4MY4 | Genus

Total Genus 192

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	192
Knots found	KnotProt 2.0: S +3₁
sequence length	503
structure length	503
Chain Sequence	KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism pubmed doi rcsb
molecule keywords	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
molecule tags	Isomerase
source organism	Staphylococcus aureus subsp. aureus
total genus	192
structure length	503
sequence length	503
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date	2013-09-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01676	Metalloenzyme	Metalloenzyme superfamily
A	PF06415	iPGM_N	BPG-independent PGAM N-terminus (iPGM_N)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	4my4A01
3.40.1450.10	Alpha Beta	3-Layer(aba) Sandwich	2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	BPG-independent phosphoglycerate mutase, domain B	4my4A02

1AJBA 2ANHA 1URAA 3SZZA 2X98A 4MY4A 1ED8A 5GRRA 2XR9A 3M8ZA 3UN3A 1KHNA 1ZEDA 1ANIA 1ALHA 3CMRA 4LRFA 3T02A 2RH6A 1EW9A 2G9YA 4ZG6A 3BDFA 2VQRA 3NKRA 1KHLA 3WAVA 1ANJA 5L0KA 1E2SP 3UN5A 4KJDA 2D1GA 3WAXA 1ZEBA 5IJSA 3MK2A 3IGYB 4GTXA 1ED9A 4KM4A 2W5WA 3DPCA 4UPKA 3DYCA 1N2KA 2IFYA 4FDIA 5LQQA 3MK0A 5L0EA 1O98A 5AJ9A 1ZEFA 3NVLA 3UO0A 1HJKA 4KJGA 4LQYA 2W5TA 1EJJA 1KHJA 1Y7AA 5TJ3A 3TX0A 1AUKA 5DLWA 4NWXA 1EW2A 2QZUA 2W5VA 3M7VA 4GTZA 4LR7A 5LRMA 3NKMA 1HDHA 1EI6A 3LXQA 1HQAA 4UOPA 1ALKA 4N7TA 1EW8A 5LRNA 1ELXA 3BDGB 4LREA 3WAYA 4ZG7A 5GOVA 3NKNA 4UPHA 3IGZB 3E2DA 3NKPA 5DLTA 4YR1A 4QAXA 4LR8A 1E1ZP 3NKOA 4LR2A 4UOOA 1E33P 4MIVA 1AJCA 3T01A 4LRBA 1N2LA 3WAWA 1ELYA 5EGHA 1SHQA 4CXUA 4CYSA 1ALJA 4CXKA 1ELZA 4CXSA 2W8DA 1AJAA 2XRGA 1URBA 4CYRA 3BDHA 5KXAA 5LIAA 4ZGAA 4LR9A 4UPLA 1B8JA 1P49A 3T00A 2W5QA 4ZG9A 1SHNA 4KAVA 2IUCA 4LRAA 3M8YA 2W5SA 4NWJA 1Y6VA 3Q3QA 2GA3A 4FDJA 4MHXA 4B56A 3TG0A 5HRTA 3UN2A 4LRDA 1KH9A 1ALIA 1EQJA 5EGEA 3TWZA 3WBHA 1KH4A 3ED4A 1AJDA 3KD8A 5INHA 5L0BA 1KH5A 4UPIA 2W5RA 5IJQA 1E3CP 2GSUA 4GTYA 1FSUA 2ZKTA 5K4PA 4LRCA 1K7HA 1KH7A 3A52A 2GSNA 1KHKA 2W5XA 2GLQA 3B5QA 3BDGA 3OT9A 3IDDA 2GSOA 3SZYA 4GTWA 4KAYA 3MK1A 3M8WA 5DLVA 1O99A 4UORA 3UNYA 2W8SA 4TN0A 2IUCB 5C66A 3NKQA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1AJB A;  2ANH A;  1URA A;  3SZZ A;  2X98 A;  4MY4 A;  1ED8 A;  5GRR A;  2XR9 A;  3M8Z A;  3UN3 A;  1KHN A;  1ZED A;  1ANI A;  1ALH A;  3CMR A;  4LRF A;  3T02 A;  2RH6 A;  1EW9 A;  2G9Y A;  4ZG6 A;  3BDF A;  2VQR A;  3NKR A;  1KHL A;  3WAV A;  1ANJ A;  5L0K A;  1E2S P;  3UN5 A;  4KJD A;  2D1G A;  3WAX A;  1ZEB A;  5IJS A;  3MK2 A;  3IGY B;  4GTX A;  1ED9 A;  4KM4 A;  2W5W A;  3DPC A;  4UPK A;  3DYC A;  1N2K A;  2IFY A;  4FDI A;  5LQQ A;  3MK0 A;  5L0E A;  1O98 A;  5AJ9 A;  1ZEF A;  3NVL A;  3UO0 A;  1HJK A;  4KJG A;  4LQY A;  2W5T A;  1EJJ A;  1KHJ A;  1Y7A A;  5TJ3 A;  3TX0 A;  1AUK A;  5DLW A;  4NWX A;  1EW2 A;  2QZU A;  2W5V A;  3M7V A;  4GTZ A;  4LR7 A;  5LRM A;  3NKM A;  1HDH A;  1EI6 A;  3LXQ A;  1HQA A;  4UOP A;  1ALK A;  4N7T A;  1EW8 A;  5LRN A;  1ELX A;  3BDG B;  4LRE A;  3WAY A;  4ZG7 A;  5GOV A;  3NKN A;  4UPH A;  3IGZ B;  3E2D A;  3NKP A;  5DLT A;  4YR1 A;  4QAX A;  4LR8 A;  1E1Z P;  3NKO A;  4LR2 A;  4UOO A;  1E33 P;  4MIV A;  1AJC A;  3T01 A;  4LRB A;  1N2L A;  3WAW A;  1ELY A;  5EGH A;  1SHQ A;  4CXU A;  4CYS A;  1ALJ A;  4CXK A;  1ELZ A;  4CXS A;  2W8D A;  1AJA A;  2XRG A;  1URB A;  4CYR A;  3BDH A;  5KXA A;  5LIA A;  4ZGA A;  4LR9 A;  4UPL A;  1B8J A;  1P49 A;  3T00 A;  2W5Q A;  4ZG9 A;  1SHN A;  4KAV A;  2IUC A;  4LRA A;  3M8Y A;  2W5S A;  4NWJ A;  1Y6V A;  3Q3Q A;  2GA3 A;  4FDJ A;  4MHX A;  4B56 A;  3TG0 A;  5HRT A;  3UN2 A;  4LRD A;  1KH9 A;  1ALI A;  1EQJ A;  5EGE A;  3TWZ A;  3WBH A;  1KH4 A;  3ED4 A;  1AJD A;  3KD8 A;  5INH A;  5L0B A;  1KH5 A;  4UPI A;  2W5R A;  5IJQ A;  1E3C P;  2GSU A;  4GTY A;  1FSU A;  2ZKT A;  5K4P A;  4LRC A;  1K7H A;  1KH7 A;  3A52 A;  2GSN A;  1KHK A;  2W5X A;  2GLQ A;  3B5Q A;  3BDG A;  3OT9 A;  3IDD A;  2GSO A;  3SZY A;  4GTW A;  4KAY A;  3MK1 A;  3M8W A;  5DLV A;  1O99 A;  4UOR A;  3UNY A;  2W8S A;  4TN0 A;  2IUC B;  5C66 A;  3NKQ A; 
#chains in the Genus database with same CATH topology
 1AJB A;  2ANH A;  1URA A;  3SZZ A;  2X98 A;  4MY4 A;  1ED8 A;  5GRR A;  2XR9 A;  3M8Z A;  3UN3 A;  1KHN A;  1ZED A;  1ANI A;  1ALH A;  3CMR A;  4LRF A;  3T02 A;  2RH6 A;  1EW9 A;  2G9Y A;  4ZG6 A;  3BDF A;  2VQR A;  3NKR A;  1KHL A;  3WAV A;  1ANJ A;  5L0K A;  1E2S P;  3UN5 A;  4KJD A;  2D1G A;  3WAX A;  1ZEB A;  5IJS A;  3MK2 A;  3IGY B;  4GTX A;  1ED9 A;  4KM4 A;  2W5W A;  3DPC A;  4UPK A;  3DYC A;  1N2K A;  2IFY A;  4FDI A;  5LQQ A;  3MK0 A;  5L0E A;  1O98 A;  5AJ9 A;  1ZEF A;  3NVL A;  3UO0 A;  1HJK A;  4KJG A;  4LQY A;  2W5T A;  1EJJ A;  1KHJ A;  1Y7A A;  5TJ3 A;  3TX0 A;  1AUK A;  5DLW A;  4NWX A;  1EW2 A;  2QZU A;  2W5V A;  3M7V A;  4GTZ A;  4LR7 A;  5LRM A;  3NKM A;  1HDH A;  1EI6 A;  3LXQ A;  1HQA A;  4UOP A;  1ALK A;  4N7T A;  1EW8 A;  5LRN A;  1ELX A;  3BDG B;  4LRE A;  3WAY A;  4ZG7 A;  5GOV A;  3NKN A;  4UPH A;  3IGZ B;  3E2D A;  3NKP A;  5DLT A;  4YR1 A;  4QAX A;  4LR8 A;  1E1Z P;  3NKO A;  4LR2 A;  4UOO A;  1E33 P;  4MIV A;  1AJC A;  3T01 A;  4LRB A;  1N2L A;  3WAW A;  1ELY A;  5EGH A;  1SHQ A;  4CXU A;  4CYS A;  1ALJ A;  4CXK A;  1ELZ A;  4CXS A;  2W8D A;  1AJA A;  2XRG A;  1URB A;  4CYR A;  3BDH A;  5KXA A;  5LIA A;  4ZGA A;  4LR9 A;  4UPL A;  1B8J A;  1P49 A;  3T00 A;  2W5Q A;  4ZG9 A;  1SHN A;  4KAV A;  2IUC A;  4LRA A;  3M8Y A;  2W5S A;  4NWJ A;  1Y6V A;  3Q3Q A;  2GA3 A;  4FDJ A;  4MHX A;  4B56 A;  3TG0 A;  5HRT A;  3UN2 A;  4LRD A;  1KH9 A;  1ALI A;  1EQJ A;  5EGE A;  3TWZ A;  3WBH A;  1KH4 A;  3ED4 A;  1AJD A;  3KD8 A;  5INH A;  5L0B A;  1KH5 A;  4UPI A;  2W5R A;  5IJQ A;  1E3C P;  2GSU A;  4GTY A;  1FSU A;  2ZKT A;  5K4P A;  4LRC A;  1K7H A;  1KH7 A;  3A52 A;  2GSN A;  1KHK A;  2W5X A;  2GLQ A;  3B5Q A;  3BDG A;  3OT9 A;  3IDD A;  2GSO A;  3SZY A;  4GTW A;  4KAY A;  3MK1 A;  3M8W A;  5DLV A;  1O99 A;  4UOR A;  3UNY A;  2W8S A;  4TN0 A;  2IUC B;  5C66 A;  3NKQ A; 
#chains in the Genus database with same CATH homology
 1AJB A;  2ANH A;  1URA A;  3SZZ A;  2X98 A;  4MY4 A;  1ED8 A;  5GRR A;  2XR9 A;  3M8Z A;  3UN3 A;  1KHN A;  1ZED A;  1ANI A;  1ALH A;  3CMR A;  4LRF A;  3T02 A;  2RH6 A;  1EW9 A;  2G9Y A;  4ZG6 A;  3BDF A;  2VQR A;  3NKR A;  1KHL A;  3WAV A;  1ANJ A;  5L0K A;  1E2S P;  3UN5 A;  4KJD A;  2D1G A;  3WAX A;  1ZEB A;  5IJS A;  3MK2 A;  3IGY B;  4GTX A;  1ED9 A;  4KM4 A;  2W5W A;  3DPC A;  4UPK A;  3DYC A;  1N2K A;  2IFY A;  4FDI A;  5LQQ A;  3MK0 A;  5L0E A;  1O98 A;  5AJ9 A;  1ZEF A;  3NVL A;  3UO0 A;  1HJK A;  4KJG A;  4LQY A;  2W5T A;  1EJJ A;  1KHJ A;  1Y7A A;  5TJ3 A;  3TX0 A;  1AUK A;  5DLW A;  4NWX A;  1EW2 A;  2QZU A;  2W5V A;  3M7V A;  4GTZ A;  4LR7 A;  5LRM A;  3NKM A;  1HDH A;  1EI6 A;  3LXQ A;  1HQA A;  4UOP A;  1ALK A;  4N7T A;  1EW8 A;  5LRN A;  1ELX A;  3BDG B;  4LRE A;  3WAY A;  4ZG7 A;  5GOV A;  3NKN A;  4UPH A;  3IGZ B;  3E2D A;  3NKP A;  5DLT A;  4YR1 A;  4QAX A;  4LR8 A;  1E1Z P;  3NKO A;  4LR2 A;  4UOO A;  1E33 P;  4MIV A;  1AJC A;  3T01 A;  4LRB A;  1N2L A;  3WAW A;  1ELY A;  5EGH A;  1SHQ A;  4CXU A;  4CYS A;  1ALJ A;  4CXK A;  1ELZ A;  4CXS A;  2W8D A;  1AJA A;  2XRG A;  1URB A;  4CYR A;  3BDH A;  5KXA A;  5LIA A;  4ZGA A;  4LR9 A;  4UPL A;  1B8J A;  1P49 A;  3T00 A;  2W5Q A;  4ZG9 A;  1SHN A;  4KAV A;  2IUC A;  4LRA A;  3M8Y A;  2W5S A;  4NWJ A;  1Y6V A;  3Q3Q A;  2GA3 A;  4FDJ A;  4MHX A;  4B56 A;  3TG0 A;  5HRT A;  3UN2 A;  4LRD A;  1KH9 A;  1ALI A;  1EQJ A;  5EGE A;  3TWZ A;  3WBH A;  1KH4 A;  3ED4 A;  1AJD A;  3KD8 A;  5INH A;  5L0B A;  1KH5 A;  4UPI A;  2W5R A;  5IJQ A;  1E3C P;  2GSU A;  4GTY A;  1FSU A;  2ZKT A;  5K4P A;  4LRC A;  1K7H A;  1KH7 A;  3A52 A;  2GSN A;  1KHK A;  2W5X A;  2GLQ A;  3B5Q A;  3BDG A;  3OT9 A;  3IDD A;  2GSO A;  3SZY A;  4GTW A;  4KAY A;  3MK1 A;  3M8W A;  5DLV A;  1O99 A;  4UOR A;  3UNY A;  2W8S A;  4TN0 A;  2IUC B;  5C66 A;  3NKQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4MY4A

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations