A;  4B56 A;  1ZEF A;  3KD8 A;  4UPI A;  3CMR A;  2GSU A;  2W5S A;  3BDF A;  3BDG B;  3IGZ B;  4UOP A;  2RH6 A;  1KHK A;  4LR2 A;  5IJS A;  5INH A;  4LRE A;  4UPK A;  1EW8 A;  2W5R A;  3M8W A;  5GOV A;  5EGH A;  1E2S P;  3UN3 A;  1AJD A;  1ELZ A; 
#chains in the Genus database with same CATH topology
 1ANJ A;  2ZKT A;  4UPH A;  3E2D A;  5GRR A;  3M7V A;  3TWZ A;  3SZZ A;  1KH7 A;  1ALJ A;  3MK1 A;  1N2K A;  3SZY A;  2D1G A;  3NKO A;  1SHQ A;  3NKM A;  1ELY A;  1EW2 A;  1E1Z P;  2VQR A;  4KAY A;  4LRD A;  3T02 A;  3A52 A;  5L0K A;  1EW9 A;  4KJG A;  4MY4 A;  3NKN A;  4UOR A;  5EGE A;  4KJD A;  3WAV A;  3UN5 A;  4NWJ A;  2XR9 A;  1KH5 A;  3NKP A;  5K4P A;  1ANI A;  1K7H A;  4LR9 A;  5KXA A;  4LR7 A;  4CYR A;  3OT9 A;  4LRA A;  1EJJ A;  5AJ9 A;  1FSU A;  4GTX A;  1KHJ A;  4MHX A;  1E33 P;  2W8D A;  4NWX A;  2W5T A;  4CXK A;  1Y7A A;  3B5Q A;  1ELX A;  2W8S A;  4GTZ A;  1URA A;  2IUC B;  3T01 A;  1P49 A;  4MIV A;  4KM4 A;  3BDG A;  1EI6 A;  3NVL A;  4ZG6 A;  5DLV A;  3IDD A;  2GSN A;  2W5X A;  2IFY A;  5DLW A;  4FDJ A;  3ED4 A;  1ZEB A;  5LIA A;  3UN2 A;  2GSO A;  1ALH A;  4GTW A;  4GTY A;  5LRM A;  4ZG7 A;  1AJA A;  3WBH A;  4UOO A;  3DPC A;  3UNY A;  5LQQ A;  5TJ3 A;  3WAX A;  1KH4 A;  3M8Y A;  4QAX A;  1KHL A;  4N7T A;  1E3C P;  4LRB A;  3UO0 A;  5C66 A;  3LXQ A;  5HRT A;  1SHN A;  1HQA A;  2GLQ A;  4ZG9 A;  4LR8 A;  3DYC A;  1AJC A;  1URB A;  2G9Y A;  1Y6V A;  3Q3Q A;  4CXS A;  1HDH A;  1O98 A;  4CXU A;  1ED9 A;  2GA3 A;  1B8J A;  4LRF A;  4TN0 A;  3MK0 A;  1KH9 A;  4CYS A;  4KAV A;  1N2L A;  4LRC A;  5L0E A;  5L0B A;  1O99 A;  5IJQ A;  5DLT A;  2X98 A;  2QZU A;  3NKQ A;  4ZGA A;  1AUK A;  1ALK A;  3BDH A;  1ED8 A;  3T00 A;  4LQY A;  3IGY B;  3M8Z A;  1HJK A;  2W5W A;  4UPL A;  3TX0 A;  3WAY A;  2W5V A;  3NKR A;  2ANH A;  4FDI A;  2IUC A;  1EQJ A;  2W5Q A;  2XRG A;  1ZED A;  3WAW A;  1AJB A;  4YR1 A;  5LRN A;  1ALI A;  3TG0 A;  1KHN A;  3MK2 A;  4B56 A;  1ZEF A;  3KD8 A;  4UPI A;  3CMR A;  2GSU A;  2W5S A;  3BDF A;  3BDG B;  3IGZ B;  4UOP A;  2RH6 A;  1KHK A;  4LR2 A;  5IJS A;  5INH A;  4LRE A;  4UPK A;  1EW8 A;  2W5R A;  3M8W A;  5GOV A;  5EGH A;  1E2S P;  3UN3 A;  1AJD A;  1ELZ A; 
#chains in the Genus database with same CATH homology
 1ANJ A;  2ZKT A;  4UPH A;  3E2D A;  5GRR A;  3M7V A;  3TWZ A;  3SZZ A;  1KH7 A;  1ALJ A;  3MK1 A;  1N2K A;  3SZY A;  2D1G A;  3NKO A;  1SHQ A;  3NKM A;  1ELY A;  1EW2 A;  1E1Z P;  2VQR A;  4KAY A;  4LRD A;  3T02 A;  3A52 A;  5L0K A;  1EW9 A;  4KJG A;  4MY4 A;  3NKN A;  4UOR A;  5EGE A;  4KJD A;  3WAV A;  3UN5 A;  4NWJ A;  2XR9 A;  1KH5 A;  3NKP A;  5K4P A;  1ANI A;  1K7H A;  4LR9 A;  5KXA A;  4LR7 A;  4CYR A;  3OT9 A;  4LRA A;  1EJJ A;  5AJ9 A;  1FSU A;  4GTX A;  1KHJ A;  4MHX A;  1E33 P;  2W8D A;  4NWX A;  2W5T A;  4CXK A;  1Y7A A;  3B5Q A;  1ELX A;  2W8S A;  4GTZ A;  1URA A;  2IUC B;  3T01 A;  1P49 A;  4MIV A;  4KM4 A;  3BDG A;  1EI6 A;  3NVL A;  4ZG6 A;  5DLV A;  3IDD A;  2GSN A;  2W5X A;  2IFY A;  5DLW A;  4FDJ A;  3ED4 A;  1ZEB A;  5LIA A;  3UN2 A;  2GSO A;  1ALH A;  4GTW A;  4GTY A;  5LRM A;  4ZG7 A;  1AJA A;  3WBH A;  4UOO A;  3DPC A;  3UNY A;  5LQQ A;  5TJ3 A;  3WAX A;  1KH4 A;  3M8Y A;  4QAX A;  1KHL A;  4N7T A;  1E3C P;  4LRB A;  3UO0 A;  5C66 A;  3LXQ A;  5HRT A;  1SHN A;  1HQA A;  2GLQ A;  4ZG9 A;  4LR8 A;  3DYC A;  1AJC A;  1URB A;  2G9Y A;  1Y6V A;  3Q3Q A;  4CXS A;  1HDH A;  1O98 A;  4CXU A;  1ED9 A;  2GA3 A;  1B8J A;  4LRF A;  4TN0 A;  3MK0 A;  1KH9 A;  4CYS A;  4KAV A;  1N2L A;  4LRC A;  5L0E A;  5L0B A;  1O99 A;  5IJQ A;  5DLT A;  2X98 A;  2QZU A;  3NKQ A;  4ZGA A;  1AUK A;  1ALK A;  3BDH A;  1ED8 A;  3T00 A;  4LQY A;  3IGY B;  3M8Z A;  1HJK A;  2W5W A;  4UPL A;  3TX0 A;  3WAY A;  2W5V A;  3NKR A;  2ANH A;  4FDI A;  2IUC A;  1EQJ A;  2W5Q A;  2XRG A;  1ZED A;  3WAW A;  1AJB A;  4YR1 A;  5LRN A;  1ALI A;  3TG0 A;  1KHN A;  3MK2 A;  4B56 A;  1ZEF A;  3KD8 A;  4UPI A;  3CMR A;  2GSU A;  2W5S A;  3BDF A;  3BDG B;  3IGZ B;  4UOP A;  2RH6 A;  1KHK A;  4LR2 A;  5IJS A;  5INH A;  4LRE A;  4UPK A;  1EW8 A;  2W5R A;  3M8W A;  5GOV A;  5EGH A;  1E2S P;  3UN3 A;  1AJD A;  1ELZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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